Eva Freyhult

Inflammatory protein profiles and shunt response in iNPH

Braun, Madelen; Ekblom, Maria; Freyhult, Eva; Åberg, Mikael et al.

Part of Fluids and Barriers of the CNS, 2026

Pre-diagnostic and diagnostic D-vitamin levels and risk of bladder cancer: A nested case-control study with follow-up at diagnosis

Hultdin, Johan; Tellström, Andreas; Freyhult, Eva; Landström, Maréne et al.

Part of Clinical Nutrition Open Science, 2026

DOI for Pre-diagnostic and diagnostic D-vitamin levels and risk of bladder cancer: A nested case-control study with follow-up at diagnosis
Download full text (pdf) of Pre-diagnostic and diagnostic D-vitamin levels and risk of bladder cancer: A nested case-control study with follow-up at diagnosis

Exploratory study linking plasma proteomics to cardiotoxicity in Hodgkin lymphoma

Mattson Ulfstedt, Johan; Risebro, Ragnhild; Freyhult, Eva; Christersson, Christina et al.

Part of Cardio-Oncology, 2026

Co-exposure to PFAS and hydroxylated PCBs is associated with increased odds of multiple sclerosis

Vaivade, Aina; Parakkal Sreenivasan, Akshai; Erngren, Ida; Freyhult, Eva et al.

Part of Environment International, 2026

Targeted CSF metabolomics and conformal prediction improve diagnostic accuracy of normal pressure hydrocephalus

Hofling, Ulrika; Jakobsson, Jenny; Erngren, Ida; Ekman, Oskar et al.

Part of Fluids and Barriers of the CNS, 2026

Associations of PFAS and OH-PCBs with risk of multiple sclerosis onset and disability worsening

Vaivade, Aina; Erngren, Ida; Carlsson, Henrik; Freyhult, Eva et al.

Part of Nature Communications, 2025

Fibromyalgia patients have altered lipid concentrations associated with disease symptom severity and anti-satellite glial cell IgG antibodies

Jakobsson, Jenny; Menezes, Joana; Krock, Emerson; Hunt, Matthew A. et al.

Part of Journal of Pain, 2025

Uncemented hip arthroplasty and denosumab: increased postoperative dipeptide concentrations and identification of potential new bone turnover biomarkers

Kultima, Kim; Hosseini Ashtiani, Saman; Erngren, Ida; Emami Khoonsari, Payam et al.

Part of JBMR Plus, 2025

Dynamics of the blood plasma proteome during hyperacute HIV-1 infection

Nazziwa, Jamirah; Freyhult, Eva; Hong, Mun-Gwan; Johansson, Emil et al.

Part of Nature Communications, 2024

Treatment of Periprosthetic Joint Infection with Intravenous Vancomycin: Do We Hit the Target?

Haglund, Rasmus; Tornberg, Ulrika; Claesson, Ann-Charlotte; Freyhult, Eva et al.

Part of Antibiotics, 2024

HIV-2 mediated effects on target and bystander cells induce plasma proteome remodeling

Johansson, Emil; Nazziwa, Jamirah; Freyhult, Eva; Hong, Mun-Gwan et al.

Part of iScience, 2024

Childhood screening for type 1 diabetes comparing automated multiplex Antibody Detection by Agglutination-PCR (ADAP) with single plex islet autoantibody radiobinding assays

Lind, Alexander; Freyhult, Eva; de Jesus Cortez, Felipe; Ramelius, Anita et al.

Part of EBioMedicine, 2024

Levels of inflammatory cytokines MCP-1, CCL4, and PD-L1 in CSF differentiate idiopathic normal pressure hydrocephalus from neurodegenerative diseases

Braun, Madelen; Boström, Gustaf; Ingelsson, Martin; Kilander, Lena et al.

Part of Fluids and Barriers of the CNS, 2023

Cerebrospinal fluid cytokines after autologous haematopoietic stem cell transplantation and intrathecal rituximab treatment for multiple sclerosis

Burman, Joachim; Zhukovskaja, Christina; Svenningsson, Anders; Freyhult, Eva et al.

Part of Brain Communications, 2023

Ki67 and prostate specific antigen are prognostic in metastatic hormone naïve prostate cancer

Spyratou, Vasiliki; Freyhult, Eva; Bergh, Anders; Thellenberg-Karlsson, Camilla et al.

Part of Acta Oncologica, p. 1698-1706, 2023

Single-Cell RNA Analysis Reveals Cell-Intrinsic Functions of CAR T Cells Correlating with Response in a Phase II Study of Lymphoma Patients

Sarén, Tina; Ramachandran, Mohanraj; Gammelgård, Gustav; Lövgren, Tanja et al.

