Johan Heldin

Precise mapping of single-stranded DNA breaks by sequence-templated erroneous DNA polymerase end-labelling

Wenson, Leonie; Heldin, Johan; Martin, Marcel; Erbilgin, Yuecel et al.

Part of Nature Communications, 2025

• DOI for Precise mapping of single-stranded DNA breaks by sequence-templated erroneous DNA polymerase end-labelling
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Visualizing DNA single- and double-strand breaks in the Flash comet assay by DNA polymerase-assisted end-labelling

Bivehed, Erik; Hellman, Björn; Wenson, Leonie; Stenerlöw, Bo et al.

Part of Nucleic Acids Research, 2024

• DOI for Visualizing DNA single- and double-strand breaks in the Flash comet assay by DNA polymerase-assisted end-labelling
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Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation

Olsson, Frida; Wåhlén, Erik; Heldin, Johan; Söderberg, Ola et al.

Part of Biochemical and Biophysical Research Communications - BBRC, 2024

• DOI for Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation
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The method developer's guide to oligonucleotide design

Wenson, Leonie; Leino, Mattias; Jarvius, Malin; Heldin, Johan et al.

Part of Expert Review of Proteomics, p. 65-80, 2024

• DOI for The method developer's guide to oligonucleotide design
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Depletion of the Rho GTPases Cdc42, Rac1 or RhoA reduces PDGF-induced STAT1 and STAT3 signaling

Wåhlén, Erik; Lennartsson, Johan; Heldin, Johan

Part of Biochemistry and Biophysics Reports, 2024

• DOI for Depletion of the Rho GTPases Cdc42, Rac1 or RhoA reduces PDGF-induced STAT1 and STAT3 signaling
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Precise mapping of single-stranded DNA breaks by sequence-templated erroneous DNA polymerase end-labelling

Wenson, Leonie; Heldin, Johan; Martin, Marcel; Erbilgin, Yuecel et al.

Part of Nature Communications, 2025

• DOI for Precise mapping of single-stranded DNA breaks by sequence-templated erroneous DNA polymerase end-labelling
• Download full text (pdf) of Precise mapping of single-stranded DNA breaks by sequence-templated erroneous DNA polymerase end-labelling

Visualizing DNA single- and double-strand breaks in the Flash comet assay by DNA polymerase-assisted end-labelling

Bivehed, Erik; Hellman, Björn; Wenson, Leonie; Stenerlöw, Bo et al.

Part of Nucleic Acids Research, 2024

• DOI for Visualizing DNA single- and double-strand breaks in the Flash comet assay by DNA polymerase-assisted end-labelling
• Download full text (pdf) of Visualizing DNA single- and double-strand breaks in the Flash comet assay by DNA polymerase-assisted end-labelling

Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation

Olsson, Frida; Wåhlén, Erik; Heldin, Johan; Söderberg, Ola et al.

Part of Biochemical and Biophysical Research Communications - BBRC, 2024

• DOI for Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation
• Download full text (pdf) of Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation

Depletion of the Rho GTPases Cdc42, Rac1 or RhoA reduces PDGF-induced STAT1 and STAT3 signaling

Wåhlén, Erik; Lennartsson, Johan; Heldin, Johan

Part of Biochemistry and Biophysics Reports, 2024

• DOI for Depletion of the Rho GTPases Cdc42, Rac1 or RhoA reduces PDGF-induced STAT1 and STAT3 signaling
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PDGF-induced internalisation promotes proteolytic cleavage of PDGFRβ in mesenchymal cells

Rubin Sander, Marie; Tsiatsiou, Agni Karolina; Wang, Kehuan; Papadopoulos, Natalia et al.

Part of Growth Factors, p. 147-160, 2024

• DOI for PDGF-induced internalisation promotes proteolytic cleavage of PDGFRβ in mesenchymal cells
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Activated EGFR and PDGFR internalize in separate vesicles and downstream AKT and ERK1/2 signaling are differentially impacted by cholesterol depletion

Wåhlén, Erik; Olsson, Frida; Raykova, Doroteya; Söderberg, Ola et al.

Part of Biochemical and Biophysical Research Communications - BBRC, p. 195-201, 2023

• DOI for Activated EGFR and PDGFR internalize in separate vesicles and downstream AKT and ERK1/2 signaling are differentially impacted by cholesterol depletion
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Analysis of context-specific KRAS-effector (sub)complexes in Caco-2 cells

Ternet, Camille; Junk, Philipp; Sevrin, Thomas; Catozzi, Simona et al.

Part of Life Science Alliance, 2023

• DOI for Analysis of context-specific KRAS-effector (sub)complexes in Caco-2 cells
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A method for Boolean analysis of protein interactions at a molecular level

Raykova, Doroteya; Kermpatsou, Despoina; Malmqvist, Tony; Harrison, Philip J et al.

Part of Nature Communications, 2022

• DOI for A method for Boolean analysis of protein interactions at a molecular level
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Differential impact of lipid raft depletion on platelet-derived growth factor (PDGF)-induced ERK1/2 MAP-kinase, SRC and AKT signaling

Wåhlén, Erik; Olsson, Frida; Söderberg, Ola; Lennartsson, Johan et al.

Part of Cellular Signalling, 2022

• DOI for Differential impact of lipid raft depletion on platelet-derived growth factor (PDGF)-induced ERK1/2 MAP-kinase, SRC and AKT signaling
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Image-based high-throughput mapping of TGF-beta-induced phosphocomplexes at a single-cell level

Lönn, Peter; Al-Amin, Abdullah; Doulabi, Ehsan Manouchehri; Heldin, Johan et al.

