Nils Landegren

Autoantibody repertoire analysis in paraneoplastic pemphigus reveals novel targets linked to mucocutaneous blistering and bronchiolitis obliterans

Eriksson, Daniel; Aranda-Guillén, Maribel; Ishii, Norito; Cederholm, Axel et al.

Part of Communications Medicine, 2026

• DOI for Autoantibody repertoire analysis in paraneoplastic pemphigus reveals novel targets linked to mucocutaneous blistering and bronchiolitis obliterans
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Immune system adaptation during gender-affirming testosterone treatment

Lakshmikanth, Tadepally; Consiglio, Camila; Sardh, Fabian; Forlin, Rikard et al.

Part of Nature, p. 155-164, 2024

• DOI for Immune system adaptation during gender-affirming testosterone treatment
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Autoantibodies against type I IFNs in humans with alternative NF-_KB pathway deficiency

Le Voyer, Tom; Parent, Audrey V.; Liu, Xian; Cederholm, Axel et al.

Part of Nature, p. 803-813, 2023

• DOI for Autoantibodies against type I IFNs in humans with alternative NF-_KB pathway deficiency
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The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19

Consiglio, Camila Rosat; Cotugno, Nicola; Sardh, Fabian; Pou, Christian et al.

Part of Cell, p. 968-981, 2020

• DOI for The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19
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The autoimmune targets in IPEX are dominated by gut epithelial proteins

Eriksson, Daniel; Bacchetta, Rosa; Gunnarsson, Hörður Ingi; Chan, Alice et al.

Part of Journal of Allergy and Clinical Immunology, p. 327-330, 2019

• DOI for The autoimmune targets in IPEX are dominated by gut epithelial proteins
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Transglutaminase 4 as a prostate autoantigen in male subfertility

Landegren, Nils; Sharon, Donald; Shum, Anthony K.; Khan, Imran S. et al.

Part of Science Translational Medicine, 2015

• DOI for Transglutaminase 4 as a prostate autoantigen in male subfertility

Systemic multi-omics analysis reveals interferon response heterogeneity and links lipid metabolism to immune alterations in severe COVID-19

Lira-Junior, Ronaldo; Ambikan, Anoop T.; Cederholm, Axel; Rezene, Sefanit et al.

Part of Genome Medicine, 2026

• DOI for Systemic multi-omics analysis reveals interferon response heterogeneity and links lipid metabolism to immune alterations in severe COVID-19
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Editorial: Gender affirming hormone therapy and its immunological implications

Leffler, Jonatan; Holmberg, Mats; Landegren, Nils

Part of Frontiers in Immunology, 2026

• DOI for Editorial: Gender affirming hormone therapy and its immunological implications
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Somatic deficiency of the human E3 ubiquitin ligase CBL in leukocytes impairs B cell but not T cell development and function

Vatovec, Taja; Neehus, Anna-Lena; Jackson, Katherine J. L.; Avery, Danielle T. et al.

Part of Nature Immunology, p. 308-322, 2026

• DOI for Somatic deficiency of the human E3 ubiquitin ligase CBL in leukocytes impairs B cell but not T cell development and function
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Autoantibody repertoire analysis in paraneoplastic pemphigus reveals novel targets linked to mucocutaneous blistering and bronchiolitis obliterans

Eriksson, Daniel; Aranda-Guillén, Maribel; Ishii, Norito; Cederholm, Axel et al.

Part of Communications Medicine, 2026

• DOI for Autoantibody repertoire analysis in paraneoplastic pemphigus reveals novel targets linked to mucocutaneous blistering and bronchiolitis obliterans
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Idiopathic inflammatory myopathies lack neutralising autoantibodies to type- I, II and III interferons

Behere, Anish; Mildner, Hedvig; Peralta Garcia, Irene; Pérez Bucio, César et al.

Part of RMD Open, 2025

• DOI for Idiopathic inflammatory myopathies lack neutralising autoantibodies to type- I, II and III interferons
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Systemic multi-omics analysis reveals interferon response heterogeneity and links lipid metabolism to immune alterations in severe COVID-19

Lira-Junior, Ronaldo; Ambikan, Anoop T.; Cederholm, Axel; Rezene, Sefanit et al.

