Di Yu

Evaluation of drug delivery vehicles for improved transduction of oncolytic adenoviruses in solid tumor tissue

Yngve, Erik; Ingvast, Sofie; Korsgren, Olle; Yu, Di

Part of Upsala Journal of Medical Sciences, 2025

DOI for Evaluation of drug delivery vehicles for improved transduction of oncolytic adenoviruses in solid tumor tissue
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VLDLR mediates Semliki Forest virus neuroinvasion through the blood-cerebrospinal fluid barrier

Martikainen, Miika; Lugano, Roberta; Pietilä, Ilkka; Brosch, Sofie et al.

Part of Nature Communications, 2024

Targeting ZC3H11A elicits immunogenic cancer cell death through augmentation of antigen presentation and interferon response

Ali, Arwa; Contreras, Paola; Darweesh, Mahmoud; Andersson, Leif et al.

Part of Molecular Therapy Nucleic Acids, 2024

Enhanced Cellular Uptake through Nanotopography-Induced Macropinocytosis

Aramesh, Morteza; Yu, Di; Essand, Magnus; Persson, Cecilia

Part of Advanced Functional Materials, 2024

Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma

Ramachandran, Mohanraj; Vaccaro, Alessandra; van de Walle, Tiarne; Georganaki, Maria et al.

Part of Cancer Cell, p. 1134-1151, 2023

Proinflammatory allogeneic dendritic cells enhance the therapeutic efficacy of systemic anti-4-1BB treatment

Ali, Arwa; Gao, Menghan; Iskantar, Alexandros; Wang, Hai et al.

Part of Frontiers in Immunology, 2023

CD4⁺ T cell-induced inflammatory cell death controls immune-evasive tumours

Kruse, Bastian; Buzzai, Anthony C.; Shridhar, Naveen; Braun, Andreas D. et al.

Part of Nature, p. 1033-1040, 2023

Complementarity-determining region clustering may cause CAR-T cell dysfunction

Sarén, Tina; Saronio, Giulia; Marti Torrell, Paula; Zhu, Xu et al.

Part of Nature Communications, 2023

A qPCR-Based Method for Quantification of RCA Contaminants in Oncolytic Adenovirus Products

Gao, Menghan; Yngve, Erik; Yu, Di; Jin, Chuan

Part of Frontiers in Molecular Biosciences, 2022

Intratumoral administration of pro-inflammatory allogeneic dendritic cells improved the anti-turnor response of systemic anti-CTLA-4 treatment via unleashing a T cell-dependent response

Jin, Chuan; Ali, Arwa; Iskantar, Alexandros; Fotaki, Grammatiki et al.

Part of Oncoimmunology, 2022

Anemoside B4 inhibits enterovirus 71 propagation in mice through upregulating 14-3-3 expression and type I interferon responses

Kang, Nai-xin; Zou, Yue; Liang, Qing-hua; Wang, Yan-er et al.

Part of Acta Pharmacologica Sinica, p. 977-991, 2022

DOI for Anemoside B4 inhibits enterovirus 71 propagation in mice through upregulating 14-3-3 expression and type I interferon responses

CAR T cells expressing a bacterial virulence factor trigger potent bystander antitumour responses in solid cancers

Jin, Chuan; Ma, Jing; Ramachandran, Mohanraj; Yu, Di et al.

Part of Nature Biomedical Engineering, p. 830-841, 2022

Concurrent expression of HP-NAP enhances antitumor efficacy of oncolytic vaccinia virus but not for Semliki Forest virus

Ma, Jing; Jin, Chuan; Čančer, Matko; Wang, Hai et al.

Part of MOLECULAR THERAPY-ONCOLYTICS, p. 356-366, 2021

IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma

Martikainen, Miika; Ramachandran, Mohanraj; Lugano, Roberta; Ma, Jing et al.

