Malin Gingnell
Forskare vid Institutionen för medicinska vetenskaper; Experimentell kognitiv och affektiv neurovetenskap (ECAN)
- E-post:
- malin.gingnell@neuro.uu.se
- Besöksadress:
- Akademiska sjukhuset, ingång 10
- Postadress:
- Akademiska sjukhuset, ingång 10
751 85 UPPSALA
Gästforskare vid Institutionen för psykologi; Avdelningen för Emotionspsykologi
- E-post:
- malin.gingnell@psyk.uu.se
- Besöksadress:
- Von Kraemers allé 1A och 1C
752 37 Uppsala - Postadress:
- Box 1225
751 42 UPPSALA
Forskning
Experimental Cognitive and Affective Neuroscience –Lab
ECAN
With a background in neuroimaging, one foot in psychology and the other in medicine, the research within our group focuses on various aspects of neural processing in relation to affective stimuli as well as during cognitive tasks, both in one individual at a time and simultaneously during social interaction. This involves both studying healthy participants and clinical cohorts, in the lab or in more natural settings, as well as performing various treatment studies. Our methods include fMRI, PET, EEG, fNIRS and psychophysiological measurements.
The interplay between emotions and ovarian steroid hormones has been in particular focus, such as how the changes in sex hormone levels during puberty interacts with levels of anxiety.
In addition to this, we look at how profound changes in physiology (such as during hypoglycemia or after a sudden decrease in blood flow), as well as more subtle manipulations (such as the intake of caffeine) affect affective symptoms and brain function. Another research trajectory includes the mechanisms underlying treatment effects, both regarding pharmaceutical treatments such as SSRI, but also applying brain stimulating techniques such as ECT and TMS as well as therapeutic interventions such as CBT. In relation to the later, we do in-depth studies of especially the learning process during extinction, using conditioning as a proxy for mechanisms activated during exposure therapy or fear learning. We also conducted studies that explore the mechanisms behind the placebo effect, both in more general terms and in relation to affective disorders and the neurobiological features of curiosity and grief.
Data collection is performed in collaboration with several research groups at Uppsala University as well as together with international groups. As an example, the group is part of RE-MEND and UPIC and collaborates with the research centers WOMHER, CIRCUS and CMH. The team members also coordinate activity in anxiety - an interdisciplinary research network.
Lab leaders:
Malin Gingnell & Andreas Frick
Post docs:
Lykke Silfverbrand
PhD-students:
Magdalena Wlad
Ebba Widegren
Ashika Roy
Patricia Gil Paterna
Barry Karlsson
Carolina Knihs de Camargo
Carl Brandt
Sara Chergia
Kristina Stenström
Lab manager:
Hampus Berg
Lab assistants:
Vanessa Messinger
Felicia Pohl
Previously associated:
Matilda Frick, post doc (now at Stockholm University, Sweden)
Wiebke Struckmann, PhD (now at Stanford, USA)

Publikationer
Senaste publikationer
Fear extinction retention in children, adolescents, and adults
Ingår i Developmental Cognitive Neuroscience, 2025
- DOI för Fear extinction retention in children, adolescents, and adults
- Ladda ner fulltext (pdf) av Fear extinction retention in children, adolescents, and adults
A Japanese translation of the Swedish Universities Scales of Personality
Ingår i Upsala Journal of Medical Sciences, 2024
- DOI för A Japanese translation of the Swedish Universities Scales of Personality
- Ladda ner fulltext (pdf) av A Japanese translation of the Swedish Universities Scales of Personality
Ingår i Developmental Psychobiology, 2024
- DOI för The influence of anterior cingulate GABA+ and glutamate on emotion regulation and reactivity in adolescents and adults
- Ladda ner fulltext (pdf) av The influence of anterior cingulate GABA+ and glutamate on emotion regulation and reactivity in adolescents and adults
Ingår i BMC Psychiatry, 2024
- DOI för Allopregnanolone and progesterone in relation to a single electroconvulsive therapy seizure and subsequent clinical outcome: an observational cohort study
- Ladda ner fulltext (pdf) av Allopregnanolone and progesterone in relation to a single electroconvulsive therapy seizure and subsequent clinical outcome: an observational cohort study
