Sandra Kleinau

Proteolysis Breaks Tolerance toward Intact alpha 345(IV) Collagen, Eliciting Novel Anti-Glomerular Basement Membrane Autoantibodies Specific for alpha 345NC1 Hexamers

Olaru, Florina; Wang, Xu-Ping; Luo, Wentian; Ge, Linna et al.

Part of Journal of Immunology, p. 1424-1432, 2013

• DOI for Proteolysis Breaks Tolerance toward Intact alpha 345(IV) Collagen, Eliciting Novel Anti-Glomerular Basement Membrane Autoantibodies Specific for alpha 345NC1 Hexamers

Up Regulated Complement and Fc Receptors in Juvenile Idiopathic Arthritis and Correlation with Disease Phenotype

Prokopec, Kajsa E.; Berntson, Lillemor; Öman, Anders; Kleinau, Sandra

Part of Journal of Clinical Immunology, p. 540-550, 2012

• DOI for Up Regulated Complement and Fc Receptors in Juvenile Idiopathic Arthritis and Correlation with Disease Phenotype

Murine Membranous Nephropathy: Immunization with alpha 3(IV) Collagen Fragment Induces Subepithelial Immune Complexes and Fc gamma R-Independent Nephrotic Syndrome

Zhang, Jun-Jun; Malekpour, Mahdi; Luo, Wentian; Ge, Linna et al.

Part of Journal of Immunology, p. 3268-3277, 2012

• DOI for Murine Membranous Nephropathy: Immunization with alpha 3(IV) Collagen Fragment Induces Subepithelial Immune Complexes and Fc gamma R-Independent Nephrotic Syndrome

Marginal zone B cells are naturally reactive to collagen type II and are involved in the initiation of the immune response in collagen-induced arthritis

Carnrot, Cecilia; Prokopec, Kajsa; Råsbo, Kristina; Karlsson, Mikael et al.

Part of Cellular & Molecular Immunology, p. 296-304, 2011

• DOI for Marginal zone B cells are naturally reactive to collagen type II and are involved in the initiation of the immune response in collagen-induced arthritis
• Download full text (pdf) of Marginal zone B cells are naturally reactive to collagen type II and are involved in the initiation of the immune response in collagen-induced arthritis

IgG immune complex-binding in macrophages from arthritis-susceptible and arthritis-resistant mice following collagen type II immunization.

Thorvaldson, L; Fuchs, D; Magnusson, S; Kleinau, S

Part of Scandinavian Journal of Immunology, p. 347-54, 2006

FcgammaRIII-expressing macrophages are essential for development of collagen-induced arthritis.

Andrén, M; Xiang, Z; Nilsson, G; Kleinau, S

Part of Scand J Immunol, p. 282-9, 2006

Gene targeting by ribozyme against TNF-alpha mRNA inhibits autoimmune arthritis.

Kumar, R; Dammai, V; Yadava, P K; Kleinau, S

Part of Gene Ther, p. 1486-93, 2005

IgG Fc receptor polymorphisms and association with autoimmune disease.

Andrén, Maria; Johanneson, Bo; Alarcon Riquelme, Marta E; Kleinau, Sandra

Part of Eur J Immunol, p. 3020-9, 2005

Induction of arthritis by single monoclonal IgG anti-collagen type II antibodies and enhancement of arthritis in mice lacking inhibitory FcgammaRIIB.

Nandakumar, Kutty Selva; Andrén, Maria; Martinsson, Pernilla; Bajtner, Estelle et al.

Part of Eur J Immunol, p. 2269-77, 2003

The impact of Fc receptors on the development of autoimmune diseases.

Kleinau, S

Part of Curr Pharm Des, p. 1861-70, 2003

Human problems - animal models: Aspects on the use of inducible experimental arthritis for pathogenetic studies of human inflammatory joint disease

Klareskog, L; Kleinau, S; Ulfgren, A; Mussener, Å et al.

Part of Rheumatology Highligths 95 Rheumatology in Europe, p. 8, 1995

Rituximab-IgG2 is a phagocytic enhancer in antibody-based immunotherapy of B-cell lymphoma by altering CD47 expression

Nguyen, Oanh T. P.; Lara, Sandra; Ferro, Giovanni; Peipp, Matthias et al.

Part of Frontiers in Immunology, 2024

• DOI for Rituximab-IgG2 is a phagocytic enhancer in antibody-based immunotherapy of B-cell lymphoma by altering CD47 expression
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Impact of Fc receptors and host characteristics on myeloid phagocytic response to rituximab-treated 3D-cultured B-cell lymphoma

Kleinau, Sandra

Part of IMMUNOTHERAPY ADVANCES, 2023

• DOI for Impact of Fc receptors and host characteristics on myeloid phagocytic response to rituximab-treated 3D-cultured B-cell lymphoma
• Download full text (pdf) of Impact of Fc receptors and host characteristics on myeloid phagocytic response to rituximab-treated 3D-cultured B-cell lymphoma

Quantitative In-Depth Transcriptome Analysis Implicates Peritoneal Macrophages as Important Players in the Complement and Coagulation Systems

Paivandy, Aida; Akula, Srinivas; Lara, Sandra; Fu, Zhirong et al.