Part of MOLECULAR THERAPY-ONCOLYTICS, p. 37-46, 2021

Separable Microneedle Patch to Protect and Deliver DNA Nanovaccines Against COVID-19

Yin, Yue; Su, Wen; Zhang, Jie; Huang, Wenping et al.

Part of ACS Nano, p. 14347-14359, 2021

DOI for Separable Microneedle Patch to Protect and Deliver DNA Nanovaccines Against COVID-19

In Situ Transforming RNA Nanovaccines from Polyethylenimine Functionalized Graphene Oxide Hydrogel for Durable Cancer Immunotherapy

Yin, Yue; Li, Xiaoyang; Ma, Haixia; Zhang, Jie et al.

Part of Nano Letters, p. 2224-2231, 2021

DOI for In Situ Transforming RNA Nanovaccines from Polyethylenimine Functionalized Graphene Oxide Hydrogel for Durable Cancer Immunotherapy

Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer

Ma, Jing; Ramachandran, Mohanraj; Jin, Chuan; Quijano-Rubio, Clara et al.

Part of Cell Death and Disease, 2020

Antischistosomal Properties of Hederacolchiside A1 Isolated from Pulsatilla chinensis

Kang, Naixin; Shen, Wenhua; Gao, Hongwei; Feng, Yulin et al.

Part of Molecules, 2018

CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis

Lugano, Roberta; Vemuri, Kalyani; Yu, Di; Bergqvist, Michael et al.

Part of Journal of Clinical Investigation, p. 3280-3297, 2018

Pro-inflammatory allogeneic DCs promote activation of bystander immune cells and thereby license antigen-specific T-cell responses

Fotaki, Grammatiki; Jin, Chuan; Ramachandran, Mohanraj; Kerzeli, Iliana Kyriaki et al.

Part of Oncoimmunology, 2018

DOI for Pro-inflammatory allogeneic DCs promote activation of bystander immune cells and thereby license antigen-specific T-cell responses

Cancer vaccine based on a combination of an infection-enhanced adenoviral vector and pro-inflammatory allogeneic DCs leads to sustained antigen-specific immune responses in three melanoma models

Fotaki, Grammatiki; Jin, Chuan; Kerzeli, Iliana Kyriaki; Ramachandran, Mohanraj et al.

Part of Oncoimmunology, 2018

Modifying melanoma immune microenvironment by heterologous prime-boost vaccination with adenovirus and Modified Vaccinia Ankara virus vectors

Shridhar, N.; Ruotsalainen, J.; van der Sluis, T.; Rogava, M. et al.

Part of Experimental dermatology, 2018

Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth

Younis, Shady; Kamel, Wael; Falkeborn, Tina; Wang, Hao et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2018

DOI for Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth

Safe and effective treatment of experimental neuroblastoma and glioblastoma using systemically administered triple microRNA-detargeted oncolytic Semliki Forest virus

Ramachandran, Mohanraj; Yu, Di; Dyczynski, Matheus; Baskaran, Sathishkumar et al.

Part of Clinical Cancer Research, p. 1519-1530, 2017

DOI for Safe and effective treatment of experimental neuroblastoma and glioblastoma using systemically administered triple microRNA-detargeted oncolytic Semliki Forest virus

Preclinical Evaluation of AdVince, an Oncolytic Adenovirus Adapted for Treatment of Liver Metastases from Neuroendocrine Cancer

Yu, Di; Leja, Justyna; Loskog, Angelica S.; Hellman, Per et al.

Part of Neuroendocrinology, p. 54-66, 2017

DOI for Preclinical Evaluation of AdVince, an Oncolytic Adenovirus Adapted for Treatment of Liver Metastases from Neuroendocrine Cancer

Inhibition of Heparanase in Pediatric Brain Tumor Cells Attenuates their Proliferation, Invasive Capacity, and In Vivo Tumor Growth

Spyrou, Argyris; Kundu, Soumi; Haseeb, Lulu; Yu, Di et al.

