Maria Norlin

Cellular responses to silencing of PDIA3 (protein disulphide-isomerase A3): Effects on proliferation, migration, and genes in control of active vitamin D

Kermpatsou, Despoina; Olsson, Frida; Wåhlén, Erik; Söderberg, Ola et al.

Part of Journal of Steroid Biochemistry and Molecular Biology, 2024

• DOI for Cellular responses to silencing of PDIA3 (protein disulphide-isomerase A3): Effects on proliferation, migration, and genes in control of active vitamin D
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Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation

Olsson, Frida; Wåhlén, Erik; Heldin, Johan; Söderberg, Ola et al.

Part of Biochemical and Biophysical Research Communications - BBRC, 2024

• DOI for Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation
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Enzymatic activation in vitamin D signaling: Past, present and future

Norlin, Maria; Wikvall, Kjell

Part of Archives of Biochemistry and Biophysics, 2023

• DOI for Enzymatic activation in vitamin D signaling: Past, present and future
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Effects of 1a,25-dihydroxyvitamin D-3 and tacalcitol on cell signaling and anchorage-independent growth in T98G and U251 glioblastoma cells

Olsson, Frida; Sarri, Niki; Papadopoulos, Natalia; Lennartsson, Johan et al.

Part of Biochemistry and Biophysics Reports, 2022

• DOI for Effects of 1a,25-dihydroxyvitamin D-3 and tacalcitol on cell signaling and anchorage-independent growth in T98G and U251 glioblastoma cells
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A method for Boolean analysis of protein interactions at a molecular level

Raykova, Doroteya; Kermpatsou, Despoina; Malmqvist, Tony; Harrison, Philip J et al.

Part of Nature Communications, 2022

• DOI for A method for Boolean analysis of protein interactions at a molecular level
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Cellular responses to silencing of PDIA3 (protein disulphide-isomerase A3): Effects on proliferation, migration, and genes in control of active vitamin D

Kermpatsou, Despoina; Olsson, Frida; Wåhlén, Erik; Söderberg, Ola et al.

Part of Journal of Steroid Biochemistry and Molecular Biology, 2024

• DOI for Cellular responses to silencing of PDIA3 (protein disulphide-isomerase A3): Effects on proliferation, migration, and genes in control of active vitamin D
• Download full text (pdf) of Cellular responses to silencing of PDIA3 (protein disulphide-isomerase A3): Effects on proliferation, migration, and genes in control of active vitamin D

Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation

Olsson, Frida; Wåhlén, Erik; Heldin, Johan; Söderberg, Ola et al.

Part of Biochemical and Biophysical Research Communications - BBRC, 2024

• DOI for Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation
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Effects of 1a,25-dihydroxyvitamin D-3 and tacalcitol on cell signaling and anchorage-independent growth in T98G and U251 glioblastoma cells

Olsson, Frida; Sarri, Niki; Papadopoulos, Natalia; Lennartsson, Johan et al.

Part of Biochemistry and Biophysics Reports, 2022

• DOI for Effects of 1a,25-dihydroxyvitamin D-3 and tacalcitol on cell signaling and anchorage-independent growth in T98G and U251 glioblastoma cells
• Download full text (pdf) of Effects of 1a,25-dihydroxyvitamin D-3 and tacalcitol on cell signaling and anchorage-independent growth in T98G and U251 glioblastoma cells

A method for Boolean analysis of protein interactions at a molecular level

Raykova, Doroteya; Kermpatsou, Despoina; Malmqvist, Tony; Harrison, Philip J et al.

Part of Nature Communications, 2022

• DOI for A method for Boolean analysis of protein interactions at a molecular level
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Effects of glucocorticoids on vitamin D₃-metabolizing 24-hydroxylase (CYP24A1) in Saos-2 cells and primary human osteoblasts

Zayny, Ahmad; Almokhtar, Mokhtar; Wikvall, Kjell; Ljunggren, Östen et al.

Part of Molecular and Cellular Endocrinology, 2019

• DOI for Effects of glucocorticoids on vitamin D₃-metabolizing 24-hydroxylase (CYP24A1) in Saos-2 cells and primary human osteoblasts

Vitamin D Analogues Tacalcitol and Calcipotriol Inhibit Proliferation and Migration of T98G Human Glioblastoma Cells

Emanuelsson, Ida; Wikvall, Kjell; Friman, Tomas; Norlin, Maria

Part of Neuroscience, p. 130-136, 2018

• DOI for Vitamin D Analogues Tacalcitol and Calcipotriol Inhibit Proliferation and Migration of T98G Human Glioblastoma Cells

Expression and regulation of CYP17A1 and 3β-hydroxysteroid dehydrogenase in cells of the nervous system: potential effects of vitamin D on brain steroidogenesis

Emanuelsson, Ida; Almokhtar, Mokhtar; Wikvall, Kjell; Gröndbladh, Alfhild et al.

