Jessica Nordlund

Midostaurin response in AML is shaped by a progenitor-like cell state selectively targeted by SMAC mimetics

Struyf, Nona; Gezelius, Henrik; Lundmark, Anders; Barizza, Chiara et al.

Part of npj Precision Oncology, 2026

DOI for Midostaurin response in AML is shaped by a progenitor-like cell state selectively targeted by SMAC mimetics
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Whole-genome sequencing with AVITI and NovaSeq X Plus reveals comparable performance with contextual biases

Höjer, Pontus; Alneberg, Johannes; Lundin, Pär; Martin, Tom et al.

Part of NAR Genomics and Bioinformatics, 2026

Author's Response to the Commentary by Raitoharju E et al. on "Epigenome-wide analysis across the development span of pediatric acute lymphoblastic leukemia: backtracking to birth"

Nassar, Farah J.; Cahais, Vincent; McKay, Jill A.; Strathdee, Gordon et al.

Part of Molecular Cancer, 2026

An integrative molecular map of pediatric B-cell precursor acute lymphoblastic leukemia

Krali, Olga; Enblad, Anna Pia; Sulyaeva, Julia; Gogishvili, Dea et al.

Part of Communications Medicine, 2026

Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients

Enblad, Anna Pia; Krali, Olga; Gezelius, Henrik; Lundmark, Anders et al.

Part of HemaSphere, 2025

Fluctuating DNA methylation tracks cancer evolution at clinical scale

Gabbutt, Calum; Duran-Ferrer, Martí; Grant, Heather E.; Mallo, Diego et al.

Part of Nature, p. 764-773, 2025

The potential role of environmentally associated DNA methylation in childhood acute lymphoblastic leukaemia subtypes

Saville, Jessica R.; Russell, Lisa J.; Padget, Kay; Ghantous, Akram et al.

Part of International Journal of Cancer, p. 1600-1612, 2025

Genomic determinants of therapy response in ETV6::RUNX1 leukemia

Oksa, Laura; Moisio, Sanni; Maqbool, Khurram; Kramer, Roger et al.

Part of Leukemia, p. 2125-2139, 2025

A human pan-disease blood atlas of the circulating proteome

Álvez, María Bueno; Bergström, Sofia; Kenrick, Josefin; Johansson, Emil et al.

Part of Science, 2025

DOI for A human pan-disease blood atlas of the circulating proteome

Epigenomic diagnosis and prognosis of Acute Myeloid Leukemia

Marchi, Francisco; Shastri, Vivek M.; Marrero, Richard J.; Nguyen, Nam H. K. et al.

Part of Nature Communications, 2025

Error Reduction in Leukemia Machine Learning Classification With Conformal Prediction

Lysenkova, Mariya; Zachariah, Dave; Krali, Olga; Nordlund, Jessica

Part of JCO Clinical Cancer Informatics, 2025

Exploring a pico-well based scRNA-seq method (HIVE) for simplified processing of equine bronchoalveolar lavage cells

Fegraeus, Kim; Riihimäki, Miia; Nordlund, Jessica; Akula, Srinivas et al.

Part of PLOS ONE, 2025

Comparison of high-throughput single-cell RNA-seq methods for ex vivo drug screening

Gezelius, Henrik; Enblad, Anna Pia; Lundmark, Anders; Åberg, Martin et al.

Part of NAR Genomics and Bioinformatics, 2024

Refining risk prediction in pediatric acute lymphoblastic leukemia through DNA methylation profiling

Orgueira, Adrian Mosquera; Krali, Olga; Miguez, Carlos Perez; Raindo, Andres Peleteiro et al.

Part of Clinical Epigenetics, 2024

Multi-modal single cell sequencing of B cells in primary Sjögren's Syndrome.

Arvidsson, Gustav; Czarnewski, Paulo; Johansson, Alina; Raine, Amanda et al.

Part of Arthritis & Rheumatology, p. 255-267, 2024

Pushing the boundaries of rare disease diagnostics with the help of the first Undiagnosed Hackathon

Delgado-Vega, Angelica Maria; Höijer, Ida; Corcoran, Pádraic; Lysenkova, Mariya et al.

Part of Nature Genetics, p. 2287-2294, 2024

DOI for Pushing the boundaries of rare disease diagnostics with the help of the first Undiagnosed Hackathon

Epigenome-wide analysis across the development span of pediatric acute lymphoblastic leukemia: backtracking to birth

Ghantous, Akram; Nussle, Semira Gonseth; Nassar, Farah J.; Spitz, Natalia et al.

