Stefan Gustafsson

Multi-cohort proteogenomic analyses reveal genetic effects across the proteome and diseasome

Koprulu, Mine; Smith-Byrne, Karl; Ferolito, Brian Richard; Macdonald-Dunlop, Erin et al.

Part of Cell, p. 3339-+, 2026

• DOI for Multi-cohort proteogenomic analyses reveal genetic effects across the proteome and diseasome

A deep learning ECG model for identification and localization of occlusion myocardial infarction

Gustafsson, Stefan; Ribeiro, Antônio H.; Gedon, Daniel; Abreu, Petrus E. O. G. B. et al.

Part of Nature Communications, 2026

• DOI for A deep learning ECG model for identification and localization of occlusion myocardial infarction
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Cardiomyopathies: Nationwide Trends in Prevalence, Incidence, and Mortality (2004-2023)

Lindholm, Daniel; Ribom, Gustav; Gustafsson, Stefan; Pol, Tymon et al.

Part of Journal of the American College of Cardiology, p. 1087-1090, 2026

• DOI for Cardiomyopathies: Nationwide Trends in Prevalence, Incidence, and Mortality (2004-2023)

Persistence to antihypertensive drug classes in uncomplicated hypertension: a nationwide Swedish cohort study

Laurell, Karl; Gustafsson, Stefan; Lampa, Erik; Zachariah, Dave et al.

Part of eClinicalMedicine, 2026

• DOI for Persistence to antihypertensive drug classes in uncomplicated hypertension: a nationwide Swedish cohort study
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Polygenic prediction of body mass index and obesity through the life course and across ancestries

Smit, Roelof A. J.; Gustafsson, Stefan; Lind, Lars; Loos, Ruth J. F.

Part of Nature Medicine, p. 3151-3168, 2025

• DOI for Polygenic prediction of body mass index and obesity through the life course and across ancestries
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Multi-cohort proteogenomic analyses reveal genetic effects across the proteome and diseasome

Koprulu, Mine; Smith-Byrne, Karl; Ferolito, Brian Richard; Macdonald-Dunlop, Erin et al.

Part of Cell, p. 3339-+, 2026

• DOI for Multi-cohort proteogenomic analyses reveal genetic effects across the proteome and diseasome

A deep learning ECG model for identification and localization of occlusion myocardial infarction

Gustafsson, Stefan; Ribeiro, Antônio H.; Gedon, Daniel; Abreu, Petrus E. O. G. B. et al.

Part of Nature Communications, 2026

• DOI for A deep learning ECG model for identification and localization of occlusion myocardial infarction
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Cardiomyopathies: Nationwide Trends in Prevalence, Incidence, and Mortality (2004-2023)

Lindholm, Daniel; Ribom, Gustav; Gustafsson, Stefan; Pol, Tymon et al.

Part of Journal of the American College of Cardiology, p. 1087-1090, 2026

• DOI for Cardiomyopathies: Nationwide Trends in Prevalence, Incidence, and Mortality (2004-2023)

Persistence to antihypertensive drug classes in uncomplicated hypertension: a nationwide Swedish cohort study

Laurell, Karl; Gustafsson, Stefan; Lampa, Erik; Zachariah, Dave et al.

Part of eClinicalMedicine, 2026

• DOI for Persistence to antihypertensive drug classes in uncomplicated hypertension: a nationwide Swedish cohort study
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Polygenic prediction of body mass index and obesity through the life course and across ancestries

Smit, Roelof A. J.; Gustafsson, Stefan; Lind, Lars; Loos, Ruth J. F.

Part of Nature Medicine, p. 3151-3168, 2025

• DOI for Polygenic prediction of body mass index and obesity through the life course and across ancestries
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Cross-sectional, interventional, and causal investigation of insulin sensitivity using plasma proteomics in diverse populations

Kho, Pik Fang; Wary, Neil; Zanetti, Daniela; Abbasi, Fahim et al.

