Thierry Soussi

Low-penetrance TP53 variants are mainly hypomorphic: an underestimated issue with high clinical significance

Rodriguez, Lea; Leroy, Bernard; Toledo, Franck; Funk, Julianne Susanne et al.

Part of npj Genomic Medicine, 2026

• DOI for Low-penetrance TP53 variants are mainly hypomorphic: an underestimated issue with high clinical significance
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Misclassification of TP53 germline variants: implications for survival analysis in AML transplant studies

Rodriguez, Lea; Delhommeau, Francois; Soussi, Thierry

Part of Leukemia, p. 3054-3055, 2025

• DOI for Misclassification of TP53 germline variants: implications for survival analysis in AML transplant studies
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A novel PML germline variant as a candidate predisposing genetic aberration in familial acute myeloid leukaemia.

Soussi, Thierry; Kundu, Snehangshu; Gerbaud, Pauline; Pandzic, Tatjana et al.

Part of British Journal of Haematology, p. 1118-1121, 2025

• DOI for A novel PML germline variant as a candidate predisposing genetic aberration in familial acute myeloid leukaemia.
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The TP53 tumor suppressor gene: From molecular biology to clinical investigations

Baliakas, Panagiotis; Soussi, Thierry

Part of Journal of Internal Medicine, p. 78-96, 2025

• DOI for The TP53 tumor suppressor gene: From molecular biology to clinical investigations
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TP53 Mutations Detected by NGS Are a Major Clinical Risk Factor for Stratifying Mantle Cell Lymphoma

Lazarian, Grégory; Chemali, Lotfi; Bensalah, Merieme; Zindel, Carla et al.

Part of American Journal of Hematology, p. 933-936, 2025

• DOI for TP53 Mutations Detected by NGS Are a Major Clinical Risk Factor for Stratifying Mantle Cell Lymphoma

Low-penetrance TP53 variants are mainly hypomorphic: an underestimated issue with high clinical significance

Rodriguez, Lea; Leroy, Bernard; Toledo, Franck; Funk, Julianne Susanne et al.

Part of npj Genomic Medicine, 2026

• DOI for Low-penetrance TP53 variants are mainly hypomorphic: an underestimated issue with high clinical significance
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Misclassification of TP53 germline variants: implications for survival analysis in AML transplant studies

Rodriguez, Lea; Delhommeau, Francois; Soussi, Thierry

Part of Leukemia, p. 3054-3055, 2025

• DOI for Misclassification of TP53 germline variants: implications for survival analysis in AML transplant studies
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A novel PML germline variant as a candidate predisposing genetic aberration in familial acute myeloid leukaemia.

Soussi, Thierry; Kundu, Snehangshu; Gerbaud, Pauline; Pandzic, Tatjana et al.

Part of British Journal of Haematology, p. 1118-1121, 2025

• DOI for A novel PML germline variant as a candidate predisposing genetic aberration in familial acute myeloid leukaemia.
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TP53 Mutations Detected by NGS Are a Major Clinical Risk Factor for Stratifying Mantle Cell Lymphoma

Lazarian, Grégory; Chemali, Lotfi; Bensalah, Merieme; Zindel, Carla et al.

Part of American Journal of Hematology, p. 933-936, 2025

• DOI for TP53 Mutations Detected by NGS Are a Major Clinical Risk Factor for Stratifying Mantle Cell Lymphoma

Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations

Funk, Julianne S.; Klimovich, Maria; Drangenstein, Daniel; Pielhoop, Ole et al.

Part of Nature Genetics, p. 140-153, 2025

• DOI for Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations
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Cancer associated variant enrichment CAVE, a gene agnostic approach to identify low burden variants in chronic lymphocytic leukemia

Yaacov, Adar; Lazarian, Gregory; Pandzic, Tatjana; Weström, Simone et al.

Part of Scientific Reports, 2024

• DOI for Cancer associated variant enrichment CAVE, a gene agnostic approach to identify low burden variants in chronic lymphocytic leukemia
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The Broad Spectrum of TP53 Mutations in CLL: Evidence of Multiclonality and Novel Mutation Hotspots

Lazarian, Gregory; Leroy, Bernard; Theves, Floriane; Hormi, Myriam et al.

Part of Human Mutation, 2023

• DOI for The Broad Spectrum of TP53 Mutations in CLL: Evidence of Multiclonality and Novel Mutation Hotspots

Letter to the editor

Soussi, Thierry

Part of Human Molecular Genetics, p. 2121-2123, 2023

• DOI for Letter to the editor

Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog

Zhang, Qiang; Balourdas, Dimitrios-Ilias; Baron, Bruno; Senitzki, Alon et al.

Part of Cell Death and Disease, 2022

• DOI for Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog
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Colorectal Cancer Is Associated with the Presence of Cancer Driver Mutations in Normal Colon

Matas, Julia; Kohrn, Brendan; Fredrickson, Jeanne; Carter, Kelly et al.

Part of Cancer Research, p. 1492-1502, 2022

• DOI for Colorectal Cancer Is Associated with the Presence of Cancer Driver Mutations in Normal Colon

TP53 mutations at codon 234 are associated with chlorambucil treatment in chronic lymphocytic leukemia

Lazarian, Gregory; Theves, Floriane; Hormi, Myriam; Letestu, Remi et al.

Part of American Journal of Hematology, 2022

• DOI for TP53 mutations at codon 234 are associated with chlorambucil treatment in chronic lymphocytic leukemia

Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene

Doffe, Flora; Carbonnier, Vincent; Tissier, Manon; Leroy, Bernard et al.

Part of Cell Death and Differentiation, p. 1477-1492, 2021

• DOI for Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene
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Prevalence, distribution and predictive value of XPO1 mutation in a real-life chronic lymphocytic leukaemia cohort.

Tueur, Giulia; Lazarian, Gregory; Eclache, Virginie; Fleury, Carole et al.

Part of British Journal of Haematology, 2020

• DOI for Prevalence, distribution and predictive value of XPO1 mutation in a real-life chronic lymphocytic leukaemia cohort.

The TP53 tumor suppressor gene: From molecular biology to clinical investigations

Baliakas, Panagiotis; Soussi, Thierry

Part of Journal of Internal Medicine, p. 78-96, 2025

• DOI for The TP53 tumor suppressor gene: From molecular biology to clinical investigations
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TP53: the unluckiest of genes?

Joerger, Andreas C.; Stiewe, Thorsten; Soussi, Thierry

Part of Cell Death and Differentiation, p. 219-224, 2025

• DOI for TP53: the unluckiest of genes?
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ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-2024 update

Malcikova, Jitka; Pavlova, Sarka; Baliakas, Panagiotis; Chatzikonstantinou, Thomas et al.

Part of Leukemia, p. 1455-1468, 2024

• DOI for ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-2024 update
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Benign SNPs in the Coding Region of TP53: Finding the Needles in a Haystack of Pathogenic Variants

Soussi, Thierry

Part of Cancer Research, p. 3420-3431, 2022

• DOI for Benign SNPs in the Coding Region of TP53: Finding the Needles in a Haystack of Pathogenic Variants

Landscape of TP53 Alterations in Chronic Lymphocytic Leukemia via Data Mining Mutation Databases

Soussi, Thierry; Baliakas, Panagiotis

Part of Frontiers in Oncology, 2022

• DOI for Landscape of TP53 Alterations in Chronic Lymphocytic Leukemia via Data Mining Mutation Databases
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