Tatjana Pandzic

Precision Diagnostics in Myeloid Malignancies: Development and Validation of a National Capture‐Based Gene Panel

Orsmark‐Pietras, Christina; Lyander, Anna; Ladenvall, Claes; Hallström, Björn et al.

Part of Genes, Chromosomes and Cancer, 2024

• DOI for Precision Diagnostics in Myeloid Malignancies: Development and Validation of a National Capture‐Based Gene Panel
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Cancer associated variant enrichment CAVE, a gene agnostic approach to identify low burden variants in chronic lymphocytic leukemia

Yaacov, Adar; Lazarian, Gregory; Pandzic, Tatjana; Weström, Simone et al.

Part of Scientific Reports, 2024

• DOI for Cancer associated variant enrichment CAVE, a gene agnostic approach to identify low burden variants in chronic lymphocytic leukemia
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Pathogenic DDX41 variants, possible response predictors to low-dose melphalan in hypo- and normocellular MDS and AML

Nyquist, Otto Emil; Dalgaard, Jakob; Spetalen, Signe; Torkildsen, Synne et al.

Part of British Journal of Haematology, p. 724-729, 2024

• DOI for Pathogenic DDX41 variants, possible response predictors to low-dose melphalan in hypo- and normocellular MDS and AML

Micro-costing of genetic diagnostics in acute leukemia in Sweden: from standard-of-care to whole-genome sequencing

Thangavelu, Tharshini; Wirta, Valtteri; Orsmark-Pietras, Christina; Cavelier, Lucia et al.

Part of Journal of Medical Economics, p. 1053-1060, 2024

• DOI for Micro-costing of genetic diagnostics in acute leukemia in Sweden: from standard-of-care to whole-genome sequencing
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Patient-Specific Measurable Residual Disease Markers Predict Outcome in Patients With Myelodysplastic Syndrome and Related Diseases After Hematopoietic Stem-Cell Transplantation

Tobiasson, Magnus; Pandzic, Tatjana; Illman, Johanna; Nilsson, Lars et al.

Part of Journal of Clinical Oncology, 2024

• DOI for Patient-Specific Measurable Residual Disease Markers Predict Outcome in Patients With Myelodysplastic Syndrome and Related Diseases After Hematopoietic Stem-Cell Transplantation

Precision Diagnostics in Myeloid Malignancies: Development and Validation of a National Capture‐Based Gene Panel

Orsmark‐Pietras, Christina; Lyander, Anna; Ladenvall, Claes; Hallström, Björn et al.

Part of Genes, Chromosomes and Cancer, 2024

• DOI for Precision Diagnostics in Myeloid Malignancies: Development and Validation of a National Capture‐Based Gene Panel
• Download full text (pdf) of Precision Diagnostics in Myeloid Malignancies: Development and Validation of a National Capture‐Based Gene Panel

Cancer associated variant enrichment CAVE, a gene agnostic approach to identify low burden variants in chronic lymphocytic leukemia

Yaacov, Adar; Lazarian, Gregory; Pandzic, Tatjana; Weström, Simone et al.

Part of Scientific Reports, 2024

• DOI for Cancer associated variant enrichment CAVE, a gene agnostic approach to identify low burden variants in chronic lymphocytic leukemia
• Download full text (pdf) of Cancer associated variant enrichment CAVE, a gene agnostic approach to identify low burden variants in chronic lymphocytic leukemia

Pathogenic DDX41 variants, possible response predictors to low-dose melphalan in hypo- and normocellular MDS and AML

Nyquist, Otto Emil; Dalgaard, Jakob; Spetalen, Signe; Torkildsen, Synne et al.

Part of British Journal of Haematology, p. 724-729, 2024

• DOI for Pathogenic DDX41 variants, possible response predictors to low-dose melphalan in hypo- and normocellular MDS and AML

Micro-costing of genetic diagnostics in acute leukemia in Sweden: from standard-of-care to whole-genome sequencing

Thangavelu, Tharshini; Wirta, Valtteri; Orsmark-Pietras, Christina; Cavelier, Lucia et al.

Part of Journal of Medical Economics, p. 1053-1060, 2024

• DOI for Micro-costing of genetic diagnostics in acute leukemia in Sweden: from standard-of-care to whole-genome sequencing
• Download full text (pdf) of Micro-costing of genetic diagnostics in acute leukemia in Sweden: from standard-of-care to whole-genome sequencing

Patient-Specific Measurable Residual Disease Markers Predict Outcome in Patients With Myelodysplastic Syndrome and Related Diseases After Hematopoietic Stem-Cell Transplantation

Tobiasson, Magnus; Pandzic, Tatjana; Illman, Johanna; Nilsson, Lars et al.

