Fariborz Mobarrez
Senior Lecturer/Associate Professor at Department of Medical Sciences; Clinical Chemistry
- E-mail:
- fariborz.mobarrez@medsci.uu.se
- Visiting address:
- Akademiska sjukhuset, ingång 61, 3 tr
- Postal address:
- Akademiska sjukhuset, ingång 61
751 85 Uppsala
Short presentation
Associate Professor in Experimental Clinical Chemistry and Senior Lecturer in Biomedical Laboratory Science. Program Director of the Master’s Programme in Biomedical Laboratory Science.
Keywords
- Hematology
- flow cytometry
- autoimmunity
- cardiovascular diseases
- extracellular vesicles
- rheumatology
- microvesicles
- microparticles
Research
I am a Senior Lecturer at the Department of Medical Sciences, Uppsala University, with a joint appointment at Uppsala University Hospital in Clinical Chemistry, and I am an Associate Professor in Experimental Clinical Chemistry. My research focuses on extracellular vesicles (EVs) as circulating biomarkers in inflammation, barrier dysfunction, and systemic disease, with an emphasis on method development and clinical translation. A central part of my work is the development of flow cytometry–based methods for EV analysis in frozen plasma, enabling retrospective studies and providing a platform for broad collaborations.
My research spans thrombosis and vascular biology (including endothelial- and platelet-derived EVs in cardiovascular disease and coagulation disorders), immunomedicine (e.g., SLE and vasculitis), and neuroinflammation and blood–brain barrier involvement in stress-related exhaustion and post-COVID. In recent years, I have also developed tissue-specific EV analyses, including brain- and lung-derived vesicles, and im involved in translational projects in paediatric oncology, gynaecological oncology, and environmental and airway exposures. I have published original research in the field and actively participate in externally funded collaborations and the supervision of clinical PhD students, with the overarching goal of standardising EV analysis and bringing EV-based diagnostics closer to clinical implementation.

Publications
Recent publications
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Part of Frontiers in Pediatrics, 2026
- DOI for Exploratory analysis of neutrophil extracellular traps in synovial fluid and plasma from children with juvenile idiopathic arthritis
- Download full text (pdf) of Exploratory analysis of neutrophil extracellular traps in synovial fluid and plasma from children with juvenile idiopathic arthritis
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Part of Schizophrenia Research, p. 195-203, 2025
- DOI for Aquaporin-4 positive extracellular vesicles and cytokines in cerebrospinal fluid in schizophrenia and obsessive-compulsive disorder, and associations with peripheral cytokines
- Download full text (pdf) of Aquaporin-4 positive extracellular vesicles and cytokines in cerebrospinal fluid in schizophrenia and obsessive-compulsive disorder, and associations with peripheral cytokines
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Part of Upsala Journal of Medical Sciences, 2025
- DOI for Elevated levels of aquaporin-4-containing extracellular vesicles in cerebrospinal fluid of patients with bipolar disorder
- Download full text (pdf) of Elevated levels of aquaporin-4-containing extracellular vesicles in cerebrospinal fluid of patients with bipolar disorder
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Nicotine in E-cigarette aerosol may lead to pulmonary inflammation
Part of Respiratory Medicine, 2025
- DOI for Nicotine in E-cigarette aerosol may lead to pulmonary inflammation
- Download full text (pdf) of Nicotine in E-cigarette aerosol may lead to pulmonary inflammation
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Extracellular vesicle release in an experimental ventilator-induced lung injury porcine model
Part of PLOS ONE, 2025
- DOI for Extracellular vesicle release in an experimental ventilator-induced lung injury porcine model
- Download full text (pdf) of Extracellular vesicle release in an experimental ventilator-induced lung injury porcine model
All publications
Articles in journal
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Part of Frontiers in Pediatrics, 2026
- DOI for Exploratory analysis of neutrophil extracellular traps in synovial fluid and plasma from children with juvenile idiopathic arthritis
- Download full text (pdf) of Exploratory analysis of neutrophil extracellular traps in synovial fluid and plasma from children with juvenile idiopathic arthritis
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Part of Schizophrenia Research, p. 195-203, 2025
- DOI for Aquaporin-4 positive extracellular vesicles and cytokines in cerebrospinal fluid in schizophrenia and obsessive-compulsive disorder, and associations with peripheral cytokines
- Download full text (pdf) of Aquaporin-4 positive extracellular vesicles and cytokines in cerebrospinal fluid in schizophrenia and obsessive-compulsive disorder, and associations with peripheral cytokines
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Part of Upsala Journal of Medical Sciences, 2025
