New type of drug candidate effectively accelerates wound healing in clinical study
30 maj 2023
Complicated, hard-to-heal wounds are a growing medical problem and there are currently only two drugs approved with proven efficacy. In a new study on humans, researchers at Uppsala University show that treatment with a specific type of modified lactic acid bacteria works well and has a positive effect on the healing of wounds.
Junk food may impair our deep sleep
30 maj 2023
In a new study, researchers at Uppsala University have investigated how junk food affects sleep. Healthy participants consumed an unhealthier as well as a healthier diet in a randomised order. After the unhealthier diet, the quality of the participants’ deep sleep had deteriorated, compared with those who had followed the healthier diet. The results have been published in the journal Obesity.
Barren habitat for sows leaves imprint on piglets’ brains
26 maj 2023
In a new study, researchers from Uppsala University in Sweden, together with colleagues from the University of São Paulo, Brazil, have investigated the impact that a barren living environment for sows leaves on the next generation. The pigs in the study were bred in Brazil and kept according to breeding standards in that country. The sows’ uncomfortable and unstimulating environment brought with it several different types of changes in the epi...
Alexander Wendt and Martha Finnemore awarded the Johan Skytte Prize in Political Science
25 maj 2023
The Johan Skytte Foundation is delighted to announce that Alexander Wendt and Martha Finnemore have been jointly awarded the Johan Skytte Prize in Political Science. The prize is a recognition of their exceptional contributions to the field, particularly in advancing the constructivist approach to the study of international relations.
Aviation fuel directly from carbon dioxide, water and sunlight
25 maj 2023
In the quest for fossil-free fuels for aircraft, a new study shows that isoprene could be part of a future solution. Isoprene can be produced by blue-green algae from sunlight, water and ordinary carbon dioxide. The productivity of the cyanobacteria increases if they are exposed to violet light or higher temperatures, and isoprene is ideally suited for photochemical processing into aviation fuels.
New therapy helps immune system eradicate brain tumours
11 maj 2023
Researchers from Uppsala University have developed a method that helps immune cells exit from blood vessels into the tumour and kill cancer cells. The aim is to improve treatment of aggressive brain tumours. The study has been published in the journal Cancer Cell.
Hijacking strategy mapped for hundreds of viruses
28 april 2023
One strategy that viruses use to take over a host cell is to mimic small parts of the cell's proteins called motifs. In a new study coordinated from Uppsala University, researchers have used a new method and doubled the available information on how viruses mimic human binding motifs. The results suggest new targets for the development of antiviral inhibitors.
Genomes from 240 mammal species explain human disease risks
27 april 2023
Why is it that certain mammals have an exceptional sense of smell, some hibernate, and yet others, including humans, are predisposed to disease? A major international research project, jointly led by Uppsala University, Sweden and the Broad Institute, USA, has surveyed and analysed the genomes of 240 different mammals. The results, now published in 11 articles in the journal Science, show how the genomes of humans and other mammals have develo...
Increased risk of testicular cancer in people with neurodevelopmental disorders
24 april 2023
A new study by researchers at Uppsala University and Uppsala University Hospital shows that men who have a neurodevelopmental disorder, such as autism and ADHD, also have a slightly increased risk of testicular cancer, or seminoma. This is the first study to show such a link, with the results to be published in the British Journal of Cancer.
Wide income gaps lead to higher mortality rates during flood disasters
18 april 2023
A new study led by researchers from Uppsala University shows a clear link between economic inequality and mortality during severe flood disasters. Countries with an uneven distribution of income had many times higher mortality rates compared to countries with more evenly distributed income levels. The results are published in the scientific journal Nature Sustainability.
Personalised blood pressure treatment more effective
11 april 2023
Patients treated with blood pressure-lowering drugs can experience much greater improvements from a change of medication than from doubling the dose of their current medication. This is shown by a new study from Uppsala University, published in the Journal of the American Medical Association (JAMA). In this study, 280 patients tested four different blood pressure-lowering drugs over the course of a year.
Swimming pools of the rich make cities thirsty
11 april 2023
Rich elites with large swimming pools and well-maintained lawns are leaving poorer communities without basic access to water in cities across the world. New research, led by Uppsala University, published in Nature Sustainability has found social inequalities are driving urban water crises more than environmental factors, such as climate change or the growth of urban populations.
