Syllabus for Pharmaceutical Bioinformatics with Sequence Analysis

Farmaceutisk bioinformatik med sekvensanalys

  • 7.5 credits
  • Course code: 3FF276
  • Education cycle: Second cycle
  • Main field(s) of study and in-depth level: Pharmaceutical Sciences A1N, Drug Discovery and Development A1N

    Main field(s) of study and in-depth level

    The code indicates the education cycle and in-depth level of the course in relation to other courses within the same main field of study according to the requirements for general degrees:

    First cycle
    G1N: has only upper-secondary level entry requirements
    G1F: has less than 60 credits in first-cycle course/s as entry requirements
    G1E: contains specially designed degree project for Higher Education Diploma
    G2F: has at least 60 credits in first-cycle course/s as entry requirements
    G2E: has at least 60 credits in first-cycle course/s as entry requirements, contains degree project for Bachelor of Arts/Bachelor of Science
    GXX: in-depth level of the course cannot be classified.

    Second cycle
    A1N: has only first-cycle course/s as entry requirements
    A1F: has second-cycle course/s as entry requirements
    A1E: contains degree project for Master of Arts/Master of Science (60 credits)
    A2E: contains degree project for Master of Arts/Master of Science (120 credits)
    AXX: in-depth level of the course cannot be classified.

  • Grading system: Fail (U), Pass (G), Pass with distinction (VG)
  • Established: 2016-05-26
  • Established by:
  • Revised: 2019-04-25
  • Revised by: The Educational Board of Pharmacy
  • Applies from: week 32, 2019
  • Entry requirements: Admitted to Master Program in Pharmaceutical Modelling and completed previous courses.
    Within the Master of Science in Pharmacy Programme, it is required that the student has at least 150 credits and completed semester 1-7.
    Within the civil engineering programs chemical engineering, molecular biotechnology, and bioinformatics required are at least 120 credits, of which 30 within bioscience.
    For non-programme students a Bachelor of Pharmaceutical Science/ Science in Pharmacy, or equal degree is required (180 credits). Knowledge in English equivalent to that required for basic eligibility to Swedish higher education.
  • Responsible department: Department of Pharmaceutical Biosciences

Decisions and guidelines

The course can not be combined with Pharmaceutical bioinformatics 3FF575 or 8FF575, due to overlap in course contents.
This course substitutes and corresponds to 3FF576.

Learning outcomes

After having completed the course, the students should be able to:

  • describe bioinformatics tools and methods and how they can be used within pharmaceutical research
  • use bio- and cheminformatics programs for e.g. sequence analysis, expression analysis,  functional predictions, 3D-visualisation, and structure-activity relationship based methods
  • locate relevant information in biological and chemical databases
  • train, validate and use predictive models based on biochemical data
  • describe and carry out basic sequence analysis tasks
  • calculate numerical representations of chemical structures, and correlate these to target protein interactionsinterpret and validate results of above-mentioned methods.

Content

The course contains theory and methods for bioinformatics analysis and the basics of how bioinformatics can be used within the pharmacutical area. The course presents introduction and historical account of pharmaceutical bioinformatics, representation of biological and chemical data in computers, biological and chemical databases, theory and methods for analysis of experimental data, sequence analysis, expression analysis, predictive modelling, mode! validation, design of experiments, structure-activity relationships, and applications in pharmaceutical  bioinformatics. For computationally demanding analysis high performance computing resources will be used.

Instruction

Teaching is in the form of lecture and computer exercises. Compulsory parts: computer exercises and assignments. The course may be given in English.

Assessment

Passed course demands a passed written individual examination and passed compulsory parts. Completion of compulsory parts of the course may be done earliest at next course instance, if space permits.If there are special reasons for doing so, an examiner may make an exception from the method of assessment indicated and allow a student to be assessed by another method. An example of special reasons might be a certificate regarding special pedagogical support from the University´s disability coordinator.

Reading list

The reading list is missing. For further information, please contact the responsible department.