Part of Clinical Cancer Research, p. 4139-4152, 2023

Strict self-isolation did not protect Swedish cancer patients on active treatment from the risk of becoming seropositive for SARS-CoV-2

Ginman, Beatrice; Pahnke, Simon; Freyhult, Eva; Hoffman, Tove et al.

Part of Acta Oncologica, p. 1707-1715, 2023

Autologous hematopoietic stem cell transplantation significantly alters circulating ceramides in peripheral blood of relapsing-remitting multiple sclerosis patients

Vaivade, Aina; Wiberg, Anna; Khoonsari, Payam Emami; Carlsson, Henrik et al.

Part of Lipids in Health and Disease, 2023

Higher levels of neurofilament light chain and total tau in CSF are associated with negative outcome after shunt surgery in patients with normal pressure hydrocephalus

Braun, Madelen; Bjurnemark, Caroline; Seo, Woosung; Freyhult, Eva et al.

Part of Fluids and Barriers of the CNS, 2022

Clinical and biological relevance of the transcriptomic-based prostate cancer metastasis subtypes MetA-C

Thysell, Elin; Köhn, Linda; Semenas, Julius; Järemo, Helena et al.

Part of Molecular Oncology, p. 846-859, 2022

Effects of denosumab treatment on the expression of receptor activator of nuclear kappa-B ligand (RANKL) and TNF-receptor TNFRSF9 after total hip arthroplasty-results from a randomized placebo-controlled clinical trial.

Sköld, Caroline; Kultima, Kim; Freyhult, Eva; Larsson, Anders et al.

Part of Osteoporosis International, p. 1-8, 2022

Reply to Carlos G. Wambier and Gerard J. Nau's Letter to the Editor re: Karin Welen, Ebba Rosendal, Magnus Gisslen, et al. A Phase 2 Trial of the Effect of Antiandrogen Therapy on COVID-19 Outcome: No Evidence of Benefit, Supported by Epidemiology and In Vitro Data. Eur Urol. 2022;81:285-93. Positive Effects of Enzalutamide for Hospitalized COVID-19 Patients

Welen, Karin; Rosendal, Ebba; Freyhult, Eva; Oh, William K. et al.

Part of European Urology, 2022

DOI for Reply to Carlos G. Wambier and Gerard J. Nau's Letter to the Editor re: Karin Welen, Ebba Rosendal, Magnus Gisslen, et al. A Phase 2 Trial of the Effect of Antiandrogen Therapy on COVID-19 Outcome: No Evidence of Benefit, Supported by Epidemiology and In Vitro Data. Eur Urol. 2022;81:285-93. Positive Effects of Enzalutamide for Hospitalized COVID-19 Patients

Re: Chen Dong, Sung-Lang Chen, and Wen-Wei Sung's Letter to the Editor re: Karin Welen, Ebba Rosendal, Magnus Gisslen, et al. A Phase 2 Trial of the Effect of Antiandrogen Therapy on COVID-19 Outcome: No Evidence of Benefit, Supported by Epidemiology and In Vitro Data. Eur Urol. 2022;81:285-93

Welen, Karin; Rosendal, Ebba; Freyhult, Eva; Connolly, Anne-Marie Fors et al.

Part of European Urology, 2022

DOI for Re: Chen Dong, Sung-Lang Chen, and Wen-Wei Sung's Letter to the Editor re: Karin Welen, Ebba Rosendal, Magnus Gisslen, et al. A Phase 2 Trial of the Effect of Antiandrogen Therapy on COVID-19 Outcome: No Evidence of Benefit, Supported by Epidemiology and In Vitro Data. Eur Urol. 2022;81:285-93

Cerebrospinal Fluid in Classical Trigeminal Neuralgia: An Exploratory Study on Candidate Biomarkers

Svedung-Wettervik, Teodor; Folkvaljon, Dick; Gordh, Torsten; Freyhult, Eva et al.

Part of Biomedicines, 2022

Distribution of five clinically important neuroglial proteins in the human brain.

Sjölin, Karl; Kultima, Kim; larsson, Anders; Freyhult, Eva et al.

Part of Molecular brain, 2022

White matter changes should not exclude patients with idiopathic normal pressure hydrocephalus from shunt surgery

Snöbohm, Carl; Malmberg, Filip; Freyhult, Eva; Kultima, Kim et al.