One of Vasa’s crewmen was a woman
04 april 2023
When the human remains found on board the warship Vasa were investigated, it was determined that the skeleton designated G was a man. New research now shows that the skeleton is actually from a woman.
Atmospheric circulation patterns contribute to extreme weather events
31 mars 2023
The sharp increase in heatwaves in southern Europe in recent years is not only due to the greenhouse effect. Climate change has made a particular type of atmospheric circulation pattern more common, and this has contributed to extreme weather and been the underlying cause of nine out of ten heat-related deaths. This is according to a new study by researchers from Uppsala University and CNRS in France.
Autism may be linked to different perceptions of movement in infancy
30 mars 2023
A new study from researchers at Uppsala University and Karolinska Institutet shows that children who go on to develop symptoms of autism have different activity in their brain's visual cortex from as early as five months when looking at certain types of movement. This finding may indicate that autistic people perceive their surroundings in a different way even from a very young age, which could affect their development and learning.
From living heritage to zombie churches
22 mars 2023
Churches are preserved by an antiquarian system that risks killing them instead of keeping them alive. The Swedish State and the Church of Sweden therefore need to define new joint visions and goals to enable the ecclesiastical cultural heritage to be used and developed. This is shown by historian of art Henrik Lindblad in a new doctoral thesis from Uppsala University.
Uppsala scientists reveal protein synthesis mechanism in Giardia
17 mars 2023
Scientists from Uppsala University have used cryo-electron microscopy to reveal details of the protein synthesis mechanism in the parasite Giardia intestinalis, which causes diarrhoeal disease. The new insights could be valuable for screening specific drugs against Giardia and other protozoan parasites.
Oldest sea reptile from Age of Dinosaurs found on Arctic island
13 mars 2023
For nearly 190 years, scientists have searched for the origins of ancient sea-going reptiles from the Age of Dinosaurs. Now a team of Swedish and Norwegian palaeontologists has discovered remains of the earliest known ichthyosaur or ‘fish-lizard’ on the remote Arctic island of Spitsbergen.
Large donation for research into the human immune system
09 mars 2023
Thanks to a gift from an American donor to Uppsala University, Sweden, research into immune reactions in cases of transplantation, autoimmunity and cancer will receive a major boost. The donation, totalling USD 4.5 million, will increase opportunities to develop new treatment strategies in this vital area over the long term.
Overweight in children increased during the pandemic
08 mars 2023
Overweight and obesity among four-year-olds increased during the COVID-19 pandemic, according to a new study by Uppsala University involving over 200,000 children in Sweden. The number of children with obesity increased by some 30 percent, and there are large regional differences. The study was published in the journal Acta Paediatrica.
“You throw up, then you cough, then you feel better or die”
02 mars 2023
Detailed images of illness, death and cancelled activities; these were some of the common themes of children’s drawings during the COVID-19 pandemic. A new study from Uppsala University, in which researchers studied 91 drawings made by children aged between 4 and 6, shows that the pandemic affected the children significantly and that they had extensive knowledge about the disease.
New artificial model validates antibodies ability to reach the brain
24 februari 2023
A research group at Uppsala University has developed a simple and effective artificial blood-brain barrier model that can be used to determine how well antibody-based therapies can enter the brain. Today animal experimentation is the most common method for testing an antibody’s function and the new model could reduce the need for animal testing.
Press invitation: Dag Hammarskjöld Lecture with Amina J. Mohammed
15 februari 2023
On 23 February the Deputy Secretary-General of the United Nations, Amina J Mohammed, will give the Dag Hammarskjöld lecture in Uppsala. The lecture is open to the public.
Antibiotics hindered treatment of urinary tract bacteria during the pandemic
14 februari 2023
The use of broad-spectrum antibiotics increased drastically in intensive care at the beginning of the Covid-19 pandemic. At first, this helped patients avoid urinary tract infections and seemed to prevent the growth of most bacteria. However, it also contributed to a sharp growth in enterococci, an antibiotic-tolerant group of bacteria, which rendered the treatment of urinary tract infections more difficult.
