Nuclide Diagnostics and Therapy

12 credits

Syllabus, Master's level, 3DR405

Code
3DR405
Education cycle
Second cycle
Main field(s) of study and in-depth level
Medical Nuclide Techniques A1F
Grading system
Fail (U), Pass (G)
Finalised by
The Master Programmes Board of the Faculty of Medicine, 12 April 2018
Responsible department
Department of Immunology, Genetics and Pathology

Entry requirements

A Bachelor's degree, equivalent to a Swedish Kandidatexamen, from an internationally recognised university in life sciences (e.g. physics, radiophysics, chemistry or biology), medicine, pharmacy, nursing, or other relevant university education. Radiation Protection and Medical Effects, 6 credits, Nuclide Production and Radiochemistry, 9 credits, and Detection Techniques and Dosimetry, 12 credits.

Learning outcomes

On completion of the course, the student should

  • describe and explain the principles of radionuclide-based pharmacokinetics, diagnostics and imaging for analysis of experimental research and for clinical analysis of disease
  • understand and be able to explain the knowledge that is gained with radionuclide-based pharmacokinetics, diagnostics and imaging
  • analyse and interpret results from radionuclide based investigations
  • describe how to design radionuclide-based pharmacokinetics, diagnostics and imaging as support for surgery
  • describe and explain the principles of radionuclide-based therapy of tumours
  • understand how radiation doses are calculated in radionuclide-based therapy of tumours.

In addition the student should demonstrate an understanding of a scientific approach, how to evaluate scientific

investigations, how ethical considerations are applied on research and how scientific results are communicated.

Content

  • Analysis of pharmacokinetics and compound biodistribution
  • Molecular imaging in physiology, pharmacology and oncology
  • Cardiology (perfusion, viability, function)
  • Neurology and radiolabelled tracers for neuropharmacology
  • Radionuclide based diagnostics and imaging as support for treatment of patients
  • Radiolabelled tracers and development of new drugs
  • Developmental trends in diagnostics and imaging
  • Radioactive nuclides for diagnostics and therapy
  • Tumours suitable for treatment with nuclides
  • Targeting principles: tumour targets and targeting agents
  • Pharmacokinetics and cellular processing of targeting agents
  • Radionuclide therapy in clinics: well-tried methods and new ideas

Instruction

The teaching is given as lectures, seminars, laborations and project work. Special focus is directed to stimulate the students to independently solve problems.

Compulsory parts of the course: All parts in connection with seminars, laboratory sessions and project work.

Assessment

Written examination, seminars (oral and written presentation), laborations (oral and written presentation) and project work (oral and written presentation). For a pass on the course, passed examination, passed seminars, passed laborations and passed project work are required.

If there are special reasons for doing so, an examiner may make an exception from the method of assessment indicated and allow a student to be assessed by another method. An example of special reasons might be a certificate regarding special pedagogical support from the University's disability coordinator.

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