Wilhelm Graf
Professor at Department of Surgical Sciences; Gastro intestinal Surgery
- Telephone:
- +46 18 611 46 06
- Mobile phone:
- +46 70 349 88 83
- Fax:
- +46 18 611 46 32
- E-mail:
- wilhelm.graf@uu.se
- Visiting address:
- Akademiska sjukhuset, ingång 70, 1 tr
751 85 UPPSALA - Postal address:
- Akademiska sjukhuset, ingång 70, 1 tr
751 85 UPPSALA

Publications
Recent publications
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Part of International Journal of Hyperthermia, 2026
- DOI for Survival and morbidity in elderly patients treated with cytoreductive surgery and HIPEC for colorectal peritoneal metastases: a population-based study
- Download full text (pdf) of Survival and morbidity in elderly patients treated with cytoreductive surgery and HIPEC for colorectal peritoneal metastases: a population-based study
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Part of Cell Reports, 2025
- DOI for Maturation of Human Intestinal Epithelial Cell Layers Fortifies the Apical Surface against Salmonella Attack
- Download full text (pdf) of Maturation of Human Intestinal Epithelial Cell Layers Fortifies the Apical Surface against Salmonella Attack
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Part of Pleura and Peritoneum, p. 59-68, 2025
- DOI for The impact of surgical staging in patients with colorectal peritoneal metastases scheduled for CRS-HIPEC
- Download full text (pdf) of The impact of surgical staging in patients with colorectal peritoneal metastases scheduled for CRS-HIPEC
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Part of Nature Genetics, p. 1730-1741, 2025
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Part of mBio, p. 1-22, 2025
- DOI for Determinants of divergent Salmonella and Shigella epithelial colonization strategies resolved in human enteroids and colonoids
- Download full text (pdf) of Determinants of divergent Salmonella and Shigella epithelial colonization strategies resolved in human enteroids and colonoids
All publications
Articles in journal
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Part of International Journal of Hyperthermia, 2026
- DOI for Survival and morbidity in elderly patients treated with cytoreductive surgery and HIPEC for colorectal peritoneal metastases: a population-based study
- Download full text (pdf) of Survival and morbidity in elderly patients treated with cytoreductive surgery and HIPEC for colorectal peritoneal metastases: a population-based study
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Part of Cell Reports, 2025
- DOI for Maturation of Human Intestinal Epithelial Cell Layers Fortifies the Apical Surface against Salmonella Attack
- Download full text (pdf) of Maturation of Human Intestinal Epithelial Cell Layers Fortifies the Apical Surface against Salmonella Attack
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Part of Pleura and Peritoneum, p. 59-68, 2025
- DOI for The impact of surgical staging in patients with colorectal peritoneal metastases scheduled for CRS-HIPEC
- Download full text (pdf) of The impact of surgical staging in patients with colorectal peritoneal metastases scheduled for CRS-HIPEC
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Part of Nature Genetics, p. 1730-1741, 2025
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Part of mBio, p. 1-22, 2025
- DOI for Determinants of divergent Salmonella and Shigella epithelial colonization strategies resolved in human enteroids and colonoids
- Download full text (pdf) of Determinants of divergent Salmonella and Shigella epithelial colonization strategies resolved in human enteroids and colonoids
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Part of Annals of Surgical Oncology, p. 3690-3690, 2025
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Part of Annals of Surgical Oncology, p. 3638-3647, 2025
- DOI for Patterns of Preoperative Tumor Markers Can Predict Resectability and Prognosis of Peritoneal Metastases: A Clustering Analysis
- Download full text (pdf) of Patterns of Preoperative Tumor Markers Can Predict Resectability and Prognosis of Peritoneal Metastases: A Clustering Analysis
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Appendiceal adenocarcinoma-patterns of tumor spread and prognosis
Part of European Journal of Surgical Oncology, 2025
- DOI for Appendiceal adenocarcinoma-patterns of tumor spread and prognosis
- Download full text (pdf) of Appendiceal adenocarcinoma-patterns of tumor spread and prognosis
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Part of Journal of Gastrointestinal Cancer, 2025
- DOI for The Extent of Tumor in the Peritoneum and Liver Influences Outcomes After Surgery for Synchronous Liver and Peritoneal Colorectal Metastases: A Cohort Study
- Download full text (pdf) of The Extent of Tumor in the Peritoneum and Liver Influences Outcomes After Surgery for Synchronous Liver and Peritoneal Colorectal Metastases: A Cohort Study