Part of Metabolism, 2025

• DOI for Cross-sectional, interventional, and causal investigation of insulin sensitivity using plasma proteomics in diverse populations

Markers of imminent myocardial infarction

Gustafsson, Stefan; Lampa, Erik; Jensevik Eriksson, Karin; Butterworth, Adam S. et al.

Part of Nature Cardiovascular Research, p. 130-139, 2024

• DOI for Markers of imminent myocardial infarction
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Person-Centered Web-Based Mobile Health System (Symptoms) for Reporting Symptoms in COVID-19 Vaccinated Individuals: Observational Study of System, Users, and Symptoms

Gustafson Hedov, Emelie; Nyberg, Fredrik; Gustafsson, Stefan; Li, Huiqi et al.

Part of JMIR Formative Research, 2024

• DOI for Person-Centered Web-Based Mobile Health System (Symptoms) for Reporting Symptoms in COVID-19 Vaccinated Individuals: Observational Study of System, Users, and Symptoms
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Heart failure treatment in the last years of life: A nationwide study of 364 000 individuals

Sundström, Johan; Gustafsson, Stefan; Cars, Thomas; Lindholm, Daniel P

Part of European Journal of Heart Failure, p. 2443-2450, 2024

• DOI for Heart failure treatment in the last years of life: A nationwide study of 364 000 individuals
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Evaluating regression and probabilistic methods for ECG-based electrolyte prediction

von Bachmann, Philipp; Gedon, Daniel; Gustafsson, Fredrik K.; Ribeiro, Antônio H. et al.

Part of Scientific Reports, 2024

• DOI for Evaluating regression and probabilistic methods for ECG-based electrolyte prediction
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Loci for insulin processing and secretion provide insight into type 2 diabetes risk

Broadaway, K Alaine; Yin, Xianyong; Williamson, Alice; Parsons, Victoria A et al.

Part of American Journal of Human Genetics, p. 284-299, 2023

• DOI for Loci for insulin processing and secretion provide insight into type 2 diabetes risk

Plasma Protein Profiling of Incident Cardiovascular Diseases: A Multisample Evaluation

Lind, Lars; Titova, Olga; Zeng, Rui; Zanetti, Daniela et al.

Part of CIRCULATION-GENOMIC AND PRECISION MEDICINE, 2023

• DOI for Plasma Protein Profiling of Incident Cardiovascular Diseases: A Multisample Evaluation
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Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases

Carland, Corinne; Png, Grace; Malarstig, Anders; Kho, Pik Fang et al.

Part of Clinical Proteomics, 2023

• DOI for Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases
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Fibroblast Growth Factor-23 and Risk of Cardiovascular Diseases A Mendelian Randomization Study

Donovan, Killian; Herrington, William G.; Pare, Guillaume; Pigeyre, Marie et al.

Part of American Society of Nephrology. Clinical Journal, p. 17-27, 2023

• DOI for Fibroblast Growth Factor-23 and Risk of Cardiovascular Diseases A Mendelian Randomization Study
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Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

Williamson, Alice; Norris, Dougall M; Yin, Xianyong; Broadaway, K Alaine et al.

Part of Nature Genetics, p. 973-983, 2023

• DOI for Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

Plasma proteomic signatures of a direct measure of insulin sensitivity in two population cohorts

Zanetti, Daniela; Stell, Laurel; Gustafsson, Stefan; Abbasi, Fahim et al.

Part of Diabetologia, p. 1643-1654, 2023

• DOI for Plasma proteomic signatures of a direct measure of insulin sensitivity in two population cohorts
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Single-cell transcriptome dataset of human and mouse in vitro adipogenesis models

Li, Jiehan; Jin, Christopher; Gustafsson, Stefan; Rao, Abhiram et al.

Part of Scientific Data, 2023

• DOI for Single-cell transcriptome dataset of human and mouse in vitro adipogenesis models
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A saturated map of common genetic variants associated with human height

Yengo, Loic; Gustafsson, Stefan; Lind, Lars; Hirschhorn, Joel N.

