Michael Williams
Forskare vid Institutionen för kirurgiska vetenskaper; Funktionell farmakologi och neurovetenskap
- E-post:
- michael.williams@uu.se
- Besöksadress:
- BMC, Husargatan 3
751 24 Uppsala - Postadress:
- Kirurgiska vetenskaper, Box 593
751 24 Uppsala
- Akademiska meriter:
- PhD

Publikationer
Senaste publikationer
Off-target effects of statins: molecular mechanisms, side effects and the emerging role of kinases
Ingår i British Journal of Pharmacology, s. 3799-3818, 2024
- DOI för Off-target effects of statins: molecular mechanisms, side effects and the emerging role of kinases
- Ladda ner fulltext (pdf) av Off-target effects of statins: molecular mechanisms, side effects and the emerging role of kinases
Ingår i Science of the Total Environment, s. 177472, 2024
Ingår i Scientific Reports, 2024
- DOI för Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes
- Ladda ner fulltext (pdf) av Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes
Evidence for Prepulse Inhibition of Visually Evoked Motor Response in Drosophila melanogaster
Ingår i Biology, 2023
- DOI för Evidence for Prepulse Inhibition of Visually Evoked Motor Response in Drosophila melanogaster
- Ladda ner fulltext (pdf) av Evidence for Prepulse Inhibition of Visually Evoked Motor Response in Drosophila melanogaster
Ingår i Biomedicines, 2023
- DOI för Drosophila as a Rapid Screening Model to Evaluate the Hypoglycemic Effects of Dipeptidyl Peptidase 4 (DPP4) Inhibitors: High Evolutionary Conservation of DPP4
- Ladda ner fulltext (pdf) av Drosophila as a Rapid Screening Model to Evaluate the Hypoglycemic Effects of Dipeptidyl Peptidase 4 (DPP4) Inhibitors: High Evolutionary Conservation of DPP4
Alla publikationer
Artiklar i tidskrift
Off-target effects of statins: molecular mechanisms, side effects and the emerging role of kinases
Ingår i British Journal of Pharmacology, s. 3799-3818, 2024
- DOI för Off-target effects of statins: molecular mechanisms, side effects and the emerging role of kinases
- Ladda ner fulltext (pdf) av Off-target effects of statins: molecular mechanisms, side effects and the emerging role of kinases
Ingår i Science of the Total Environment, s. 177472, 2024
Ingår i Scientific Reports, 2024
- DOI för Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes
- Ladda ner fulltext (pdf) av Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes
Evidence for Prepulse Inhibition of Visually Evoked Motor Response in Drosophila melanogaster
Ingår i Biology, 2023
- DOI för Evidence for Prepulse Inhibition of Visually Evoked Motor Response in Drosophila melanogaster
- Ladda ner fulltext (pdf) av Evidence for Prepulse Inhibition of Visually Evoked Motor Response in Drosophila melanogaster
Ingår i Biomedicines, 2023
- DOI för Drosophila as a Rapid Screening Model to Evaluate the Hypoglycemic Effects of Dipeptidyl Peptidase 4 (DPP4) Inhibitors: High Evolutionary Conservation of DPP4
- Ladda ner fulltext (pdf) av Drosophila as a Rapid Screening Model to Evaluate the Hypoglycemic Effects of Dipeptidyl Peptidase 4 (DPP4) Inhibitors: High Evolutionary Conservation of DPP4
Ingår i Biomedicines, 2023
- DOI för Effects of Transient Administration of the NMDA Receptor Antagonist MK-801 in Drosophila melanogaster Activity, Sleep, and Negative Geotaxis
- Ladda ner fulltext (pdf) av Effects of Transient Administration of the NMDA Receptor Antagonist MK-801 in Drosophila melanogaster Activity, Sleep, and Negative Geotaxis
The Statin Target HMG-Coenzyme a Reductase (Hmgcr) Regulates Sleep Homeostasis in Drosophila
Ingår i Pharmaceuticals, 2022
- DOI för The Statin Target HMG-Coenzyme a Reductase (Hmgcr) Regulates Sleep Homeostasis in Drosophila
- Ladda ner fulltext (pdf) av The Statin Target HMG-Coenzyme a Reductase (Hmgcr) Regulates Sleep Homeostasis in Drosophila
The Statin Target Hmgcr Regulates Energy Metabolism and Food Intake through Central Mechanisms
Ingår i Cells, 2022
- DOI för The Statin Target Hmgcr Regulates Energy Metabolism and Food Intake through Central Mechanisms
- Ladda ner fulltext (pdf) av The Statin Target Hmgcr Regulates Energy Metabolism and Food Intake through Central Mechanisms
Ingår i Molecules, 2022