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Part of Journal of Surgical Oncology, p. 1395-1402, 2024
- DOI for Eighteen-Months Safety and Efficacy Following Intraperitoneal Treatment With 224Radium-Labeled Microparticles After CRS-HIPEC in Patients With Peritoneal Metastasis From Colorectal Cancer
- Download full text (pdf) of Eighteen-Months Safety and Efficacy Following Intraperitoneal Treatment With 224Radium-Labeled Microparticles After CRS-HIPEC in Patients With Peritoneal Metastasis From Colorectal Cancer
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Part of British Journal of Surgery, 2024
- DOI for Evaluation of laparoscopic peritoneal lavage for perforated diverticulitis: a national registry-based study
- Download full text (pdf) of Evaluation of laparoscopic peritoneal lavage for perforated diverticulitis: a national registry-based study
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Part of International Journal of Surgery, p. 7187-7195, 2024
- DOI for Clinical significance of circulating tumor cells in colorectal cancer with peritoneal metastases: a prospective cohort study using a novel method for monitoring treatment response, and assessing minimal residual disease
- Download full text (pdf) of Clinical significance of circulating tumor cells in colorectal cancer with peritoneal metastases: a prospective cohort study using a novel method for monitoring treatment response, and assessing minimal residual disease
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Part of International Journal of Hyperthermia, 2024
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Part of Cancers, 2024
- DOI for Clinical Significance of Circulating Tumor Cells in Epithelial Appendiceal Neoplasms with Peritoneal Metastases
- Download full text (pdf) of Clinical Significance of Circulating Tumor Cells in Epithelial Appendiceal Neoplasms with Peritoneal Metastases
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Part of Surgery Open Science, p. 45-50, 2024
- DOI for Secondary cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for recurrent colorectal peritoneal metastases
- Download full text (pdf) of Secondary cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for recurrent colorectal peritoneal metastases
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No Indication for Routine Resection of Surgical Scars during Cytoreductive Surgery and HIPEC
Part of Cancers, 2024
- DOI for No Indication for Routine Resection of Surgical Scars during Cytoreductive Surgery and HIPEC
- Download full text (pdf) of No Indication for Routine Resection of Surgical Scars during Cytoreductive Surgery and HIPEC
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Part of PLOS ONE, 2024
- DOI for Efficacy of hyperthermic intraperitoneal chemotherapy in colorectal cancer: A phase I and III open label randomized controlled registry-based clinical trial protocol
- Download full text (pdf) of Efficacy of hyperthermic intraperitoneal chemotherapy in colorectal cancer: A phase I and III open label randomized controlled registry-based clinical trial protocol
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Part of Clinical Gastroenterology and Hepatology, p. 476-48600000000, 2023
- DOI for Skeletal Muscle-Derived Cell Implantation for the Treatment of Fecal Incontinence: A Randomized, Placebo-Controlled Study
- Download full text (pdf) of Skeletal Muscle-Derived Cell Implantation for the Treatment of Fecal Incontinence: A Randomized, Placebo-Controlled Study
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Part of European Journal of Surgical Oncology, p. 1474-1480, 2023
- DOI for The Impact on Postoperative Outcomes of Intraoperative Fluid Management Strategies During Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
- Download full text (pdf) of The Impact on Postoperative Outcomes of Intraoperative Fluid Management Strategies During Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
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Part of Frontiers in Medicine, 2023
- DOI for First experience with (224)Radium-labeled microparticles (Radspherin (R)) after CRS-HIPEC for peritoneal metastasis in colorectal cancer (a phase 1 study)
- Download full text (pdf) of First experience with (224)Radium-labeled microparticles (Radspherin (R)) after CRS-HIPEC for peritoneal metastasis in colorectal cancer (a phase 1 study)
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Part of BJS Open, 2022
- DOI for Author response to: Comparison of four surgical approaches for rectal prolapse: multicentre randomized clinical trial
- Download full text (pdf) of Author response to: Comparison of four surgical approaches for rectal prolapse: multicentre randomized clinical trial
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Comparison of four surgical approaches for rectal prolapse: multicentre randomized clinical trial
