Eldar Abdurakhmanov

Amino acid substitutions in human growth hormone affect secondary structure and receptor binding

Rajkovic, Andrei; Kanchugal, Sandesh; Abdurakhmanov, Eldar; Howard, Rebecca et al.

Part of PLOS ONE, 2023

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Sequence specificity in DNA binding is mainly governed by association

Marklund, Emil; Mao, Guanzhong; Yuan, Jinwen; Zikrin, Spartak et al.

Part of Science, p. 442-445, 2022

• DOI for Sequence specificity in DNA binding is mainly governed by association
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Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ

Al-Amin, Rasel A.; Johansson, Lars; Abdurakhmanov, Eldar; Landegren, Nils et al.

Part of Nucleic Acids Research, 2022

• DOI for Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ
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Sensitive protein detection using site-specifically oligonucleotide-conjugated nanobody reagents

Al-Amin, Rasel Abdullah; Muthelo, Phathutshedzo M.; Abdurakhmanov, Eldar; Vincke, Cecile et al.

Part of Analytical Chemistry, p. 10054-10061, 2022

• DOI for Sensitive protein detection using site-specifically oligonucleotide-conjugated nanobody reagents
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Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses

Luttens, Andreas; Gullberg, Hjalmar; Abdurakhmanov, Eldar; Vo, Duy Duc et al.

Part of Journal of the American Chemical Society, p. 2905-2920, 2022

• DOI for Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses
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Amino acid substitutions in human growth hormone affect secondary structure and receptor binding

Rajkovic, Andrei; Kanchugal, Sandesh; Abdurakhmanov, Eldar; Howard, Rebecca et al.

Part of PLOS ONE, 2023

• DOI for Amino acid substitutions in human growth hormone affect secondary structure and receptor binding
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Sequence specificity in DNA binding is mainly governed by association

Marklund, Emil; Mao, Guanzhong; Yuan, Jinwen; Zikrin, Spartak et al.

Part of Science, p. 442-445, 2022

• DOI for Sequence specificity in DNA binding is mainly governed by association
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Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ

Al-Amin, Rasel A.; Johansson, Lars; Abdurakhmanov, Eldar; Landegren, Nils et al.

Part of Nucleic Acids Research, 2022

• DOI for Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ
• Download full text (pdf) of Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ

Sensitive protein detection using site-specifically oligonucleotide-conjugated nanobody reagents

Al-Amin, Rasel Abdullah; Muthelo, Phathutshedzo M.; Abdurakhmanov, Eldar; Vincke, Cecile et al.

Part of Analytical Chemistry, p. 10054-10061, 2022

• DOI for Sensitive protein detection using site-specifically oligonucleotide-conjugated nanobody reagents
• Download full text (pdf) of Sensitive protein detection using site-specifically oligonucleotide-conjugated nanobody reagents

Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses

Luttens, Andreas; Gullberg, Hjalmar; Abdurakhmanov, Eldar; Vo, Duy Duc et al.

Part of Journal of the American Chemical Society, p. 2905-2920, 2022

• DOI for Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses
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Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

Bonagas, Nadilly; Gustafsson, Nina M. S.; Henriksson, Martin; Marttila, Petra et al.

Part of NATURE CANCER, p. 156, 2022

• DOI for Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress
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Estimating Detection Limits of Potentiometric DNA sensors Using Surface Plasmon Resonance Analyses

Xu, Xingxing; Makaraviciute, Asta; Abdurakhmanov, Eldar; Werneling, Fredrik et al.

Part of ACS Sensors, p. 217-224, 2020

• DOI for Estimating Detection Limits of Potentiometric DNA sensors Using Surface Plasmon Resonance Analyses

Structural Changes of Mercaptohexanol Self-assembled Monolayers on Gold and their Influence on Impedimetric Aptamer Sensors

Xu, Xingxing; Makaraviciute, Asta; Kumar, Shalen; Wen, Chenyu et al.

Part of Analytical Chemistry, p. 14697-14704, 2019

• DOI for Structural Changes of Mercaptohexanol Self-assembled Monolayers on Gold and their Influence on Impedimetric Aptamer Sensors

Pan-NS3 protease inhibitors of hepatitis C virus based on an R3-elongated pyrazinone scaffold

Belfrage, Anna Karin; Abdurakhmanov, Eldar; Åkerblom, Eva; Brandt, Peter et al.

Part of European Journal of Medicinal Chemistry, p. 453-464, 2018

• DOI for Pan-NS3 protease inhibitors of hepatitis C virus based on an R3-elongated pyrazinone scaffold

Biophysical Mode-of-Action and Selectivity Analysis of Allosteric Inhibitors of Hepatitis C Virus (HCV) Polymerase

Abdurakhmanov, Eldar; Solbak, Sara Oie; Danielson, U. Helena

Part of Viruses, 2017

• DOI for Biophysical Mode-of-Action and Selectivity Analysis of Allosteric Inhibitors of Hepatitis C Virus (HCV) Polymerase
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Characterization of interactions between hepatitis C virus NS5B polymerase, annexin A2 and RNA - effects on NS5B catalysis and allosteric inhibition

Solbak, Sara M.Ø.; Abdurakhmanov, Eldar; Vedeler, Anni; Danielson, U. Helena

Part of Virology Journal, 2017

• DOI for Characterization of interactions between hepatitis C virus NS5B polymerase, annexin A2 and RNA - effects on NS5B catalysis and allosteric inhibition
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Discovery of pyrazinone based compounds that potently inhibit the drug resistant enzyme variant R155K of the hepatitis C virus NS3 protease

Belfrage, Anna Karin; Abdurakhmanov, Eldar; Åkerblom, Eva; Brandt, Peter et al.

Part of Bioorganic & Medicinal Chemistry, p. 2603-2620, 2016

• DOI for Discovery of pyrazinone based compounds that potently inhibit the drug resistant enzyme variant R155K of the hepatitis C virus NS3 protease

Resolution of the Interaction Mechanisms and Characteristics of Non-nucleoside Inhibitors of Hepatitis C Virus Polymerase - Laying the Foundation for Discovery of Allosteric HCV Drugs

Winquist, Johan; Abdurakhmanov, Eldar; Baraznenok, Vera; Henderson, Ian et al.

Part of Antiviral Research, p. 356-368, 2013

• DOI for Resolution of the Interaction Mechanisms and Characteristics of Non-nucleoside Inhibitors of Hepatitis C Virus Polymerase - Laying the Foundation for Discovery of Allosteric HCV Drugs

Discovery and evaluation of direct acting antivirals against hepatitis C virus

Abdurakhmanov, Eldar

2015

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Target Engagement-Mediated Amplification for Monitoring Drug-Target Interactions in Situ

Al-Amin, Rasel A.; Johansson, Lars; Landegren, Nils; Löf, Liza et al.