Helgi Birgisson

Postoperative complications and prognosis after splenectomy during cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

Ghanipour, Lana; Rashed, Mariam; Abraham-Nordling, Mirna; Enblad, Malin et al.

Part of European Journal of Surgical Oncology, 2026

• DOI for Postoperative complications and prognosis after splenectomy during cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

The Extent of Tumor in the Peritoneum and Liver Influences Outcomes After Surgery for Synchronous Liver and Peritoneal Colorectal Metastases: A Cohort Study

Sanchez Salas, Pearl; Urdzik, Jozef; Graf, Wilhelm; Isaksson, Bengt et al.

Part of Journal of Gastrointestinal Cancer, 2025

• DOI for The Extent of Tumor in the Peritoneum and Liver Influences Outcomes After Surgery for Synchronous Liver and Peritoneal Colorectal Metastases: A Cohort Study
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Prognostic genome and transcriptome signatures in colorectal cancers

Nunes, Luís; Li, Fuqiang; Wu, Meizhen; Luo, Tian et al.

Part of Nature, p. 137-146, 2024

• DOI for Prognostic genome and transcriptome signatures in colorectal cancers
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Clinical significance of circulating tumor cells in colorectal cancer with peritoneal metastases: a prospective cohort study using a novel method for monitoring treatment response, and assessing minimal residual disease

Frühling, Petter; Moberg, Louice; Ghanipour, Lana; Birgisson, Helgi et al.

Part of International Journal of Surgery, p. 7187-7195, 2024

• DOI for Clinical significance of circulating tumor cells in colorectal cancer with peritoneal metastases: a prospective cohort study using a novel method for monitoring treatment response, and assessing minimal residual disease
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Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Metastases from Colorectal Cancer-An Overview of Current Status and Future Perspectives

Graf, Wilhelm; Ghanipour, Lana; Birgisson, Helgi; Cashin, Peter

Part of Cancers, 2024

• DOI for Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Metastases from Colorectal Cancer-An Overview of Current Status and Future Perspectives
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Postoperative complications and prognosis after splenectomy during cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

Ghanipour, Lana; Rashed, Mariam; Abraham-Nordling, Mirna; Enblad, Malin et al.

Part of European Journal of Surgical Oncology, 2026

• DOI for Postoperative complications and prognosis after splenectomy during cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

The Extent of Tumor in the Peritoneum and Liver Influences Outcomes After Surgery for Synchronous Liver and Peritoneal Colorectal Metastases: A Cohort Study

Sanchez Salas, Pearl; Urdzik, Jozef; Graf, Wilhelm; Isaksson, Bengt et al.

Part of Journal of Gastrointestinal Cancer, 2025

• DOI for The Extent of Tumor in the Peritoneum and Liver Influences Outcomes After Surgery for Synchronous Liver and Peritoneal Colorectal Metastases: A Cohort Study
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Prognostic genome and transcriptome signatures in colorectal cancers

Nunes, Luís; Li, Fuqiang; Wu, Meizhen; Luo, Tian et al.

Part of Nature, p. 137-146, 2024

• DOI for Prognostic genome and transcriptome signatures in colorectal cancers
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Clinical significance of circulating tumor cells in colorectal cancer with peritoneal metastases: a prospective cohort study using a novel method for monitoring treatment response, and assessing minimal residual disease

Frühling, Petter; Moberg, Louice; Ghanipour, Lana; Birgisson, Helgi et al.

Part of International Journal of Surgery, p. 7187-7195, 2024

• DOI for Clinical significance of circulating tumor cells in colorectal cancer with peritoneal metastases: a prospective cohort study using a novel method for monitoring treatment response, and assessing minimal residual disease
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A Validation of the Swedish Colorectal Cancer Register - With Focus on Histopathology, Complications and Recurrences

Arnarson, Orvar; Moberger, Peter; Sköldberg, Filip; Smedh, Kenneth et al.

Part of Clinical Epidemiology, p. 525-532, 2024

• DOI for A Validation of the Swedish Colorectal Cancer Register - With Focus on Histopathology, Complications and Recurrences
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Omental metastases in patients with pseudomyxoma peritonei or colorectal peritoneal metastases - is routine omentectomy justified?

Enblad, Malin; Birgisson, Helgi; Ghanipour, Lana; Cashin, Peter et al.

Part of International Journal of Hyperthermia, 2024

• DOI for Omental metastases in patients with pseudomyxoma peritonei or colorectal peritoneal metastases - is routine omentectomy justified?