Directed causal effect with PCMCI in hyperscanning EEG time series
Ingår i Frontiers in Neuroscience, 2024
- DOI för Directed causal effect with PCMCI in hyperscanning EEG time series
- Ladda ner fulltext (pdf) av Directed causal effect with PCMCI in hyperscanning EEG time series
Alla publikationer
Artiklar i tidskrift
Fear extinction retention in children, adolescents, and adults
Ingår i Developmental Cognitive Neuroscience, 2025
- DOI för Fear extinction retention in children, adolescents, and adults
- Ladda ner fulltext (pdf) av Fear extinction retention in children, adolescents, and adults
A Japanese translation of the Swedish Universities Scales of Personality
Ingår i Upsala Journal of Medical Sciences, 2024
- DOI för A Japanese translation of the Swedish Universities Scales of Personality
- Ladda ner fulltext (pdf) av A Japanese translation of the Swedish Universities Scales of Personality
Ingår i Developmental Psychobiology, 2024
- DOI för The influence of anterior cingulate GABA+ and glutamate on emotion regulation and reactivity in adolescents and adults
- Ladda ner fulltext (pdf) av The influence of anterior cingulate GABA+ and glutamate on emotion regulation and reactivity in adolescents and adults
Ingår i BMC Psychiatry, 2024
- DOI för Allopregnanolone and progesterone in relation to a single electroconvulsive therapy seizure and subsequent clinical outcome: an observational cohort study
- Ladda ner fulltext (pdf) av Allopregnanolone and progesterone in relation to a single electroconvulsive therapy seizure and subsequent clinical outcome: an observational cohort study
Directed causal effect with PCMCI in hyperscanning EEG time series
Ingår i Frontiers in Neuroscience, 2024
- DOI för Directed causal effect with PCMCI in hyperscanning EEG time series
- Ladda ner fulltext (pdf) av Directed causal effect with PCMCI in hyperscanning EEG time series
Blinding integrity of dorsomedial prefrontal intermittent theta burst stimulation in depression
Ingår i International Journal of Clinical and Health Psychology, 2023
- DOI för Blinding integrity of dorsomedial prefrontal intermittent theta burst stimulation in depression
- Ladda ner fulltext (pdf) av Blinding integrity of dorsomedial prefrontal intermittent theta burst stimulation in depression
Ingår i Nordic Journal of Psychiatry, s. 312-318, 2023
- DOI för Intercorrelation of physiological seizure parameters and hormonal changes in electroconvulsive therapy
- Ladda ner fulltext (pdf) av Intercorrelation of physiological seizure parameters and hormonal changes in electroconvulsive therapy
Ingår i Translational Psychiatry, 2023
- DOI för Triple network model of brain connectivity changes related to adverse mood effects in an oral contraceptive placebo-controlled trial
- Ladda ner fulltext (pdf) av Triple network model of brain connectivity changes related to adverse mood effects in an oral contraceptive placebo-controlled trial
Dorsal anterior cingulate cortex activity during cognitive challenge in social anxiety disorder
Ingår i Behavioural Brain Research, 2023
- DOI för Dorsal anterior cingulate cortex activity during cognitive challenge in social anxiety disorder
- Ladda ner fulltext (pdf) av Dorsal anterior cingulate cortex activity during cognitive challenge in social anxiety disorder
Ingår i Behavioural Brain Research, 2023
- DOI för Pupil dilation during negative prediction errors is related to brain choline concentration and depressive symptoms in adolescents
- Ladda ner fulltext (pdf) av Pupil dilation during negative prediction errors is related to brain choline concentration and depressive symptoms in adolescents
An fMRI-study of leading and following using rhythmic tapping
Ingår i Social Neuroscience, s. 558-567, 2022
- DOI för An fMRI-study of leading and following using rhythmic tapping
- Ladda ner fulltext (pdf) av An fMRI-study of leading and following using rhythmic tapping
Ingår i NeuroImage, 2022
- DOI för Modulation of dorsolateral prefrontal cortex functional connectivity after intermittent theta-burst stimulation in depression: combining findings from fNIRS and fMRI
- Ladda ner fulltext (pdf) av Modulation of dorsolateral prefrontal cortex functional connectivity after intermittent theta-burst stimulation in depression: combining findings from fNIRS and fMRI
Ingår i Translational Psychiatry, 2022
