Marika Nestor

Targeting mutant p53: Evaluation of novel anti-p53^R175H monoclonal antibodies as diagnostic tools

Spiegelberg, Diana; Hwang, Le-Ann; Pua, Khian Hong; Kumar, Sashwini Chandra et al.

Part of Scientific Reports, 2025

• DOI for Targeting mutant p53: Evaluation of novel anti-p53^R175H monoclonal antibodies as diagnostic tools
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MDM2/MDMX inhibition by Sulanemadlin synergizes with anti-Programmed Death 1 immunotherapy in wild-type p53 tumors

Ingelshed, Katrine; Melssen, Marit M.; Kannan, Pavitra; Chandramohan, Arun et al.

Part of iScience, 2024

• DOI for MDM2/MDMX inhibition by Sulanemadlin synergizes with anti-Programmed Death 1 immunotherapy in wild-type p53 tumors
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Design-Rules for Stapled Alpha-Helical Peptides with On-Target In Vivo Activity: Application to Mdm2/X dual antagonists

Chandramohan, Arun; Josien, Hubert; Yuen, Tsz Ying; Duggal, Ruchia et al.

Part of Nature Communications, 2024

• DOI for Design-Rules for Stapled Alpha-Helical Peptides with On-Target In Vivo Activity: Application to Mdm2/X dual antagonists
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Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists

Chandramohan, Arun; Josien, Hubert; Yuen, Tsz Ying; Duggal, Ruchia et al.

Part of Nature Communications, 2024

• DOI for Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists
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Selection, characterization and in vivo evaluation of novel CD44v6-targeting antibodies for targeted molecular radiotherapy

Mortensen, Anja; Berglund, Hanna; Segerström, Lova; Walle, M. et al.

Part of Scientific Reports, 2023

• DOI for Selection, characterization and in vivo evaluation of novel CD44v6-targeting antibodies for targeted molecular radiotherapy
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Targeting mutant p53: Evaluation of novel anti-p53^R175H monoclonal antibodies as diagnostic tools

Spiegelberg, Diana; Hwang, Le-Ann; Pua, Khian Hong; Kumar, Sashwini Chandra et al.

Part of Scientific Reports, 2025

• DOI for Targeting mutant p53: Evaluation of novel anti-p53^R175H monoclonal antibodies as diagnostic tools
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MDM2/MDMX inhibition by Sulanemadlin synergizes with anti-Programmed Death 1 immunotherapy in wild-type p53 tumors

Ingelshed, Katrine; Melssen, Marit M.; Kannan, Pavitra; Chandramohan, Arun et al.

Part of iScience, 2024

• DOI for MDM2/MDMX inhibition by Sulanemadlin synergizes with anti-Programmed Death 1 immunotherapy in wild-type p53 tumors
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Design-Rules for Stapled Alpha-Helical Peptides with On-Target In Vivo Activity: Application to Mdm2/X dual antagonists

Chandramohan, Arun; Josien, Hubert; Yuen, Tsz Ying; Duggal, Ruchia et al.

Part of Nature Communications, 2024

• DOI for Design-Rules for Stapled Alpha-Helical Peptides with On-Target In Vivo Activity: Application to Mdm2/X dual antagonists
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Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists

Chandramohan, Arun; Josien, Hubert; Yuen, Tsz Ying; Duggal, Ruchia et al.

Part of Nature Communications, 2024

• DOI for Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists
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Selection, characterization and in vivo evaluation of novel CD44v6-targeting antibodies for targeted molecular radiotherapy

Mortensen, Anja; Berglund, Hanna; Segerström, Lova; Walle, M. et al.

Part of Scientific Reports, 2023

• DOI for Selection, characterization and in vivo evaluation of novel CD44v6-targeting antibodies for targeted molecular radiotherapy
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p53 stabilisation potentiates [¹⁷⁷Lu]Lu-DOTATATE treatment in neuroblastoma xenografts

Berglund, Hanna; Lundsten Salomonsson, Sara; Mohajershojai, Tabassom; Ferrer Gago, Fernando Jose et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2023

• DOI for p53 stabilisation potentiates [¹⁷⁷Lu]Lu-DOTATATE treatment in neuroblastoma xenografts
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Enhanced Therapeutic Effects of ¹⁷⁷Lu-DOTA-M5A in Combination with Heat Shock Protein 90 Inhibitor Onalespib in Colorectal Cancer Xenografts

Mohajershojai, Tabassom; Spangler, Douglas; Chopra, Saloni; Frejd, Fredrik Y. et al.