Combination of immune cells could provide clearer prognoses for cancer
08 februari 2023
Thanks to a new prognostic method for detecting cancers including cancer of the large intestine, doctors could provide clearer disease prognoses and predict which patients will respond best to immunotherapy. The method consists of a combination of two types of immune cells that characterise certain forms of cancer. This has been shown in a new study by researchers at Uppsala University to be published in the journal eBioMedicine.
Early tastings shorten breastfeeding
18 januari 2023
The earlier infants begin to taste small samples of solid food, the earlier they eat more food and stop breastfeeding. This is shown in a new study from Uppsala University and Sophiahemmet University, in which the mothers of 1,251 infants from all over Sweden participated. Almost half of the infants received tastings at the age of four months.
Perseverant bacteria challenge antibacterial treatment
04 januari 2023
Bacterial perseverance is a new phenomenon that helps explain how bacteria adapt to survive antibiotic treatments. A group of researchers at Uppsala University have studied how individual bacteria react when exposed to different antibiotics. The result underlines the importance of adhering strictly to antibiotic prescriptions.
How fat takes over the lymph nodes as we age
21 december 2022
A new study from researchers at Uppsala University presents novel findings on why human lymph nodes lose their function with age and the consequences for the effectiveness of our immune system. The article has been published in The Journal of Pathology.
Scandinavian wolves carry many harmful mutations
14 december 2022
In a new scientific study, researchers at Uppsala University have shown that Scandinavian wolves carry around 100,000 harmful mutations in their genome. As long as the harmful mutations can be compensated by a healthy genetic variant, this does not need to pose a problem. However, as there has been a high level of inbreeding in the wolf population, the occurrence of double harmful variants has increased with each generation.
Y chromosome loss may be linked to men's increased risk of severe COVID-19
14 december 2022
Men are at an increased risk of a severe bout of COVID-19 compared to women. Researchers at Uppsala University have now shown that this may be due to loss of the Y chromosome in part of their white blood cells. The findings could eventually be used to assess the risk of developing severe COVID-19 and perhaps to improve treatment.
Atopic dermatitis in dogs linked to certain parts of the genome
09 december 2022
Using new gene mapping methods, researchers have found connections between atopic dermatitis (eczema) in dogs and several regions of the genome. Some of the genes identified coincide with genes linked to similar problems in humans. The filaggrin gene region, for example, which is regarded as the most powerful risk factor for atopic eczema in humans, has now also been linked to this disease in Labrador retrievers.
DNA sequence enhances understanding origins of jaws
25 november 2022
Researchers at Uppsala University have discovered and characterised a DNA sequence found in jawed vertebrates, such as sharks and humans, but absent in jawless vertebrates, such as lampreys. This DNA is important for the shaping of the joint surfaces during embryo development.
Old World flycatchers’ family tree mapped
23 november 2022
The European robin’s closest relatives are found in tropical Africa. The European robin is therefore not closely related to the Japanese robin, despite their close similarity in appearance. This is confirmed by a new study of the Old World flycatcher family, to which these birds belong. The study comprises 92 per cent of the more than 300 species in this family.
Tablet computers make preschool children’s play less creative
21 november 2022
Preschool children's play involving tablets is less creative and imaginative compared to their play involving physical toys. This is shown in a new study by Uppsala University, and the difference is substantial. The results counter occasional claims that new technology would make children more creative.
Safe surgical access to the central core of the human cochlea verified
08 november 2022
An international team of surgeons and scientists from, among others, Uppsala University has confirmed secure surgical access to the central core of the human cochlea. The research, published today in Scientific Reports, is critical to the first in-human trials of new cell, gene and drug therapies for the inner ear, and will assist with treatment for improving hearing loss and deafness over the long-term.
A stem cell protein facilitates relapse of pediatric brain tumours
28 oktober 2022
The malignant brain tumour type medulloblastoma can become resistant to therapy which can cause relapse. Researchers at Uppsala University have discovered a certain protein that makes tumour cells resting and insensitive to radiation treatment. The research group hopes that the results could eventually lead to better treatments for children that have the highest risk to develop relapses.
Healthy food systems in focus at Uppsala Health Summit
19 oktober 2022
Food lies at the heart of both health and sustainable development. This year’s Uppsala Health Summit takes on the challenges associated with our food systems and how to make them healthier, more inclusive, equitable and sustainable.