Part of Nature, p. 704-712, 2022

• DOI for A saturated map of common genetic variants associated with human height
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Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Kanoni, Stavroula; Gustafsson, Stefan; Lind, Lars; Ingelsson, Erik et al.

Part of Genome Biology, 2022

• DOI for Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
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Stroke genetics informs drug discovery and risk prediction across ancestries

Mishra, Aniket; den Hoed, Marcel; Gustafsson, Stefan; Ingelsson, Erik et al.

Part of Nature, p. 115-+, 2022

• DOI for Stroke genetics informs drug discovery and risk prediction across ancestries
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Genetic Landscape of the ACE2 Coronavirus Receptor

Yang, Zhijian; Macdonald-Dunlop, Erin; Chen, Jiantao; Zhai, Ranran et al.

Part of Circulation, p. 1398-1411, 2022

• DOI for Genetic Landscape of the ACE2 Coronavirus Receptor
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Development and validation of deep learning ECG-based prediction of myocardial infarction in emergency department patients

Gustafsson, Stefan; Gedon, Daniel; Lampa, Erik; Horta Ribeiro, Antônio et al.

Part of Scientific Reports, 2022

• DOI for Development and validation of deep learning ECG-based prediction of myocardial infarction in emergency department patients
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A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

Ramdas, Shweta; Gustafsson, Stefan; Lind, Lars; Ingelsson, Erik et al.

Part of American Journal of Human Genetics, p. 1366-1387, 2022

• DOI for A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

A genome-wide association study in a large community-based cohort identifies multiple loci associated with susceptibility to bacterial and viral infections

Tängdén, Thomas; Gustafsson, Stefan; Rao, Abhiram S.; Ingelsson, Erik

Part of Scientific Reports, 2022

• DOI for A genome-wide association study in a large community-based cohort identifies multiple loci associated with susceptibility to bacterial and viral infections
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Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19

Klaric, Lucija; Gisby, Jack S; Papadaki, Artemis; Muckian, Marisa D et al.

Part of medRxiv : the preprint server for health sciences, p. 1-28, 2021

• DOI for Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19

The power of genetic diversity in genome-wide association studies of lipids

Graham, Sarah E.; Gustafsson, Stefan; Lind, Lars; Ingelsson, Erik et al.

Part of Nature, p. 675-679, 2021

• DOI for The power of genetic diversity in genome-wide association studies of lipids

Large-Scale Plasma Protein Profiling of Incident Myocardial Infarction, Ischemic Stroke, and Heart Failure

Lind, Lars; Zanetti, Daniela; Ingelsson, Martin; Gustafsson, Stefan et al.

Part of Journal of the American Heart Association, 2021

• DOI for Large-Scale Plasma Protein Profiling of Incident Myocardial Infarction, Ischemic Stroke, and Heart Failure
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A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids

Jhun, Mina-A; Mendelson, Michael; Wilson, Rory; Gondalia, Rahul et al.

Part of Nature Communications, 2021

• DOI for A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids
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Renin-Angiotensin Aldosterone System Inhibitors in Primary Prevention and COVID-19

Loader, Jordan; Lampa, Erik; Gustafsson, Stefan; Cars, Thomas et al.

Part of Journal of the American Heart Association, 2021

• DOI for Renin-Angiotensin Aldosterone System Inhibitors in Primary Prevention and COVID-19
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The trans-ancestral genomic architecture of glycemic traits

Chen, Ji; Gustafsson, Stefan; Sennblad, Bengt; Lind, Lars et al.

