Siv Jönsson

Jag är affilierad till Farmakometrigruppen, som arbetar med ’non-linear mixed effects models’ dvs matematiska modeller som beskriver hur koncentrationer och effekter av läkemedel förändras över tid samt varierar mellan individer. Modellerna används vid optimering av såväl användning som utveckling av läkemedel.

Jag arbetar med Mats Karlsson Elisabet Nielsen och Lena Friberg i projekt inom modell-baserad individualiserad behandling, immunologi and onkologi.

Dr Siv Jönsson was a senior researcher in the Pharmacometric group within the Department of Pharmacy, Uppsala University, Sweden, headed by Professor Mats O Karlsson, up until end of 2023. Siv earned an MSc degree in 1988 and has thereafter been working in the pharmacokinetic, pharmacodynamic and pharmacometric areas in three environments: the pharmaceutical industry, the regulatory agency, in academia and in pharmacometric consultancy.

In total 5 years were spent within industry (Kabi Pharmacia, Astra Zeneca) working with clinical pharmacology and pharmacometrics. Furthermore, Siv worked as a pharmacokinetic assessor within the Swedish regulatory authority (Medical Products Agency) in 2 periods (in total 9 years, latest period 2007-2011). Finally, the academic years include her PhD education (PhD obtained in 2004), 2 years as senior lecturer and 12 years as researcher; all these years dealing with methodological and applied pharmacometric projects, where applied projects relate to e.g. renal transplant patients and haemophilia A/B patients. Since 2019, Siv is an employee of Pharmetheus AB, Uppsala, Sweden, but keeps an affiliation with the Pharmacometrics group.

Siv has published approximately 50 peer-reviewed research articles and book chapters and is currently the co-supervisor of 4 PhD students.