Clinical Significance of Circulating Tumor Cells in Epithelial Appendiceal Neoplasms with Peritoneal Metastases

Frühling, Petter; Moberg, Louice; Ghanipour, Lana; Birgisson, Helgi et al.

Part of Cancers, 2024

• DOI for Clinical Significance of Circulating Tumor Cells in Epithelial Appendiceal Neoplasms with Peritoneal Metastases
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No Indication for Routine Resection of Surgical Scars during Cytoreductive Surgery and HIPEC

Enblad, Malin; Ghanipour, Lana; Cashin, Peter; Birgisson, Helgi et al.

Part of Cancers, 2024

• DOI for No Indication for Routine Resection of Surgical Scars during Cytoreductive Surgery and HIPEC
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Efficacy of hyperthermic intraperitoneal chemotherapy in colorectal cancer: A phase I and III open label randomized controlled registry-based clinical trial protocol

Ghanipour, Lana; Jansson Palmer, Gabriella; Nilsson, Per J.; Nordenvall, Caroline et al.

Part of PLOS ONE, 2024

• DOI for Efficacy of hyperthermic intraperitoneal chemotherapy in colorectal cancer: A phase I and III open label randomized controlled registry-based clinical trial protocol
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Signet Ring Cell Colorectal and Appendiceal Cancer: A Small Signet Ring Cell Component Is Also Associated with Poor Outcome

Enblad, Malin; Pál Egerszegi, Péter; Birgisson, Helgi; Sjöblom, Tobias et al.

Part of Cancers, 2023

• DOI for Signet Ring Cell Colorectal and Appendiceal Cancer: A Small Signet Ring Cell Component Is Also Associated with Poor Outcome
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Noninvasive detection of any-stage cancer using free glycosaminoglycans

Bratulic, Sinisa; Limeta, Angelo; Dabestani, Saeed; Birgisson, Helgi et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2022

• DOI for Noninvasive detection of any-stage cancer using free glycosaminoglycans
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Oxaliplatin-based hyperthermic intraperitoneal chemotherapy with single drug versus multiple drug treatment for colorectal cancer with peritoneal metastases: an observational cohort study

Frühling, Petter; Ghanipour, Lana; Dranichnikov, Paul; Enblad, Malin et al.

Part of Journal of Gastrointestinal Oncology, p. 516-526, 2021

• DOI for Oxaliplatin-based hyperthermic intraperitoneal chemotherapy with single drug versus multiple drug treatment for colorectal cancer with peritoneal metastases: an observational cohort study
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Prognostic Impact of BRAF and KRAS Mutation in Patients with Colorectal and Appendiceal Peritoneal Metastases Scheduled for CRS and HIPEC

Graf, Wilhelm; Cashin, Peter; Ghanipour, Lana; Enblad, Malin et al.

Part of Annals of Surgical Oncology, p. 293-300, 2020

• DOI for Prognostic Impact of BRAF and KRAS Mutation in Patients with Colorectal and Appendiceal Peritoneal Metastases Scheduled for CRS and HIPEC
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ASO Author Reflections: Can Patient Selection for Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy be Improved?

Graf, Wilhelm; Birgisson, Helgi

Part of Annals of Surgical Oncology, p. 301-302, 2020

• DOI for ASO Author Reflections: Can Patient Selection for Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy be Improved?
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Patients with colorectal peritoneal metastases and high peritoneal cancer index may benefit from cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

Birgisson, Helgi; Enblad, Malin; Artursson, Sara; Ghanipour, Lana et al.

Part of European Journal of Surgical Oncology, p. 2283-2291, 2020

• DOI for Patients with colorectal peritoneal metastases and high peritoneal cancer index may benefit from cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
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Gains of Chromosome 1p and 15q are Associated with Poor Survival After Cytoreductive Surgery and HIPEC for Treating Colorectal Peritoneal Metastases

Enblad, Malin; Graf, Wilhelm; Terman, Alexei; Pucholt, Pascal et al.

Part of Annals of Surgical Oncology, p. 4835-4842, 2019

• DOI for Gains of Chromosome 1p and 15q are Associated with Poor Survival After Cytoreductive Surgery and HIPEC for Treating Colorectal Peritoneal Metastases
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U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

Glimelius, Bengt; Melin, Beatrice; Enblad, Gunilla; Alafuzoff, Irina et al.