Part of Neurochemistry International, p. 46-55, 2018

• DOI for Expression and regulation of CYP17A1 and 3β-hydroxysteroid dehydrogenase in cells of the nervous system: potential effects of vitamin D on brain steroidogenesis

Drug-mediated gene regulation of vitamin D₃ metabolism in primary human dermal fibroblasts

Norlin, Maria; Lundqvist, Johan; Ellfolk, Maria; Hellström Pigg, Maritta et al.

Part of Basic & Clinical Pharmacology & Toxicology, p. 59-63, 2017

• DOI for Drug-mediated gene regulation of vitamin D₃ metabolism in primary human dermal fibroblasts

Effects of osteoporosis-inducing drugs on vitamin D-related gene transcription and mineralization in MG-63 and Saos-2 cells

Wegler, Christine; Wikvall, Kjell; Norlin, Maria

Part of Basic & Clinical Pharmacology & Toxicology, 2016

• DOI for Effects of osteoporosis-inducing drugs on vitamin D-related gene transcription and mineralization in MG-63 and Saos-2 cells

Motor neuron-like NSC-34 cells as a new model for the study of vitamin D metabolism in the brain.

Almokhtar, Mokhtar; Wikvall, Kjell; Ubhayasekera, S. J. Kumari A.; Bergquist, Jonas et al.

Part of Journal of Steroid Biochemistry and Molecular Biology, p. 178-188, 2016

• DOI for Motor neuron-like NSC-34 cells as a new model for the study of vitamin D metabolism in the brain.

Estrogen-mediated regulation of steroid metabolism in rat glial cells; effects on neurosteroid levels via regulation of CYP7B1-mediated catalysis

Wicher, Grzegorz; Norlin, Maria

Part of Journal of Steroid Biochemistry and Molecular Biology, p. 21-27, 2015

• DOI for Estrogen-mediated regulation of steroid metabolism in rat glial cells; effects on neurosteroid levels via regulation of CYP7B1-mediated catalysis

Vitamin D-mediated regulation of CYP21A2 transcription – a novel mechanism for vitamin D action

Lundqvist, Johan; Wikvall, Kjell; Norlin, Maria

Part of Biochimica et Biophysica Acta - General Subjects, p. 1553-1559, 2012

• DOI for Vitamin D-mediated regulation of CYP21A2 transcription – a novel mechanism for vitamin D action

Effects of CYP7B1-related steroids on androgen receptor activation in different cell lines

Lundqvist, Johan; Norlin, Maria

Part of Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, p. 973-979, 2012

• DOI for Effects of CYP7B1-related steroids on androgen receptor activation in different cell lines

Protective effects of 27-and 24-hydroxycholesterol against staurosporine-induced cell death in undifferentiated neuroblastoma SH-SY5Y cells

Emanuelsson, Ida; Norlin, Maria

Part of Neuroscience Letters, p. 44-48, 2012

• DOI for Protective effects of 27-and 24-hydroxycholesterol against staurosporine-induced cell death in undifferentiated neuroblastoma SH-SY5Y cells

Effects on DHEA levels by estrogen in rat astrocytes and CNS co-cultures via the regulation of CYP7B1-mediated metabolism

Svenningsen, Åsa Fex; Wicher, Grzegorz; Lundqvist, Johan; Pettersson, Hanna et al.

Part of Neurochemistry International, p. 620-624, 2011

• DOI for Effects on DHEA levels by estrogen in rat astrocytes and CNS co-cultures via the regulation of CYP7B1-mediated metabolism

Androgen receptor-mediated regulation of the anti-atherogenic enzyme CYP27A1 involves the JNK/c-jun pathway

Norlin, Maria; Pettersson, Hanna; Tang, Wanjin; Wikvall, Kjell

Part of Archives of Biochemistry and Biophysics, p. 236-241, 2011

• DOI for Androgen receptor-mediated regulation of the anti-atherogenic enzyme CYP27A1 involves the JNK/c-jun pathway

1α,25-Dihydroxyvitamin D₃ exerts tissue-specific effects on estrogen and androgen metabolism

Lundqvist, Johan; Norlin, Maria; Wikvall, Kjell

Part of Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, p. 263-270, 2011

• DOI for 1α,25-Dihydroxyvitamin D₃ exerts tissue-specific effects on estrogen and androgen metabolism

CYP7A1 (cytochrome P450, family 7, subfamily A, polypeptide 1)

Norlin, Maria; Wikvall, Kjell

Part of Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2010

Effects of CYP7B1-mediated catalysis on estrogen receptor activation.