- DOI för Enhanced Toxicity of Bisphenols Together with UV Filters in Water: Identification of Synergy and Antagonism in Three-Component Mixtures
- Ladda ner fulltext (pdf) av Enhanced Toxicity of Bisphenols Together with UV Filters in Water: Identification of Synergy and Antagonism in Three-Component Mixtures
Ingår i Cells, 2022
- DOI för Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes
- Ladda ner fulltext (pdf) av Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes
Ingår i Membranes, 2021
- DOI för Multidrug Resistance Like Protein 1 Activity in Malpighian Tubules Regulates Lipid Homeostasis in Drosophila
- Ladda ner fulltext (pdf) av Multidrug Resistance Like Protein 1 Activity in Malpighian Tubules Regulates Lipid Homeostasis in Drosophila
Ingår i Insects, 2021
- DOI för The Fly Homologue of MFSD11 Is Possibly Linked to Nutrient Homeostasis and Has a Potential Role in Locomotion: A First Characterization of the Atypical Solute Carrier CG18549 in Drosophila Melanogaster
- Ladda ner fulltext (pdf) av The Fly Homologue of MFSD11 Is Possibly Linked to Nutrient Homeostasis and Has a Potential Role in Locomotion: A First Characterization of the Atypical Solute Carrier CG18549 in Drosophila Melanogaster
Ingår i Frontiers in Bioscience-Landmark, s. 1453-1463, 2021
- DOI för Differential associations of statin treatment and polymorphism in genes coding for HMGCR and PCSK9 to risk for insomnia
- Ladda ner fulltext (pdf) av Differential associations of statin treatment and polymorphism in genes coding for HMGCR and PCSK9 to risk for insomnia
Ingår i Frontiers in Neuroscience, 2021
- DOI för The Drosophila melanogaster Levodopa-Induced Depression Model Exhibits Negative Geotaxis Deficits and Differential Gene Expression in Males and Females
- Ladda ner fulltext (pdf) av The Drosophila melanogaster Levodopa-Induced Depression Model Exhibits Negative Geotaxis Deficits and Differential Gene Expression in Males and Females
Dibutyl phthalate disrupts conserved circadian rhythm in Drosophila and human cells
Ingår i Science of the Total Environment, 2021
- DOI för Dibutyl phthalate disrupts conserved circadian rhythm in Drosophila and human cells
- Ladda ner fulltext (pdf) av Dibutyl phthalate disrupts conserved circadian rhythm in Drosophila and human cells
Ingår i Science of the Total Environment, 2021
Ingår i Cannabis and cannabinoid research, s. 119-136, 2021
Ingår i International Journal of Molecular Sciences, 2021
- DOI för Integrating Statistical and Machine-Learning Approach for Meta-Analysis of Bisphenol A-Exposure Datasets Reveals Effects on Mouse Gene Expression within Pathways of Apoptosis and Cell Survival
- Ladda ner fulltext (pdf) av Integrating Statistical and Machine-Learning Approach for Meta-Analysis of Bisphenol A-Exposure Datasets Reveals Effects on Mouse Gene Expression within Pathways of Apoptosis and Cell Survival
The Cognitive Effects of Statins are Modified by Age
Ingår i Scientific Reports, 2020
- DOI för The Cognitive Effects of Statins are Modified by Age
- Ladda ner fulltext (pdf) av The Cognitive Effects of Statins are Modified by Age
Ingår i Frontiers in Cell and Developmental Biology, 2020
- DOI för CG4928 is vital for renal function in fruit flies and membrane potential in cells: A first in-depth characterization of the putative Solute Carrier UNC93A
- Ladda ner fulltext (pdf) av CG4928 is vital for renal function in fruit flies and membrane potential in cells: A first in-depth characterization of the putative Solute Carrier UNC93A
Ingår i Environmental Science and Pollution Research, s. 25261-25270, 2020
- DOI för Exposure to the environmental pollutant bisphenol A diglycidyl ether (BADGE) causes cell over-proliferation in Drosophila
- Ladda ner fulltext (pdf) av Exposure to the environmental pollutant bisphenol A diglycidyl ether (BADGE) causes cell over-proliferation in Drosophila
Identification of reference markers for characterizing honey bee (Apis mellifera) hemocyte classes
Ingår i Developmental and Comparative Immunology, 2020
- DOI för Identification of reference markers for characterizing honey bee (Apis mellifera) hemocyte classes
- Ladda ner fulltext (pdf) av Identification of reference markers for characterizing honey bee (Apis mellifera) hemocyte classes
