Michael Hultström
Translationella studier av organsvikt under intensivvård.
Vårt lab fokuserar på translationella studier av organsvikt under intensivvård. Vi är speciellt intresserade av elektrolyt- och vätskebalans i relation till akut njurskada och hjärtsvikt. Dessutom är vi en del av Uppsala Intensivvårdsbiobank där vi också studerar orsaker till kritisk sjukdom med fokus på blodförgiftning, akut andningssvikt och COVID-19. Slutligen deltar vi i storskaliga studier av genetiska riskfaktorer för kritisk sjukdom inom SweCovid (https://swecovid.org) och det internationella samarbetet COVID-19 Host Genetics Initiative (https://www.covid19hg.org).

Publikationer
Plasma expansion and renal perfusion in critical COVID-19 with AKI: a prospective case control study
Ingår i Acta Anaesthesiologica Scandinavica, 2025
- DOI för Plasma expansion and renal perfusion in critical COVID-19 with AKI: a prospective case control study
- Ladda ner fulltext (pdf) av Plasma expansion and renal perfusion in critical COVID-19 with AKI: a prospective case control study
Ingår i Scientific Reports, 2025
- DOI för Alcohol consumption has a J-shaped association with bacterial infection and death due to infection, a population-based cohort study
- Ladda ner fulltext (pdf) av Alcohol consumption has a J-shaped association with bacterial infection and death due to infection, a population-based cohort study
Ingår i Nature Genetics, s. 345-357, 2025
- DOI för Integrative proteogenomic analysis identifies COL6A3-derived endotrophin as a mediator of the effect of obesity on coronary artery disease
- Ladda ner fulltext (pdf) av Integrative proteogenomic analysis identifies COL6A3-derived endotrophin as a mediator of the effect of obesity on coronary artery disease
Ingår i Physiological Genomics, s. 385-390, 2025
- DOI för A genetic variant associated with aquaporin 3 expression is correlated to in-hospital death in COVID-19 patients with extracellular hyperosmolality
- Ladda ner fulltext (pdf) av A genetic variant associated with aquaporin 3 expression is correlated to in-hospital death in COVID-19 patients with extracellular hyperosmolality
The 1-Year Functional Recovery From Severe COVID-19 in a Swedish Working-Age Cohort
Ingår i Acta Anaesthesiologica Scandinavica, 2025
- DOI för The 1-Year Functional Recovery From Severe COVID-19 in a Swedish Working-Age Cohort
- Ladda ner fulltext (pdf) av The 1-Year Functional Recovery From Severe COVID-19 in a Swedish Working-Age Cohort
Surviving COVID-19: patients' experiences of care and path to recovery
Ingår i International Journal of Qualitative Studies on Health and Well-being, 2024
- DOI för Surviving COVID-19: patients' experiences of care and path to recovery
- Ladda ner fulltext (pdf) av Surviving COVID-19: patients' experiences of care and path to recovery
Ingår i Critical Care, 2024
- DOI för Physical activity is associated with a lower risk of contracting and dying in infection and sepsis: a Swedish population-based cohort study
- Ladda ner fulltext (pdf) av Physical activity is associated with a lower risk of contracting and dying in infection and sepsis: a Swedish population-based cohort study
Plasma Biomarkers Associated to Outcome in Patients with Sars-Cov-2 Infection
Ingår i Journal of Clinical and Laboratory Medicine, 2024
Ingår i Journal of Clinical Medicine, 2024
- DOI för The Human Phospholipase B-II Precursor (HPLBII-P) in Urine as a Novel Biomarker of Glomerular Activity in COVID-19 and Diabetes Mellitus
- Ladda ner fulltext (pdf) av The Human Phospholipase B-II Precursor (HPLBII-P) in Urine as a Novel Biomarker of Glomerular Activity in COVID-19 and Diabetes Mellitus
Uromodulin in sepsis and severe pneumonia: a two-sample Mendelian randomization study
Ingår i Physiological Genomics, s. 409-416, 2024
Ingår i PLOS ONE, 2024
- DOI för Smoking is associated with higher risk of contracting bacterial infection and pneumonia, intensive care unit admission and death