Part of Journal of Clinical Oncology, 2024

• DOI for Patient-Specific Measurable Residual Disease Markers Predict Outcome in Patients With Myelodysplastic Syndrome and Related Diseases After Hematopoietic Stem-Cell Transplantation

BTK and PLCG2 remain unmutated in one-third of patients with CLL relapsing on ibrutinib

Bonfiglio, Silvia; Sutton, Lesley-Ann; Ljungström, Viktor; Capasso, Antonella et al.

Part of Blood Advances, p. 2794-2806, 2023

• DOI for BTK and PLCG2 remain unmutated in one-third of patients with CLL relapsing on ibrutinib
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Loss of Y and clonal hematopoiesis in blood: two sides of the same coin?

Ljungström, Viktor; Mattisson, Jonas; Halvardson, Jonatan; Pandzic, Tatjana et al.

Part of Leukemia, p. 889-891, 2022

• DOI for Loss of Y and clonal hematopoiesis in blood: two sides of the same coin?
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Clonal haematopoiesis as a risk factor for therapy-related myeloid neoplasms in patients with chronic lymphocytic leukaemia treated with chemo-(immuno)therapy

Voso, Maria-Teresa; Pandzic, Tatjana; Falconi, Giulia; Dencic-Fekete, Marija et al.

Part of British Journal of Haematology, p. 103-113, 2022

• DOI for Clonal haematopoiesis as a risk factor for therapy-related myeloid neoplasms in patients with chronic lymphocytic leukaemia treated with chemo-(immuno)therapy

Familial platelet disorder due to germline exonic deletions in RUNX1: a diagnostic challenge with distinct alterations of the transcript isoform equilibrium

Engvall, Marie; Karlsson, Ylva; Kuchinskaya, Ekaterina; Jörnegren, Åsa et al.

Part of Leukemia and Lymphoma, p. 2311-2320, 2022

• DOI for Familial platelet disorder due to germline exonic deletions in RUNX1: a diagnostic challenge with distinct alterations of the transcript isoform equilibrium
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Five Percent Variant Allele Frequency Is a Reliable Reporting Threshold for TP53 Variants Detected by Next Generation Sequencing in Chronic Lymphocytic Leukemia in the Clinical Setting

Pandzic, Tatjana; Ladenvall, Claes; Engvall, Marie; Mattsson, Mattias et al.

Part of HemaSphere, 2022

• DOI for Five Percent Variant Allele Frequency Is a Reliable Reporting Threshold for TP53 Variants Detected by Next Generation Sequencing in Chronic Lymphocytic Leukemia in the Clinical Setting
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Comparative analysis of targeted next-generation sequencing panels for the detection of gene mutations in chronic lymphocytic leukemia: an ERIC multi-center study

Sutton, Lesley-Ann; Ljungström, Viktor; Enjuanes, Anna; Cortese, Diego et al.

Part of Haematologica, p. 682-691, 2021

• DOI for Comparative analysis of targeted next-generation sequencing panels for the detection of gene mutations in chronic lymphocytic leukemia: an ERIC multi-center study
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Cell-of-origin determined by both gene expression profiling and immunohistochemistry is the strongest predictor of survival in patients with diffuse large B-cell lymphoma

Abdulla, Maysaa; Hollander, Peter; Pandzic, Tatjana; Mansouri, Larry et al.

Part of American Journal of Hematology, p. 57-67, 2020

• DOI for Cell-of-origin determined by both gene expression profiling and immunohistochemistry is the strongest predictor of survival in patients with diffuse large B-cell lymphoma
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Clonal hematopoiesis in patients with high-grade B-cell lymphoma is associated with inferior outcome

Amini, Rose-Marie; Ljungström, Viktor; Abdulla, Maysaa; Cavelier, Lucia et al.

Part of American Journal of Hematology, 2020

• DOI for Clonal hematopoiesis in patients with high-grade B-cell lymphoma is associated with inferior outcome
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Restoration of KMT2C/MLL3 in human colorectal cancer cells reinforces genome-wide H3K4me1 profiles and influences cell growth and gene expression

Larsson, Chatarina; Cordeddu, Lina; Siggens, Lee; Djureinovic, Tatjana et al.