Part of Cancers, 2023

• DOI for Enhanced Therapeutic Effects of ¹⁷⁷Lu-DOTA-M5A in Combination with Heat Shock Protein 90 Inhibitor Onalespib in Colorectal Cancer Xenografts
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Utilizing CD44v6 and V600EBRAF-mutation for in vitro targeted combination therapy of thyroid carcinomas

Mortensen, Anja; Imgenberg-Kreuz, Juliana; Spiegelberg, Diana; Botling, J. et al.

Part of Heliyon, 2023

• DOI for Utilizing CD44v6 and V600EBRAF-mutation for in vitro targeted combination therapy of thyroid carcinomas
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Complementarity-determining region clustering may cause CAR-T cell dysfunction

Sarén, Tina; Saronio, Giulia; Marti Torrell, Paula; Zhu, Xu et al.

Part of Nature Communications, 2023

• DOI for Complementarity-determining region clustering may cause CAR-T cell dysfunction
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Photoactive immunoconjugates for targeted photodynamic therapy of cancer

Fernandes, Sara R.G.; Mohajershojai, Tabassom; Lundsten, Sara; Sarmento, Bruno et al.

Part of Journal of Photochemistry and Photobiology. B, 2023

• DOI for Photoactive immunoconjugates for targeted photodynamic therapy of cancer

In Vitro Characterization of Lu-177-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer

Mohajershojai, Tabassom; Jha, Preeti; Bostroem, Anna; Frejd, Fredrik Y. et al.

Part of Frontiers in Oncology, 2022

• DOI for In Vitro Characterization of Lu-177-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer
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Conformation specific antagonistic high affinity antibodies to the RON receptor kinase for imaging and therapy

Yu Koh, Xin; Koh, Xiao Hui; Spiegelberg, Diana; Jha, Preeti et al.

Part of Scientific Reports, 2022

• DOI for Conformation specific antagonistic high affinity antibodies to the RON receptor kinase for imaging and therapy
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The MDM2 Inhibitor Navtemadlin Arrests Mouse Melanoma Growth In Vivo and Potentiates Radiotherapy

Ingelshed, Katrine; Spiegelberg, Diana; Kannan, Pavitra; Påvénius, Linnéa et al.

Part of Cancer Research Communications, p. 1075-1088, 2022

• DOI for The MDM2 Inhibitor Navtemadlin Arrests Mouse Melanoma Growth In Vivo and Potentiates Radiotherapy
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p53-Mediated Radiosensitization of ¹⁷⁷Lu-DOTATATE in Neuroblastoma Tumor Spheroids

Lundsten, Sara; Berglund, Hanna; Jha, Preeti; Krona, Cecilia et al.

Part of Biomolecules, 2021

• DOI for p53-Mediated Radiosensitization of ¹⁷⁷Lu-DOTATATE in Neuroblastoma Tumor Spheroids
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Improved sensitivity in hydrophilic interaction liquid chromatography-electrospray-mass spectrometry after removal of sodium and potassium ions from biological samples

Erngren, Ida; Nestor, Marika; Pettersson, Curt; Hedeland, Mikael

Part of Metabolites, 2021

• DOI for Improved sensitivity in hydrophilic interaction liquid chromatography-electrospray-mass spectrometry after removal of sodium and potassium ions from biological samples
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Polymeric micelles targeted against CD44v6 receptor increase niclosamide efficacy against colorectal cancer stem cells and reduce circulating tumor cells in vivo

Andrade, Fernanda; Rafael, Diana; Vilar-Hernandez, Mireia; Montero, Sara et al.