Part of Communications Biology, 2021

• DOI for Image-based high-throughput mapping of TGF-beta-induced phosphocomplexes at a single-cell level
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Optimization of proximity-dependent initiation of hybridization chain reaction for improved performance

Leino, Mattias; Heldin, Johan; Rubin Sander, Marie; Kermpatsou, Despoina et al.

Part of Molecular Systems Design & Engineering, p. 1058-1065, 2019

• DOI for Optimization of proximity-dependent initiation of hybridization chain reaction for improved performance
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Dynamin inhibitors impair platelet-derived growth factor beta-receptor dimerization and signaling

Heldin, Johan; Rubin Sander, Marie; Leino, Mattias; Thomsson, Sara et al.

Part of Experimental Cell Research, p. 69-79, 2019

• DOI for Dynamin inhibitors impair platelet-derived growth factor beta-receptor dimerization and signaling
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Improved efficiency of in situ protein analysis by proximity ligation using UnFold probes

Klaesson, Axel; Grannas, Karin; Ebai, Tonge; Heldin, Johan et al.

Part of Scientific Reports, 2018

• DOI for Improved efficiency of in situ protein analysis by proximity ligation using UnFold probes
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Detection of post-translational modifications using solid-phase proximity ligation assay

de Oliveira, Felipe Marques Souza; Mereiter, Stefan; Lönn, Peter; Siart, Benjamin et al.

Part of New Biotechnology, p. 51-59, 2018

• DOI for Detection of post-translational modifications using solid-phase proximity ligation assay

FGD5 sustains vascular endothelial growth factor A (VEGFA) signaling through inhibition of proteasome-mediated VEGF receptor 2 degradation

Heldin, Johan; O'Callaghan, Paul; Hernández Vera, Rodrigo; Fredlund Fuchs, Peder et al.

Part of Cellular Signalling, p. 125-132, 2017

• DOI for FGD5 sustains vascular endothelial growth factor A (VEGFA) signaling through inhibition of proteasome-mediated VEGF receptor 2 degradation

The atypical Rho GTPase RhoD is a regulator of actin cytoskeleton dynamics and directed cell migration

Blom, Magdalena; Reis, Katarina; Heldin, Johan; Kreuger, Johan et al.

Part of Experimental Cell Research, p. 255-264, 2017

• DOI for The atypical Rho GTPase RhoD is a regulator of actin cytoskeleton dynamics and directed cell migration

Proximity-dependent initiation of hybridization chain reaction

Koos, Björn; Cane, Gaëlle; Grannas, Karin; Löf, Liza et al.

Part of Nature Communications, 2015

• DOI for Proximity-dependent initiation of hybridization chain reaction
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Interactions of zebrafish peptide YYb with the neuropeptide Y-family receptors Y4, Y7, Y8a, and Y8b

Sundström, Görel; Larsson, Tomas A.; Xu, Bo; Heldin, Johan et al.

Part of Frontiers in Neuroscience, 2013

• DOI for Interactions of zebrafish peptide YYb with the neuropeptide Y-family receptors Y4, Y7, Y8a, and Y8b
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Functional Overlap Between Chondroitin and Heparan Sulfate Proteoglycans During VEGF-Induced Sprouting Angiogenesis

Le Jan, Sébastien; Hayashi, Makoto; Kasza, Zsolt; Eriksson, Inger et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 1255-1263, 2012

• DOI for Functional Overlap Between Chondroitin and Heparan Sulfate Proteoglycans During VEGF-Induced Sprouting Angiogenesis

Characterization of the neuropeptide Y system in the frog Silurana tropicalis (Pipidae): three peptides and six receptor subtypes

Sundström, Görel; Xu, Bo; Larsson, Tomas A; Heldin, Johan et al.

Part of General and Comparative Endocrinology, p. 322-331, 2012

• DOI for Characterization of the neuropeptide Y system in the frog Silurana tropicalis (Pipidae): three peptides and six receptor subtypes

Exocyst Complex Component 3-like 2 (EXOC3L2) Associates with the Exocyst Complex and Mediates Directional Migration of Endothelial Cells

Barkefors, Irmeli; Fredlund Fuchs, Peder; Heldin, Johan; Bergström, Tobias et al.

Part of Journal of Biological Chemistry, p. 24189-24199, 2011

• DOI for Exocyst Complex Component 3-like 2 (EXOC3L2) Associates with the Exocyst Complex and Mediates Directional Migration of Endothelial Cells

Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1

Larsson, Erik; Fredlund Fuchs, Peder; Heldin, Johan; Barkefors, Irmeli et al.

Part of Genome Medicine, p. 108, 2009

• DOI for Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1

The method developer's guide to oligonucleotide design

Wenson, Leonie; Leino, Mattias; Jarvius, Malin; Heldin, Johan et al.

Part of Expert Review of Proteomics, p. 65-80, 2024

• DOI for The method developer's guide to oligonucleotide design
• Download full text (pdf) of The method developer's guide to oligonucleotide design

Identification and Characterization of Proteins and MicroRNAs that Modulate Receptor Signaling, Vesicular Trafficking and Cell Migration in Vascular Cells

Heldin, Johan

2014

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High-throughput in situ mapping of phosphorylated protein complexes across the cell cycle and in response to drugs

Lönn, Peter; Al-Amin, Rasel A.; Heldin, Johan; Gallini, Radiosa et al.