Part of Acta Oncologica, p. 187-194, 2018

• DOI for U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.
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Risk factors for appendiceal and colorectal peritoneal metastases

Enblad, Malin; Graf, Wilhelm; Birgisson, Helgi

Part of European Journal of Surgical Oncology, p. 997-1005, 2018

• DOI for Risk factors for appendiceal and colorectal peritoneal metastases

Evaluation of the Swedish Colorectal Cancer Registry: an overview of completeness, timeliness, comparability and validity

Moberger, Peter; Sköldberg, Filip; Birgisson, Helgi

Part of Acta Oncologica, p. 1611-1621, 2018

• DOI for Evaluation of the Swedish Colorectal Cancer Registry: an overview of completeness, timeliness, comparability and validity
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Plasma Protein Profiling Reveal Osteoprotegerin as a Marker of Prognostic Impact for Colorectal Cancer

Birgisson, H; Tsimogiannis, Kostas; Freyhult, Eva; Kamali-Moghaddam, Masood

Part of Translational Oncology, p. 1034-1043, 2018

• DOI for Plasma Protein Profiling Reveal Osteoprotegerin as a Marker of Prognostic Impact for Colorectal Cancer
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Highly sensitive and specific protein detection via combined capillary isoelectric focusing and proximity ligation

Padhan, Narendra; Yan, Junhong; Boge, Annegret; Scrivener, Elaine et al.

Part of Scientific Reports, 2017

• DOI for Highly sensitive and specific protein detection via combined capillary isoelectric focusing and proximity ligation
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Associations of defect mismatch repair genes with prognosis and heredity in sporadic colorectal cancer

Ghanipour, Lana; Jirström, Karin; Sundström, Magnus; Glimelius, Bengt et al.

Part of European Journal of Surgical Oncology, p. 311-321, 2017

• DOI for Associations of defect mismatch repair genes with prognosis and heredity in sporadic colorectal cancer

Somatic Ephrin Receptor Mutations Are Associated with Metastasis in Primary Colorectal Cancer

Mathot, Lucy; Kundu, Snehangshu; Ljungström, Viktor; Svedlund, Jessica et al.

Part of Cancer Research, p. 1730-1740, 2017

• DOI for Somatic Ephrin Receptor Mutations Are Associated with Metastasis in Primary Colorectal Cancer

Increased incidence of bowel cancer after non-surgical treatment of appendicitis

Enblad, Malin; Birgisson, H; Ekbom, Anders; Sandin, Fredrik et al.

Part of European Journal of Surgical Oncology, p. 2067-2075, 2017

• DOI for Increased incidence of bowel cancer after non-surgical treatment of appendicitis

Risk of second primary cancer in patients treated with radiotherapy for rectal cancer

Martling, A.; Smedby, K. E.; Birgisson, Helgi; Olsson, H. et al.

Part of British Journal of Surgery, p. 278-287, 2017

• DOI for Risk of second primary cancer in patients treated with radiotherapy for rectal cancer

High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer

Padhan, Narendra; Nordling, Torbjorn E. M.; Sundström, Magnus; Åkerud, Peter et al.

Part of BMC Cancer, 2016

• DOI for High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer
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Significant association and synergistic adverse prognostic effect of podocalyxin-like protein and epidermal growth factor receptor expression in colorectal cancer

Larsson, Anna H.; Lehn, Sophie; Wangefjord, Sakarias; Karnevi, Emelie et al.

Part of Journal of Translational Medicine, 2016

• DOI for Significant association and synergistic adverse prognostic effect of podocalyxin-like protein and epidermal growth factor receptor expression in colorectal cancer
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Importance of Absent Neoplastic Epithelium in Patients Treated With Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

Enblad, Malin; Birgisson, Helgi; Wanders, Alkwin; Sköldberg, Filip et al.

Part of Annals of Surgical Oncology, p. 1149-1156, 2016

• DOI for Importance of Absent Neoplastic Epithelium in Patients Treated With Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

Detection of prognostic biomarkers with solid-phase proximity ligation assay in patients with colorectal cancer

Ghanipour, Lana; Darmanis, Spyros; Landegren, Ulf; Glimelius, Bengt et al.

Part of Translational Oncology, p. 251-255, 2016

• DOI for Detection of prognostic biomarkers with solid-phase proximity ligation assay in patients with colorectal cancer
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Complications Related To Surgery For Ovarian Cancer With Intestinal Involvement

Lomnytska, M.; Stalberg, Karin; Birgisson, Helgi; Silins, Ilvars et al.

Part of International Journal of Gynecological Cancer, p. 492-492, 2015

Microsatellite instability and mutations in BRAF and KRAS are significant predictors of disseminated disease in colon cancer

Birgisson, Helgi; Edlund, Karolina; Wallin, Ulrik; Påhlman, Lars et al.