SSRIs and CBT lead to changes in the brain
18 oktober 2022
Neurochemical changes in the brain differ among patients with social anxiety treated using both SSRIs and CBT, compared to those treated using only CBT. While the combined treatment involving the medicine blocked the serotonin transporters, availability of such transporters increased in patients who only received CBT.
Widespread variation of inherited retroviruses among Darwin’s finches
13 oktober 2022
Vertebrate genomes are repositories for retrovirus code that was deposited into germ line as inherited endogenous retroviruses during evolution. Researchers from Uppsala University and Princeton University now provide new findings about retroviral establishment and distribution among Darwin’s finches. The findings are being published in Nature Communications.
PRESS INVITATION: Inauguration of the Alva Myrdal Centre for Nuclear Disarmament
12 oktober 2022
The current nuclear threat is the most serious since the end of the Cold War. How did we get here and what role can the new Alva Myrdal Centre for Nuclear Disarmament play? On 19 October, Uppsala University will inaugurate this highly relevant centre. Speakers at the inauguration include Beatrice Fihn, Executive Director of the International Campaign to Abolish Nuclear Weapons (ICAN), recipient of the Nobel Peace Prize in 2017, and Rupal N. Me...
The vulnerability of surrogate mothers in a global market
11 oktober 2022
A new dissertation on surrogacy highlights Thai women's experiences of having acted as surrogate mothers. The dissertation shows the women's vulnerability in a global surrogacy industry, but also provides a more nuanced picture of what makes women seek surrogacy and how they relate to the process.
Widespread metabolic dysregulation in different organs in type 2 diabetes
07 oktober 2022
Using state of the art techniques, researchers from Uppsala University have shown that the metabolism in patients with type 2 diabetes and prediabetes was much more disturbed than previously known, and that it varied between organs and with the severity of the disease. The study, which is a collaboration with Copenhagen University and AstraZeneca, among others, has been published in the journal Cell Reports Medicine.
Weighted blanket increases melatonin
03 oktober 2022
A new study from Uppsala University shows that using a weighted blanket at bedtime increases melatonin in young adults. This hormone increases in response to darkness, and some evidence suggests that it promotes sleep. The findings are published in the Journal of Sleep Research.
400 years of political science in Uppsala
30 september 2022
On 1 October this year, it will be 400 years since Johan Skytte founded a professorship in eloquence and political science. His intention was to strengthen the state administration by providing the highly qualified diplomats and civil servants that Sweden needed to maintain its position as a European great power. The Johan Skytte Professorship is the oldest active chair in political science in the world. To mark the 400th anniversary, a lectur...
Higher temperatures make it difficult for fig tree pollinators
23 september 2022
Researchers from Uppsala University and elsewhere have been studying the effect of rising temperatures on the lifespan of pollinating fig wasps. The findings show that the wasps lived much shorter lives at high temperatures, which would make it difficult for them to travel the long distances between the trees they pollinate.
Strong link between gut bacteria and metabolites
23 september 2022
There are strong links between bacteria living in the gut and the levels of small molecules in the blood known as metabolites. Such is the finding of a new study led by researchers from Uppsala University and Lund University, which is now published in the journal Nature Communications.
Hjärnäpplet award goes to Johan Elf and Özden Baltekin
08 september 2022
In just 30 minutes, their test can determine which antibiotic is required to treat a urinary tract infection. Johan Elf and Özden Baltekin are recognised for their innovation, which will help reduce antibiotic resistance and advance personalised care.
Genetic background associated with physically active lifestyle
07 september 2022
In a large international study, researchers at Uppsala University have identified DNA regions that are associated with physical activity or leisure screen time. The findings confirm that physical activity is beneficial for health and suggest that a more sedentary lifestyle can be explained by how muscles respond to exercise.
The University to hand over human remains to Arjeplog’s Sami association
07 september 2022
Uppsala University is now handing over the remains of a man contained in the University’s collections to Arjeplog’s Sami association. He will be interred at a ceremony in Arjeplog on 9 September, along with other remains contained in Lund University’s collections.
New model forecasts birth dates
06 september 2022
Since its launch in October last year, the Pregspect website has been used by approximately 18,000 pregnant women. Mikael Elinder, associate professor at the Department of Economics, is one of the researchers behind the service, which calculates personalised birth forecasts.