Pettersson, Hanna; Lundqvist, Johan; Norlin, Maria

Part of Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, p. 1090-1097, 2010

• DOI for Effects of CYP7B1-mediated catalysis on estrogen receptor activation.

1α,25-Dihydroxyvitamin D₃ affects hormone production and expression of steroidogenic enzymes in human adrenocortical NCI-H295R cells

Lundqvist, Johan; Norlin, Maria; Wikvall, Kjell

Part of Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, p. 1056-1062, 2010

• DOI for 1α,25-Dihydroxyvitamin D₃ affects hormone production and expression of steroidogenic enzymes in human adrenocortical NCI-H295R cells

CYP7B1 (cytochrome P450, family 7, subfamily B, polypeptide 1)

Norlin, Maria

Part of Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2009

Regulation of human vitamin D(3) 25-hydroxylases in dermal fibroblasts and prostate cancer LNCaP cells

Ellfolk, Maria; Norlin, Maria; Gyllensten, Katarina; Wikvall, Kjell

Part of Molecular Pharmacology, p. 1392-1399, 2009

• DOI for Regulation of human vitamin D(3) 25-hydroxylases in dermal fibroblasts and prostate cancer LNCaP cells

CYP7B1-mediated metabolism of 5 alfa-androstane-3 alfa,17 beta-diol (3 alfa-Adiol): A novel pathway for potential regulation of the cellular levels of androgens and neurosteroids

Pettersson, Hanna; Lundqvist, Johan; Oliw, Ernst; Norlin, Maria

Part of Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, p. 1206-1215, 2009

• DOI for CYP7B1-mediated metabolism of 5 alfa-androstane-3 alfa,17 beta-diol (3 alfa-Adiol): A novel pathway for potential regulation of the cellular levels of androgens and neurosteroids

Glucocorticoid receptor-mediated upregulation of human CYP27A1, a potential anti-atherogenic enzyme

Tang, Wanjin; Norlin, Maria; Wikvall, Kjell

Part of Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, p. 718-723, 2008

• DOI for Glucocorticoid receptor-mediated upregulation of human CYP27A1, a potential anti-atherogenic enzyme

Involvement of the PI3K/Akt pathway in estrogen-mediated regulation of human CYP7B1: identification of CYP7B1 as a novel target for PI3K/Akt and MAPK signalling

Tang, Wanjin; Pettersson, Hanna; Norlin, Maria

Part of Journal of Steroid Biochemistry and Molecular Biology, p. 63-73, 2008

• DOI for Involvement of the PI3K/Akt pathway in estrogen-mediated regulation of human CYP7B1: identification of CYP7B1 as a novel target for PI3K/Akt and MAPK signalling

Metabolism of a novel side chain modified Delta 8(14)-15-ketosterol, a potential cholesterol lowering drug: 28-hydroxylation by CYP27A1

Pettersson, Hanna; Norlin, Maria; Andersson, Ulla; Pikuleva, Irina et al.

Part of Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, p. 383-390, 2008

• DOI for Metabolism of a novel side chain modified Delta 8(14)-15-ketosterol, a potential cholesterol lowering drug: 28-hydroxylation by CYP27A1

CYP7B1-mediated metabolism of dehydroepiandrosterone and 5alpha-androstane-3beta,17beta-diol--potential role(s) for estrogen signaling

Pettersson, Hanna; Holmberg, Lisa; Axelson, Magnus; Norlin, Maria

Part of The FEBS Journal, p. 1778-1789, 2008

• DOI for CYP7B1-mediated metabolism of dehydroepiandrosterone and 5alpha-androstane-3beta,17beta-diol--potential role(s) for estrogen signaling

Phenobarbital suppresses vitamin D3 25-hydroxylase expression: A potential new mechanism for drug-induced osteomalacia

Hosseinpour, Fardin; Ellfolk, Maria; Norlin, Maria; Wikvall, Kjell

Part of Biochemical and Biophysical Research Communications - BBRC, p. 603-607, 2007

• DOI for Phenobarbital suppresses vitamin D3 25-hydroxylase expression: A potential new mechanism for drug-induced osteomalacia

Regulation of human CYP27A1 by estrogens and androgens in HepG2 and prostate cells

Tang, Wanjin; Norlin, Maria; Wikvall, Kjell

Part of Archives of Biochemistry and Biophysics, p. 13-20, 2007

• DOI for Regulation of human CYP27A1 by estrogens and androgens in HepG2 and prostate cells

Isolation and properties of the CYP2D25 promoter: Transcriptional regulation by vitamin D3 metabolites

Ellfolk, Maria; Norlin, Maria; Wikvall, Kjell

Part of Biochemical and Biophysical Research Communications - BBRC, p. 568-572, 2006