CCAP regulates feeding behavior via the NPF pathway in Drosophila adults
Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 7401-7408, 2020
Ingår i Translational Psychiatry, 2019
- DOI för Evidence that genes involved in hedgehog signaling are associated with both bipolar disorder and high BMI
- Ladda ner fulltext (pdf) av Evidence that genes involved in hedgehog signaling are associated with both bipolar disorder and high BMI
Ingår i Zebrafish, 2018
Genes encoding cuticular proteins are components of the Nimrod gene cluster in Drosophila
Ingår i Insect Biochemistry and Molecular Biology, s. 45-54, 2017
Ingår i Translational Psychiatry, 2017
- DOI för A methylome-wide mQTL analysis reveals associations of methylation sites with GAD1 and HDAC3 SNPs and a general psychiatric risk score
- Ladda ner fulltext (pdf) av A methylome-wide mQTL analysis reveals associations of methylation sites with GAD1 and HDAC3 SNPs and a general psychiatric risk score
Genetical Genomics of Behavior: A Novel Chicken Genomic Model for Anxiety Behavior
Ingår i Genetics, s. 327-+, 2016
Recurrent Sleep Fragmentation Induces Insulin and Neuroprotective Mechanisms in Middle-Aged Flies
Ingår i Frontiers in Aging Neuroscience, 2016
- DOI för Recurrent Sleep Fragmentation Induces Insulin and Neuroprotective Mechanisms in Middle-Aged Flies
- Ladda ner fulltext (pdf) av Recurrent Sleep Fragmentation Induces Insulin and Neuroprotective Mechanisms in Middle-Aged Flies
Ingår i Basic & Clinical Pharmacology & Toxicology, s. 309-316, 2016
The Drosophila ETV5 homologue Ets96B: Molecular link between obesity and bipolar disorder
Ingår i PLOS Genetics, 2016
- DOI för The Drosophila ETV5 homologue Ets96B: Molecular link between obesity and bipolar disorder
- Ladda ner fulltext (pdf) av The Drosophila ETV5 homologue Ets96B: Molecular link between obesity and bipolar disorder
Ingår i PLOS ONE, 2016
- DOI för The raspberry Gene Is Involved in the Regulation of the Cellular Immune Response in Drosophila melanogaster
- Ladda ner fulltext (pdf) av The raspberry Gene Is Involved in the Regulation of the Cellular Immune Response in Drosophila melanogaster
Ingår i Endocrinology, s. 2309-2321, 2016
The Drosophila ortholog of TMEM18 regulates insulin and glucagon-like signaling
Ingår i Journal of Endocrinology, s. 233-243, 2016
Implication of coronin 7 in body weight regulation in humans, mice and flies
Ingår i BMC Neuroscience, 2015
- DOI för Implication of coronin 7 in body weight regulation in humans, mice and flies
- Ladda ner fulltext (pdf) av Implication of coronin 7 in body weight regulation in humans, mice and flies
The obesity-linked Nudt3 Drosophila homolog Aps is associated with insulin signalling
Ingår i Molecular Endocrinology, s. 1303-1319, 2015
Evolutionary hierarchy of vertebrate-like heterotrimeric G protein families
Ingår i Molecular Phylogenetics and Evolution, s. 27-40, 2015
Ingår i BMC Evolutionary Biology, 2014
- DOI för The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals
- Ladda ner fulltext (pdf) av The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals
Cholecystokinin-Like Peptide (DSK) in Drosophila, Not Only for Satiety Signaling
Ingår i Frontiers in Endocrinology, s. 219, 2014
Obesity-linked homologues TfAP-2 and Twz establish meal frequency in Drosophila melanogaster
Ingår i PLOS Genetics, 2014
- DOI för Obesity-linked homologues TfAP-2 and Twz establish meal frequency in Drosophila melanogaster
- Ladda ner fulltext (pdf) av Obesity-linked homologues TfAP-2 and Twz establish meal frequency in Drosophila melanogaster
Ingår i PLOS ONE, 2014
- DOI för Drosophila Insulin-Producing Cells Are Differentially Modulated by Serotonin and Octopamine Receptors and Affect Social Behavior
- Ladda ner fulltext (pdf) av Drosophila Insulin-Producing Cells Are Differentially Modulated by Serotonin and Octopamine Receptors and Affect Social Behavior
The Drosophila Kctd-family homologue Kctd12-like modulates male aggression and mating behaviour
Ingår i European Journal of Neuroscience, s. 2513-2526, 2014
The Drosophila Small GTPase Rac2 is Required for Normal Feeding and Mating Behaviour.