Part of Journal of Controlled Release, p. 198-212, 2021

• DOI for Polymeric micelles targeted against CD44v6 receptor increase niclosamide efficacy against colorectal cancer stem cells and reduce circulating tumor cells in vivo

The Novel Anti-cMet Antibody seeMet 12 Potentiates Sorafenib Therapy and Radiotherapy in a Colorectal Cancer Model

Spiegelberg, Diana; Lundgren Mortensen, Anja Charlotte; Palupi, Kartika Dyah; Micke, Patrick et al.

Part of Frontiers in Oncology, 2020

• DOI for The Novel Anti-cMet Antibody seeMet 12 Potentiates Sorafenib Therapy and Radiotherapy in a Colorectal Cancer Model
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A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma

Johansson, Patrik; Krona, Cecilia; Kundu, Soumi; Doroszko, Milena et al.

Part of Cell Reports, 2020

• DOI for A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma
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The HSP90 inhibitor Onalespib exerts synergistic anti-cancer effects when combined with radiotherapy: an in vitro and in vivo approach

Spiegelberg, Diana; Abramenkovs, Andris; Mortensen, Anja; Lundsten, Sara et al.

Part of Scientific Reports, 2020

• DOI for The HSP90 inhibitor Onalespib exerts synergistic anti-cancer effects when combined with radiotherapy: an in vitro and in vivo approach
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Enhancing the therapeutic effects of in vitro targeted radionuclide therapy of 3D multicellular tumor spheroids using the novel stapled MDM2/X-p53 antagonist PM2

Mortensen, Anja; Morin, Eric; Brown, Christopher J.; Lane, David P. et al.

Part of EJNMMI Research, 2020

• DOI for Enhancing the therapeutic effects of in vitro targeted radionuclide therapy of 3D multicellular tumor spheroids using the novel stapled MDM2/X-p53 antagonist PM2
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The radiosensitizer Onalespib increases complete remission in Lu-177-DOTATATE-treated mice bearing neuroendocrine tumor xenografts

Lundsten, Sara; Spiegelberg, Diana; Raval, Nakul; Nestor, Marika

Part of European Journal of Nuclear Medicine and Molecular Imaging, p. 980-990, 2020

• DOI for The radiosensitizer Onalespib increases complete remission in Lu-177-DOTATATE-treated mice bearing neuroendocrine tumor xenografts
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Tumor-Targeted Delivery of the p53-Activating Peptide VIP116 with PEG-Stabilized Lipodisks

Lundsten, Sara; Hernandez, Victor Agmo; Gedda, Lars; Sarén, Tina et al.

Part of Nanomaterials, 2020

• DOI for Tumor-Targeted Delivery of the p53-Activating Peptide VIP116 with PEG-Stabilized Lipodisks
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Bivalent binding on cells varies between anti-CD20 antibodies and is dose-dependent

Bondza, Sina; ten Broeke, Toine; Nestor, Marika; Leusen, Jeanette H. W. et al.

Part of mAbs, 2020

• DOI for Bivalent binding on cells varies between anti-CD20 antibodies and is dose-dependent

The Stapled Peptide PM2 Stabilizes p53 Levels and Radiosensitizes Wild-Type p53 Cancer Cells

Lundgren Mortensen, Anja; Spiegelberg, Diana; Brown, Christopher John; Lane, David Philip et al.

Part of Frontiers in Oncology, 2019

• DOI for The Stapled Peptide PM2 Stabilizes p53 Levels and Radiosensitizes Wild-Type p53 Cancer Cells
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Exploring Radiation Response in Two Head and Neck Squamous Carcinoma Cell Lines Through Metabolic Profiling

Lindell Jonsson, Eva; Erngren, Ida; Engskog, Mikael; Haglöf, Jakob et al.

Part of Frontiers in Oncology, 2019

• DOI for Exploring Radiation Response in Two Head and Neck Squamous Carcinoma Cell Lines Through Metabolic Profiling
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The HSP90 inhibitor onalespib potentiates Lu-177-DOTATATE therapy in neuroendocrine tumor cells

Lundsten, Sara; Spiegelberg, Diana; Stenerlöw, Bo; Nestor, Marika

Part of International Journal of Oncology, p. 1287-1295, 2019

• DOI for The HSP90 inhibitor onalespib potentiates Lu-177-DOTATATE therapy in neuroendocrine tumor cells
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Adduct formation in electrospray ionisation-mass spectrometry with hydrophilic interaction liquid chromatography is strongly affected by the inorganic ion concentration of the samples

Erngren, Ida; Haglöf, Jakob; Engskog, Mikael K R; Nestor, Marika et al.