Part of Molecular Cancer, 2024

A multiomic characterization of the leukemia cell line REH using short- and long-read sequencing

Lysenkova, Mariya; Arvidsson, Gustav; Bunikis, Ignas; Lundmark, Anders et al.

Part of Life Science Alliance, 2024

BCP neoplasms: same or different?

Nordlund, Jessica

Part of Blood, p. 4-6, 2024

DOI for BCP neoplasms: same or different?

Next generation pan-cancer blood proteome profiling using proximity extension assay

Alvez, Maria Bueno; Edfors, Fredrik; von Feilitzen, Kalle; Zwahlen, Martin et al.

Part of Nature Communications, 2023

Multimodal classification of molecular subtypes in pediatric acute lymphoblastic leukemia

Krali, Olga; Marincevic-Zuniga, Yanara; Arvidsson, Gustav; Enblad, Anna Pia et al.

Part of npj Precision Oncology, 2023

Feasibility to use whole-genome sequencing as a sole diagnostic method to detect genomic aberrations in pediatric B-cell acute lymphoblastic leukemia

Rezayee, Fatemah; Eisfeldt, Jesper; Skaftason, Aron; Ofverholm, Ingegerd et al.

Part of Frontiers in Oncology, 2023

Increased MYB alternative promoter usage is associated with relapse in acute lymphoblastic leukemia

Fehr, André; Arvidsson, Gustav; Nordlund, Jessica; Lönnerholm, Gudmar et al.

Part of Genes, Chromosomes and Cancer, p. 597-606, 2023

Quartet DNA reference materials and datasets for comprehensively evaluating germline variant calling performance

Ren, Luyao; Duan, Xiaoke; Dong, Lianhua; Zhang, Rui et al.

Part of Genome Biology, 2023

Long-read whole-genome analysis of human single cells

Hård, Joanna; Mold, Jeff E; Eisfeldt, Jesper; Tellgren-Roth, Christian et al.

Part of Nature Communications, 2023

Genomic, transcriptomic and epigenomic sequencing data of the B-cell leukemia cell line REH

Lysenkova Wiklander, Mariya; Övernäs, Elin; Lagensjö, Johanna; Raine, Amanda et al.

Part of BMC Research Notes, 2023

Single-cell transcriptomics delineates the immune cell landscape in equine lower airways and reveals upregulation of FKBP5 in horses with asthma.

Riihimäki, Miia; Fegraeus, K. Jaderkvist; Nordlund, Jessica; Waern, Ida et al.

Part of Scientific Reports, p. 16261, 2023

Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative

Butler-Laporte, Guillaume; Povysil, Gundula; Kosmicki, Jack A; Cirulli, Elizabeth T et al.

Part of PLOS Genetics, 2022

Transcriptome sequencing of archived lymphoma specimens is feasible and clinically relevant using exome capture technology

Skaftason, Aron; Qu, Ying; Abdulla, Maysaa; Nordlund, Jessica et al.

Part of Genes, Chromosomes and Cancer, p. 27-36, 2022

Next Generation Plasma Proteomics Identifies High-Precision Biomarker Candidates for Ovarian Cancer.

Gyllensten, Ulf B.; Hedlund-Lindberg, Julia; Svensson, Johanna; Manninen, Johanna et al.

Part of Cancers, 2022

scSPLAT, a scalable plate-based protocol for single cell WGBS library preparation

Raine, Amanda; Lundmark, Anders; Annett, Alva; Wiman, Ann-Christin et al.

Part of Scientific Reports, 2022

A Study Protocol for Validation and Implementation of Whole-Genome and -Transcriptome Sequencing as a Comprehensive Precision Diagnostic Test in Acute Leukemias

Berglund, Eva Caroline; Barbany, Gisela; Orsmark-Pietras, Christina; Fogelstrand, Linda et al.

Part of Frontiers in Medicine, 2022

Tackling the translational challenges of multi-omics research in the realm of European personalised medicine: A workshop report

Oldoni, Emanuela; Saunders, Gary; Bietrix, Florence; Garcia Bermejo, Maria Laura et al.

Part of Frontiers in Molecular Biosciences, 2022

Whole genome and exome sequencing reference datasets from a multi-center and cross-platform benchmark study

Zhao, Yongmei; Fang, Li Tai; Shen, Tsai-wei; Choudhari, Sulbha et al.