Part of Genome Medicine, 2026

• DOI for Systemic multi-omics analysis reveals interferon response heterogeneity and links lipid metabolism to immune alterations in severe COVID-19
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Editorial: Gender affirming hormone therapy and its immunological implications

Leffler, Jonatan; Holmberg, Mats; Landegren, Nils

Part of Frontiers in Immunology, 2026

• DOI for Editorial: Gender affirming hormone therapy and its immunological implications
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Somatic deficiency of the human E3 ubiquitin ligase CBL in leukocytes impairs B cell but not T cell development and function

Vatovec, Taja; Neehus, Anna-Lena; Jackson, Katherine J. L.; Avery, Danielle T. et al.

Part of Nature Immunology, p. 308-322, 2026

• DOI for Somatic deficiency of the human E3 ubiquitin ligase CBL in leukocytes impairs B cell but not T cell development and function
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Autoantibody repertoire analysis in paraneoplastic pemphigus reveals novel targets linked to mucocutaneous blistering and bronchiolitis obliterans

Eriksson, Daniel; Aranda-Guillén, Maribel; Ishii, Norito; Cederholm, Axel et al.

Part of Communications Medicine, 2026

• DOI for Autoantibody repertoire analysis in paraneoplastic pemphigus reveals novel targets linked to mucocutaneous blistering and bronchiolitis obliterans
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Idiopathic inflammatory myopathies lack neutralising autoantibodies to type- I, II and III interferons

Behere, Anish; Mildner, Hedvig; Peralta Garcia, Irene; Pérez Bucio, César et al.

Part of RMD Open, 2025

• DOI for Idiopathic inflammatory myopathies lack neutralising autoantibodies to type- I, II and III interferons
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Immune-coagulation dynamics in severe COVID-19 revealed by autoantibody profiling and multi-omics integration

Ambikan, Anoop T.; Cederholm, Axel; Rezene, Sefanit; Aranda-Guillen, Maribel et al.

Part of Scientific Reports, 2025

• DOI for Immune-coagulation dynamics in severe COVID-19 revealed by autoantibody profiling and multi-omics integration
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Autoantibodies neutralizing type I IFNs in patients with fulminant herpes simplex virus hepatitis

Gervais, Adrian; Marchal, Astrid; Boucherit, Soraya; Abi Haidar, Anthony et al.

Part of Journal of Experimental Medicine, 2025

• DOI for Autoantibodies neutralizing type I IFNs in patients with fulminant herpes simplex virus hepatitis
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Evaluating IL1RA-Autoantibodies Across SARS-CoV-2-Related Diseases

Behere, Anish; Hallberg, Pär; Cederholm, Axel; Cavalli, Marco et al.

Part of Scandinavian Journal of Immunology, 2025

• DOI for Evaluating IL1RA-Autoantibodies Across SARS-CoV-2-Related Diseases
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Human LY9 governs CD4⁺ T cell IFN-γ immunity to Mycobacterium tuberculosis

Ogishi, Masato; Puchan, Julia; Yang, Rui; Arias, Andres Augusto et al.

Part of Science immunology, 2025

• DOI for Human LY9 governs CD4⁺ T cell IFN-γ immunity to Mycobacterium tuberculosis

Genome-wide association study of myocarditis and pericarditis following COVID-19 vaccination

Cavalli, Marco; Eriksson, Niclas; Baron, Tomasz; Yalcinkaya, Ahmet et al.

Part of npj Vaccines, 2025

• DOI for Genome-wide association study of myocarditis and pericarditis following COVID-19 vaccination
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No link between type I interferon autoantibody positivity and adverse reactions to COVID-19 vaccines

Yalcinkaya, Ahmet; Cavalli, Marco; Cederholm, Axel; Aranda-Guillen, Maribel et al.

Part of npj Vaccines, 2024

• DOI for No link between type I interferon autoantibody positivity and adverse reactions to COVID-19 vaccines
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Autoinflammation in patients with leukocytic CBL loss of heterozygosity is caused by constitutive ERK-mediated monocyte activation

Bohlen, Jonathan; Bagarić, Ivan; Vatovec, Taja; Ogishi, Masato et al.