Part of Fluids and Barriers of the CNS, 2022

Osteoclasts directly influence castration-resistant prostate cancer cells

Huang, Junchi; Freyhult, Eva; Buckland, Robert; Josefsson, Andreas et al.

Part of Clinical and Experimental Metastasis, p. 801-814, 2022

Plasma protein biomarker profiling reveals major differences between acute leukaemia, lymphoma patients and controls

Sabaa, Amal Abu; Shen, Qiujin; Lennmyr, Emma; Enblad, Anna Pia et al.

Part of New Biotechnology, p. 21-29, 2022

Lysophophatidylcholine 16:0 mediates chronic joint pain associated to rheumatic diseases through acid-sensing ion channel 3

Jacquot, F.; Khoury, S.; Labrum, B.; Delanoe, K. et al.

Part of Pain, p. 1999-2013, 2022

Immune-Proteome Profiling in Classical Hodgkin Lymphoma Tumor Diagnostic Tissue

Gholiha, Alex R.; Hollander, Peter; Löf, Liza; Larsson, Anders et al.

Part of Cancers, 2022

Plasma proteome profiling of cardiotoxicity in patients with diffuse large B-cell lymphoma

Mörth, Charlott; Sabaa, Amal Abu; Freyhult, Eva; Christersson, Christina et al.

Part of Cardio-Oncology, 2021

Pulmonary fibrosis in relation to genetic loci in an inception cohort of patients with early rheumatoid arthritis from northern Sweden

Jönsson, Elias; Ljung, Lotta; Norrman, Eva; Freyhult, Eva et al.

Part of Rheumatology, p. 943-952, 2021

Metabolomics of Cerebrospinal Fluid from Healthy Subjects Reveal Metabolites Associated with Ageing

Carlsson, Henrik; Rollborn, Niclas; Herman, Stephanie; Freyhult, Eva et al.

Part of Metabolites, 2021

COVIDENZA - A prospective, multicenter, randomized PHASE II clinical trial of enzalutamide treatment to decrease the morbidity in patients with Corona virus disease 2019 (COVID-19): a structured summary of a study protocol for a randomised controlled trial

Welen, Karin; Overby, Anna K.; Ahlm, Clas; Freyhult, Eva et al.

Part of Trials, 2021

Toll-like receptor 4 methylation grade is linked to depressive symptom severity

Rasmusson, Annica J.; Gallwitz, Maike; Soltanabadi, Bardia; Ciuculete, Diana-Maria et al.

Part of Translational Psychiatry, 2021

Different Inflammatory Signatures in Alzheimer's Disease and Frontotemporal Dementia Cerebrospinal Fluid

Boström, Gustaf; Freyhult, Eva; Virhammar, Johan; Alcolea, Daniel et al.

Part of Journal of Alzheimer's Disease, p. 629-640, 2021

Elevated inflammatory proteins in cerebrospinal fluid from patients with painful knee osteoarthritis are associated with reduced symptom severity

Palada, Vinko; Ahmed, Aisha Siddiqah; Freyhult, Eva; Hugo, Anders et al.

Part of Journal of Neuroimmunology, 2020

Association between proteomics and obstructive sleep apnea phenotypes in a community-based cohort of women

Ljunggren, Mirjam; Theorell-Haglöw, Jenny; Freyhult, Eva; Sahlin, Carin et al.

Part of Journal of Sleep Research, 2020

Gene Expression Alterations during Development of Castration-Resistant Prostate Cancer Are Detected in Circulating Tumor Cells

Josefsson, Andreas; Larsson, Karin; Freyhult, Eva; Damber, Jan-Erik et al.

Part of Cancers, 2020

Comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'

Landegren, Nils; Rosen, Lindsey B.; Freyhult, Eva; Eriksson, Daniel et al.

Part of eLIFE, 2019

Anti-inflammatory drugs with more penetration into the central nervous system may contribute to the treatment of trigeminal neuralgia Reply

Ericson, Hans; Abu Hamdeh, Sami; Freyhult, Eva; Stiger, Fredrik et al.

Part of Pain, p. 2898-2899, 2019

DOI for Anti-inflammatory drugs with more penetration into the central nervous system may contribute to the treatment of trigeminal neuralgia Reply

Cerebrospinal fluid biomarkers of inflammation in trigeminal neuralgia patients operated with microvascular decompression

Ericson, Hans; Abu Hamdeh, Sami; Freyhult, Eva; Stiger, Fredrik et al.