Ingår i Behavior Genetics, s. 155-64, 2014
Exposure to Bisphenol A Affects Lipid Metabolism in Drosophila melanogaster
Ingår i Basic & Clinical Pharmacology & Toxicology, s. 414-420, 2014
Ingår i Genetics, s. 349-362, 2014
Ingår i Journal of Systematics and Evolution, s. 664-670, 2013
Real-time analysis of Drosophila post-embryonic haemocyte behaviour
Ingår i PLOS ONE, 2012
- DOI för Real-time analysis of Drosophila post-embryonic haemocyte behaviour
- Ladda ner fulltext (pdf) av Real-time analysis of Drosophila post-embryonic haemocyte behaviour
A directed miniscreen for genes involved in the Drosophila anti-parasitoid immune response
Ingår i Immunogenetics, s. 155-161, 2012
Ingår i Developmental and Comparative Immunology, s. 160-168, 2012
Ingår i Methods in molecular biology (Clifton, N.J.), s. 359-67, 2012
Ingår i Small GTPases, s. 201, 2012
The Rho-family GTPase Rac1 regulates integrin localization in Drosophila immunosurveillance cells
Ingår i PLOS ONE, 2011
Drosophila cellular immunity: a story of migration and adhesion
Ingår i Journal of Cell Science, s. 1373-1382, 2011
Artiklar, forskningsöversikt
Ingår i Journal of genetics and genomics = Yi chuan xue bao, s. 1-12, 2022
Ingår i Critical reviews in environmental science and technology, s. 4094-4112, 2022
- DOI för The potential interaction of environmental pollutants and circadian rhythm regulations that may cause leukemia
- Ladda ner fulltext (pdf) av The potential interaction of environmental pollutants and circadian rhythm regulations that may cause leukemia
Ingår i Cell & Bioscience, 2022
- DOI för The regulatory role of AP-2 beta in monoaminergic neurotransmitter systems: insights on its signalling pathway, linked disorders and theragnostic potential
- Ladda ner fulltext (pdf) av The regulatory role of AP-2 beta in monoaminergic neurotransmitter systems: insights on its signalling pathway, linked disorders and theragnostic potential
Role of the synergistic interactions of environmental pollutants in the development of cancer
Ingår i GeoHealth, 2022
- DOI för Role of the synergistic interactions of environmental pollutants in the development of cancer
- Ladda ner fulltext (pdf) av Role of the synergistic interactions of environmental pollutants in the development of cancer
Ingår i Neuroscience and Biobehavioral Reviews, s. 1-12, 2021
- DOI för Rodent and fly models in behavioral neuroscience: An evaluation of methodological advances, comparative research, and future perspectives
- Ladda ner fulltext (pdf) av Rodent and fly models in behavioral neuroscience: An evaluation of methodological advances, comparative research, and future perspectives
The Synaptic Scaling Literature: A Systematic Review of Methodologies and Quality of Reporting
Ingår i Frontiers in Cellular Neuroscience, 2020
- DOI för The Synaptic Scaling Literature: A Systematic Review of Methodologies and Quality of Reporting
- Ladda ner fulltext (pdf) av The Synaptic Scaling Literature: A Systematic Review of Methodologies and Quality of Reporting
Neural Cotransmission in Spinal Circuits Governing Locomotion
Ingår i TINS - Trends in Neurosciences, s. 540-550, 2018
What model organisms and interactomics can reveal about the genetics of human obesity
Ingår i Cellular and Molecular Life Sciences (CMLS), s. 3819-3834, 2012