- DOI for Elevated levels of aquaporin-4-containing extracellular vesicles in cerebrospinal fluid of patients with bipolar disorder
- Download full text (pdf) of Elevated levels of aquaporin-4-containing extracellular vesicles in cerebrospinal fluid of patients with bipolar disorder
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Nicotine in E-cigarette aerosol may lead to pulmonary inflammation
Part of Respiratory Medicine, 2025
- DOI for Nicotine in E-cigarette aerosol may lead to pulmonary inflammation
- Download full text (pdf) of Nicotine in E-cigarette aerosol may lead to pulmonary inflammation
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Extracellular vesicle release in an experimental ventilator-induced lung injury porcine model
Part of PLOS ONE, 2025
- DOI for Extracellular vesicle release in an experimental ventilator-induced lung injury porcine model
- Download full text (pdf) of Extracellular vesicle release in an experimental ventilator-induced lung injury porcine model
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Part of Cardiovascular Toxicology, p. 1-8, 2025
- DOI for Vascular Stress Markers Following Inhalation of Heated Tobacco Products: A Study on Extracellular Vesicles
- Download full text (pdf) of Vascular Stress Markers Following Inhalation of Heated Tobacco Products: A Study on Extracellular Vesicles
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Oneyear longitudinal study on biomarkers of blood-brain barrier permeability in COVID-19 patients
Part of Scientific Reports, 2024
- DOI for Oneyear longitudinal study on biomarkers of blood-brain barrier permeability in COVID-19 patients
- Download full text (pdf) of Oneyear longitudinal study on biomarkers of blood-brain barrier permeability in COVID-19 patients
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Part of Pediatric Rheumatology, 2024
- DOI for Blood brain barrier permeability and astrocyte-derived extracellular vesicles in children with juvenile idiopathic arthritis: a cross-sectional study
- Download full text (pdf) of Blood brain barrier permeability and astrocyte-derived extracellular vesicles in children with juvenile idiopathic arthritis: a cross-sectional study
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Part of Journal of Autoimmunity, 2023
- DOI for Extracellular vesicles opsonized by monomeric C-reactive protein (CRP) are accessible as autoantigens in patients with systemic lupus erythematosus and associate with autoantibodies against CRP
- Download full text (pdf) of Extracellular vesicles opsonized by monomeric C-reactive protein (CRP) are accessible as autoantigens in patients with systemic lupus erythematosus and associate with autoantibodies against CRP
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Part of Frontiers in Medicine, 2023
- DOI for Augmented thrombin formation is related to circulating levels of extracellular vesicles exposing tissue factor and citrullinated histone-3 in anti-neutrophil cytoplasmic antibody-associated vasculitides
- Download full text (pdf) of Augmented thrombin formation is related to circulating levels of extracellular vesicles exposing tissue factor and citrullinated histone-3 in anti-neutrophil cytoplasmic antibody-associated vasculitides
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Part of Cardiovascular Toxicology, p. 255-264, 2023
- DOI for Electronic Cigarette Vaping with Nicotine Causes Increased Thrombogenicity and Impaired Microvascular Function in Healthy Volunteers: A Randomised Clinical Trial
- Download full text (pdf) of Electronic Cigarette Vaping with Nicotine Causes Increased Thrombogenicity and Impaired Microvascular Function in Healthy Volunteers: A Randomised Clinical Trial
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Part of Frontiers in Cardiovascular Medicine, 2022
- DOI for Extracellular vesicles in heart failure: A study in patients with heart failure with preserved ejection fraction or heart failure with reduced ejection fraction characteristics undergoing elective coronary artery bypass grafting
- Download full text (pdf) of Extracellular vesicles in heart failure: A study in patients with heart failure with preserved ejection fraction or heart failure with reduced ejection fraction characteristics undergoing elective coronary artery bypass grafting
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Plasma levels of S100B and neurofilament light chain protein in stress-related mental disorders
Part of Scientific Reports, 2022
- DOI for Plasma levels of S100B and neurofilament light chain protein in stress-related mental disorders
- Download full text (pdf) of Plasma levels of S100B and neurofilament light chain protein in stress-related mental disorders
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Phosphatidylserine Exposing Extracellular Vesicles in Pre-eclamptic Patients
Part of Frontiers in Medicine, 2021
- DOI for Phosphatidylserine Exposing Extracellular Vesicles in Pre-eclamptic Patients
- Download full text (pdf) of Phosphatidylserine Exposing Extracellular Vesicles in Pre-eclamptic Patients