Part of BJS Open, 2022
- DOI for Comparison of four surgical approaches for rectal prolapse: multicentre randomized clinical trial
- Download full text (pdf) of Comparison of four surgical approaches for rectal prolapse: multicentre randomized clinical trial
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Part of European Journal of Surgical Oncology, p. 666-671, 2022
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Surgical treatment of rectovaginal fistula-predictors of outcome and effects on quality of life
Part of International Journal of Colorectal Disease, p. 1699-1707, 2022
- DOI for Surgical treatment of rectovaginal fistula-predictors of outcome and effects on quality of life
- Download full text (pdf) of Surgical treatment of rectovaginal fistula-predictors of outcome and effects on quality of life
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Part of European Journal of Surgical Oncology, p. 1598-1605, 2022
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A short- and long-term follow-up study of intersphincteric NASHA Dx implants for fecal incontinence
Part of Techniques in Coloproctology, p. 813-820, 2022
- DOI for A short- and long-term follow-up study of intersphincteric NASHA Dx implants for fecal incontinence
- Download full text (pdf) of A short- and long-term follow-up study of intersphincteric NASHA Dx implants for fecal incontinence
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Part of PLOS ONE, 2021
- DOI for Severe pulmonary complications after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy are common and contribute to decreased overall survival.
- Download full text (pdf) of Severe pulmonary complications after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy are common and contribute to decreased overall survival.
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Part of Advances in Medical Education and Practice, p. 597-605, 2021
- DOI for A New Hybrid Concept, Combining Lectures and Case-Seminars, Resulted in Superior Ratings from Both Undergraduate Medical Students and Teachers
- Download full text (pdf) of A New Hybrid Concept, Combining Lectures and Case-Seminars, Resulted in Superior Ratings from Both Undergraduate Medical Students and Teachers
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Peritoneal cancer index predicts severe complications after ovarian cancer surgery
Part of European Journal of Surgical Oncology, p. 2915-2924, 2021
- DOI for Peritoneal cancer index predicts severe complications after ovarian cancer surgery
- Download full text (pdf) of Peritoneal cancer index predicts severe complications after ovarian cancer surgery
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Part of Annals of Surgical Oncology, p. 440-440, 2021
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Part of Annals of Surgical Oncology, p. 7772-7782, 2021
- DOI for Coagulopathy and Venous Thromboembolic Events Following Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
- Download full text (pdf) of Coagulopathy and Venous Thromboembolic Events Following Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
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Long-term functional results after excisional haemorrhoidectomy
Part of Colorectal Disease, p. 824-830, 2020
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Part of Journal of Pediatric Surgery, p. 397-402, 2020
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Part of World Journal of Surgical Oncology, 2020
- DOI for Readmissions after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy-a national population-based study
- Download full text (pdf) of Readmissions after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy-a national population-based study
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Part of Open Journal of Obstetrics and Gynecology, p. 729-737, 2020
- DOI for Change in Deferring Time Correlate to Improved Female Sexual Function after Anal Sphincter Repair: A Prospective Study
- Download full text (pdf) of Change in Deferring Time Correlate to Improved Female Sexual Function after Anal Sphincter Repair: A Prospective Study
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Part of Annals of Surgical Oncology, p. 293-300, 2020
- DOI for Prognostic Impact of BRAF and KRAS Mutation in Patients with Colorectal and Appendiceal Peritoneal Metastases Scheduled for CRS and HIPEC
- Download full text (pdf) of Prognostic Impact of BRAF and KRAS Mutation in Patients with Colorectal and Appendiceal Peritoneal Metastases Scheduled for CRS and HIPEC
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Part of Annals of Surgical Oncology, p. 301-302, 2020
- DOI for ASO Author Reflections: Can Patient Selection for Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy be Improved?