Part of Molecular Cancer Therapeutics, p. 1705-1716, 2017

DOI for Inhibition of Heparanase in Pediatric Brain Tumor Cells Attenuates their Proliferation, Invasive Capacity, and In Vivo Tumor Growth

Adenovirus, Semliki Forest virus and vaccinia virus-induced immunogenic cell death augments oncolytic virus immunotherapy

Ma, Jing; Ramachandran, Mohanraj; Jin, Chuan; Essand, Magnus et al.

Part of Scandinavian Journal of Immunology, p. 341-341, 2017

Insertion of the Type-I IFN Decoy Receptor B18R in a miRNA-Tagged Semliki Forest Virus Improves Oncolytic Capacity but Results in Neurotoxicity

Sarén, Tina; Ramachandran, Mohanraj; Martikainen, Miika; Yu, Di

Part of MOLECULAR THERAPY-ONCOLYTICS, p. 67-75, 2017

CAR T-Cells with Induced Secretion of Helicobacter Pylori Neutrophil-Activating Protein (HP-NAP) Yields Improved Anti-Tumor Activity and Reduced Immunosuppression

Essand, Magnus; Ma, Jing; Jin, Chuan; Ramachandran, Mohanraj et al.

Part of Molecular Therapy, p. 288-288, 2017

HAdV-2-suppressed growth of SV40 T antigen-transformed mouse mammary epithelial cell-induced tumours in SCID mice

Wu, Chengjun; Cao, Xiaofang; Yu, Di; Huijbers, Elisabeth J. M. et al.

Part of Virology, p. 44-50, 2016

DOI for HAdV-2-suppressed growth of SV40 T antigen-transformed mouse mammary epithelial cell-induced tumours in SCID mice

A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients

Lind, Anne-Li; Yu, Di; Freyhult, Eva; Bodolea, Constantin et al.

Part of PLOS ONE, 2016

Prospects to improve chimeric antigen receptor T-cell therapy for solid tumors

Jin, Chuan; Yu, Di; Essand, Magnus

Part of Immunotherapy, p. 1355-1361, 2016

DOI for Prospects to improve chimeric antigen receptor T-cell therapy for solid tumors

Allogeneic dendritic cells (AlloDCs) transduced with an infection enhanced adenovirus as adjuvant for cancer immunotherapy

Fotaki, Grammatiki; Jin, Chuan; Karlsson-Parra, Alex; Yu, Di et al.

Part of CANCER IMMUNOLOGY RESEARCH, 2016

DOI for Allogeneic dendritic cells (AlloDCs) transduced with an infection enhanced adenovirus as adjuvant for cancer immunotherapy

Long-term episomal gene transfer for safe engineering of T cells for adoptive cell therapy of cancer

Jin, Chuan; Ramachandran, Mohanraj; Fotaki, Grammatiki; Nilsson, Berith et al.

Part of CANCER IMMUNOLOGY RESEARCH, 2016

DOI for Long-term episomal gene transfer for safe engineering of T cells for adoptive cell therapy of cancer

Safe engineering of CAR T cells for adoptive cell therapy of cancer using long-term episomal gene transfer

Jin, Chuan; Fotaki, Grammatiki; Ramachandran, Mohanraj; Nilsson, Berith et al.

Part of EMBO Molecular Medicine, p. 702-711, 2016

Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Zhang, Lei; Kundu, Soumi; Feenstra, Tjerk; Li, Xiujuan et al.

Part of Science Signaling, 2015

DOI for Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Chondroitin Sulfate-Coated DNA-Nanoplexes Enhance Transfection Efficiency by Controlling Plasmid Release from Endosomes: A New Insight into Modulating Nonviral Gene Transfection

Yan, Hongji; Podiyan, Oommen; Yu, Di; Hilborn, Jöns et al.