Part of Scientific Data, 2021

Expression of BCL6 in paediatric B-cell acute lymphoblastic leukaemia and association with prognosis

Mäkinen, Artturi; Nikkilä, Atte; Mehtonen, Juha; Teppo, Susanna et al.

Part of Pathology, p. 875-882, 2021

Leukocytes with chromosome Y loss have reduced abundance of the cell surface immunoprotein CD99

Mattisson, Jonas; Danielsson, Marcus; Hammond, Maria; Davies, Hanna et al.

Part of Scientific Reports, 2021

DNA Methylation Signatures Predict Cytogenetic Subtype and Outcome in Pediatric Acute Myeloid Leukemia (AML)

Krali, Olga; Palle, J; Bäcklin, Christofer; Abrahamsson, Jonas et al.

Part of Genes, 2021

Immune cells lacking Y chromosome show dysregulation of autosomal gene expression

Dumanski, Jan P.; Halvardson, Jonatan; Davies, Hanna; Rychlicka-Buniowska, Edyta et al.

Part of Cellular and Molecular Life Sciences (CMLS), p. 4019-4033, 2021

Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing

Xiao, Wenming; Ren, Luyao; Chen, Zhong; Fang, Li Tai et al.

Part of Nature Biotechnology, p. 1141-1150, 2021

DOI for Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing

The SEQC2 epigenomics quality control (EpiQC) study

Foox, Jonathan; Nordlund, Jessica; Lalancette, Claudia; Gong, Ting et al.

Part of Genome Biology, 2021

RAG1 co-expression signature identifies ETV6-RUNX1-like B-cell precursor acute lymphoblastic leukemia in children

Chen, Dongfeng; Camponeschi, Alessandro; Nordlund, Jessica; Marincevic-Zuniga, Yanara et al.

Part of Cancer Medicine, p. 3997-4003, 2021

Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing

Fang, Li Tai; Zhu, Bin; Zhao, Yongmei; Chen, Wanqiu et al.

Part of Nature Biotechnology, p. 1151-1160, 2021

DOI for Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing

Mutational patterns and clonal evolution from diagnosis to relapse in pediatric acute lymphoblastic leukemia

Sayyab, Shumaila; Lundmark, Anders; Larsson, Malin; Ringner, Markus et al.

Part of Scientific Reports, 2021

The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome

Duran-Ferrer, Marti; Clot, Guillem; Nadeu, Ferran; Beekman, Renee et al.

Part of Nature Cancer, p. 1066-1081, 2020

DOI for The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome

Refined detection and phasing of structural aberrations in pediatric acute lymphoblastic leukemia by linked-read whole-genome sequencing

Nordlund, Jessica; Marincevic-Zuniga, Yanara; Cavelier, Lucia; Raine, Amanda et al.

Part of Scientific Reports, 2020

Genome assembly of the basket willow, Salix viminalis, reveals earliest stages of sex chromosome expansion

Almeida, Pedro; Proux-Wera, Estelle; Churcher, Allison; Soler, Lucile et al.

Part of BMC Biology, 2020

Overexpression of chromatin remodeling and tyrosine kinase genes in iAMP21-positive acute lymphoblastic leukemia

Ivanov Öfverholm, I.; Zachariadis, V.; Taylan, F.; Marincevic-Zuniga, Yanara et al.

Part of Leukemia and Lymphoma, p. 604-613, 2020

Clinicopathological features and prognostic value of SOX11 in childhood acute lymphoblastic leukemia

Gronroos, Toni; Makinen, Artturi; Laukkanen, Saara; Mehtonen, Juha et al.

Part of Scientific Reports, 2020

Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL

Watanabe, A.; Miyake, K.; Nordlund, Jessica; Syvänen, Ann-Christine et al.

Part of Blood, p. 2319-2333, 2020

DOI for Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL

Transcriptome and Proteome Profiling of Neural Induced Pluripotent Stem Cells from Individuals with Down Syndrome Disclose Dynamic Dysregulations of Key Pathways and Cellular Functions

Sobol, Maria; Klar, Joakim; Laan, Loora; Shahsavani, Mansoureh et al.

Part of Molecular Neurobiology, p. 7113-7127, 2019

CD99 expression is strongly associated with clinical outcome in children with B-cell precursor acute lymphoblastic leukaemia

Chen, Dongfeng; Camponeschi, Alessandro; Wu, Qingqing; Gerasimcik, Natalija et al.

