Axel Leppert

Allosteric targeting with antiviral nucleotide analogs allows fine-tuning of SAMHD1 dNTPase activity

Dirks, Christopher; Schlotterbeck, Ann-Kathrin; Pettersson, Pontus; Leppert, Axel et al.

Part of Journal of Biological Chemistry, 2026

• DOI for Allosteric targeting with antiviral nucleotide analogs allows fine-tuning of SAMHD1 dNTPase activity
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Intrinsically colored artificial silk fibers made from mini-spidroin fusion proteins

Bohn Pessatti, Tomas; Schmuck, Benjamin; Greco, Gabriele; Stadlmayr, Sarah et al.

Part of Communications Materials, 2026

• DOI for Intrinsically colored artificial silk fibers made from mini-spidroin fusion proteins
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Single-molecule mass measurements reveal distinct effects of sodium and potassium on mini-spidroin assembly

Osterholz, Hannah; Jeyalekshmy, Shree Senthil; Schmuck, Benjamin; Bohn Pessatti, Tomas et al.

Part of Communications Materials, 2026

• DOI for Single-molecule mass measurements reveal distinct effects of sodium and potassium on mini-spidroin assembly
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Chaperone-Mediated Regulation of Tau Phase Separation, Fibrillation, and Toxicity

Morman, Cecilia; Leppert, Axel; Pizzirusso, Giusy; Zheng, Zihan et al.

Part of Journal of the American Chemical Society, p. 23504-23518, 2025

• DOI for Chaperone-Mediated Regulation of Tau Phase Separation, Fibrillation, and Toxicity
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Helicobacter pylori CagA protein is a potent and broad-spectrum amyloid inhibitor

Jin, Zhen; Pallisgaard Olsen, William; Mörman, Cecilia; Leppert, Axel et al.

Part of Science Advances, 2025

• DOI for Helicobacter pylori CagA protein is a potent and broad-spectrum amyloid inhibitor
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Allosteric targeting with antiviral nucleotide analogs allows fine-tuning of SAMHD1 dNTPase activity

Dirks, Christopher; Schlotterbeck, Ann-Kathrin; Pettersson, Pontus; Leppert, Axel et al.

Part of Journal of Biological Chemistry, 2026

• DOI for Allosteric targeting with antiviral nucleotide analogs allows fine-tuning of SAMHD1 dNTPase activity
• Download full text (pdf) of Allosteric targeting with antiviral nucleotide analogs allows fine-tuning of SAMHD1 dNTPase activity

Intrinsically colored artificial silk fibers made from mini-spidroin fusion proteins

Bohn Pessatti, Tomas; Schmuck, Benjamin; Greco, Gabriele; Stadlmayr, Sarah et al.

Part of Communications Materials, 2026

• DOI for Intrinsically colored artificial silk fibers made from mini-spidroin fusion proteins
• Download full text (pdf) of Intrinsically colored artificial silk fibers made from mini-spidroin fusion proteins

Single-molecule mass measurements reveal distinct effects of sodium and potassium on mini-spidroin assembly

Osterholz, Hannah; Jeyalekshmy, Shree Senthil; Schmuck, Benjamin; Bohn Pessatti, Tomas et al.

Part of Communications Materials, 2026

• DOI for Single-molecule mass measurements reveal distinct effects of sodium and potassium on mini-spidroin assembly
• Download full text (pdf) of Single-molecule mass measurements reveal distinct effects of sodium and potassium on mini-spidroin assembly

Chaperone-Mediated Regulation of Tau Phase Separation, Fibrillation, and Toxicity

Morman, Cecilia; Leppert, Axel; Pizzirusso, Giusy; Zheng, Zihan et al.

Part of Journal of the American Chemical Society, p. 23504-23518, 2025

• DOI for Chaperone-Mediated Regulation of Tau Phase Separation, Fibrillation, and Toxicity
• Download full text (pdf) of Chaperone-Mediated Regulation of Tau Phase Separation, Fibrillation, and Toxicity

Helicobacter pylori CagA protein is a potent and broad-spectrum amyloid inhibitor

Jin, Zhen; Pallisgaard Olsen, William; Mörman, Cecilia; Leppert, Axel et al.

Part of Science Advances, 2025

• DOI for Helicobacter pylori CagA protein is a potent and broad-spectrum amyloid inhibitor
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Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains

Osterholz, Hannah; Stevens, Alexander; Abramsson, Mia L.; Lama, Dilraj et al.

Part of JACS Au, p. 281-290, 2025

• DOI for Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains
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Controlling Drug Partitioning in Individual Protein Condensates through Laser-Induced Microscale Phase Transitions

Leppert, Axel; Feng, Jianhui; Railaite, Vaida; Pessatti, Tomas Bohn et al.

Part of Journal of the American Chemical Society, p. 19555-19565, 2024

• DOI for Controlling Drug Partitioning in Individual Protein Condensates through Laser-Induced Microscale Phase Transitions
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Liquid-liquid crystalline phase separation of spider silk proteins

Landreh, Michael; Osterholz, Hannah; Chen, Gefei; Knight, Stefan D. et al.

Part of Communications Chemistry, 2024

• DOI for Liquid-liquid crystalline phase separation of spider silk proteins
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