Part of Nature Genetics, p. 840-860, 2021

• DOI for The trans-ancestral genomic architecture of glycemic traits

Comprehensive Investigation of Circulating Biomarkers and Their Causal Role in Atherosclerosis-Related Risk Factors and Clinical Events

Zanetti, Daniela; Gustafsson, Stefan; Assimes, Themistocles L.; Ingelsson, Erik

Part of Circulation, p. 671-685, 2020

• DOI for Comprehensive Investigation of Circulating Biomarkers and Their Causal Role in Atherosclerosis-Related Risk Factors and Clinical Events

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

Folkersen, Lasse; Gustafsson, Stefan; Wang, Qin; Hvidberg Hansen, Daniel et al.

Part of Nature Metabolism, p. 1135-1148, 2020

• DOI for Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

Identification of 22 novel loci associated with urinary biomarkers of albumin, sodium, and potassium excretion

Zanetti, Daniela; Rao, Abhiram; Gustafsson, Stefan; Assimes, Themistocles L. et al.

Part of Kidney International, p. 1197-1208, 2019

• DOI for Identification of 22 novel loci associated with urinary biomarkers of albumin, sodium, and potassium excretion

Proteomic Analysis of Longitudinal Changes in Blood Pressure

Yi-Ting, Lin; Fall, Tove; Hammar, Ulf; Gustafsson, Stefan et al.

Part of Journal of Clinical Medicine, 2019

• DOI for Proteomic Analysis of Longitudinal Changes in Blood Pressure
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Body composition and atrial fibrillation: a Mendelian randomization study

Tikkanen, Emmi; Gustafsson, Stefan; Knowles, Joshua W.; Perez, Marco et al.

Part of European Heart Journal, p. 1277-1282, 2019

• DOI for Body composition and atrial fibrillation: a Mendelian randomization study

Loss of function, missense, and intronic variants in NOTCH1 confer different risks for left ventricular outflow tract obstructive heart defects in two European cohorts

Helle, Emmi; Cordova-Palomera, Aldo; Ojala, Tiina; Saha, Priyanka et al.

Part of Genetic Epidemiology, p. 215-226, 2019

• DOI for Loss of function, missense, and intronic variants in NOTCH1 confer different risks for left ventricular outflow tract obstructive heart defects in two European cohorts

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

Schmidt, Amand F.; Holmes, Michael V.; Preiss, David; Swerdlow, Daniel I. et al.

Part of BMC Cardiovascular Disorders, 2019

• DOI for Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9
• Download full text (pdf) of Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation

Dörr, Marcus; Hamburg, Naomi M.; Müller, Christian; Smith, Nicholas L. et al.

Part of Circulation, 2019

• DOI for Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

Justice, Anne E.; Giedraitis, Vilmantas; Gustafsson, Stefan; Ingelsson, Erik et al.

Part of Nature Genetics, p. 452-469, 2019

• DOI for Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

No evidence of a causal association of type 2 diabetes and glucose metabolism with atrial fibrillation

Harati, Hadi; Zanetti, Daniela; Rao, Abhiram; Gustafsson, Stefan et al.

Part of Diabetologia, p. 800-804, 2019

• DOI for No evidence of a causal association of type 2 diabetes and glucose metabolism with atrial fibrillation

Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes

Pulit, Sara L.; Gustafsson, Stefan; Lind, Lars; Lannfelt, Lars et al.

Part of Neurology Genetics, 2018

• DOI for Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes
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Associations of Circulating Protein Levels With Lipid Fractions in the General Population

Figarska, Sylwia M.; Gustafsson, Stefan; Sundström, Johan; Ärnlöv, Johan et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 2505-2518, 2018

• DOI for Associations of Circulating Protein Levels With Lipid Fractions in the General Population

Associations of Fitness, Physical Activity, Strength, and Genetic Risk With Cardiovascular Disease Longitudinal Analyses in the UK Biobank Study

Tikkanen, Emmi; Gustafsson, Stefan; Ingelsson, Erik

Part of Circulation, p. 2583-2591, 2018

• DOI for Associations of Fitness, Physical Activity, Strength, and Genetic Risk With Cardiovascular Disease Longitudinal Analyses in the UK Biobank Study

Clinical and genetic determinants of varicose veins: a prospective, community-based prospective study of similar to 500,000 individuals

Fukaya, Eri; Flores, Alyssa; Lindholm, Daniel; Gustafsson, Stefan et al.