- Download full text (pdf) of ASO Author Reflections: Can Patient Selection for Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy be Improved?
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Part of European Journal of Surgical Oncology, p. 2283-2291, 2020
- DOI for Patients with colorectal peritoneal metastases and high peritoneal cancer index may benefit from cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
- Download full text (pdf) of Patients with colorectal peritoneal metastases and high peritoneal cancer index may benefit from cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
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Patterns of tined lead migration in sacral nerve modulation
Part of International Journal of Colorectal Disease, p. 1163-1166, 2020
- DOI for Patterns of tined lead migration in sacral nerve modulation
- Download full text (pdf) of Patterns of tined lead migration in sacral nerve modulation
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Long-term outcome after segmental colonic resection for slow transit constipation
Part of International Journal of Colorectal Disease, p. 1013-1019, 2019
- DOI for Long-term outcome after segmental colonic resection for slow transit constipation
- Download full text (pdf) of Long-term outcome after segmental colonic resection for slow transit constipation
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Persistent fecal incontinence into adulthood after repair of anorectal malformations
Part of International Journal of Colorectal Disease, p. 551-554, 2019
- DOI for Persistent fecal incontinence into adulthood after repair of anorectal malformations
- Download full text (pdf) of Persistent fecal incontinence into adulthood after repair of anorectal malformations
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Peritoneal mesothelioma in Sweden: A population-based study
Part of Cancer Medicine, p. 6468-6475, 2019
- DOI for Peritoneal mesothelioma in Sweden: A population-based study
- Download full text (pdf) of Peritoneal mesothelioma in Sweden: A population-based study
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Part of Annals of Surgical Oncology, p. 4835-4842, 2019
- DOI for Gains of Chromosome 1p and 15q are Associated with Poor Survival After Cytoreductive Surgery and HIPEC for Treating Colorectal Peritoneal Metastases
- Download full text (pdf) of Gains of Chromosome 1p and 15q are Associated with Poor Survival After Cytoreductive Surgery and HIPEC for Treating Colorectal Peritoneal Metastases
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Reduced Need for In-hospital Care After Sleeve Gastrectomy: a Single Center Observational Study
Part of Obesity Surgery, p. 3228-3231, 2019
- DOI for Reduced Need for In-hospital Care After Sleeve Gastrectomy: a Single Center Observational Study
- Download full text (pdf) of Reduced Need for In-hospital Care After Sleeve Gastrectomy: a Single Center Observational Study
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Part of European journal of pediatric surgery, p. 276-281, 2019
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Part of Surgery for Obesity and Related Diseases, p. 144-149, 2018
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Risk factors for appendiceal and colorectal peritoneal metastases
Part of European Journal of Surgical Oncology, p. 997-1005, 2018
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Part of European Journal of Surgical Oncology, p. 983-990, 2018
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Increased incidence of bowel cancer after non-surgical treatment of appendicitis
Part of European Journal of Surgical Oncology, p. 2067-2075, 2017
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Part of Journal of Pediatric Surgery, p. 463-468, 2017
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Long-term outcome after surgery for Crohn's anal fistula
Part of Colorectal Disease, p. 80-85, 2016
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Part of Annals of Surgical Oncology, p. 1149-1156, 2016
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Part of International Journal of Colorectal Disease, p. 1383-1384, 2016
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Part of European Journal of Cancer, p. 155-162, 2016
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Part of International Journal of Colorectal Disease, p. 1205-1216, 2016
- DOI for Libertas: a phase II placebo-controlled study of NRL001 in patients with faecal incontinence showed an unexpected and sustained placebo response
- Download full text (pdf) of Libertas: a phase II placebo-controlled study of NRL001 in patients with faecal incontinence showed an unexpected and sustained placebo response
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Complications Related To Surgery For Ovarian Cancer With Intestinal Involvement
Part of International Journal of Gynecological Cancer, p. 492-492, 2015
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Part of Annals of Surgical Oncology, 2015
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Part of Annals of Surgery, 2015
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Part of Journal of Pediatric Surgery, p. 1556-1559, 2015
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Results after sacral nerve stimulation for chronic constipation
Part of Neurogastroenterology and Motility, p. 734-739, 2015
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Part of Scandinavian Journal of Gastroenterology, p. 1073-1083, 2014
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Long-term efficacy of NASHA Dx injection therapy for treatment of fecal incontinence
Part of Neurogastroenterology and Motility, p. 1087-1094, 2014