Part of BMC Cancer, 2015

• DOI for Microsatellite instability and mutations in BRAF and KRAS are significant predictors of disseminated disease in colon cancer
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Time trends, improvements and national auditing of rectal cancer management over an 18-year period

Kodeda, K.; Johansson, R.; Zar, N.; Birgisson, Helgi et al.

Part of Colorectal Disease, 2015

• DOI for Time trends, improvements and national auditing of rectal cancer management over an 18-year period

1p36 deletion is a marker for tumour dissemination in microsatellite stable stage II-III colon cancer

Mayrhofer, Markus; Kultima, Hanna Göransson; Birgisson, Helgi; Sundström, Magnus et al.

Part of BMC Cancer, p. 872, 2014

• DOI for 1p36 deletion is a marker for tumour dissemination in microsatellite stable stage II-III colon cancer
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STC1 Expression By Cancer-Associated Fibroblasts Drives Metastasis of Colorectal Cancer

Pena, Cristina; Virtudes Cespedes, Maria; Lindh, Maja Bradic; Kiflemariam, Sara et al.

Part of Cancer Research, p. 1287-1297, 2013

• DOI for STC1 Expression By Cancer-Associated Fibroblasts Drives Metastasis of Colorectal Cancer

Validation of podocalyxin-like protein as a biomarker of poor prognosis in colorectal cancer

Larsson, Anna; Fridberg, Marie; Gaber, Alexander; Nodin, Björn et al.

Part of BMC Cancer, p. 282, 2012

• DOI for Validation of podocalyxin-like protein as a biomarker of poor prognosis in colorectal cancer
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Serum concentrations of human chorionic gonadotropin beta and its association with survival in patients with colorectal cancer

Birgisson, Helgi; Jirström, Karin; Stenman, Ulf-Håkan

Part of CANCER BIOMARK, p. 173-181, 2012

• DOI for Serum concentrations of human chorionic gonadotropin beta and its association with survival in patients with colorectal cancer

Allele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity

Rasmussen, Markus; Sundström, Magnus; Kultima, Hanna Göransson; Botling, Johan et al.

Part of Genome Biology, 2011

• DOI for Allele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity
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Survival endpoints in colorectal cancer and the effect of second primary other cancer on disease free survival

Birgisson, Helgi; Wallin, Ulrik; Holmberg, Lars; Glimelius, Bengt

Part of BMC Cancer, p. 438, 2011

• DOI for Survival endpoints in colorectal cancer and the effect of second primary other cancer on disease free survival
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SATB2 in Combination With Cytokeratin 20 Identifies Over 95% of all Colorectal Carcinomas

Magnusson, Kristina; de Wit, Meike; Brennan, Donal J.; Johnson, Louis B. et al.

Part of American Journal of Surgical Pathology, p. 937-948, 2011

• DOI for SATB2 in Combination With Cytokeratin 20 Identifies Over 95% of all Colorectal Carcinomas

Growth differentiation factor 15: a prognostic marker for recurrence in colorectal cancer

Wallin, Ulrik; Glimelius, Bengt; Jirström, K.; Darmanis, Spyros et al.

Part of British Journal of Cancer, p. 1619-1627, 2011

• DOI for Growth differentiation factor 15: a prognostic marker for recurrence in colorectal cancer

KRAS analysis in colorectal carcinoma: analytical aspects of Pyrosequencing and allele-specific PCR in clinical practice

Sundström, Magnus; Edlund, Karolina; Lindell, Monica; Glimelius, Bengt et al.

Part of BMC Cancer, p. 660, 2010

• DOI for KRAS analysis in colorectal carcinoma: analytical aspects of Pyrosequencing and allele-specific PCR in clinical practice

Increased serum levels of tumour-associated trypsin inhibitor independently predict a poor prognosis in colorectal cancer patients

Gaber, Alexander; Nodin, Björn; Hotakainen, Kristina; Nilsson, Elise et al.

Part of BMC Cancer, p. 498, 2010

• DOI for Increased serum levels of tumour-associated trypsin inhibitor independently predict a poor prognosis in colorectal cancer patients

Preoperative plasma TIMP-1 is an independent prognostic indicator in patients with primary colorectal cancer: a prospective validation study

Birgisson, Helgi; Nielsen, Hans J.; Christensen, Ib Jarle; Glimelius, Bengt et al.