Part of Journal of Clinical Investigation, 2024

• DOI for Autoinflammation in patients with leukocytic CBL loss of heterozygosity is caused by constitutive ERK-mediated monocyte activation
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Immune system adaptation during gender-affirming testosterone treatment

Lakshmikanth, Tadepally; Consiglio, Camila; Sardh, Fabian; Forlin, Rikard et al.

Part of Nature, p. 155-164, 2024

• DOI for Immune system adaptation during gender-affirming testosterone treatment
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Autoantibodies to protein S may explain rare cases of coagulopathy following COVID-19 vaccination

Yalcinkaya, Ahmet; Cavalli, Marco; Aranda-Guillén, Maribel; Cederholm, Axel et al.

Part of Scientific Reports, 2024

• DOI for Autoantibodies to protein S may explain rare cases of coagulopathy following COVID-19 vaccination
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IL-7–dependent and –independent lineages of IL-7R–dependent human T cells

Arango-Franco, Carlos A.; Ogishi, Masato; Unger, Susanne; Delmonte, Ottavia M. et al.

Part of Journal of Clinical Investigation, 2024

• DOI for IL-7–dependent and –independent lineages of IL-7R–dependent human T cells
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Inherited human RelB deficiency impairs innate and adaptive immunity to infection

Le Voyer, Tom; Renkilaraj, Majistor Raj Luxman Maglorius; Moriya, Kunihiko; Pérez Lorenzo, Malena et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2024

• DOI for Inherited human RelB deficiency impairs innate and adaptive immunity to infection
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Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB1*15:02 or 16:02 individuals

Peel, Jessica N.; Yang, Rui; Le Voyer, Tom; Gervais, Adrian et al.

Part of Journal of Clinical Investigation, 2024

• DOI for Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB1*15:02 or 16:02 individuals
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The immunopathological landscape of human pre-TCRα deficiency: From rare to common variants

Materna, Marie; Delmonte, Ottavia M.; Bosticardo, Marita; Momenilandi, Mana et al.

Part of Science, 2024

• DOI for The immunopathological landscape of human pre-TCRα deficiency: From rare to common variants

FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice

Momenilandi, Mana; Lévy, Romain; Sobrino, Steicy; Li, Jingwei et al.

Part of Cell, p. 2817-2.837e+34, 2024

• DOI for FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice
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Autoantibodies against type I IFNs in humans with alternative NF-_KB pathway deficiency

Le Voyer, Tom; Parent, Audrey V.; Liu, Xian; Cederholm, Axel et al.

Part of Nature, p. 803-813, 2023

• DOI for Autoantibodies against type I IFNs in humans with alternative NF-_KB pathway deficiency
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Relation between HLA and copy number variation of steroid 21-hydroxylase in a Swedish cohort of patients with autoimmune Addison's disease

Lundtoft, Christian; Eriksson, Daniel; Bianchi, Matteo; Aranda-Guillen, Maribel et al.

Part of European Journal of Endocrinology, p. 235-241, 2023

• DOI for Relation between HLA and copy number variation of steroid 21-hydroxylase in a Swedish cohort of patients with autoimmune Addison's disease
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X-Linked TLR7 Deficiency Underlies Critical COVID-19 Pneumonia in a Male Patient with Ataxia-Telangiectasia

Abolhassani, Hassan; Vosughimotlagh, Ahmad; Asano, Takaki; Landegren, Nils et al.

Part of Journal of Clinical Immunology, p. 1-9, 2022

• DOI for X-Linked TLR7 Deficiency Underlies Critical COVID-19 Pneumonia in a Male Patient with Ataxia-Telangiectasia
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Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ

Al-Amin, Rasel A.; Johansson, Lars; Abdurakhmanov, Eldar; Landegren, Nils et al.

Part of Nucleic Acids Research, 2022

• DOI for Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ
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Genetic and immunologic evaluation of children with inborn errors of immunity and severe or critical COVID-19

Abolhassani, Hassan; Delavari, Samaneh; Landegren, Nils; Shokri, Sima et al.

Part of Journal of Allergy and Clinical Immunology, p. 1059-1073, 2022

• DOI for Genetic and immunologic evaluation of children with inborn errors of immunity and severe or critical COVID-19
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Autoantibody discovery across monogenic, acquired, and COVID-19-associated autoimmunity with scalable PhIP-seq

Vazquez, Sara E.; Mann, Sabrina A.; Bodansky, Aaron; Kung, Andrew F. et al.