Part of Clinical Epigenetics, 2020

• DOI for Restoration of KMT2C/MLL3 in human colorectal cancer cells reinforces genome-wide H3K4me1 profiles and influences cell growth and gene expression
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Angioimmunoblastic T-cell lymphoma and myelodysplastic syndrome with mutations in TET2, DNMT3 and CUX1: azacitidine induces only lymphoma remission

Tobiasson, Magnus; Pandzic, Tatjana; Cavelier, Lucia; Sander, Birgitta et al.

Part of Leukemia and Lymphoma, p. 3316-3319, 2019

• DOI for Angioimmunoblastic T-cell lymphoma and myelodysplastic syndrome with mutations in TET2, DNMT3 and CUX1: azacitidine induces only lymphoma remission

Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations

Agathangelidis, Andreas; Ljungström, Viktor; Scarfo, Lydia; Fazi, Claudia et al.

Part of Haematologica, p. 865-873, 2018

• DOI for Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations
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Loss of DIP2C in RKO cells stimulates changes in DNA methylation and epithelial-mesenchymal transition

Larsson, Chatarina; Ali, Muhammad Akhtar; Djureinovic, Tatjana; Lindroth, Anders M. et al.

Part of BMC Cancer, 2017

• DOI for Loss of DIP2C in RKO cells stimulates changes in DNA methylation and epithelial-mesenchymal transition
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Somatic PRDM2 c.4467delA mutations in colorectal cancers control histone methylation and tumor growth

Pandzic, Tatjana; Rendo, Verónica; Lim, Jinyeong; Larsson, Chatarina et al.

Part of Oncotarget, p. 98646-98659, 2017

• DOI for Somatic PRDM2 c.4467delA mutations in colorectal cancers control histone methylation and tumor growth

Mechanistic characterization of a copper containing thiosemicarbazone with potent antitumor activity

Karlsson, Henning; Fryknäs, Mårten; Strese, Sara; Gullbo, Joachim et al.

Part of Oncotarget, p. 30217-30234, 2017

• DOI for Mechanistic characterization of a copper containing thiosemicarbazone with potent antitumor activity
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Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma

Mansouri, Larry; Noerenberg, Daniel; Young, Emma; Mylonas, Elena et al.

Part of Blood, p. 2666-2670, 2016

• DOI for Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma

Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations

Ljungström, Viktor; Cortese, Diego; Young, Emma; Pandzic, Tatjana et al.

Part of Blood, p. 1007-1016, 2016

• DOI for Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations

Transposon Mutagenesis Reveals Fludarabine Resistance Mechanisms in Chronic Lymphocytic Leukemia

Pandzic, Tatjana; Larsson, Jimmy; He, Liqun; Kundu, Snehangshu et al.

Part of Clinical Cancer Research, p. 6217-6227, 2016

• DOI for Transposon Mutagenesis Reveals Fludarabine Resistance Mechanisms in Chronic Lymphocytic Leukemia

DISSECTING RESISTANCE MECHANISMS IN CHRONIC LYMPHOCYTIC LEUKEMIA USING WHOLE-EXOME SEQUENCING: IMPACT OF RECURRENT RPS15 MUTATIONS ON P53 DYSREGULATION

Ljungström, Viktor; Cortese, Diego; Young, Emma; Pandzic, Tatjana et al.

Part of Haematologica, p. 10-11, 2015

Computational and molecular tools for scalable rAAV-mediated genome editing

Stoimenov, Ivaylo; Ali, Muhammad Akhtar; Pandzic, Tatjana; Sjöblom, Tobias

Part of Nucleic Acids Research, 2015

• DOI for Computational and molecular tools for scalable rAAV-mediated genome editing

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Gad, Helge; Koolmeister, Tobias; Jemth, Ann-Sofie; Eshtad, Saeed et al.

Part of Nature, p. 215-221, 2014

• DOI for MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Gene rearrangements in hormone receptor negative breast cancers revealed by mate pair sequencing

Jiao, Xiang; Hooper, Sean D.; Djureinovic, Tatjana; Larsson, Chatarina et al.

Part of BMC Genomics, 2013

• DOI for Gene rearrangements in hormone receptor negative breast cancers revealed by mate pair sequencing
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N-Acyl Taurines are Anti-Proliferative in Prostate Cancer Cells

Chatzakos, Vicky; Slatis, Katharina; Djureinovic, Tatjana; Helleday, Thomas et al.

Part of Lipids, p. 355-361, 2012

• DOI for N-Acyl Taurines are Anti-Proliferative in Prostate Cancer Cells

Clonal evolution patterns in high-risk chronic lymphocytic leukemia treated with ibrutinib

Mattsson, Mattias; Ljungström, Viktor; Djureinovic, Tatjana; Mansouri, Larry et al.