Part of Journal of Chromatography A, p. 174-182, 2019

• DOI for Adduct formation in electrospray ionisation-mass spectrometry with hydrophilic interaction liquid chromatography is strongly affected by the inorganic ion concentration of the samples

Preclinical evaluation of a novel engineered recombinant human anti-CD44v6 antibody for potential use in radio-immunotherapy

Mortensen, Anja; Spiegelberg, Diana; Haylock, Anna-Karin; Lundqvist, Hans et al.

Part of International Journal of Oncology, p. 1875-1885, 2018

• DOI for Preclinical evaluation of a novel engineered recombinant human anti-CD44v6 antibody for potential use in radio-immunotherapy
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First in vivo study of the MDM2/MDMX-p53 antagonist PM2 as potentiator of external radiotherapy in wt p53 cancer

Spiegelberg, Diana; Mortensen, Anja C.; Lundsten, Sara; Brown, C. J. et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2018

• DOI for First in vivo study of the MDM2/MDMX-p53 antagonist PM2 as potentiator of external radiotherapy in wt p53 cancer

Potentiating Lu-177-DOTATATE Therapy By HSP90 Inhibition - First In Vivo Study

Lundsten, Sara; Spiegelberg, Diana; Raval, Nakul; Stenerlöw, Bo et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2018

Fab-conjugated PLGA nanoparticles effectively target cancer cells expressing human CD44v6

Kennedy, Patrick J.; Sousa, Flavia; Ferreira, Daniel; Pereira, Carla et al.

Part of Acta Biomaterialia, p. 208-218, 2018

• DOI for Fab-conjugated PLGA nanoparticles effectively target cancer cells expressing human CD44v6

The MDM2/MDMX-p53 Antagonist PM2 Radiosensitizes Wild-Type p53 Tumors

Spiegelberg, Diana; Mortensen, Anja; Lundsten, Sara; Brown, Christopher J. et al.

Part of Cancer Research, p. 5084-5093, 2018

• DOI for The MDM2/MDMX-p53 Antagonist PM2 Radiosensitizes Wild-Type p53 Tumors

Method selectivity evaluation using the co-feature ratio in LC/MS metabolomics: Comparison of HILIC stationary phase performance for the analysis of plasma, urine and cell extracts.

Elmsjö, Albert; Haglöf, Jakob; Engskog, Mikael K R; Erngren, Ida et al.

Part of Journal of Chromatography A, p. 49-56, 2018

• DOI for Method selectivity evaluation using the co-feature ratio in LC/MS metabolomics: Comparison of HILIC stationary phase performance for the analysis of plasma, urine and cell extracts.

Impact of surfactants on the target recognition of Fab-conjugated PLGA nanoparticles

Kennedy, Patrick J.; Perreira, Ines; Ferreira, Daniel; Nestor, Marika et al.

Part of European journal of pharmaceutics and biopharmaceutics, p. 366-370, 2018

• DOI for Impact of surfactants on the target recognition of Fab-conjugated PLGA nanoparticles

Analysis of radiation effects in two irradiated tumor spheroid models

Al-Ramadan, Afkar; Mortensen, Anja; Carlsson, Jörgen; Nestor, Marika V.

Part of Oncology Letters, p. 3008-3016, 2018

• DOI for Analysis of radiation effects in two irradiated tumor spheroid models

Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells

Häggblad Sahlberg, Sara; Mortensen, Anja C.; Haglöf, Jakob; Engskog, Mikael K. R. et al.

Part of International Journal of Oncology, p. 5-14, 2017

• DOI for Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells
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Generation and evaluation of antibody agents for molecular imaging of CD44v6-expressing cancers

Haylock, Anna-Karin; Nilvebrant, Johan; Mortensen, Anja; Velikyan, Irina et al.

