Jan-Bernd Stukenborg
Senior Lecturer/Associate Professor at Department of Organismal Biology; Physiology and Environmental Toxicology
- Telephone:
- +46 73 469 70 20, +46 18 471 55 28
- E-mail:
- jan-bernd.stukenborg@ebc.uu.se
- Visiting address:
- Evolutionsbiologiskt Centrum EBC
Norbyvägen 18 A - Postal address:
- Norbyvägen 18 A
752 36 Uppsala
- CV:
- Download CV
Short presentation
I currently hold the position of Senior Lecturer and Group Leader at the NORDFERTIL Research Lab, within the Department of Organismal Biology at Uppsala University, and am an affiliated researcher at Karolinska Institutet in Stockholm, Sweden. Additionally, I serve as the Research Coordinator for NORDFERTIL (www.nordfertil.org). My research primarily focuses on fertility preservation techniques, with particular emphasis on in vitro differentiation methods, including innovative cell cultures.
Keywords
- fertility preservation techniques
- testis
- germ cells
- stem cells
- cell biology
- endocrinology
Biography
COURSES AND DEGREES
2001 – 2005: Biology, Westphalian Wilhelms University (WWU), Münster, Germany
2005: Diploma Thesis (Master Thesis; Biology), Centre of Reproductive Medicine and Andrology (CeRA), WWU, Münster, Germany & University of Pittsburgh, USA
2005 – 2009: PhD studies (Biology), CeRA, WWU, Münster, Germany
DOCTORAL DEGREE
2009: PhD in Biology (Reproductive Biology), Thesis: “In vitro differentiation of male germ cells,” CeRA, WWU, Münster, Germany; supervised by Prof. Dr E. Liebau and Prof. Dr S. Schlatt
POSTDOCTORAL APPOINTMENTS
2009 – 2013: Postdoctoral Researcher, Department of Women’s and Children’s Health, Paediatric Endocrinology Unit, Karolinska Institutet; supervised by Prof. Dr Olle Söder
DOCENT-LEVEL COMPETENCE
2016: Docent in Reproductive Biology, Karolinska Institutet
PRIOR POSITIONS
Jun. 2021 – Jun. 2025: Senior Lecturer (Associate Professor) in Experimental Reproductive Biology and Medicine (permanent position; 100% research), Childhood Cancer Research Unit, Department of Women’s and Children’s Health, Karolinska Institutet
Apr. 2019 – Jun. 2025: Group Leader, Childhood Cancer Research Unit, Department of Women’s and Children’s Health, Karolinska Institutet
Jan. 2019 – May 2021: Senior Researcher in Reproductive Physiology (permanent position; 100% research), Department of Women’s and Children’s Health, Karolinska Institutet
Mar. 2013 – Dec. 2018: Senior Research Specialist, Department of Women’s and Children’s Health, Karolinska Institutet
Research
Our research group focuses on germ cell differentiation both in vivo and in vitro, with a particular emphasis on fertility preservation techniques for children affected by gonadal dysfunctions. Central to our work is the investigation of testicular biology, including the behaviour of germ cells and their interaction with the somatic environment. We develop and apply advanced in vitro differentiation methods, employing novel cell culture systems that incorporate human and animal gonadal cells, human embryonic stem cells (hESCs), and human induced pluripotent stem cells (hiPSCs). This interdisciplinary research sits at the intersection of cell biology, stem cell science, and endocrinology, with the ultimate goal of understanding and restoring reproductive potential.

Publications
Recent publications
Part of npj Microgravity, 2025
Part of Advanced Science, 2025
- DOI for X-Linked Gene Dosage and SOX2 Act as Key Roadblocks for Human Germ Cell Specification in Klinefelter Syndrome
- Download full text (pdf) of X-Linked Gene Dosage and SOX2 Act as Key Roadblocks for Human Germ Cell Specification in Klinefelter Syndrome
The use of testicular organoids in advancing future treatments for male factor infertility
Part of Fertility and Sterility, p. 406-416, 2025
- DOI for The use of testicular organoids in advancing future treatments for male factor infertility
- Download full text (pdf) of The use of testicular organoids in advancing future treatments for male factor infertility
Part of Human Reproduction, p. 1467-1475, 2025
- DOI for Early transcriptional states of spermatogonia and marker expressions in the prepubertal human testis following chemotherapy-induced depletion
- Download full text (pdf) of Early transcriptional states of spermatogonia and marker expressions in the prepubertal human testis following chemotherapy-induced depletion
Part of Human Reproduction, p. 1391-1431, 2025
- DOI for ESHRE good practice recommendations on fertility preservation involving testicular tissue cryopreservation in children receiving gonadotoxic therapies
- Download full text (pdf) of ESHRE good practice recommendations on fertility preservation involving testicular tissue cryopreservation in children receiving gonadotoxic therapies
All publications
Articles in journal
Part of npj Microgravity, 2025
Part of Advanced Science, 2025
- DOI for X-Linked Gene Dosage and SOX2 Act as Key Roadblocks for Human Germ Cell Specification in Klinefelter Syndrome
- Download full text (pdf) of X-Linked Gene Dosage and SOX2 Act as Key Roadblocks for Human Germ Cell Specification in Klinefelter Syndrome
Part of Human Reproduction, p. 1467-1475, 2025
- DOI for Early transcriptional states of spermatogonia and marker expressions in the prepubertal human testis following chemotherapy-induced depletion
- Download full text (pdf) of Early transcriptional states of spermatogonia and marker expressions in the prepubertal human testis following chemotherapy-induced depletion
Part of Human Reproduction, p. 1391-1431, 2025
- DOI for ESHRE good practice recommendations on fertility preservation involving testicular tissue cryopreservation in children receiving gonadotoxic therapies
- Download full text (pdf) of ESHRE good practice recommendations on fertility preservation involving testicular tissue cryopreservation in children receiving gonadotoxic therapies
Part of Baillière's Best Practice & Research, 2025
- DOI for Is the time right for transplanting immature testicular tissue or cells to restore male fertility?: Expert perspectives on clinical implementation of autotransplantation of cryopreserved testicular tissue or cells for fertility restoration
- Download full text (pdf) of Is the time right for transplanting immature testicular tissue or cells to restore male fertility?: Expert perspectives on clinical implementation of autotransplantation of cryopreserved testicular tissue or cells for fertility restoration
Part of REPRODUCTION AND FERTILITY, 2025
Decreased spermatogonial numbers in boys with severe haematological diseases.
Part of British Journal of Haematology, p. 229-235, 2024
- DOI for Decreased spermatogonial numbers in boys with severe haematological diseases.
- Download full text (pdf) of Decreased spermatogonial numbers in boys with severe haematological diseases.
Articles, review/survey
The use of testicular organoids in advancing future treatments for male factor infertility
Part of Fertility and Sterility, p. 406-416, 2025
- DOI for The use of testicular organoids in advancing future treatments for male factor infertility
- Download full text (pdf) of The use of testicular organoids in advancing future treatments for male factor infertility