Part of Pain, p. 2603-2611, 2019

DOI for Cerebrospinal fluid biomarkers of inflammation in trigeminal neuralgia patients operated with microvascular decompression

Ultrasensitive Immunoprofiling of Plasma Extracellular Vesicles Identifies Syndecan-1 as a Potential Tool for Minimally Invasive Diagnosis of Glioma

Chandran, Vineesh Indira; Welinder, Charlotte; Mansson, Ann-Sofie; Offer, Svenja et al.

Part of Clinical Cancer Research, p. 3115-3127, 2019

DOI for Ultrasensitive Immunoprofiling of Plasma Extracellular Vesicles Identifies Syndecan-1 as a Potential Tool for Minimally Invasive Diagnosis of Glioma

Skalkidou, Alkistis; Sundström Poromaa, Inger; Iliadis, Stavros I.; Huizink, Anja C. et al.

Part of Psychoneuroendocrinology, p. 296-305, 2019

DOI for Stress-related genetic polymorphisms in association with peripartum depression symptoms and stress hormones: A longitudinal population-based study

Reduction in White Blood Cell, Neutrophil and Red Blood Cell counts Related to Gender, HLA and Islet Autoantibodies in Swedish TEDDY Children at Increased Risk for Type 1 Diabetes

Salami, Falastin; Lee, Hye-Seung; Freyhult, Eva; Larsson, Helena Elding et al.

Part of Diabetes, 2018

DOI for Reduction in White Blood Cell, Neutrophil and Red Blood Cell counts Related to Gender, HLA and Islet Autoantibodies in Swedish TEDDY Children at Increased Risk for Type 1 Diabetes

Plasma Protein Profiling Reveal Osteoprotegerin as a Marker of Prognostic Impact for Colorectal Cancer

Birgisson, H; Tsimogiannis, Kostas; Freyhult, Eva; Kamali-Moghaddam, Masood

Part of Translational Oncology, p. 1034-1043, 2018

Lower inflammatory markers in women with antenatal depression brings the M1/M2 balance into focus from a new direction

Edvinsson, Åsa; Bränn, Emma; Hellgren, Charlotte; Freyhult, Eva et al.

Part of Psychoneuroendocrinology, p. 15-25, 2017

DOI for Lower inflammatory markers in women with antenatal depression brings the M1/M2 balance into focus from a new direction

Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assays.

Larssen, Pia; Wik, Lotta; Czarnewski, Paulo; Eldh, Maria et al.

Part of Molecular & Cellular Proteomics, 2017

DOI for Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assays.

Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assay

Larssen, Pia; Wik, Lotta; Czarnewski, Paulo; Eldh, Maria et al.

Part of Molecular & Cellular Proteomics, p. 502-511, 2017

DOI for Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assay

Antibody Affinity Against 2009 A/H1N1 Influenza and Pandemrix Vaccine Nucleoproteins Differs Between Childhood Narcolepsy Patients and Controls

Lind, Alexander; Freyhult, Eva; Ramelius, Anita; Olsson, Tomas et al.

Part of Viral immunology, p. 590-600, 2017

DOI for Antibody Affinity Against 2009 A/H1N1 Influenza and Pandemrix Vaccine Nucleoproteins Differs Between Childhood Narcolepsy Patients and Controls

Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes

Lindqvist, C. Mårten; Lundmark, Anders; Nordlund, Jessica; Freyhult, Eva et al.

Part of Oncotarget, p. 64071-64088, 2016

DOI for Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes

Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1

Landegren, Nils; Sharon, Donald; Freyhult, Eva; Hallgren, Åsa et al.

Part of Scientific Reports, 2016

A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients

Lind, Anne-Li; Yu, Di; Freyhult, Eva; Bodolea, Constantin et al.

Part of PLOS ONE, 2016

A Machine Learning Approach to Explain Drug Selectivity to Soluble and Membrane Protein Targets

Freyhult, Eva; Gustafsson, Mats G.; Strömbergsson, Helena

Part of Molecular Informatics, p. 44-52, 2015

DOI for A Machine Learning Approach to Explain Drug Selectivity to Soluble and Membrane Protein Targets

Transglutaminase 4 as a prostate autoantigen in male subfertility

Landegren, Nils; Sharon, Donald; Shum, Anthony K.; Khan, Imran S. et al.

Part of Science Translational Medicine, 2015

DOI for Transglutaminase 4 as a prostate autoantigen in male subfertility

FGF2 as a potential prognostic biomarker for proneural glioma patients

Sooman, Linda; Freyhult, Eva; Jaiswal, Archita; Navani, Sanjay et al.