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Part of BMC Cancer, p. 435, 2013
- DOI for Activity ex vivo of cytotoxic drugs in patient samples of peritoneal carcinomatosis with special focus on colorectal cancer
- Download full text (pdf) of Activity ex vivo of cytotoxic drugs in patient samples of peritoneal carcinomatosis with special focus on colorectal cancer
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Part of Colorectal Disease, p. 341-346, 2013
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Efficacy of LIFT for recurrent anal fistula
Part of Colorectal Disease, p. 592-595, 2013
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Part of Annals of Surgical Oncology, p. 4183-4189, 2013
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Part of Techniques in Coloproctology, p. 389-395, 2013
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Part of Diseases of the Colon & Rectum, p. 903-908, 2013
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Cytoreductive surgery in pseudomyxoma peritonei-aspects of the learning curve
Part of European Journal of Surgical Oncology, p. 930-936, 2013
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Part of Annals of Surgery, 2012
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Part of Anticancer Research, p. 1443-1448, 2012
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Part of Annals of Oncology, p. 647-652, 2012
- DOI for Intraoperative hyperthermic versus postoperative normothermic intraperitoneal chemotherapy for colonic peritoneal carcinomatosis: a case-control study
- Download full text (pdf) of Intraoperative hyperthermic versus postoperative normothermic intraperitoneal chemotherapy for colonic peritoneal carcinomatosis: a case-control study
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Ultrasonography findings and tumour quantification in patients with pseudomyxoma peritonei
Part of European Journal of Radiology, p. 648-651, 2012
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Part of European Journal of Surgical Oncology, p. 962-968, 2012
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Response to comments on 'Cytoreductive surgery and intraperitoneal chemotherapy'
Part of European Journal of Surgical Oncology, p. 1012-1012, 2012
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Part of Annals of Surgery, p. 1078-1083, 2012
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Part of European Journal of Surgical Oncology, p. 509-515, 2012
- DOI for Cytoreductive Surgery and Intraperitoneal Chemotherapy for Colorectal Peritoneal Carcinomatosis: Prognosis and Treatment of Recurrences in a Cohort Study
- Download full text (pdf) of Cytoreductive Surgery and Intraperitoneal Chemotherapy for Colorectal Peritoneal Carcinomatosis: Prognosis and Treatment of Recurrences in a Cohort Study
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Genomic disorders on chromosome 22
Part of Current opinion in pediatrics, p. 665-671, 2012
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Part of The Lancet, p. 997-1003, 2011
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Novel activity of acriflavine against colorectal cancer tumor cells
Part of Cancer Science, p. 2206-2213, 2011
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Part of Diseases of the Colon & Rectum, p. 300-305, 2011
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Part of Journal of Pediatric Surgery, p. 2036-2040, 2010
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Part of Läkartidningen, p. 682-684, 2010
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Part of Diseases of the Colon & Rectum, p. 1101-1106, 2009
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Part of European Journal of Gastroenterology and Hepathology, p. 176-182, 2009
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Kirurgi – omistligt komplement till medicinsk behandling
Part of Läkartidningen, p. 3003-9, 2009
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Part of European Journal of Surgical Oncology, p. 202-208, 2009
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Heterogeneous activity of cytotoxic drugs in patient samples of peritoneal carcinomatosis
Part of European Journal of Surgical Oncology, p. 547-552, 2008
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Swedish experience with peritonectomy and HIPEC: HIPEC in peritoneal carcinomatosis
Part of Annals of Surgical Oncology, p. 745-53, 2008
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The role of maternal age and episiotomy in the risk of anal sphincter tears during childbirth
Part of Australian and New Zealand journal of obstetrics and gynaecology, p. 286-290, 2007
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Segmental colonic transit studies: Comparison of a radiological and a scintigraphic method
Part of Colorectal Disease, p. 344-351, 2007
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Anorectal manovolumetry in the decision making before surgery for slow transit constipation
Part of Techniques in Coloproctology, p. 259-265, 2007
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Part of British Journal of Surgery, p. 122-122, 2007
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Part of British Journal of Surgery, p. 1202-1207, 2006
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Part of British Journal of Surgery, p. 1208-1214, 2006
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Die Genauigkeit der klinischen Untersuchung bei der Diagnose der rektalen Invagination
Part of Coloproctology, p. 78-84, 2005
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Part of Anticancer Research, p. 917-922, 2005
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Bowel habits in hemorrhoid patients and normal subjects.