Part of Vascular Medicine, p. 300-300, 2018

Clinical and Genetic Determinants of Varicose Veins Prospective, Community-Based Study of approximate to 500 000 Individuals

Fukaya, Eri; Flores, Alyssa M.; Lindholm, Daniel P; Gustafsson, Stefan et al.

Part of Circulation, p. 2869-2880, 2018

• DOI for Clinical and Genetic Determinants of Varicose Veins Prospective, Community-Based Study of approximate to 500 000 Individuals

Use of Proteomics to Investigate Blood Pressure Progress in the Elderly

Yi-Ting, Lin; Fall, Tove; Gustafsson, Stefan; Ingelsson, Erik et al.

Part of Journal of Hypertension, 2018

• DOI for Use of Proteomics to Investigate Blood Pressure Progress in the Elderly

Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank

Tikkanen, Emmi; Gustafsson, Stefan; Amar, David; Shcherbina, Anna et al.

Part of Scientific Reports, 2018

• DOI for Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank
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Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Mahajan, Anubha; Wessel, Jennifer; Willems, Sara M.; Zhao, Wei et al.

Part of Nature Genetics, p. 559-571, 2018

• DOI for Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

Malik, Rainer; Chauhan, Ganesh; Traylor, Matthew; Sargurupremraj, Muralidharan et al.

Part of Nature Genetics, p. 524-537, 2018

• DOI for Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

Birthweight, Type 2 Diabetes Mellitus, and Cardiovascular Disease Addressing the Barker Hypothesis With Mendelian Randomization

Zanetti, Daniela; Tikkanen, Emmi; Gustafsson, Stefan; Priest, James R. et al.

Part of Circulation, 2018

• DOI for Birthweight, Type 2 Diabetes Mellitus, and Cardiovascular Disease Addressing the Barker Hypothesis With Mendelian Randomization
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Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development

Nielsen, Jonas B.; Fritsche, Lars G.; Zhou, Wei; Teslovich, Tanya M. et al.

Part of American Journal of Human Genetics, p. 103-115, 2018

• DOI for Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development

A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relationship to chronic lymphocytic leukemia

Chen, Xu; Gustafsson, Stefan; Whitington, Thomas; Borne, Yan et al.

Part of Human Molecular Genetics, p. 1809-1818, 2018

• DOI for A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relationship to chronic lymphocytic leukemia

Multi-ethnic genome-wide association study for atrial fibrillation

Roselli, Carolina; Chaffin, Mark D.; Weng, Lu-Chen; Aeschbacher, Stefanie et al.

Part of Nature Genetics, p. 1225-1233, 2018

• DOI for Multi-ethnic genome-wide association study for atrial fibrillation

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Turcot, Valerie; Lu, Yingchang; Highland, Heather M.; Schurmann, Claudia et al.

Part of Nature Genetics, p. 26-+, 2018

• DOI for Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank

Fall, Tove; Gustafsson, Stefan; Orho-Melander, Marju; Ingelsson, Erik

Part of Diabetologia, p. 2174-2179, 2018

• DOI for Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank
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A DNA methylation biomarker of alcohol consumption.

Liu, C; Marioni, R E; Hedman, Åsa K; Pfeiffer, L et al.

Part of Molecular Psychiatry, p. 422-433, 2018

• DOI for A DNA methylation biomarker of alcohol consumption.
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Role of peroxisome proliferator-activated receptor gamma Pro12Ala polymorphism in human adipose tissue: assessment of adipogenesis and adipocyte glucose and lipid turnover.

Kamble, Prasad G.; Pereira, Maria J; Gustafsson, Stefan; Lundkvist, Per et al.

