Ibrahim Kaya
Researcher at Department of Pharmaceutical Biosciences; Research; Mass Spectrometry Imaging
- E-mail:
- ibrahim.kaya@uu.se
- Visiting address:
- Husargatan 3
- Postal address:
- Box 591
751 24 UPPSALA
Biography
Ibrahim was born in Eskişehir, Türkiye. He studied chemistry at the Izmir Institute of Technology (Türkiye) and the University of Chemistry and Technology, Prague (Czech Republic) and he graduated in 2013. He received his masters degree from the Izmir Institute of Technology (Türkiye) and the University of Gothenburg (Sweden) in 2015, working on laser plasma spectroscopy and MALDI mass spectrometry.
He received his PhD from the Sahlgrenska Academy, University of Gothenburg in 2020, working on the developments and applications of MALDI-ToF and ToF-SIMS mass spectrometry imaging methods for molecular neuroscience. Currently, he works at Uppsala University as a researcher in the group of Per Andrén developing MALDI-FT-ICR, MALDI-ToF and MALDI-TIMS-ToF mass spectrometry imaging methods for probing molecular pathology in Parkinson's Disease and L-DOPA-Induced Dyskinesia.

Publications
Selection of publications
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Advances in spatial mass spectrometry enable in-depth neuropharmacodynamics
Part of TIPS - Trends in Pharmacological Sciences, p. 740-753, 2022
- DOI for Advances in spatial mass spectrometry enable in-depth neuropharmacodynamics
- Download full text (pdf) of Advances in spatial mass spectrometry enable in-depth neuropharmacodynamics
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Part of The Analyst, p. 1169-1177, 2021
Recent publications
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Part of Translational Psychiatry, 2026
- DOI for Spatial lipidomic and neuron-specific transcriptomic signatures in the nucleus accumbens reveal phospholipid dyshomeostasis in depression-related maladaptations
- Download full text (pdf) of Spatial lipidomic and neuron-specific transcriptomic signatures in the nucleus accumbens reveal phospholipid dyshomeostasis in depression-related maladaptations
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Part of Neurobiology of Disease, 2026
- DOI for Spatial lipidomics identifies α-synuclein-induced lipid changes in an AAV-induced Parkinsonian mouse model
- Download full text (pdf) of Spatial lipidomics identifies α-synuclein-induced lipid changes in an AAV-induced Parkinsonian mouse model
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Part of npj Parkinson's Disease, 2025
- DOI for Brain-region-specific lipid dysregulation in L-DOPA-induced dyskinesia in a primate model of Parkinson's disease
- Download full text (pdf) of Brain-region-specific lipid dysregulation in L-DOPA-induced dyskinesia in a primate model of Parkinson's disease
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Part of Biochemistry, p. 2583-2595, 2025
- DOI for Cryo-Electron Microscopy Provides Mechanistic Insights into Solution-Dependent Polymorphism and Cross-Aggregation Phenomena of the Human and Rat Islet Amyloid Polypeptides
- Download full text (pdf) of Cryo-Electron Microscopy Provides Mechanistic Insights into Solution-Dependent Polymorphism and Cross-Aggregation Phenomena of the Human and Rat Islet Amyloid Polypeptides
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Part of Cell Death and Disease, 2025
- DOI for The CHCHD2-CHCHD10 protein complex is modulated by mitochondrial dysfunction and alters lipid homeostasis in the mouse brain
- Download full text (pdf) of The CHCHD2-CHCHD10 protein complex is modulated by mitochondrial dysfunction and alters lipid homeostasis in the mouse brain
All publications
Articles in journal
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Part of Translational Psychiatry, 2026
- DOI for Spatial lipidomic and neuron-specific transcriptomic signatures in the nucleus accumbens reveal phospholipid dyshomeostasis in depression-related maladaptations
- Download full text (pdf) of Spatial lipidomic and neuron-specific transcriptomic signatures in the nucleus accumbens reveal phospholipid dyshomeostasis in depression-related maladaptations
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Part of Neurobiology of Disease, 2026
- DOI for Spatial lipidomics identifies α-synuclein-induced lipid changes in an AAV-induced Parkinsonian mouse model
- Download full text (pdf) of Spatial lipidomics identifies α-synuclein-induced lipid changes in an AAV-induced Parkinsonian mouse model
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Part of npj Parkinson's Disease, 2025
- DOI for Brain-region-specific lipid dysregulation in L-DOPA-induced dyskinesia in a primate model of Parkinson's disease
