Xiaomei Chen

Integrated Modeling of Digital-Motor and Clinician-Reported Outcomes Using Item Response Theory: Towards Powerful Trials for Rare Neurological Diseases

Hamdan, Alzahra; Traschütz, Andreas; Beichert, Lukas; Chen, Xiaomei et al.

Part of CPT, p. 1857-1868, 2025

• DOI for Integrated Modeling of Digital-Motor and Clinician-Reported Outcomes Using Item Response Theory: Towards Powerful Trials for Rare Neurological Diseases
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A Pharmacometrics-Informed Trial Simulation Framework for Optimizing Study Designs for Disease-Modifying Treatments in Rare Neurological Disorders

Ryeznik, Yevgen; Hilgers, Ralf-Dieter; Heussen, Nicole; Comets, Emmanuelle et al.

Part of CPT, p. 1705-1714, 2025

• DOI for A Pharmacometrics-Informed Trial Simulation Framework for Optimizing Study Designs for Disease-Modifying Treatments in Rare Neurological Disorders
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Evaluation of model-integrated evidence approaches for pharmacokinetic bioequivalence studies using model averaging methods

Bjugård Nyberg, Henrik; Chen, Xiaomei; Donnelly, Mark; Fang, Lanyan et al.

Part of CPT, p. 1748-1761, 2024

• DOI for Evaluation of model-integrated evidence approaches for pharmacokinetic bioequivalence studies using model averaging methods
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A fully automatic tool for development of population pharmacokinetic models

Chen, Xiaomei; Nordgren, Rikard; Belin, Stella; Hamdan, Alzahra et al.

Part of CPT, p. 1784-1797, 2024

• DOI for A fully automatic tool for development of population pharmacokinetic models
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Longitudinal Analysis of Natural History Progression of Rare and Ultra‐Rare Cerebellar Ataxias Using Item Response Theory

Hamdan, Alzahra; Hendrickx, Niels; Hooker, Andrew C.; Chen, Xiaomei et al.

Part of Clinical Pharmacology and Therapeutics, p. 1593-1605, 2024

• DOI for Longitudinal Analysis of Natural History Progression of Rare and Ultra‐Rare Cerebellar Ataxias Using Item Response Theory
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Integrated Modeling of Digital-Motor and Clinician-Reported Outcomes Using Item Response Theory: Towards Powerful Trials for Rare Neurological Diseases

Hamdan, Alzahra; Traschütz, Andreas; Beichert, Lukas; Chen, Xiaomei et al.

Part of CPT, p. 1857-1868, 2025

• DOI for Integrated Modeling of Digital-Motor and Clinician-Reported Outcomes Using Item Response Theory: Towards Powerful Trials for Rare Neurological Diseases
• Download full text (pdf) of Integrated Modeling of Digital-Motor and Clinician-Reported Outcomes Using Item Response Theory: Towards Powerful Trials for Rare Neurological Diseases

A Pharmacometrics-Informed Trial Simulation Framework for Optimizing Study Designs for Disease-Modifying Treatments in Rare Neurological Disorders

Ryeznik, Yevgen; Hilgers, Ralf-Dieter; Heussen, Nicole; Comets, Emmanuelle et al.

Part of CPT, p. 1705-1714, 2025

• DOI for A Pharmacometrics-Informed Trial Simulation Framework for Optimizing Study Designs for Disease-Modifying Treatments in Rare Neurological Disorders
• Download full text (pdf) of A Pharmacometrics-Informed Trial Simulation Framework for Optimizing Study Designs for Disease-Modifying Treatments in Rare Neurological Disorders

Evaluation of model-integrated evidence approaches for pharmacokinetic bioequivalence studies using model averaging methods

Bjugård Nyberg, Henrik; Chen, Xiaomei; Donnelly, Mark; Fang, Lanyan et al.

Part of CPT, p. 1748-1761, 2024

• DOI for Evaluation of model-integrated evidence approaches for pharmacokinetic bioequivalence studies using model averaging methods
• Download full text (pdf) of Evaluation of model-integrated evidence approaches for pharmacokinetic bioequivalence studies using model averaging methods

A fully automatic tool for development of population pharmacokinetic models

Chen, Xiaomei; Nordgren, Rikard; Belin, Stella; Hamdan, Alzahra et al.

Part of CPT, p. 1784-1797, 2024

• DOI for A fully automatic tool for development of population pharmacokinetic models
• Download full text (pdf) of A fully automatic tool for development of population pharmacokinetic models

Longitudinal Analysis of Natural History Progression of Rare and Ultra‐Rare Cerebellar Ataxias Using Item Response Theory

Hamdan, Alzahra; Hendrickx, Niels; Hooker, Andrew C.; Chen, Xiaomei et al.

Part of Clinical Pharmacology and Therapeutics, p. 1593-1605, 2024

• DOI for Longitudinal Analysis of Natural History Progression of Rare and Ultra‐Rare Cerebellar Ataxias Using Item Response Theory
• Download full text (pdf) of Longitudinal Analysis of Natural History Progression of Rare and Ultra‐Rare Cerebellar Ataxias Using Item Response Theory

Development and comparison of model-integrated evidence approaches for bioequivalence studies with pharmacokinetic end points

Chen, Xiaomei; Bjugård Nyberg, Henrik; Donnelly, Mark; Zhao, Liang et al.

Part of CPT, p. 1734-1747, 2024

• DOI for Development and comparison of model-integrated evidence approaches for bioequivalence studies with pharmacokinetic end points
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Item performance of the scale for the assessment and rating of ataxia in rare and ultra-rare genetic ataxias

Hamdan, Alzahra; Hooker, Andrew C.; Chen, Xiaomei; Traschütz, Andreas et al.

Part of CPT, p. 1327-1340, 2024

• DOI for Item performance of the scale for the assessment and rating of ataxia in rare and ultra-rare genetic ataxias
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Model-Informed Drug Development for Long-Acting Injectable Products: Summary of American College of Clinical Pharmacology Symposium

Sharan, Satish; Fang, Lanyan; Lukacova, Viera; Chen, Xiaomei et al.

Part of Clinical Pharmacology in Drug Development, p. 220-228, 2021

• DOI for Model-Informed Drug Development for Long-Acting Injectable Products: Summary of American College of Clinical Pharmacology Symposium

Revisiting atenolol as a low passive permeability marker

Chen, Xiaomei; Slättengren, Tim; de Lange, Elizabeth C. M.; Smith, David E. et al.

Part of Fluids and Barriers of the CNS, 2017

• DOI for Revisiting atenolol as a low passive permeability marker
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Effect of transporter inhibitioin on the distribution of cefadroxil in rat brain

Chen, Xiaomei; Loryan, Irena; Payan, Maryam; Keep, Richard F. et al.

Part of Fluids and Barriers of the CNS, 2014

• DOI for Effect of transporter inhibitioin on the distribution of cefadroxil in rat brain
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Effect of transporter inhibition on the distribution of cefadroxil in rat brain

Chen, Xiaomei; Loryan, Irena; Payan, Maryam; Keep, Richard et al.

Part of Fluids and Barriers of the CNS, 2014

• DOI for Effect of transporter inhibition on the distribution of cefadroxil in rat brain
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