Part of Adipocyte, p. 285-296, 2018

• DOI for Role of peroxisome proliferator-activated receptor gamma Pro12Ala polymorphism in human adipose tissue: assessment of adipogenesis and adipocyte glucose and lipid turnover.
• Download full text (pdf) of Role of peroxisome proliferator-activated receptor gamma Pro12Ala polymorphism in human adipose tissue: assessment of adipogenesis and adipocyte glucose and lipid turnover.

Targeted proteomic analysis of habitual coffee consumption.

Cornelis, M C; Gustafsson, Stefan; Ärnlöv, J; Elmståhl, S et al.

Part of Journal of Internal Medicine, p. 200-211, 2018

• DOI for Targeted proteomic analysis of habitual coffee consumption.

Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach

Mendelson, Michael M.; Marioni, Riccardo E.; Joehanes, Roby; Liu, Chunyu et al.

Part of PLoS Medicine, 2017

• DOI for Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach
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Use of Proteomics To Investigate Kidney Function Decline over 5 Years

Carlsson, Axel C; Ingelsson, Erik; Sundström, Johan; Carrero, Juan Jesus et al.

Part of American Society of Nephrology. Clinical Journal, p. 1226-1235, 2017

• DOI for Use of Proteomics To Investigate Kidney Function Decline over 5 Years

Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation

Strawbridge, Rona J.; Silveira, Angela; den Hoed, Marcel; Gustafsson, Stefan et al.

Part of Atherosclerosis, p. 196-204, 2017

• DOI for Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation
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Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies

Hedman, Åsa K.; Mendelson, Michael M.; Marioni, Riccardo E.; Gustafsson, Stefan et al.

Part of Circulation, 2017

• DOI for Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies
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Genotype-based recall to study metabolic effects of genetic variation: a pilot study of PPARG Pro12Ala carriers

Kamble, Prasad G.; Gustafsson, Stefan; Pereira, Maria J; Lundkvist, Per et al.

Part of Upsala Journal of Medical Sciences, p. 234-242, 2017

• DOI for Genotype-based recall to study metabolic effects of genetic variation: a pilot study of PPARG Pro12Ala carriers
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Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

Christophersen, Ingrid E.; Rienstra, Michiel; Roselli, Carolina; Yin, Xiaoyan et al.

Part of Nature Genetics, p. 946-+, 2017

• DOI for Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

Rare and low-frequency coding variants alter human adult height

Marouli, Eirini; Graff, Mariaelisa; Medina-Gomez, Carolina; Lo, Ken Sin et al.

Part of Nature, p. 186-190, 2017

• DOI for Rare and low-frequency coding variants alter human adult height

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

Scott, Robert A.; Scott, Laura J.; Maegi, Reedik; Marullo, Letizia et al.

Part of Diabetes, p. 2888-2902, 2017

• DOI for An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease

Folkersen, Lasse; Fauman, Eric; Sabater-Lleal, Maria; Strawbridge, Rona J et al.

Part of PLOS Genetics, 2017

• DOI for Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease
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Use of a proximity extension assay proteomics chip to discover new biomarkers associated with albuminuria

Carlsson, Axel C.; Sundström, Johan; Carrero, Juan Jesus; Gustafsson, Stefan et al.

Part of European Journal of Preventive Cardiology, p. 340-348, 2017

• DOI for Use of a proximity extension assay proteomics chip to discover new biomarkers associated with albuminuria

PPARG Pro12Ala variant in relation to adipose tissue metabolism and differentiation: a small genotype-based recall study

Kamble, Prasad G.; Pereira, Maria J; Gustafsson, Stefan; Lundkvist, Per et al.

Part of Diabetologia, 2017

Novel genetic loci associated with long-term deterioration in blood lipid concentrations and coronary artery disease in European adults

Varga, Tibor V.; Kurbasic, Azra; Aine, Mattias; Eriksson, Pontus et al.

Part of International Journal of Epidemiology, p. 1211-1222, 2017

• DOI for Novel genetic loci associated with long-term deterioration in blood lipid concentrations and coronary artery disease in European adults

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

Schmidt, Amand F.; Swerdlow, Daniel I.; Holmes, Michael V.; Patel, Riyaz S. et al.