- DOI för Serotonin and dopamine transporter availability in social anxiety disorder after combined treatment with escitalopram and cognitive-behavioral therapy
- Ladda ner fulltext (pdf) av Serotonin and dopamine transporter availability in social anxiety disorder after combined treatment with escitalopram and cognitive-behavioral therapy
Ingår i Learning and Motivation, 2022
- DOI för Internet-delivered approach-avoidance conflict task shows temporal stability and relation to trait anxiety
- Ladda ner fulltext (pdf) av Internet-delivered approach-avoidance conflict task shows temporal stability and relation to trait anxiety
Postpartum Gray Matter Changes in the Auditory Cortex
Ingår i Journal of Clinical Medicine, 2021
- DOI för Postpartum Gray Matter Changes in the Auditory Cortex
- Ladda ner fulltext (pdf) av Postpartum Gray Matter Changes in the Auditory Cortex
Ingår i Journal of Neuroscience Research, s. 2261-2270, 2021
Ingår i Frontiers in Psychiatry, 2021
- DOI för Unchanged cognitive performance and concurrent prefrontal blood oxygenation after accelerated intermittent theta-burst stimulation in depression: a sham-controlled study
- Ladda ner fulltext (pdf) av Unchanged cognitive performance and concurrent prefrontal blood oxygenation after accelerated intermittent theta-burst stimulation in depression: a sham-controlled study
Ingår i Translational Psychiatry, 2021
- DOI för Expectancy effects on serotonin and dopamine transporters during SSRI treatment of social anxiety disorder: a randomized clinical trial
- Ladda ner fulltext (pdf) av Expectancy effects on serotonin and dopamine transporters during SSRI treatment of social anxiety disorder: a randomized clinical trial
Ingår i Molecular Psychiatry, s. 3970-3979, 2021
- DOI för Expression and co-expression of serotonin and dopamine transporters in social anxiety disorder: a multitracer positron emission tomography study
- Ladda ner fulltext (pdf) av Expression and co-expression of serotonin and dopamine transporters in social anxiety disorder: a multitracer positron emission tomography study
Ingår i Diabetes, s. 1265-1277, 2021
Ingår i Psychiatry Research, 2021
- DOI för Inhibitory and excitatory neurotransmitter systems in depressed and healthy: A positron emission tomography and magnetic resonance spectroscopy study
- Ladda ner fulltext (pdf) av Inhibitory and excitatory neurotransmitter systems in depressed and healthy: A positron emission tomography and magnetic resonance spectroscopy study
Gray matter increases within subregions of the hippocampal complex after pregnancy
Ingår i Brain Imaging and Behavior, s. 2790-2794, 2021
Ingår i World Journal of Biological Psychiatry, s. 247-256, 2021
- DOI för Modulation of the prefrontal blood oxygenation response to intermittent theta-burst stimulation in depression: A sham-controlled study with functional near-infrared spectroscopy
- Ladda ner fulltext (pdf) av Modulation of the prefrontal blood oxygenation response to intermittent theta-burst stimulation in depression: A sham-controlled study with functional near-infrared spectroscopy
From baby brain to mommy brain: Widespread gray matter gain after giving birth
Ingår i Cortex, s. 334-342, 2020
Higher- and lower-order personality traits and cluster subtypes in social anxiety disorder
Ingår i PLOS ONE, 2020
- DOI för Higher- and lower-order personality traits and cluster subtypes in social anxiety disorder
- Ladda ner fulltext (pdf) av Higher- and lower-order personality traits and cluster subtypes in social anxiety disorder
Ingår i Psychiatry Research, 2020
Ingår i Journal of Affective Disorders, s. 230-237, 2020
- DOI för Neuroimaging, genetic, clinical, and demographic predictors of treatment response in patients with social anxiety disorder
- Ladda ner fulltext (pdf) av Neuroimaging, genetic, clinical, and demographic predictors of treatment response in patients with social anxiety disorder
Ingår i Brain Stimulation, s. 1665-1667, 2020
- DOI för Transcranial magnetic intermittent theta-burst stimulation for depression in pregnancy - A case series
- Ladda ner fulltext (pdf) av Transcranial magnetic intermittent theta-burst stimulation for depression in pregnancy - A case series
Ingår i Behavioural Brain Research, 2020
- DOI för Intermittent theta burst stimulation over the dorsomedial prefrontal cortex modulates resting-state connectivity in depressive patients: A sham-controlled study