Part of British Journal of Haematology, p. 418-423, 2019

DOI for CD99 expression is strongly associated with clinical outcome in children with B-cell precursor acute lymphoblastic leukaemia

De Novo Assembly of Two Swedish Genomes Reveals Missing Segments from the Human GRCh38 Reference and Improves Variant Calling of Population-Scale Sequencing Data

Ameur, Adam; Che, Huiwen; Martin, Marcel; Bunikis, Ignas et al.

Part of Genes, 2018

Data quality of whole genome bisulfite sequencing on Illumina platforms

Raine, Amanda; Liljedahl, Ulrika; Nordlund, Jessica

Part of PLOS ONE, 2018

DNA methylation holds prognostic information in relapsed precursor B-cell acute lymphoblastic leukemia

Borssen, Magnus; Nordlund, Jessica; Haider, Zahra; Landfors, Mattias et al.

Part of Clinical Epigenetics, 2018

DNA methylation profiling of pediatric B-cell lymphoblastic leukemia with KMT2A rearrangement identifies hypomethylation at enhancer sites

Bergmann, Anke K.; Castellano, Giancarlo; Alten, Julia; Ammerpohl, Ole et al.

Part of Pediatric Blood & Cancer, 2017

DOI for DNA methylation profiling of pediatric B-cell lymphoblastic leukemia with KMT2A rearrangement identifies hypomethylation at enhancer sites

CD27 expression and its association with clinical outcome in children and adults with pro-B acute lymphoblastic leukemia

Chen, D.; Gerasimcik, N.; Camponeschi, A.; Tan, Y. et al.

Part of Blood Cancer Journal, 2017

Transcriptome sequencing in pediatric acute lymphoblastic leukemia identifies fusion genes associated with distinct DNA methylation profiles

Marincevic-Zuniga, Yanara; Dahlberg, Johan; Nilsson, Sara; Raine, Amanda et al.

Part of Journal of Hematology & Oncology, 2017

SPlinted Ligation Adapter Tagging (SPLAT), a novel library preparation method for whole genome bisulphite sequencing

Raine, Amanda; Manlig, Erika; Wahlberg, Per; Syvänen, Ann-Christine et al.

Part of Nucleic Acids Research, 2017

Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes

Imgenberg-Kreuz, Juliana; Sandling, Johanna K.; Almlöf, Jonas Carlsson; Nordlund, Jessica et al.

Part of Annals of the Rheumatic Diseases, p. 2029-2036, 2016

DNA methylome analysis of acute lymphoblastic leukemia cells reveals stochastic de novo DNA methylation in CpG islands

Wahlberg, Per; Lundmark, Anders; Nordlund, Jessica; Busche, Stephan et al.

Part of Epigenomics, p. 1367-1387, 2016

Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes

Lindqvist, C. Mårten; Lundmark, Anders; Nordlund, Jessica; Freyhult, Eva et al.

Part of Oncotarget, p. 64071-64088, 2016

DOI for Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes

PAX5-ESRRB is a recurrent fusion gene in B-cell precursor pediatric acute lymphoblastic leukemia

Marincevic-Zuniga, Yanara; Zachariadis, Vasilios; Cavelier, Lucia; Castor, Anders et al.

Part of Haematologica, 2016

DOI for PAX5-ESRRB is a recurrent fusion gene in B-cell precursor pediatric acute lymphoblastic leukemia

CopyNumber450kCancer: baseline correction for accurate copy number calling from the 450k methylation array

Marzouka, Nour-al-dain; Nordlund, Jessica; Bäcklin, Christofer L.; Lönnerholm, Gudmar et al.

Part of Bioinformatics, p. 1080-1082, 2016

Hypomethylation in Enhancer and Promoter Regions of Interferon Regulated Genes in Multiple Tissues Is Associated with Primary Sjogren's Syndrome

Imgenberg-Kreuz, Juliana; Sandling, Johanna K.; Almlöf, Jonas Carlsson; Nordlund, Jessica et al.

Part of Arthritis & Rheumatology, 2015

DOI for Hypomethylation in Enhancer and Promoter Regions of Interferon Regulated Genes in Multiple Tissues Is Associated with Primary Sjogren's Syndrome

The Mutational Landscape in Pediatric Acute Lymphoblastic Leukemia Deciphered by Whole Genome Sequencing

Lindqvist, C Mårten; Nordlund, Jessica; Ekman, Diana; Johansson, Anna et al.