Part of Am J Gastroenterol, p. 401-6, 2005
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Part of Dis Colon Rectum, p. 1923-9, 2005
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Part of BJS, p. 1131-7, 2004
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Part of European Journal of Cancer, p. 142-147, 2004
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Anorectal physiology in relation to clinical subgroups of patients with severe constipation.
Part of Colorectal Dis, p. 343-9, 2004
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The accuracy of clinical examination in the diagnosis of rectal intussusception.
Part of Dis Colon Rectum, p. 1533-8, 2004
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Part of Br J Cancer, p. 403-7, 2004
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Outcome of segmental colonic resection for slow-transit constipation.
Part of British Journal of Surgery, 2002
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Part of Anticancer Research, p. 943-949, 1998
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Part of Anticancer Research, p. 843-848, 1998
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Randomized Clinical Trial of Milligan-Morgan versus Ferguson Haemorrhoidectomy
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Anorectal physiology in the decision making before surgery for slow transit constipation
Articles, review/survey
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Part of Scandinavian Journal of Gastroenterology, p. 543-546, 2024
- DOI for Diarrhoea of unknown cause: medical treatment in a stepwise manner: Management of Idiopathic Diarrhoea Based on Experience of Step-Up Medical Treatment
- Download full text (pdf) of Diarrhoea of unknown cause: medical treatment in a stepwise manner: Management of Idiopathic Diarrhoea Based on Experience of Step-Up Medical Treatment
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Part of Cancers, 2024
- DOI for Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Metastases from Colorectal Cancer-An Overview of Current Status and Future Perspectives
- Download full text (pdf) of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Metastases from Colorectal Cancer-An Overview of Current Status and Future Perspectives
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Part of Läkartidningen, 2023
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Part of World Journal of Surgical Oncology, 2022
- DOI for The prognostic impact of lead times in colorectal cancer patients undergoing cytoreductive surgery and HIPEC
- Download full text (pdf) of The prognostic impact of lead times in colorectal cancer patients undergoing cytoreductive surgery and HIPEC
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Part of Journal of Gastrointestinal Oncology, 2021
- DOI for Sequential postoperative intraperitoneal chemotherapy for colorectal cancer with peritoneal metastases: a narrative review
- Download full text (pdf) of Sequential postoperative intraperitoneal chemotherapy for colorectal cancer with peritoneal metastases: a narrative review
Chapters in book
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Part of Kirurgi, p. 357-364, Liber, 2017
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Part of Kirurgi, p. 288-348, Liber, 2017
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Part of Läkemedelsboken, p. 142-149, Apoteket AB, 2009
Manuscripts (preprints)
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2012
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Factors associated with the risk of idiopathic anal fistula disease: a case-control study
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Intraoperative changes in mucosal blood flow in advancement flap repair of anal fistula.
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Prognostic importance of genetic alterations in colorectal peritoneal metastases
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Prehabilitation before surgery for peritoneal malignancies: a scoping review