Part of eLIFE, 2022

• DOI for Autoantibody discovery across monogenic, acquired, and COVID-19-associated autoimmunity with scalable PhIP-seq
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Inherited IFNAR1 Deficiency in a Child with Both Critical COVID-19 Pneumonia and Multisystem Inflammatory Syndrome

Abolhassani, Hassan; Landegren, Nils; Bastard, Paul; Materna, Marie et al.

Part of Journal of Clinical Immunology, p. 471-483, 2022

• DOI for Inherited IFNAR1 Deficiency in a Child with Both Critical COVID-19 Pneumonia and Multisystem Inflammatory Syndrome
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GWAS for autoimmune Addison's disease identifies multiple risk loci and highlights AIRE in disease susceptibility

Eriksson, Daniel; Röyrvik, Ellen Christine; Aranda-Guillen, Maribel; Berger, Amund Holte et al.

Part of Nature Communications, 2021

• DOI for GWAS for autoimmune Addison's disease identifies multiple risk loci and highlights AIRE in disease susceptibility
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Severe COVID-19 in an APS1 patient with interferon autoantibodies treated with plasmapheresis

Lemarquis, Andri; Campbell, Tessa; Aranda-Guillén, Maribel; Hennings, Viktoria et al.

Part of Journal of Allergy and Clinical Immunology, p. 96-98, 2021

• DOI for Severe COVID-19 in an APS1 patient with interferon autoantibodies treated with plasmapheresis

The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19

Consiglio, Camila Rosat; Cotugno, Nicola; Sardh, Fabian; Pou, Christian et al.

Part of Cell, p. 968-981, 2020

• DOI for The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19
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The autoimmune targets in IPEX are dominated by gut epithelial proteins

Eriksson, Daniel; Bacchetta, Rosa; Gunnarsson, Hörður Ingi; Chan, Alice et al.

Part of Journal of Allergy and Clinical Immunology, p. 327-330, 2019

• DOI for The autoimmune targets in IPEX are dominated by gut epithelial proteins
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Comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'

Landegren, Nils; Rosen, Lindsey B.; Freyhult, Eva; Eriksson, Daniel et al.

Part of eLIFE, 2019

• DOI for Comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'
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Cytokine Autoantibody Screening in the Swedish Addison Registry Identifies Patients With Undiagnosed APS1

Eriksson, Daniel; Dalin, Frida; Eriksson, Gabriel Nordling; Landegren, Nils et al.

Part of Journal of Clinical Endocrinology and Metabolism, p. 179-186, 2018

• DOI for Cytokine Autoantibody Screening in the Swedish Addison Registry Identifies Patients With Undiagnosed APS1
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Common genetic variation in the autoimmune regulator (AIRE) locus is associated with autoimmune Addison's disease in Sweden

Eriksson, Daniel; Bianchi, Matteo; Landegren, Nils; Dalin, Frida et al.

Part of Scientific Reports, 2018

• DOI for Common genetic variation in the autoimmune regulator (AIRE) locus is associated with autoimmune Addison's disease in Sweden
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ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease

Bremer, Hanna D.; Landegren, Nils; Sjöberg, Ronald; Hallgren, Åsa et al.

Part of Scientific Reports, 2018

• DOI for ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease
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A Longitudinal Follow-up of Autoimmune Polyendocrine Syndrome Type 1

Bruserud, Oyvind; Oftedal, Bergithe E.; Landegren, Nils; Erichsen, Martina M. et al.

Part of Journal of Clinical Endocrinology and Metabolism, p. 2975-2983, 2016

• DOI for A Longitudinal Follow-up of Autoimmune Polyendocrine Syndrome Type 1
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Aryl Hydrocarbon Receptor-Interacting Protein-Like 1 in Cancer-Associated Retinopathy

Dalin, Frida; Adamus, Grazyna; Yang, Sufang; Landgren, Eva et al.

Part of Ophthalmology, p. 1401-1404, 2016

• DOI for Aryl Hydrocarbon Receptor-Interacting Protein-Like 1 in Cancer-Associated Retinopathy

Autoantibodies Targeting a Collecting Duct-Specific Water Channel in Tubulointerstitial Nephritis.