Part of Oncotarget, p. 65152-65170, 2017

• DOI for Generation and evaluation of antibody agents for molecular imaging of CD44v6-expressing cancers
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Radioiodination Of Small Stapled Peptides For p53 Therapy

Lundsten, Sara; Spiegelberg, Diana; Agmo Hernández, Víctor; Brown, C. et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2017

Novel Real-Time Proximity Assay for Characterizing Multiple Receptor Interactions on Living Cells

Bondza, Sina; Björkelund, Hanna; Nestor, Marika; Andersson, Karl et al.

Part of Analytical Chemistry, p. 13212-13218, 2017

• DOI for Novel Real-Time Proximity Assay for Characterizing Multiple Receptor Interactions on Living Cells

The HSP90-inhibitor Onalespib Potentiates Lu-177-Dotatate Treatment of Neuroendocrine Tumors

Lundsten, Sara; Mortensen, Anja; Makiniemi, A.; Spiegelberg, Diana et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2017

The Novel, Stapled HDM2/HDMX-p53 Antagonist PM2 Has Potent Antitumorigenic Activities and Enhances the Effects of External Radiotherapy

Mortensen, Anja C.; Spiegelberg, Diana; Brown, C.; Lane, D. P. et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2017

In Vivo Assessment of p53 Therapy as a Way of Enhancing Therapeutic Effects of Radiation

Mortensen, Anja C.; Spiegelberg, Diana; Lundsten, Sara; Brown, C. et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2017

In Vitro and In Vivo Growth Inhibitory and Radiosensitizing Effects of the Anti-HSP90 agent Onalespib

Spiegelberg, Diana; Lundsten, Sara; Mortensen, Anja C.; Abramenkovs, Andris et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2017

The co-feature ratio, a novel method for the measurement of chromatographic and signal selectivity in LC-MS-based metabolomics.

Elmsjö, Albert; Haglöf, Jakob; Engskog, Mikael K. R.; Nestor, Marika et al.

Part of Analytica Chimica Acta, p. 40-47, 2017

• DOI for The co-feature ratio, a novel method for the measurement of chromatographic and signal selectivity in LC-MS-based metabolomics.

Evaluation of a novel type of imaging probe based on a recombinant bivalent mini-antibody construct for detection of CD44v6-expressing squamous cell carcinoma

Haylock, Anna-Karin; Spiegelberg, Diana; Mortensen, Anja C.; Selvaraju, Ram K. et al.

Part of International journal of oncology, p. 461-470, 2016

• DOI for Evaluation of a novel type of imaging probe based on a recombinant bivalent mini-antibody construct for detection of CD44v6-expressing squamous cell carcinoma
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A real-time in vitro assay as a potential predictor of in vivo tumor imaging properties

Spiegelberg, Diana; Stenberg, Jonas; Haylock, Anna-Karin; Nestor, Marika

Part of Nuclear Medicine and Biology, p. 12-18, 2016

• DOI for A real-time in vitro assay as a potential predictor of in vivo tumor imaging properties

Molecular imaging of EGFR and CD44v6 for prediction and response monitoring of HSP90 inhibition in an in vivo squamous cell carcinoma model.

Spiegelberg, Diana; Mortensen, Anja C; Selvaraju, Ram K; Eriksson, Olof et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, p. 974-982, 2016

• DOI for Molecular imaging of EGFR and CD44v6 for prediction and response monitoring of HSP90 inhibition in an in vivo squamous cell carcinoma model.
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The novel HSP90 inhibitor AT13387 potentiates radiation effects in squamous cell carcinoma and adenocarcinoma cells

Spiegelberg, Diana; Dascalu, Adrian; Mortensen, Anja; Abramenkovs, Andris et al.

Part of Oncotarget, p. 35652-35666, 2015

• DOI for The novel HSP90 inhibitor AT13387 potentiates radiation effects in squamous cell carcinoma and adenocarcinoma cells
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Enhancing the effect of radiotherapy in cultured tumour cells using p53 therapy

Mortensen, Anja C.; Spiegelberg, Diana; Scott, A. M.; Lane, D. P. et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2015

A real-time in vitro assay as a potential predictor of in vivo tumour imaging properties

Spiegelberg, Diana; Stenberg, J.; Haylock, Anna-Karin; Nestor, Marika

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2015

Improving EGFR imaging by use of an anti-EGFRvIII monoclonal antibody: characterizations in an in vivo squamous cell carcinoma model