Part of The Lancet Diabetes and Endocrinology, p. 97-105, 2017

• DOI for PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study
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New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

Lu, Yingchang; Day, Felix R; Gustafsson, Stefan; Buchkovich, Martin L et al.

Part of Nature Communications, 2016

• DOI for New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
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Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior

Cornelis, Marilyn C; Kacprowski, Tim; Menni, Cristina; Gustafsson, Stefan et al.

Part of Human Molecular Genetics, p. 5472-5482, 2016

• DOI for Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis

Loley, Christina; Alver, Maris; Assimes, Themistocles L.; Bjonnes, Andrew et al.

Part of Scientific Reports, 2016

• DOI for No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis
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Genome-wide DNA methylation study identifies genes associated with the cardiovascular biomarker GDF-15

Ek, Weronica E; Hedman, Åsa K; Enroth, Stefan; Morris, Andrew P et al.

Part of Human Molecular Genetics, p. 817-827, 2016

• DOI for Genome-wide DNA methylation study identifies genes associated with the cardiovascular biomarker GDF-15

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

Kilpeläinen, Tuomas O; Carli, Jayne F Martin; Skowronski, Alicja A; Sun, Qi et al.

Part of Nature Communications, 2016

• DOI for Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels
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Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci

Walford, Geoffrey A.; Gustafsson, Stefan; Rybin, Denis; Stancakova, Alena et al.

Part of Diabetes, p. 3200-3211, 2016

• DOI for Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci

Non-targeted metabolomics combined with genetic analyses identifies bile acid synthesis and phospholipid metabolism as being associated with incident type 2 diabetes

Fall, Tove; Salihovic, Samira; Brandmaier, Stefan; Nowak, Christoph et al.

Part of Diabetologia, p. 2114-2124, 2016

• DOI for Non-targeted metabolomics combined with genetic analyses identifies bile acid synthesis and phospholipid metabolism as being associated with incident type 2 diabetes

Protein Biomarkers for Insulin Resistance and Type 2 Diabetes Risk in Two Large Community Cohorts

Nowak, Christoph; Sundström, Johan; Gustafsson, Stefan; Giedraitis, Vilmantas et al.

Part of Diabetes, p. 276-284, 2016

• DOI for Protein Biomarkers for Insulin Resistance and Type 2 Diabetes Risk in Two Large Community Cohorts

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

Winkler, Thomas W.; Justice, Anne E.; Graff, Mariaelisa; Barata, Llilda et al.

Part of PLOS Genetics, 2015

• DOI for The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
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Population genetic differentiation of height and body mass index across Europe

Robinson, Matthew R.; Hemani, Gibran; Medina-Gomez, Carolina; Mezzavilla, Massimo et al.

Part of Nature Genetics, p. 1357-1362, 2015

• DOI for Population genetic differentiation of height and body mass index across Europe

GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb

den Hoed, Marcel; Strawbridge, Rona J; Almgren, Peter; Gustafsson, Stefan et al.

Part of Atherosclerosis, p. 304-310, 2015

• DOI for GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb

Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease

Persson, Jonas; Strawbridge, Rona J.; McLeod, Olga; Gertow, Karl et al.

Part of Journal of the American Heart Association, 2015

• DOI for Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease
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A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

Nikpay, Majid; Goel, Anuj; Won, Hong-Hee; Hall, Leanne M. et al.

Part of Nature Genetics, p. 1121-1130, 2015

• DOI for A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

The impact of low-frequency and rare variants on lipid levels

Surakka, Ida; Horikoshi, Momoko; Magi, Reedik; Sarin, Antti-Pekka et al.

Part of Nature Genetics, p. 589-597, 2015

• DOI for The impact of low-frequency and rare variants on lipid levels

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Gaulton, Kyle J.; Ferreira, Teresa; Lee, Yeji; Raimondo, Anne et al.