- Ladda ner fulltext (pdf) av Smoking is associated with higher risk of contracting bacterial infection and pneumonia, intensive care unit admission and death
Ingår i Frontiers in Physiology, 2024
- DOI för Body mass index is associated with pulmonary gas and blood distribution mismatch in COVID-19 acute respiratory failure: A physiological study
- Ladda ner fulltext (pdf) av Body mass index is associated with pulmonary gas and blood distribution mismatch in COVID-19 acute respiratory failure: A physiological study
Ingår i Physiological Genomics, s. 483-491, 2024
Ingår i Intensive & Critical Care Nursing, 2024
- DOI för Returning to work and health status at 12 months among patients with COVID-19 cared for in intensive care: A prospective, longitudinal study
- Ladda ner fulltext (pdf) av Returning to work and health status at 12 months among patients with COVID-19 cared for in intensive care: A prospective, longitudinal study
Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunity
Ingår i Nature Communications, 2024
- DOI för Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunity
- Ladda ner fulltext (pdf) av Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunity
Ingår i Intensive Care Medicine Experimental, 2024
- DOI för Association of corticosteroid therapy with reduced acute kidney injury and lower NET markers in severe COVID-19: an observational study
- Ladda ner fulltext (pdf) av Association of corticosteroid therapy with reduced acute kidney injury and lower NET markers in severe COVID-19: an observational study
Ingår i Upsala Journal of Medical Sciences, 2024
- DOI för Lung function at 1-year follow-up in patients with persistent dyspnea after mild COVID-19: comparisons with moderate and critical COVID-19
- Ladda ner fulltext (pdf) av Lung function at 1-year follow-up in patients with persistent dyspnea after mild COVID-19: comparisons with moderate and critical COVID-19
Ingår i Cancers, 2024
- DOI för Tumor Predisposing Post-Zygotic Chromosomal Alterations in Bladder Cancer-Insights from Histologically Normal Urothelium
- Ladda ner fulltext (pdf) av Tumor Predisposing Post-Zygotic Chromosomal Alterations in Bladder Cancer-Insights from Histologically Normal Urothelium
Ingår i Acta Anaesthesiologica Scandinavica, s. 1417-1425, 2024
- DOI för Comorbid burden at ICU admission in COVID-19 compared to sepsis and acute respiratory distress syndrome
- Ladda ner fulltext (pdf) av Comorbid burden at ICU admission in COVID-19 compared to sepsis and acute respiratory distress syndrome
Ingår i Acta Anaesthesiologica Scandinavica, s. 1561-1564, 2024
- DOI för Paediatric postoperative acute kidney injury after non-cardiac surgery: Protocol for a systematic review and meta-analysis
- Ladda ner fulltext (pdf) av Paediatric postoperative acute kidney injury after non-cardiac surgery: Protocol for a systematic review and meta-analysis
Ingår i The Lancet, s. 2100-2132, 2024
- DOI för Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021
- Ladda ner fulltext (pdf) av Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021
Ingår i The Lancet, s. 2204-2256, 2024
- DOI för Burden of disease scenarios for 204 countries and territories, 2022-2050: a forecasting analysis for the Global Burden of Disease Study 2021
- Ladda ner fulltext (pdf) av Burden of disease scenarios for 204 countries and territories, 2022-2050: a forecasting analysis for the Global Burden of Disease Study 2021
Ingår i The Lancet, s. 2162-2203, 2024
- DOI för Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021
- Ladda ner fulltext (pdf) av Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021
Ingår i The Lancet, s. 1989-2056, 2024
- DOI för Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950-2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
- Ladda ner fulltext (pdf) av Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950-2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