Spiegelberg, Diana; Mortensen, Anja C.; Selvaraju, Ram Kumar; Stenberg, J. et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2015

Molecular imaging of EGFR and EGFRvIII for prediction and response monitoring of HSP90 inhibition in an in vivo squamous cell carcinoma model

Spiegelberg, Diana; Mortensen, Anja C.; Selvaraju, Ram Kumar; Eriksson, Olof et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2015

In vivo characterization of the novel CD44v6-targeting Fab fragment AbD15179 for molecular imaging of squamous cell carcinoma: a dual-isotope study

Haylock, Anna-Karin; Spiegelberg, Diana; Nilvebrant, Johan; Sandström, Karl et al.

Part of EJNMMI Research, 2014

• DOI for In vivo characterization of the novel CD44v6-targeting Fab fragment AbD15179 for molecular imaging of squamous cell carcinoma: a dual-isotope study
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Impact of Conjugation of Antibodies and Antibody Fragments on Their Interaction With Target Antigens on Living Cells

Stenberg, Jonas; Bondza, Sina; Spiegelberg, Diana; Björkelund, Hanna et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2014

Evaluation of cancer stem cell markers CD133, CD44, CD24: association with AKT isoforms and radiation resistance in colon cancer cells.

Häggblad Sahlberg, Sara; Spiegelberg, Diana; Glimelius, Bengt; Stenerlöw, Bo et al.

Part of PLOS ONE, 2014

• DOI for Evaluation of cancer stem cell markers CD133, CD44, CD24: association with AKT isoforms and radiation resistance in colon cancer cells.
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Characterization of CD44 variant expression in head and neck squamous cell carcinomas

Spiegelberg, Diana; Kuku, Gamze; Selvaraju, Ram; Nestor, Marika

Part of Tumor Biology, p. 2053-2062, 2014

• DOI for Characterization of CD44 variant expression in head and neck squamous cell carcinomas
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Choice of labeling and cell line influences interactions between the Fab fragment AbD15179 and its target antigen CD44v6

Stenberg, Jonas; Spiegelberg, Diana; Karlsson, Hampus; Nestor, Marika

Part of Nuclear Medicine and Biology, p. 140-147, 2014

• DOI for Choice of labeling and cell line influences interactions between the Fab fragment AbD15179 and its target antigen CD44v6

Conjugation Effects on Antibody-Drug Conjugates: Evaluation of Interaction Kinetics in Real Time on Living Cells

Bondza, Sina; Stenberg, Jonas; Nestor, Marika; Andersson, Karl et al.

Part of Molecular Pharmaceutics, p. 4154-4163, 2014

• DOI for Conjugation Effects on Antibody-Drug Conjugates: Evaluation of Interaction Kinetics in Real Time on Living Cells

In vivo characterization of a novel engineered CD44v6-targeting bivalent antibody fragment AbD19384 for molecular imaging of squamous cell carcinoma

Mortensen, Anja C.; Spegelberg, Diana; Haylock, Anna-Karin; Selvaraju, Ram Kumar et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2014

Evaluation of biomarkers for imaging and radio-immunotherapy in combination with HSP90 inhibition in squamous cell carcinomas

Spiegelberg, Diana; Mortensen, Anja C.; Haylock, Anna-Karin; Selvaraju, Ram Kumar et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2014

In vivo characterization of CD44v6-targeting Fab fragments for molecular imaging of squamous cell carcinoma: a dual isotope study

Spiegelberg, Diana; Haylock, Anna-Karin; Nestor, Marika

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2013

A novel CD44v6 targeting antibody fragment with improved tumor-to-blood ratio

Sandström, Karl; Haylock, Anna-Karin; Spiegelberg, Diana; Qvarnström, Fredrik et al.

