Per-Eric Lund

Functional differences of Munc18 isoforms reflect their affinities for the exocytosis site

Liu, Liangwen; Echeverry, Santiago; Omar-Hmeadi, Muhmmad; Česnokova, Irina et al.

Part of Cellular and Molecular Life Sciences (CMLS), 2026

DOI for Functional differences of Munc18 isoforms reflect their affinities for the exocytosis site
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Dynamic recruitment of Munc13 primes docked secretory granules for exocytosis

Echeverry, Santiago; Saras, Jan; Lund, Per-Eric; Dunevall, Johan et al.

Part of Cell Reports, 2025

RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function

Ibrahim, Hazem; Balboa, Diego; Saarimäki-Vire, Jonna; Montaser, Hossam et al.

Part of Diabetologia, p. 1642-1662, 2024

Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets

Golec, Ewelina; Ekstrom, Alexander; Noga, Maciej; Omar-Hmeadi, Muhmmad et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2022

Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells.

Balboa, Diego; Barsby, Tom; Lithovius, Väinö; Saarimäki-Vire, Jonna et al.

Part of Nature Biotechnology, p. 1042-1055, 2022

Paracrine control of α-cell glucagon exocytosis is compromised in human type-2 diabetes.

Omar-Hmeadi, Muhmmad; Lund, Per-Eric; Gandasi, Nikhil; Tengholm, Anders et al.

Part of Nature Communications, 2020

Ca²⁺ channel clustering with insulin-containing granules is disturbed in type 2 diabetes

Gandasi, Nikhil R.; Yin, Peng; Riz, Michela; Chibalina, Margarita V et al.

Part of Journal of Clinical Investigation, p. 2353-2364, 2017

3-Oxoisoindoline-1-carboxamides: Potent, State-Dependent Blockers of Voltage-Gated Sodium Channel Na(V)1.7 with Efficacy in Rat Pain Models

Macsari, Istvan; Besidski, Yeygeni; Csjernyik, Gabor; Nilsson, Linda I. et al.

Part of Journal of Medicinal Chemistry, p. 6866-6880, 2012

DOI for 3-Oxoisoindoline-1-carboxamides: Potent, State-Dependent Blockers of Voltage-Gated Sodium Channel Na(V)1.7 with Efficacy in Rat Pain Models

Phenyl isoxazole voltage-gated sodium channel blockers: structure and activity relationship

Macsari, Istvan; Sandberg, Lars; Besidski, Yevgeni; Gravenfors, Ylva et al.

Part of Bioorganic & Medicinal Chemistry Letters, p. 3871-3876, 2011

DOI for Phenyl isoxazole voltage-gated sodium channel blockers: structure and activity relationship

Ryanodine receptor-operated activation of TRP-like channels can trigger critical Ca2+ signaling events in pancreatic beta-cells

Gustafsson, Amanda Jabin; Ingelman-Sundberg, Hanna; Dzabic, Mensur; Awasum, Justina et al.

Part of The FASEB Journal, p. 301-303, 2005

DOI for Ryanodine receptor-operated activation of TRP-like channels can trigger critical Ca2+ signaling events in pancreatic beta-cells

Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin I.

Voets, T; Moser, T; Lund, P E; Chow, R H et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 11680-5, 2001

DOI for Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin I.

The orexin OX1 receptor activates a novel Ca2+ influx pathway necessary for coupling to phospholipase C.

Lund, P E; Shariatmadari, R; Uustare, A; Detheux, M et al.

Part of Journal of Biological Chemistry, p. 30806-12, 2000

DOI for The orexin OX1 receptor activates a novel Ca2+ influx pathway necessary for coupling to phospholipase C.

The orexin OX(1) receptor activates a novel Ca2+ influx pathway necessary for coupling to phospholipase C*

Lund, Per-Eric; Shariatmadari, Ramin; Uustare, Ain; Detheux, M et al.

Part of J Biol Chem, p. 30806, 2000

Endogenous extracellular purine nucleotides redirect alpha2-adrenoceptor signaling

Akerman, Karl E. O.; Nasman, Johnny; Lund, Per-Eric; Shariatmadari, Ramin et al.

Part of FEBS Lett., p. 209, 1998

Characterization of recombinant human P2X4 receptor reveals pharmacological differences to the rat homologue.

Garcia-Guzman, M; Soto, F; Gomez-Hernandez, J M; Lund, P E et al.

Part of Molecular Pharmacology, p. 109-18, 1997

Stimulation of insulin release by isosmolar addition of permeant molecules.

Lund, P E; Berts, A; Hellman, B

Part of Molecular and Cellular Biochemistry, p. 77-81, 1992

Activation of G-proteins induces Ca2+ oscillations with hyperpolarizing K+ currents in pancreatic beta-cells.

Lund, P E; Hellman, B

Part of Second messengers and phosphoproteins, p. 173-83, 1991

Leucine induces initial lowering of cytoplasmic Ca2+ in pancreatic beta-cells without concomitant inhibition of insulin release.

Lund, P E; Gylfe, E; Hellman, B

Part of Biochemistry international, p. 83-7, 1989

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