Bacteriuria and antibiotic use during the third wave of COVID-19 intensive care in Sweden
Ingår i Infectious Diseases, s. 284-293, 2024
- DOI för Bacteriuria and antibiotic use during the third wave of COVID-19 intensive care in Sweden
- Ladda ner fulltext (pdf) av Bacteriuria and antibiotic use during the third wave of COVID-19 intensive care in Sweden
Immuno-Modulatory Effects of Dexamethasone in Severe COVID-19: A Swedish Cohort Study
Ingår i Biomedicines, 2023
- DOI för Immuno-Modulatory Effects of Dexamethasone in Severe COVID-19: A Swedish Cohort Study
- Ladda ner fulltext (pdf) av Immuno-Modulatory Effects of Dexamethasone in Severe COVID-19: A Swedish Cohort Study
Ingår i Acta Anaesthesiologica Scandinavica, s. 213-220, 2023
- DOI för Estimated glomerular filtration rates are higher when creatinine-based equations are compared with a cystatin C-based equation in coronavirus disease 2019
- Ladda ner fulltext (pdf) av Estimated glomerular filtration rates are higher when creatinine-based equations are compared with a cystatin C-based equation in coronavirus disease 2019
Ingår i Cytokine, 2023
- DOI för Plasma cytokine levels in spinal surgery with sevoflurane or total intravenous propofol anesthesia: A post hoc analysis of a randomized controlled trial
- Ladda ner fulltext (pdf) av Plasma cytokine levels in spinal surgery with sevoflurane or total intravenous propofol anesthesia: A post hoc analysis of a randomized controlled trial
Ingår i Scientific Reports, 2023
- DOI för Central nervous system biomarkers GFAp and NfL associate with post-acute cognitive impairment and fatigue following critical COVID-19
- Ladda ner fulltext (pdf) av Central nervous system biomarkers GFAp and NfL associate with post-acute cognitive impairment and fatigue following critical COVID-19
Ingår i Biomedicines, 2023
- DOI för Analysis of Calprotectin as an Early Marker of Infections Is Economically Advantageous in Intensive Care-Treated Patients
- Ladda ner fulltext (pdf) av Analysis of Calprotectin as an Early Marker of Infections Is Economically Advantageous in Intensive Care-Treated Patients
Ingår i International Journal of Epidemiology, s. 1163-1174, 2023
Ingår i Irish Journal of Medical Science, s. 227-229, 2023
- DOI för Infectious SARS-CoV-2 is rarely present in the nasopharynx samples collected from Swedish hospitalized critically ill COVID-19 patients
- Ladda ner fulltext (pdf) av Infectious SARS-CoV-2 is rarely present in the nasopharynx samples collected from Swedish hospitalized critically ill COVID-19 patients
Ingår i Journal of Nuclear Medicine, s. 145-148, 2023
- DOI för In Vivo Visualization and Quantification of Neutrophil Elastase in Lungs of COVID-19 Patients: A First-in-Humans PET Study with 11C-NES
- Ladda ner fulltext (pdf) av In Vivo Visualization and Quantification of Neutrophil Elastase in Lungs of COVID-19 Patients: A First-in-Humans PET Study with 11C-NES
Ingår i PLOS ONE, 2023
- DOI för Prior physical illness predicts death better than acute physiological derangement on intensive care unit admission in COVID-19: A Swedish registry study
- Ladda ner fulltext (pdf) av Prior physical illness predicts death better than acute physiological derangement on intensive care unit admission in COVID-19: A Swedish registry study
Postoperative acute kidney injury after volatile or intravenous anesthesia: a meta-analysis
Ingår i American Journal of Physiology - Renal Physiology, 2023
Ingår i European Journal of Anaesthesiology, s. 13-20, 2023
A second update on mapping the human genetic architecture of COVID-19
Ingår i Nature, 2023
- DOI för A second update on mapping the human genetic architecture of COVID-19
- Ladda ner fulltext (pdf) av A second update on mapping the human genetic architecture of COVID-19
Global Burden of Cardiovascular Diseases and Risks, 1990-2022
Ingår i Journal of the American College of Cardiology, s. 2350-2473, 2023
Ingår i European Journal of Trauma and Emergency Surgery, s. 1303-1313, 2023