• DOI for Isolation and properties of the CYP2D25 promoter: Transcriptional regulation by vitamin D3 metabolites

Estrogen-mediated regulation of CYP7B1: a possible role for controlling DHEA levels in human tissues

Tang, Wanjin; Eggertsen, Gösta; Chiang, John Y.L.; Norlin, Maria

Part of Journal of Steroid Biochemistry and Molecular Biology, p. 42-51, 2006

• DOI for Estrogen-mediated regulation of CYP7B1: a possible role for controlling DHEA levels in human tissues

Regulation of steroid hydroxylase CYP7B1 by androgens and estrogens in prostate cancer LNCaP cells

Tang, Wanjin; Norlin, Maria

Part of Biochemical and Biophysical Research Communications - BBRC, p. 540-546, 2006

• DOI for Regulation of steroid hydroxylase CYP7B1 by androgens and estrogens in prostate cancer LNCaP cells

Regulation of steroid hydroxylase CYP7B1 by androgens and estrogens in prostate cancer LNCaP cells

Tang, Wanjin; Norlin, Maria

Part of Biochemical and Biophysical Research Communications - BBRC, p. 540-546, 2006

• DOI for Regulation of steroid hydroxylase CYP7B1 by androgens and estrogens in prostate cancer LNCaP cells

Flutamide metabolism in four different species in vitro and identification of flutamide metabolites in human patient urine by high performance liquid chromatography/tandem mass spectrometry.

Tevell, Annica; Lennernäs, Hans; Jönsson, Mats; Norlin, Maria et al.

Part of Drug Metab Dispos, p. 984-92, 2006

Transcriptional regulation of human oxysterol 7alpha-hydroxylase by sterol response element binding protein

Norlin, Maria; Chiang, John Y. L.

Part of Biochemical and Biophysical Research Communications - BBRC, p. 158-164, 2004

• DOI for Transcriptional regulation of human oxysterol 7alpha-hydroxylase by sterol response element binding protein

On the substrate specificity of human CYP27A1: implications for bile acid and cholestanol formation

Norlin, Maria; von Bahr, Sara; Björkhem, Ingemar; Wikvall, Kjell

Part of Journal of Lipid Research, p. 1515-1522, 2003

• DOI for On the substrate specificity of human CYP27A1: implications for bile acid and cholestanol formation

Metabolism of 4 beta -hydroxycholesterol in humans

Bodin, Karl; Andersson, Ulla; Rystedt, Eva; Ellis, Eva et al.

Part of Journal of Biological Chemistry, p. 31534-31540, 2002

• DOI for Metabolism of 4 beta -hydroxycholesterol in humans

Enzymatic activation in vitamin D signaling: Past, present and future

Norlin, Maria; Wikvall, Kjell

Part of Archives of Biochemistry and Biophysics, 2023

• DOI for Enzymatic activation in vitamin D signaling: Past, present and future
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Effects of vitamin D in the nervous system: Special focus on interaction with steroid hormone signalling and a possible role in the treatment of brain cancer

Norlin, Maria

Part of Journal of neuroendocrinology, 2020

• DOI for Effects of vitamin D in the nervous system: Special focus on interaction with steroid hormone signalling and a possible role in the treatment of brain cancer

Regulation of cellular steroid levels with special focus on oxysterol and estrogen metabolism

Norlin, Maria

Part of Future Lipidology, p. 337-346, 2008

• DOI for Regulation of cellular steroid levels with special focus on oxysterol and estrogen metabolism

Enzymes in the conversion of cholesterol into bile acids

Norlin, Maria; Wikvall, Kjell

Part of Current molecular medicine, p. 199-218, 2007

• DOI for Enzymes in the conversion of cholesterol into bile acids

Tissue-specific regulation of sex hormone biosynthesis and metabolism: novel aspects on hormonal signalling and maintenance of cellular steroid levels

Norlin, Maria; Wikvall, Kjell

Part of Sex Hormones, INTECH, 2011

Regulation of CYP enzymes in steroidogenesis with particular focus on cholesterol metabolism and vitamin D-related processes

Wikvall, Kjell; Ellfolk, Maria; Tang, Wanjin; Lundqvist, Johan et al.

Part of Proceedings of the 16th International Conference on Cytochrome P450, Nago, Okinawa, Japan, June 21-25, p. 177-182, 2009

Effects of glucocorticoids on vitamin D3 24-hydroxylase (CYP24A1) in Saos-2 cells and primary human osteoblasts

Zayny, Ahmad; Almokhtar, Mokhtar; Wikvall, Kjell; Ljunggren, Östen et al.

Vitamin D metabolism in the nervous system: potential effects of glucocorticoids

Almokhtar, Mokhtar; Wikvall, Kjell; Norlin, Maria