- Download full text (pdf) of Brain-region-specific lipid dysregulation in L-DOPA-induced dyskinesia in a primate model of Parkinson's disease
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Part of Biochemistry, p. 2583-2595, 2025
- DOI for Cryo-Electron Microscopy Provides Mechanistic Insights into Solution-Dependent Polymorphism and Cross-Aggregation Phenomena of the Human and Rat Islet Amyloid Polypeptides
- Download full text (pdf) of Cryo-Electron Microscopy Provides Mechanistic Insights into Solution-Dependent Polymorphism and Cross-Aggregation Phenomena of the Human and Rat Islet Amyloid Polypeptides
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Part of Cell Death and Disease, 2025
- DOI for The CHCHD2-CHCHD10 protein complex is modulated by mitochondrial dysfunction and alters lipid homeostasis in the mouse brain
- Download full text (pdf) of The CHCHD2-CHCHD10 protein complex is modulated by mitochondrial dysfunction and alters lipid homeostasis in the mouse brain
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Part of Analytical Chemistry, p. 9033-9041, 2025
- DOI for Met-ID: An Open-Source Software for Comprehensive Annotation of Multiple On-Tissue Chemical Modifications in MALDI-MSI
- Download full text (pdf) of Met-ID: An Open-Source Software for Comprehensive Annotation of Multiple On-Tissue Chemical Modifications in MALDI-MSI
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Part of Analytical Chemistry, p. 1338-1346, 2025
- DOI for Comprehensive Approach for Sequential MALDI-MSI Analysis of Lipids, N-Glycans, and Peptides in Fresh-Frozen Rodent Brain Tissues
- Download full text (pdf) of Comprehensive Approach for Sequential MALDI-MSI Analysis of Lipids, N-Glycans, and Peptides in Fresh-Frozen Rodent Brain Tissues
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Hydrogen production by a fully de novo enzyme
Part of Dalton Transactions, p. 12905-12916, 2024
- DOI for Hydrogen production by a fully de novo enzyme
- Download full text (pdf) of Hydrogen production by a fully de novo enzyme
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Applying Spatial Metabolomics To Investigate Age- and Drug-Induced Neurochemical Changes
Part of ACS Chemical Neuroscience, p. 2822-2829, 2024
- DOI for Applying Spatial Metabolomics To Investigate Age- and Drug-Induced Neurochemical Changes
- Download full text (pdf) of Applying Spatial Metabolomics To Investigate Age- and Drug-Induced Neurochemical Changes
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Part of Chemical Communications, p. 9238-9241, 2024
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Part of npj Parkinson's Disease, 2023
- DOI for Spatial lipidomics reveals brain region-specific changes of sulfatides in an experimental MPTP Parkinson's disease primate model
- Download full text (pdf) of Spatial lipidomics reveals brain region-specific changes of sulfatides in an experimental MPTP Parkinson's disease primate model
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Part of Nature Communications, 2023
- DOI for Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents
- Download full text (pdf) of Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents
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Part of Journal of the American Society for Mass Spectrometry, p. 836-846, 2023
- DOI for On-Tissue Chemical Derivatization for Comprehensive Mapping of Brain Carboxyl and Aldehyde Metabolites by MALDI-MS Imaging
- Download full text (pdf) of On-Tissue Chemical Derivatization for Comprehensive Mapping of Brain Carboxyl and Aldehyde Metabolites by MALDI-MS Imaging
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Part of The Analyst, p. 1169-1177, 2021
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Part of Analytical and Bioanalytical Chemistry, p. 4181-4194, 2021
- DOI for (CO2)(n)(+), (H2O)(n)(+), and (H2O)(n)(+) (CO2) gas cluster ion beam secondary ion mass spectrometry: analysis of lipid extracts, cells, and Alzheimer's model mouse brain tissue
- Download full text (pdf) of (CO2)(n)(+), (H2O)(n)(+), and (H2O)(n)(+) (CO2) gas cluster ion beam secondary ion mass spectrometry: analysis of lipid extracts, cells, and Alzheimer's model mouse brain tissue
Articles, review/survey
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Advances in spatial mass spectrometry enable in-depth neuropharmacodynamics
Part of TIPS - Trends in Pharmacological Sciences, p. 740-753, 2022
- DOI for Advances in spatial mass spectrometry enable in-depth neuropharmacodynamics
- Download full text (pdf) of Advances in spatial mass spectrometry enable in-depth neuropharmacodynamics