Part of International Journal of Oncology, p. 1525-1532, 2012

• DOI for A novel CD44v6 targeting antibody fragment with improved tumor-to-blood ratio

Selection and characterisation of human CD44v6-binding antibody fragments for specific targeting of head and neck squamous cell carcinoma

Nilvebrant, J.; Kuku, G.; Björkelund, Hanna; Nestor, Marika

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2012

Selection and in vitro characterization of human CD44v6-binding antibody fragments

Nilvebrant, Johan; Kuku, Gamze; Björkelund, Hanna; Nestor, Marika

Part of Biotechnology and applied biochemistry, p. 367-380, 2012

• DOI for Selection and in vitro characterization of human CD44v6-binding antibody fragments

Targeted therapy in head and neck cancer

Kundu, S K; Nestor, Marika

Part of Tumor Biology, p. 707-721, 2012

• DOI for Targeted therapy in head and neck cancer

Characterization of CD44 Variant Expression in Cultured Head & Neck Squamous Cell Carcinomas for Possible Use in Radio-Immunotargeting

Spiegelberg, Diana; Nestor, Marika

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2012

Improved Tumor-to-Organ Ratios of a Novel ⁶⁷Ga-Human Epidermal Growth Factor Radionuclide Conjugate with Preadministered Antiepidermal Growth Factor Receptor Affibody Molecules

Sandström, Karl; Haylock, Anna-Karin; Velikyan, Irina; Spiegelberg, Diana et al.

Part of Cancer Biotherapy and Radiopharmaceuticals, p. 593-601, 2011

• DOI for Improved Tumor-to-Organ Ratios of a Novel ⁶⁷Ga-Human Epidermal Growth Factor Radionuclide Conjugate with Preadministered Antiepidermal Growth Factor Receptor Affibody Molecules

Effect of cetuximab in combination with alpha-radioimmunotherapy in cultured squamous cell carcinomas

Nestor, Marika; Sundström, Magnus; Anniko, Matti; Tolmachev, Vladimir

Part of Nuclear Medicine and Biology, p. 103-112, 2011

• DOI for Effect of cetuximab in combination with alpha-radioimmunotherapy in cultured squamous cell carcinomas

Blocking EGFR in the liver improves the tumor-to-liver uptake ratio of radiolabeled EGF

Kareem, Heewa; Sandström, Karl; Elia, Ronny; Gedda, Lars et al.

Part of Tumor Biology, p. 79-87, 2010

• DOI for Blocking EGFR in the liver improves the tumor-to-liver uptake ratio of radiolabeled EGF

Effect of cetuximab treatment in squamous cell carcinomas

Nestor, Marika

Part of Tumor Biology, p. 141-147, 2010

• DOI for Effect of cetuximab treatment in squamous cell carcinomas

The use of closo-dodecaborate-containing linker improves targeting of HNSCC xenografts with radioiodinated chimeric monoclonal antibody U36

Cheng, Junping; Engström, Mats; Ekberg, Tomas; Nestor, Marika et al.

Part of Molecular Medicine Reports, p. 155-160, 2010

• DOI for The use of closo-dodecaborate-containing linker improves targeting of HNSCC xenografts with radioiodinated chimeric monoclonal antibody U36

Targeting CD44v6 expressed in head and neck squamous cell carcinoma: preclinical characterization of an 111In-labeled monoclonal antibody

Sandström, Karl; Nestor, Marika; Ekberg, Tomas; Engström, Mats et al.

Part of Tumor Biology, p. 137-144, 2008

• DOI for Targeting CD44v6 expressed in head and neck squamous cell carcinoma: preclinical characterization of an 111In-labeled monoclonal antibody

Characterization of In-111 and Lu-177-labeled antibodies binding to CD44v6 using a novel automated radioimmunoassay

Nestor, Marika; Andersson, Karl; Lundqvist, Hans

Part of Journal of Molecular Recognition, p. 179-183, 2008

• DOI for Characterization of In-111 and Lu-177-labeled antibodies binding to CD44v6 using a novel automated radioimmunoassay

Quantification of CD44v6 and EGFR expression in head and neck squamous cell carcinomas using a single-dose radioimmunoassay

Nestor, Marika; Ekberg, Tomas; Dring, John; van Dongen, Guus et al.