Part of Advanced Functional Materials, p. 3907-3915, 2015

DOI for Chondroitin Sulfate-Coated DNA-Nanoplexes Enhance Transfection Efficiency by Controlling Plasmid Release from Endosomes: A New Insight into Modulating Nonviral Gene Transfection

Long-term episomal gene transfer for safe engineering of T-cells for adoptive cell therapy of cancer

Jin, Chuan; Ramachandran, Mohanraj; Fotaki, Grammatiki; Nilsson, Bo et al.

Part of Human Gene Therapy, 2014

A Hexon and Fiber-modified Adenovirus Expressing CD40L Improves the Antigen Presentation Capacity of Dendritic Cells

Liljenfeldt, Lina; Yu, Di; Chen, Liye; Essand, Magnus et al.

Part of Journal of immunotherapy (1997), p. 155-162, 2014

DOI for A Hexon and Fiber-modified Adenovirus Expressing CD40L Improves the Antigen Presentation Capacity of Dendritic Cells

Adenovirus Encoded Helicobacter pylori Neutrophil Activating Protein Promotes Maturation of DCs with Th-1 Polarization, Improved Antigen Presentation and Migration

Ramachandran, Mohanraj; Jin, Chuan; Yu, Di; Eriksson, Fredrik et al.

Part of Molecular Therapy, 2014

Vector-Encoded Helicobacter pylori Neutrophil-Activating Protein Promotes Maturation of Dendritic Cells with Th1 Polarization and Improved Migration

Ramachandran, Mohanraj; Jin, Chuan; Yu, Di; Eriksson, Fredrik et al.

Part of Journal of Immunology, p. 2287-2296, 2014

DOI for Vector-Encoded Helicobacter pylori Neutrophil-Activating Protein Promotes Maturation of Dendritic Cells with Th1 Polarization and Improved Migration

Allogeneic lymphocyte-licensed DCs expand T cells withimproved antitumor activity and resistance to oxidative stress andimmunosuppressive factors

Jin, Chuan; Yu, Di; Hillerdal, Victoria; Wallgren, AnnaCarin et al.

Part of Molecular Therapy Methods & Clinical Development, 2014

DOI for Allogeneic lymphocyte-licensed DCs expand T cells withimproved antitumor activity and resistance to oxidative stress andimmunosuppressive factors

Allogeneic Lymphocyte-Licensed DCs Expand TCR/CAR-Engineered T Cells, Which Are Insensitive To Oxidative Stress and Immunosuppressive Factors

Jin, Chuan; Yu, Di; Karlsson-Parra, Alex; Essand, Magnus

Part of Molecular Therapy, 2014

An infection-enhanced oncolytic adenovirus secreting H. pylori neutrophil-activating protein with therapeutic effects on neuroendocrine tumors

Ramachandran, Mohanraj; Yu, Di; Wanders, Alkwin; Essand, Magnus et al.

Part of Molecular Therapy, p. 2008-2018, 2013

Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures

Yu, Di; Jin, Chuan; Ramachandran, Mohanraj; Xu, Jing et al.

Part of PLOS ONE, 2013

Tat‐PTD‐modified Oncolytic Adenovirus Driven by the SCG3 Promoter and ASH1 Enhancer for Neuroblastoma Therapy

Jin, Chuan; Yu, Di; Čančer, Matko; Nilsson, Berith et al.

Part of Human Gene Therapy, p. 766-775, 2013

Oncolytic adenovirus modified with somatostatin motifs for selective infection of neuroendocrine tumor cells

Leja, Justyna; Yu, Di; Nilsson, Berith; Gedda, Lars et al.

Part of Gene Therapy, p. 1052-1062, 2011

DOI for Oncolytic adenovirus modified with somatostatin motifs for selective infection of neuroendocrine tumor cells

Adenovirus with Hexon Tat-Protein Transduction Domain Modification Exhibits Increased Therapeutic Effect in Experimental Neuroblastoma and Neuroendocrine Tumors

Yu, Di; Jin, Chuan; Leja, Justyna; Majdalani, Nadim et al.

Part of Journal of Virology, p. 13114-13123, 2011

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