- Ladda ner fulltext (pdf) av Intermittent theta burst stimulation over the dorsomedial prefrontal cortex modulates resting-state connectivity in depressive patients: A sham-controlled study
Potential Brain Age Reversal after Pregnancy: Younger Brains at 4–6 Weeks Postpartum
Ingår i Neuroscience, s. 309-314, 2018
Ingår i Neuropsychopharmacology, s. 555-563, 2018
Ingår i BJPsych bulletin, 2018
- DOI för Anterior cingulate cortex activity as a candidate biomarker for treatment selection in social anxiety disorder
- Ladda ner fulltext (pdf) av Anterior cingulate cortex activity as a candidate biomarker for treatment selection in social anxiety disorder
Emotional anticipation after delivery - a longitudinal neuroimaging study of the postpartum period
Ingår i Scientific Reports, 2017
- DOI för Emotional anticipation after delivery - a longitudinal neuroimaging study of the postpartum period
- Ladda ner fulltext (pdf) av Emotional anticipation after delivery - a longitudinal neuroimaging study of the postpartum period
Different patterns of attentional bias in antenatal and postpartum depression
Ingår i Brain and Behavior, 2017
- DOI för Different patterns of attentional bias in antenatal and postpartum depression
- Ladda ner fulltext (pdf) av Different patterns of attentional bias in antenatal and postpartum depression
Ingår i EBioMedicine, s. 179-188, 2017
- DOI för Do You Believe It? Verbal Suggestions Influence the Clinical and Neural Effects of Escitalopram in Social Anxiety Disorder: A Randomized Trial
- Ladda ner fulltext (pdf) av Do You Believe It? Verbal Suggestions Influence the Clinical and Neural Effects of Escitalopram in Social Anxiety Disorder: A Randomized Trial
Ingår i Psychiatry Research, s. 85-90, 2017
- DOI för Within-session effect of repeated stress exposure on extinction circuitry function in social anxiety disorder
- Ladda ner fulltext (pdf) av Within-session effect of repeated stress exposure on extinction circuitry function in social anxiety disorder
The effect of combined hormonal contraceptives use on brain reactivity during response inhibition
Ingår i European journal of contraception & reproductive health care, s. 150-157, 2016
Ingår i British Journal of Psychiatry, s. 229-235, 2016
Emotion Reactivity Is Increased 4-6 Weeks Postpartum in Healthy Women: A Longitudinal fMRI Study
Ingår i PLOS ONE, 2015
- DOI för Emotion Reactivity Is Increased 4-6 Weeks Postpartum in Healthy Women: A Longitudinal fMRI Study
- Ladda ner fulltext (pdf) av Emotion Reactivity Is Increased 4-6 Weeks Postpartum in Healthy Women: A Longitudinal fMRI Study
Personality and risk for postpartum depressive symptoms
Ingår i Archives of Women's Mental Health, s. 539-546, 2015
Ingår i Magnetic Resonance Materials in Physics, Biology and Medicine, 2015
Enlargement of visual processing regions in social anxiety disorder is related to symptom severity
Ingår i Neuroscience Letters, s. 114-119, 2014
Ingår i Human Brain Mapping, s. 4450-4458, 2014
Ingår i Frontiers in Neuroscience, s. 380, 2014
Ingår i Biological Psychiatry, 2014
Ingår i Biological Psychiatry, 2014
Ingår i Behavioural Brain Research, s. 330-335, 2014
Ingår i Biology of Mood & Anxiety Disorders, s. 3, 2014
Premenstrual dysphoric disorder and prefrontal reactivity during anticipation of emotional stimuli
Ingår i European Neuropsychopharmacology, s. 1474-1483, 2013
Ingår i Biological Psychiatry, 2013
Altered Amygdala but not Default Mode Network Functional Connectivity in Social Anxiety Disorder
Ingår i Biological Psychiatry, 2013
Ingår i Biological Psychiatry, 2013
Ingår i Biological Psychiatry, 2013
Ingår i Psychoneuroendocrinology, s. 1133-1144, 2013
Prefrontal activity during response inhibition decreases over time in the postpartum period
Ingår i Behavioural Brain Research, s. 132-138, 2013
Acute Sleep Deprivation Enhances the Brain's Response to Hedonic Food Stimuli: An fMRI Study
Ingår i Journal of Clinical Endocrinology and Metabolism, 2012
Ingår i Journal of Affective Disorders, s. 347-350, 2012
Ingår i Hormones and Behavior, s. 400-406, 2012
Ingår i Gynecological Endocrinology, s. 486-490, 2011
Ingår i Archives of Women's Mental Health, s. 417-423, 2010
Ingår i Biological Psychiatry, s. 124, 2009
Artiklar, forskningsöversikt
Ingår i Psychoneuroendocrinology, s. 28-52, 2014