- DOI för Intermittent thoracic resuscitative endovascular balloon occlusion of the aorta improves renal function compared to 60 min continuous application after porcine class III hemorrhage
- Ladda ner fulltext (pdf) av Intermittent thoracic resuscitative endovascular balloon occlusion of the aorta improves renal function compared to 60 min continuous application after porcine class III hemorrhage
Diagnostic Values of METTL1-Related Genes and Immune Characteristics in Systemic Lupus Erythematosus
Ingår i Journal of Inflammation Research, s. 5367-5383, 2023
- DOI för Diagnostic Values of METTL1-Related Genes and Immune Characteristics in Systemic Lupus Erythematosus
- Ladda ner fulltext (pdf) av Diagnostic Values of METTL1-Related Genes and Immune Characteristics in Systemic Lupus Erythematosus
Ingår i Nature Metabolism, s. 248-264, 2023
Ingår i Scientific Reports, 2023
- DOI för Health-related quality of life after surviving intensive care for COVID-19: a prospective multicenter cohort study
- Ladda ner fulltext (pdf) av Health-related quality of life after surviving intensive care for COVID-19: a prospective multicenter cohort study
Ingår i Frontiers in Medicine, 2023
- DOI för Antibiotic use during coronavirus disease 2019 intensive care unit shape multidrug resistance bacteriuria: A Swedish longitudinal prospective study
- Ladda ner fulltext (pdf) av Antibiotic use during coronavirus disease 2019 intensive care unit shape multidrug resistance bacteriuria: A Swedish longitudinal prospective study
Poor long-term recovery after critical COVID-19 during 12 months longitudinal follow-up
Ingår i Intensive & Critical Care Nursing, 2023
- DOI för Poor long-term recovery after critical COVID-19 during 12 months longitudinal follow-up
- Ladda ner fulltext (pdf) av Poor long-term recovery after critical COVID-19 during 12 months longitudinal follow-up
Ingår i Communications Biology, 2023
- DOI för HLA allele-calling using multi-ancestry whole-exome sequencing from the UK Biobank identifies 129 novel associations in 11 autoimmune diseases
- Ladda ner fulltext (pdf) av HLA allele-calling using multi-ancestry whole-exome sequencing from the UK Biobank identifies 129 novel associations in 11 autoimmune diseases
Ingår i Critical Care, 2022
- DOI för Dehydration is associated with production of organic osmolytes and predicts physical long-term symptoms after COVID-19: a multicenter cohort study
- Ladda ner fulltext (pdf) av Dehydration is associated with production of organic osmolytes and predicts physical long-term symptoms after COVID-19: a multicenter cohort study
Ingår i Biomedicines, 2022
- DOI för Differential Bias for Creatinine- and Cystatin C- Derived Estimated Glomerular Filtration Rate in Critical COVID-19.
- Ladda ner fulltext (pdf) av Differential Bias for Creatinine- and Cystatin C- Derived Estimated Glomerular Filtration Rate in Critical COVID-19.
Ingår i Journal of neuroradiology, s. 421-427, 2022
- DOI för The extent of neuroradiological findings in COVID-19 shows correlation with blood biomarkers, Glasgow coma scale score and days in intensive care
- Ladda ner fulltext (pdf) av The extent of neuroradiological findings in COVID-19 shows correlation with blood biomarkers, Glasgow coma scale score and days in intensive care
Shrunken Pore Syndrome Is Frequently Occurring in Severe COVID-19
Ingår i International Journal of Molecular Sciences, 2022
- DOI för Shrunken Pore Syndrome Is Frequently Occurring in Severe COVID-19
- Ladda ner fulltext (pdf) av Shrunken Pore Syndrome Is Frequently Occurring in Severe COVID-19
Ingår i Critical Care, 2022
- DOI för Decreased renal perfusion during acute kidney injury in critical COVID-19 assessed by magnetic resonance imaging: a prospective case control study
- Ladda ner fulltext (pdf) av Decreased renal perfusion during acute kidney injury in critical COVID-19 assessed by magnetic resonance imaging: a prospective case control study