Landegren, Nils; Pourmousa Lindberg, Mina; Skov, Jakob; Hallgren, Åsa et al.

Part of Journal of the American Society of Nephrology, p. 3220-3228, 2016

• DOI for Autoantibodies Targeting a Collecting Duct-Specific Water Channel in Tubulointerstitial Nephritis.

Aryl Hydrocarbon Receptor-Interacting Protein-Like 1 in Cancer-Associated Retinopathy

Dalin, Frida; Adamus, Grazyna; Yang, Sufang; Landgren, Eva et al.

Part of Ophthalmology, p. 1401-1404, 2016

• DOI for Aryl Hydrocarbon Receptor-Interacting Protein-Like 1 in Cancer-Associated Retinopathy

Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1

Landegren, Nils; Sharon, Donald; Freyhult, Eva; Hallgren, Åsa et al.

Part of Scientific Reports, 2016

• DOI for Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1
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Extended exome sequencing identifies BACH2 as a novel major risk locus for Addison's disease

Eriksson, D.; Bianchi, Matteo; Landegren, Nils; Nordin, Jessika et al.

Part of Journal of Internal Medicine, p. 595-608, 2016

• DOI for Extended exome sequencing identifies BACH2 as a novel major risk locus for Addison's disease
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Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies

Albrecht, Inka; Wick, Cecilia; Hallgren, Åsa; Tjärnlund, Anna et al.

Part of Journal of Clinical Investigation, p. 4612-4624, 2015

• DOI for Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies

Transglutaminase 4 as a prostate autoantigen in male subfertility

Landegren, Nils; Sharon, Donald; Shum, Anthony K.; Khan, Imran S. et al.

Part of Science Translational Medicine, 2015

• DOI for Transglutaminase 4 as a prostate autoantigen in male subfertility

Lack of evidence for a role of islet autoimmunity in the aetiology of canine diabetes mellitus

Ahlgren, Kerstin M; Fall, Tove; Landegren, Nils; Grimelius, Lars et al.

Part of PLOS ONE, 2014

• DOI for Lack of evidence for a role of islet autoimmunity in the aetiology of canine diabetes mellitus
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Mechanisms of autoimmune-mediated paraneoplastic syndromes: immune tolerance and disease pathogenesis

Perez-Bucio, Cesar; Behere, Anish; Landegren, Nils

Part of Frontiers in Immunology, 2025

• DOI for Mechanisms of autoimmune-mediated paraneoplastic syndromes: immune tolerance and disease pathogenesis
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Immune dynamics throughout life in relation to sex hormones and perspectives gained from gender-affirming hormone therapy

Yalcinkaya, Ahmet; Yalcinkaya, Rumeysa; Sardh, Fabian; Landegren, Nils

Part of Frontiers in Immunology, 2025

• DOI for Immune dynamics throughout life in relation to sex hormones and perspectives gained from gender-affirming hormone therapy
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Sex dimorphism in the tumor microenvironment: From bench to bedside and back

He, Fei; Furones, Andrea Rodgers; Landegren, Nils; Fuxe, Jonas et al.

Part of Seminars in Cancer Biology, p. 166-179, 2022

• DOI for Sex dimorphism in the tumor microenvironment: From bench to bedside and back
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Autoantibodies and SARS-CoV2 infection: The spectrum from association to clinical implication. Report of the 15th Dresden Symposium on Autoantibodies

Damoiseaux, Jan; Dotan, Arad; Fritzler, Marvin J.; Bogdanos, Dimitrios P. et al.

Part of Autoimmunity Reviews, 2022

• DOI for Autoantibodies and SARS-CoV2 infection: The spectrum from association to clinical implication. Report of the 15th Dresden Symposium on Autoantibodies
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Biomarker Discovery in Tissue-specific Autoimmune Disease

Landegren, Nils

2015

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Target Engagement-Mediated Amplification for Monitoring Drug-Target Interactions in Situ

Al-Amin, Rasel A.; Johansson, Lars; Landegren, Nils; Löf, Liza et al.

Autoantibodies Targeting a Collecting Duct-specific Water Channel in Tubulointerstitial Nephritis

Landegren, Nils