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Part of Thrombosis and Haemostasis, p. 584-593, 2021
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Part of Scientific Reports, 2021
- DOI for Leakage of astrocyte-derived extracellular vesicles in stress-induced exhaustion disorder: a cross-sectional study
- Download full text (pdf) of Leakage of astrocyte-derived extracellular vesicles in stress-induced exhaustion disorder: a cross-sectional study
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Part of Scientific Reports, 2021
- DOI for Isoforms of soluble vascular endothelial growth factor in stress-related mental disorders: a cross-sectional study
- Download full text (pdf) of Isoforms of soluble vascular endothelial growth factor in stress-related mental disorders: a cross-sectional study
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Part of Journal of Rheumatology, p. 714-721, 2020
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Part of Journal of Molecular Medicine, p. 1279-1286, 2020
- DOI for Microparticles expressing myeloperoxidase as potential biomarkers in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV)
- Download full text (pdf) of Microparticles expressing myeloperoxidase as potential biomarkers in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV)
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The binding of SLE autoantibodies to mitochondria
Part of Clinical Immunology, 2020
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Part of Scientific Reports, 2020
- DOI for Changes in the plasma microvesicle proteome during the ovarian hyperstimulation phase of assisted reproductive technology
- Download full text (pdf) of Changes in the plasma microvesicle proteome during the ovarian hyperstimulation phase of assisted reproductive technology
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Part of Journal of Thrombosis and Haemostasis, p. 1965-1973, 2020
- DOI for Incidence of pulmonary and venous thromboembolism in pregnancies after in vitro fertilization with fresh respectively frozen-thawed embryo transfer: Nationwide cohort study
- Download full text (pdf) of Incidence of pulmonary and venous thromboembolism in pregnancies after in vitro fertilization with fresh respectively frozen-thawed embryo transfer: Nationwide cohort study
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Part of Thrombosis Research, p. 78-86, 2020
- DOI for High levels of endothelial and platelet microvesicles in patients with type 1 diabetes irrespective of microvascular complications
- Download full text (pdf) of High levels of endothelial and platelet microvesicles in patients with type 1 diabetes irrespective of microvascular complications
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Phosphatidylserine positive microparticles improve hemostasis in in-vitro hemophilia A plasma models
Part of Scientific Reports, 2020
- DOI for Phosphatidylserine positive microparticles improve hemostasis in in-vitro hemophilia A plasma models
- Download full text (pdf) of Phosphatidylserine positive microparticles improve hemostasis in in-vitro hemophilia A plasma models
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Prognostic Value of Circulating Microvesicle Subpopulations in Ischemic Stroke and TIA
Part of Translational Stroke Research, p. 708-719, 2020
- DOI for Prognostic Value of Circulating Microvesicle Subpopulations in Ischemic Stroke and TIA
- Download full text (pdf) of Prognostic Value of Circulating Microvesicle Subpopulations in Ischemic Stroke and TIA
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Part of Atherosclerosis, p. 93-100, 2020
- DOI for Electronic cigarettes containing nicotine increase endothelial and platelet derived extracellular vesicles in healthy volunteers
- Download full text (pdf) of Electronic cigarettes containing nicotine increase endothelial and platelet derived extracellular vesicles in healthy volunteers
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Part of Journal of Autoimmunity, p. 142-149, 2019
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Part of Frontiers in Immunology, 2019
- DOI for Circulating Levels of Interferon Regulatory Factor-5 Associates With Subgroups of Systemic Lupus Erythematosus Patients.
- Download full text (pdf) of Circulating Levels of Interferon Regulatory Factor-5 Associates With Subgroups of Systemic Lupus Erythematosus Patients.
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Microvesicles from patients with acute coronary syndrome enhance platelet aggregation
Part of Scandinavian Journal of Clinical and Laboratory Investigation, p. 507-512, 2019
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Part of Platelets, p. 348-355, 2019
- DOI for Meal intake increases circulating procoagulant microparticles in patients with type 1 and type 2 diabetes mellitus
- Download full text (pdf) of Meal intake increases circulating procoagulant microparticles in patients with type 1 and type 2 diabetes mellitus
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A multicolor flow cytometric assay for measurement of platelet-derived microparticles
Part of Thrombosis Research, 2010