Part of Nature Genetics, p. 1415, 2015

• DOI for Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Biological interpretation of genome-wide association studies using predicted gene functions

Pers, Tune H.; Karjalainen, Juha M.; Chan, Yingleong; Westra, Harm-Jan et al.

Part of Nature Communications, 2015

• DOI for Biological interpretation of genome-wide association studies using predicted gene functions

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

Wessel, Jennifer; Chu, Audrey Y.; Willems, Sara M.; Wang, Shuai et al.

Part of Nature Communications, 2015

• DOI for Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

New genetic loci link adipose and insulin biology to body fat distribution

Shungin, Dmitry; Winkler, Thomas W; Croteau-Chonka, Damien C; Ferreira, Teresa et al.

Part of Nature, p. 187-196, 2015

• DOI for New genetic loci link adipose and insulin biology to body fat distribution

Genetic studies of body mass index yield new insights for obesity biology

Locke, Adam E; Kahali, Bratati; Berndt, Sonja I; Justice, Anne E et al.

Part of Nature, p. 197-206, 2015

• DOI for Genetic studies of body mass index yield new insights for obesity biology

Mendelian randomization study of height and risk of colorectal cancer

Thrift, Aaron P.; Gong, Jian; Peters, Ulrike; Chang-Claude, Jenny et al.

Part of International Journal of Epidemiology, p. 662-672, 2015

• DOI for Mendelian randomization study of height and risk of colorectal cancer

Defining the role of common variation in the genomic and biological architecture of adult human height

Wood, Andrew R; Esko, Tonu; Yang, Jian; Vedantam, Sailaja et al.

Part of Nature Genetics, p. 1173-1186, 2014

• DOI for Defining the role of common variation in the genomic and biological architecture of adult human height

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Arking, Dan E; Pulit, Sara L; Crotti, Lia; van der Harst, Pim et al.

Part of Nature Genetics, p. 826-836, 2014

• DOI for Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Quality control and conduct of genome-wide association meta-analyses

Winkler, Thomas W.; Day, Felix R.; Croteau-Chonka, Damien C.; Wood, Andrew R. et al.

Part of Nature Protocols, p. 1192-1212, 2014

• DOI for Quality control and conduct of genome-wide association meta-analyses

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Berndt, Sonja I.; Gustafsson, Stefan; Maegi, Reedik; Ganna, Andrea et al.

Part of Nature Genetics, p. 501-U69, 2013

• DOI for Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
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Discovery and refinement of loci associated with lipid levels

Willer, Cristen J.; Schmidt, Ellen M.; Sengupta, Sebanti; Peloso, Gina M. et al.

Part of Nature Genetics, p. 1274-1283, 2013

• DOI for Discovery and refinement of loci associated with lipid levels

Common variants associated with plasma triglycerides and risk for coronary artery disease

Do, Ron; Willer, Cristen J.; Schmidt, Ellen M.; Sengupta, Sebanti et al.

Part of Nature Genetics, p. 1345-+, 2013

• DOI for Common variants associated with plasma triglycerides and risk for coronary artery disease

Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes

Yaghootkar, Hanieh; Lamina, Claudia; Scott, Robert A.; Dastani, Zari et al.

Part of Diabetes, p. 3589-3598, 2013

• DOI for Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes

Meta-analysis of Gene-Level Associations for Rare Variants Based on Single-Variant Statistics

Hu, Yi-Juan; Berndt, Sonja I.; Gustafsson, Stefan; Ganna, Andrea et al.

Part of American Journal of Human Genetics, p. 236-248, 2013

• DOI for Meta-analysis of Gene-Level Associations for Rare Variants Based on Single-Variant Statistics

Discovery and replication of new risk markers for 5-year kidney function decline using a targeted multiplex proteomics chip

Ärnlöv, Johan; Ingelsson, Erik; Sundström, Johan; Carrero, J. J. et al.

p. 350-350, 2016