Part of Acta Oncologica, p. 385-394, 2015

DOI for FGF2 as a potential prognostic biomarker for proneural glioma patients

HLA class I is most tightly linked to levels of tapasin compared with other antigen-processing proteins in glioblastoma

Thuring, Camilla; Follin, Elna; Geironson, Linda; Freyhult, Eva et al.

Part of British Journal of Cancer, p. 952-962, 2015

DOI for HLA class I is most tightly linked to levels of tapasin compared with other antigen-processing proteins in glioblastoma

Identifying Food Consumption Patterns among Young Consumers by Unsupervised and Supervised Multivariate Data Analysis

Hammerling, Ulf; Freyhult, Eva; Edberg, Anna; Sand, Salomon et al.

Part of European Journal of Nutrition & Food Safety, p. 392-403, 2014

DOI for Identifying Food Consumption Patterns among Young Consumers by Unsupervised and Supervised Multivariate Data Analysis

OnPLS integration of transcriptomic, proteomic and metabolomic data shows multi-level oxidative stress responses in the cambium of transgenic hipI- superoxide dismutase Populus plants

Srivastava, Vaibhav; Obudulu, Ogonna; Bygdell, Joakim; Löfstedt, Tommy et al.

Part of BMC Genomics, p. 893, 2013

DOI for OnPLS integration of transcriptomic, proteomic and metabolomic data shows multi-level oxidative stress responses in the cambium of transgenic hipI- superoxide dismutase Populus plants

Classification of microarrays: synergistic effects between normalization, gene selection and machine learning

Önskog, Jenny; Freyhult, Eva; Landfors, Mattias; Ryden, Patrik et al.

Part of BMC Bioinformatics, p. 390, 2011

Fisher: a program for the detection of H/ACA snoRNAs using MFE secondary structure prediction and comparative genomics -- assessment and update.

Freyhult, Eva; Edvardsson, Sverker Edvardsson; Tamas, Ivica Tamas; Moulton, Vincent et al.

Part of BMC Research Notes 2008, 2008

Evolution of genes and genomes on the Drosophila phylogeny

Clark, Andrew G.; Eisen, Michael B.; Smith, Douglas R.; Bergman, Casey M. et al.

Part of Nature, p. 203-218, 2007

DOI for Evolution of genes and genomes on the Drosophila phylogeny

Boltzmann probability of RNA structural neighbors and riboswitch detection

Freyhult, Eva; Moulton, Vincent; Clote, Peter

Part of Bioinformatics, p. 2054-2062, 2007

DOI for Boltzmann probability of RNA structural neighbors and riboswitch detection

RNAbor: a web server for RNA structural neighbors

Freyhult, Eva; Moulton, Vincent; Clote, Peter

Part of Nucleic Acids Research, 2007

DOI for RNAbor: a web server for RNA structural neighbors

Exploring genomic dark matter: A critical assessment of the performance of homology search methods on noncoding RNA

Freyhult, Eva; Bollback, Jonathan P.; Gardner, Paul P.

Part of Genome Research, p. 117-125, 2007

DOI for Exploring genomic dark matter: A critical assessment of the performance of homology search methods on noncoding RNA

New computational methods reveal tRNA identity element divergence between Proteobacteria and Cyanobacteria

Freyhult, Eva; Cui, Yuanyuan; Nilsson, Olle; Ardell, David H.

Part of Biochimie, p. 1276-1288, 2007

DOI for New computational methods reveal tRNA identity element divergence between Proteobacteria and Cyanobacteria

Visualizing bacterial tRNA identity determinants and antideterminants using function logos and inverse function logos.

Freyhult, Eva; Moulton, Vincent; Ardell, David

Part of Nucleic Acids Research, p. 905-916, 2006

A comparison of RNA folding measures.

Freyhult, Eva; Gardner, Paul P; Moulton, Vincent

Part of BMC Bioinformatics, p. 241, 2005

Unbiased descriptor and parameter selection confirms the potential of proteochemometric modelling

Freyhult, Eva; Prusis, Peteris; Lapinsh, Maris; Wikberg, Jarl E S et al.

Part of BMC Bioinformatics, p. 50, 2005

DOI for Unbiased descriptor and parameter selection confirms the potential of proteochemometric modelling

Predicting RNA structure using mutual information.

Freyhult, Eva; Moulton, Vincent; Gardner, Paul

Part of Applied Bioinformatics, p. 53-59, 2005

Structural modeling extends QSAR analysis of antibody-lysozyme interactions to 3D-QSAR

Freyhult, E; Andersson, K; Gustafsson, M G

Part of Biophysical Journal, p. 2264-2272, 2003

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