Part of Tumor Biology, p. 253-263, 2007

• DOI for Quantification of CD44v6 and EGFR expression in head and neck squamous cell carcinomas using a single-dose radioimmunoassay

Immuno-PET of undifferentiated thyroid carcinoma with radioiodine-labelled antibody cMAb U36: application to antibody tumour uptake studies

Fortin, Marc-André; Salnikov, Alexei V.; Nestor, Marika; Heldin, Nils-Erik et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, p. 1376-1387, 2007

• DOI for Immuno-PET of undifferentiated thyroid carcinoma with radioiodine-labelled antibody cMAb U36: application to antibody tumour uptake studies

Radioimmunotherapy with astatine-211 using chimeric monoclonal antibody U36 in head and neck squamous cell carcinoma

Cheng, Junping; Ekberg, Tomas; Engström, Mats; Nestor, Marika et al.

Part of The Laryngoscope, p. 1013-1018, 2007

• DOI for Radioimmunotherapy with astatine-211 using chimeric monoclonal antibody U36 in head and neck squamous cell carcinoma

Expression of EGFR, HER2, HER3, and HER4 in metastatic squamous cell carcinomas of the oral cavity and base of tongue

Ekberg, Thomas; Nestor, Marika; Engström, Mats; Nordgren, Hans et al.

Part of International Journal of Oncology, p. 1177-85, 2005

In vitro evaluation of the astatinated chimeric monoclonal antibody U36, a potential candidate for treatment of head and neck squamous cell carcinoma

Nestor, Marika; Persson, Mikael; van Dongen, Guus A.; Jensen, Holger J. et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, p. 1296-304, 2005

• DOI for In vitro evaluation of the astatinated chimeric monoclonal antibody U36, a potential candidate for treatment of head and neck squamous cell carcinoma

Tumor-cell targeted EGF liposomes loaded with boronated acridine: Uptake and processing

Kullberg, Erika Bohl; Nestor, Marika; Gedda, Lars

Part of Pharmaceutical research, p. 229-236, 2003

• DOI for Tumor-cell targeted EGF liposomes loaded with boronated acridine: Uptake and processing

Biodistribution of the chimeric monoclonal antibody U36 radioiodinated with a closo-dodecaborate-containing linker: Comparison with other radioiodination methods

Nestor, Marika; Persson, Mikael; Cheng, Junping; Tolmachev, Vladimir et al.

Part of Bioconjugate chemistry, p. 805-10, 2003

• DOI for Biodistribution of the chimeric monoclonal antibody U36 radioiodinated with a closo-dodecaborate-containing linker: Comparison with other radioiodination methods

Targeted radionuclide therapy in head and neck cancer

Nestor, Marika V.

Part of Head and Neck, p. 666-678, 2010

• DOI for Targeted radionuclide therapy in head and neck cancer

Conjugated Therapy: Cancer of the Head and Neck

Nestor, Marika

Part of Targeted Radionuclide Therapy, Lippincott Williams & Wilkins, 2010

Selectivity evaluation using the co-feature ratio in LC/MS metabolomics: comparison of HILIC stationary phases’ performance for the analysis of plasma, urine and cell extracts.

Elmsjö, Albert; Haglöf, Jakob; Engskog, Mikael; Erngren, Ida et al.

Enhancing therapeutic effects of radio-immunotherapy using the novel stapled MDM2/X-p53 antagonist PM2

Mortensen, Anja C.; Morin, Eric; Brown, Christopher J; Claesson-Welsh, Lena et al.

Bivalent Binding on Cells varies between CD20 Antibodies and is Dose-dependent

Bondza, Sina; ten Broeke, Toine; Nestor, Marika; Leusen, Jeanette et al.

PD-1 blockade enhances therapeutic effects of ¹⁷⁷Lu-DOTA-M5A in colorectal cancer CEA-transgenic mice

Mohajershojai, Tabassom; Bengtsson, Emil; Vallin, Ingrid; Spangler, Douglas et al.

Therapeutic combination of HSP90 inhibition and radiation therapy reduces tumor growth in a syngeneic neuroblastoma mouse model.

Berglund, Hanna; Pereira, Beatriz; Nestor, Marika; Spiegelberg, Diana

Exploring real-time interaction analysis to monitor CD44 expression modulation in cancer cells by inhibiting Musashi-1 interactions with RNA

Pérez-Ropero, Guillermo; Ortstad, Nathalie; Nestor, Marika; Danielson, Helena et al.