Part of Human Mutation, p. 118-128, 2015

DOI for The Mutational Landscape in Pediatric Acute Lymphoblastic Leukemia Deciphered by Whole Genome Sequencing

The clinical impact of IKZF1 deletions in paediatric B-cell precursor acute lymphoblastic leukaemia is independent of minimal residual disease stratification in Nordic Society for Paediatric Haematology and Oncology treatment protocols used between 1992 and 2013

Olsson, Linda; Oefverholm, Ingegerd Ivanov; Noren-Nystroem, Ulrika; Zachariadis, Vasilios et al.

Part of British Journal of Haematology, p. 847-858, 2015

DOI for The clinical impact of IKZF1 deletions in paediatric B-cell precursor acute lymphoblastic leukaemia is independent of minimal residual disease stratification in Nordic Society for Paediatric Haematology and Oncology treatment protocols used between 1992 and 2013

DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia

Nordlund, Jessica; Bäcklin, Christofer; Zachariadis, Vasilios; Cavelier, Lucia et al.

Part of Clinical Epigenetics, 2015

Genome-Wide DNA Methylation Analysis of CD19+B Cells in Primary Sjogren's Syndrome

Nordmark, Gunnel; Imgenberg-Kreuz, Juliana; Almlöf, Jonas Carlsson; Nordlund, Jessica et al.

Part of Arthritis & Rheumatology, 2014

Bioinformatic description of immunotherapy targets for pediatric T-cell leukemia and the impact of normal gene sets used for comparison

Orentas, Rimas J; Nordlund, Jessica; He, Jianbin; Sindiri, Sivasish et al.

Part of Frontiers in Oncology, 2014

DOI for Bioinformatic description of immunotherapy targets for pediatric T-cell leukemia and the impact of normal gene sets used for comparison

Prognostic Impact of IKZF1 Deletions in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia Treated According to Nopho Protocols - the Swedish Experience

Ofverholm, I. Ivanov; Olsson, L.; Noren-Nystrom, U.; Forestier, E. et al.

Part of Haematologica, p. 9-9, 2014

Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia

Nordlund, Jessica; Bäcklin, Christofer L; Wahlberg, Per; Busche, Stephan et al.

Part of Genome Biology, 2013

DOI for Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia

Accurate detection of subclonal single nucleotide variants in whole genome amplified and pooled cancer samples using HaloPlex target enrichment

Berglund, Eva C; Lindqvist, Carl Mårten; Hayat, Shahina; Overnäs, Elin et al.

Part of BMC Genomics, p. 856, 2013

DOI for Accurate detection of subclonal single nucleotide variants in whole genome amplified and pooled cancer samples using HaloPlex target enrichment

DNA Methylation Analysis of Bone Marrow Cells at Diagnosis of Acute Lymphoblastic Leukemia and at Remission

Nordlund, Jessica; Milani, Lili; Lundmark, Anders; Lönnerholm, Gudmar et al.

Part of PLOS ONE, 2012

The DNA Methylation Landscape of Paediatric Acute Lymphoblastic Leukemia

Nordlund, Jessica; Backlin, Carin; Wahlberg, Per; Forestier, E. et al.

Part of European Journal of Cancer, 2012

DOI for The DNA Methylation Landscape of Paediatric Acute Lymphoblastic Leukemia

Digital gene expression profiling of primary acute lymphoblastic leukemia cells

Nordlund, Jessica; Kiialainen, Anna; Karlberg, Olof; Berglund, Eva C et al.

Part of Leukemia, p. 1218-1227, 2012

DOI for Digital gene expression profiling of primary acute lymphoblastic leukemia cells

DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia

Milani, Lili; Lundmark, Anders; Kiialainen, Anna; Nordlund, Jessica et al.

Part of Blood, p. 1214-1225, 2010

DOI for DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia

Allele-specific gene expression patterns in primary leukemic cells reveal regulation of gene expression by CpG site methylation

Milani, Lili; Lundmark, Anders; Nordlund, Jessica; Kiialainen, Anna et al.

Part of Genome Research, p. 1-11, 2009

DOI for Allele-specific gene expression patterns in primary leukemic cells reveal regulation of gene expression by CpG site methylation

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