Leandro Simonetti

Exploring the short linear motif-mediated protein-protein interactions of CrkL through ProP-PD

Pagano, L.; Simonetti, Leandro; Pennacchietti, V.; Toto, A. et al.

Part of Biochemical and Biophysical Research Communications - BBRC, 2024

• DOI for Exploring the short linear motif-mediated protein-protein interactions of CrkL through ProP-PD

Proteome-scale characterisation of motif-based interactome rewiring by disease mutations

Kliche, Johanna; Simonetti, Leandro; Krystkowiak, Izabella; Kuss, Hanna et al.

Part of Molecular Systems Biology, p. 1025-1048, 2024

• DOI for Proteome-scale characterisation of motif-based interactome rewiring by disease mutations
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ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers

Zhang, Yi; Xie, Guojia; Lee, Ji-Eun; Zandian, Mohamad et al.

Part of Nature Communications, 2024

• DOI for ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers
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Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs

Mihalič, Filip; Simonetti, Leandro; Giudice, Girolamo; Rubin Sander, Marie et al.

Part of Nature Communications, 2023

• DOI for Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs
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The next wave of interactomics: Mapping the SLiM-based interactions of the intrinsically disordered proteome

Davey, Norman E.; Simonetti, Leandro; Ivarsson, Ylva

Part of Current opinion in structural biology, 2023

• DOI for The next wave of interactomics: Mapping the SLiM-based interactions of the intrinsically disordered proteome
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Exploring the short linear motif-mediated protein-protein interactions of CrkL through ProP-PD

Pagano, L.; Simonetti, Leandro; Pennacchietti, V.; Toto, A. et al.

Part of Biochemical and Biophysical Research Communications - BBRC, 2024

• DOI for Exploring the short linear motif-mediated protein-protein interactions of CrkL through ProP-PD

Proteome-scale characterisation of motif-based interactome rewiring by disease mutations

Kliche, Johanna; Simonetti, Leandro; Krystkowiak, Izabella; Kuss, Hanna et al.

Part of Molecular Systems Biology, p. 1025-1048, 2024

• DOI for Proteome-scale characterisation of motif-based interactome rewiring by disease mutations
• Download full text (pdf) of Proteome-scale characterisation of motif-based interactome rewiring by disease mutations

ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers

Zhang, Yi; Xie, Guojia; Lee, Ji-Eun; Zandian, Mohamad et al.

Part of Nature Communications, 2024

• DOI for ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers
• Download full text (pdf) of ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers

Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs

Mihalič, Filip; Simonetti, Leandro; Giudice, Girolamo; Rubin Sander, Marie et al.

Part of Nature Communications, 2023

• DOI for Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs
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The next wave of interactomics: Mapping the SLiM-based interactions of the intrinsically disordered proteome

Davey, Norman E.; Simonetti, Leandro; Ivarsson, Ylva

Part of Current opinion in structural biology, 2023

• DOI for The next wave of interactomics: Mapping the SLiM-based interactions of the intrinsically disordered proteome
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Presenting technological workflows

Sanchez, M. Florencia; Iselin, Louisa; Simonetti, Leandro

Part of TIBS -Trends in Biochemical Sciences. Regular ed., p. 587-589, 2023

• DOI for Presenting technological workflows

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets

Mihalic, Filip; Benz, Caroline; Kassa, Eszter; Lindqvist, Richard et al.

Part of Nature Communications, 2023

• DOI for Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets
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Evaluation of affinity-purification coupled to mass spectrometry approaches for capture of short linear motif-based interactions

Kassa, Eszter; Jamshidi, Sara; Mihalič, Filip; Simonetti, Leandro et al.

Part of Analytical Biochemistry, 2023

• DOI for Evaluation of affinity-purification coupled to mass spectrometry approaches for capture of short linear motif-based interactions
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Proteome-scale mapping of binding sites in the unstructured regions of the human proteome

Benz, Caroline; Ali, Muhammad; Krystkowiak, Izabella; Simonetti, Leandro et al.

Part of Molecular Systems Biology, 2022

• DOI for Proteome-scale mapping of binding sites in the unstructured regions of the human proteome
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ProP-PD for proteome-wide motif-mediated interaction discovery

Davey, Norman E.; Simonetti, Leandro; Ivarsson, Ylva

Part of TIBS -Trends in Biochemical Sciences. Regular ed., p. 547-548, 2022

• DOI for ProP-PD for proteome-wide motif-mediated interaction discovery
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Recombinant antibody against Trypanosoma cruzi from patients with chronic Chagas heart disease recognizes mammalian nervous system

Niborski, Leticia L.; Potenza, Mariana; Chirivi, Renato G. S.; Simonetti, Leandro et al.

Part of EBioMedicine, 2021

• DOI for Recombinant antibody against Trypanosoma cruzi from patients with chronic Chagas heart disease recognizes mammalian nervous system
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Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

Kruse, Thomas; Benz, Caroline; Garvanska, Dimitriya H.; Lindqvist, Richard et al.

Part of Nature Communications, 2021

• DOI for Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities
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Genetically Encoded Cyclic Peptide Phage Display Libraries

Simonetti, Leandro; Ivarsson, Ylva

Part of ACS CENTRAL SCIENCE, p. 336-338, 2020

• DOI for Genetically Encoded Cyclic Peptide Phage Display Libraries
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An update on genetic variants of the NKX2-5

Kolomenski, Jorge E.; Delea, Marisol; Simonetti, Leandro; Fabbro, Monica C. et al.

Part of Human Mutation, p. 1187-1208, 2020

• DOI for An update on genetic variants of the NKX2-5

SLiM-binding pockets: an attractive target for broad-spectrum antivirals

Simonetti, Leandro; Nilsson, Jakob; McInerney, Gerald; Ivarsson, Ylva et al.

Part of TIBS -Trends in Biochemical Sciences. Regular ed., p. 420-427, 2023

• DOI for SLiM-binding pockets: an attractive target for broad-spectrum antivirals
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Evaluation of affinity-purification coupled to mass spectrometry approaches for capture of short linear motif-based interactions

Kassa, Eszter; Jamshidi, Sara; Mihalič, Filip; Simonetti, Leandro et al.

• DOI for Evaluation of affinity-purification coupled to mass spectrometry approaches for capture of short linear motif-based interactions