Neeraj Katiyar

Short presentation

Neeraj joined the EMBLA group in May 2022 as a postdoctoral fellow. His research centers on developing on-chip culture platforms to explore how physical cues affect cells. He plays a key role in the EU's ERC PHOENIX project, which uses droplet acoustofluidics to create vascularized brain organoids for brain modeling. He also contributes to CNS×3, a Swedish research center in Uppsala focused on person-centered brain-on-chip models to accelerate data-driven therapeutic research for brain diseases.

Keywords

• Precision medicine
• 3D cell cultures
• Micro- and Nanofabrication
• Microfluidics
• Mechanobiology
• Nanobiotechnology

Biography

• 2022 - Present: Postdoctoral Fellow, EMBLA research group, Uppsala University
• 2022: Research Associate, Institute of Nano Science and Technology (INST), India
• 2021: PhD in Medical Science (Nanoscience & Technology), Amrita Vishwa Vidyapeetham University, India. Thesis "Axonal transport of topically applied gold nanoparticles in the sensory neurons of dorsal root ganglion."

Research

Neeraj's research centers on the development of microfluidic platforms, or organ-on-a-chip technologies, which offer a promising alternative to traditional animal models. By integrating 3D cell cultures with microfluidic systems, he creates in vivo-like environments to study cellular responses to various stimuli, a crucial step that could revolutionize drug discovery and development.

His current projects include:

• European Union's ERC PHOENIX project: Evaluation and development of vascularized brain organoids using droplet acoustofluidics to establish a reliable in vitro model of the human brain.
• CNS×3 project: Development of a microrheological system for creating perfusable, vascularized brain organoids derived from patient cells. This allows for extended culture and controlled drug testing without core necrosis, crucial for advancing therapeutic research for brain diseases.
• Organ-on-a-Chip Development: Designing platforms to study the influence of fluid shear stress on cellular physiology and function.
• 3D Micro-Barrier Culture Systems: Creating platforms that enable the investigation of how chemical gradients regulate cellular behavior in three-dimensional environments.

Media

Linkedln

https://www.linkedin.com/in/neeraj-katiyar-a1a07157/

ORCID

https://orcid.org/0000-0003-1809-5397