Part of European Journal of Cancer, p. 3323-3331, 2010

• DOI for Preoperative plasma TIMP-1 is an independent prognostic indicator in patients with primary colorectal cancer: a prospective validation study

The correlation between a family history of colorectal cancer and survival of patients with colorectal cancer

Birgisson, Helgi; Ghanipour, Arezo; Smedh, Kennet; Påhlman, Lars et al.

Part of Familial Cancer, p. 555-561, 2009

• DOI for The correlation between a family history of colorectal cancer and survival of patients with colorectal cancer

High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer

Gaber, A.; Johansson, M.; Stenman, U-H.; Hotakainen, K. et al.

Part of British Journal of Cancer, p. 1540-1548, 2009

• DOI for High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer

The prognostic significance of tryptophanyl-tRNA synthetase in colorectal cancer

Ghanipour, Arezo; Jirström, Karin; Pontén, Fredrik; Glimelius, Bengt et al.

Part of Cancer Epidemiology, Biomarkers and Prevention, p. 2949-2956, 2009

• DOI for The prognostic significance of tryptophanyl-tRNA synthetase in colorectal cancer

Authors' reply: Late gastrointestinal disorders after rectal cancer surgery with and without preoperative radiation therapy (Br J Surg 2008; 95 : 206-213)

Birgisson, Helgi; Påhlman, Lars; Gunnarsson, U.; Glimelius, B.

Part of British Journal of Surgery, p. 803-803, 2008

• DOI for Authors' reply: Late gastrointestinal disorders after rectal cancer surgery with and without preoperative radiation therapy (Br J Surg 2008; 95 : 206-213)

Late adverse effects of radiation therapy for rectal cancer: a systematic overview

Birgisson, Helgi; Påhlman, Lars; Gunnarsson, Ulf; Glimelius, Bengt

Part of Acta Oncologica, p. 504-516, 2007

• DOI for Late adverse effects of radiation therapy for rectal cancer: a systematic overview

Swedish Rectal Cancer Trial: long lasting benefits from radiotherapy on survival and local recurrence rate.

Folkesson, Joakim; Birgisson, Helgi; Pahlman, Lars; Cedermark, Bjorn et al.

Part of J Clin Oncol, p. 5644-50, 2005

Improved survival in cancer of the colon and rectum in Sweden.

Birgisson, H; Talbäck, M; Gunnarsson, U; Påhlman, L et al.

Part of Eur J Surg Oncol, p. 845-53, 2005

Adverse effects of preoperative radiation therapy for rectal cancer: long-term follow-up of the Swedish Rectal Cancer Trial.

Birgisson, Helgi; Pahlman, Lars; Gunnarsson, Ulf; Glimelius, Bengt

Part of J Clin Oncol, p. 8697-705, 2005

Occurrence of second cancers in patients treated with radiotherapy for rectal cancer.

Birgisson, Helgi; Pahlman, Lars; Gunnarsson, Ulf; Glimelius, Bengt

Part of J Clin Oncol, p. 6126-31, 2005

[Self-expanding stent in obstructing colorectal cancer. A new technique to avoid abdominal surgery]

Smedh, Kennet; Birgisson, Helgi; Raab, Yngve; Strand, Eva et al.

Part of Lakartidningen, p. 1982-6, 2003

Acute pancreatitis: a prospective study of its incidence, aetiology, severity and mortality in Iceland.

Birgisson, Helgi; Moller, PH; Birgisson, S; Thoroddsen, A et al.

Part of Eur J Surg, p. 278-82, 2002

Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Metastases from Colorectal Cancer-An Overview of Current Status and Future Perspectives

Graf, Wilhelm; Ghanipour, Lana; Birgisson, Helgi; Cashin, Peter

Part of Cancers, 2024

• DOI for Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Metastases from Colorectal Cancer-An Overview of Current Status and Future Perspectives
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Skimun fyrir krabbameinum í ristli og endaþarmi: Yfirlitsgrein um nýgengi, dánartíðni, kostnað og árangur

Birgisson, Helgi; Olafsdottir, Elinborg J.; Sverrisdottir, Anna; Einarsson, Sigurour et al.

Part of Laeknabladid, p. 398-405, 2021

• DOI for Skimun fyrir krabbameinum í ristli og endaþarmi: Yfirlitsgrein um nýgengi, dánartíðni, kostnað og árangur
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Prognostic importance of genetic alterations in colorectal peritoneal metastases

Enblad, Malin; Graf, Wilhelm; Terman, Alexei; Pucholt, Pascal et al.