Part of International Journal of Molecular Sciences, 2022

• DOI for Quantitative In-Depth Transcriptome Analysis Implicates Peritoneal Macrophages as Important Players in the Complement and Coagulation Systems
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Exploring complement-dependent cytotoxicity by rituximab isotypes in 2D and 3D-cultured B-cell lymphoma

Lara, Sandra; Heilig, Juliane; Virtanen, Alexander; Kleinau, Sandra

Part of BMC Cancer, 2022

• DOI for Exploring complement-dependent cytotoxicity by rituximab isotypes in 2D and 3D-cultured B-cell lymphoma
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The Human Monocyte: A Circulating Sensor of Infection and a Potent and Rapid Inducer of Inflammation

Lara, Sandra; Akula, Srinivas; Fu, Zhirong; Olsson, Anna-Karin et al.

Part of International Journal of Molecular Sciences, 2022

• DOI for The Human Monocyte: A Circulating Sensor of Infection and a Potent and Rapid Inducer of Inflammation
• Download full text (pdf) of The Human Monocyte: A Circulating Sensor of Infection and a Potent and Rapid Inducer of Inflammation

Rituximab-IgG2 is a phagocytic enhancer in antibody-based immunotherapy of B-cell lymphoma by altering CD47 expression

Nguyen, Oanh T. P.; Lara, Sandra; Ferro, Giovanni; Peipp, Matthias et al.

Part of Frontiers in Immunology, 2024

• DOI for Rituximab-IgG2 is a phagocytic enhancer in antibody-based immunotherapy of B-cell lymphoma by altering CD47 expression
• Download full text (pdf) of Rituximab-IgG2 is a phagocytic enhancer in antibody-based immunotherapy of B-cell lymphoma by altering CD47 expression

Impact of Fc receptors and host characteristics on myeloid phagocytic response to rituximab-treated 3D-cultured B-cell lymphoma

Kleinau, Sandra

Part of IMMUNOTHERAPY ADVANCES, 2023

• DOI for Impact of Fc receptors and host characteristics on myeloid phagocytic response to rituximab-treated 3D-cultured B-cell lymphoma
• Download full text (pdf) of Impact of Fc receptors and host characteristics on myeloid phagocytic response to rituximab-treated 3D-cultured B-cell lymphoma

Quantitative In-Depth Transcriptome Analysis Implicates Peritoneal Macrophages as Important Players in the Complement and Coagulation Systems

Paivandy, Aida; Akula, Srinivas; Lara, Sandra; Fu, Zhirong et al.

Part of International Journal of Molecular Sciences, 2022

• DOI for Quantitative In-Depth Transcriptome Analysis Implicates Peritoneal Macrophages as Important Players in the Complement and Coagulation Systems
• Download full text (pdf) of Quantitative In-Depth Transcriptome Analysis Implicates Peritoneal Macrophages as Important Players in the Complement and Coagulation Systems

Exploring complement-dependent cytotoxicity by rituximab isotypes in 2D and 3D-cultured B-cell lymphoma

Lara, Sandra; Heilig, Juliane; Virtanen, Alexander; Kleinau, Sandra

Part of BMC Cancer, 2022

• DOI for Exploring complement-dependent cytotoxicity by rituximab isotypes in 2D and 3D-cultured B-cell lymphoma
• Download full text (pdf) of Exploring complement-dependent cytotoxicity by rituximab isotypes in 2D and 3D-cultured B-cell lymphoma

The Human Monocyte: A Circulating Sensor of Infection and a Potent and Rapid Inducer of Inflammation

Lara, Sandra; Akula, Srinivas; Fu, Zhirong; Olsson, Anna-Karin et al.

Part of International Journal of Molecular Sciences, 2022

• DOI for The Human Monocyte: A Circulating Sensor of Infection and a Potent and Rapid Inducer of Inflammation
• Download full text (pdf) of The Human Monocyte: A Circulating Sensor of Infection and a Potent and Rapid Inducer of Inflammation

Marginal zone B cells: From housekeeping function to autoimmunity?

Palm, Anna-Karin E.; Kleinau, Sandra

Part of Journal of Autoimmunity, 2021

• DOI for Marginal zone B cells: From housekeeping function to autoimmunity?
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Importance of antibody isotypes in antitumor immunity by monocytes and complement using human-immune tumor models

Lara, Sandra; Anania, Jessica; Virtanen, Alexander; Stenhammar, Viktoria et al.

Part of European Journal of Immunology, p. 1218-1233, 2021

• DOI for Importance of antibody isotypes in antitumor immunity by monocytes and complement using human-immune tumor models
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On The Relationship between Rheumatoid Factors, Monocyte Subsets and FC Receptor Function in Early Ra

Matt, Peter; Lindqvist, Ulla; Kleinau, Sandra

Part of Annals of the Rheumatic Diseases, p. 695-695, 2016

• DOI for On The Relationship between Rheumatoid Factors, Monocyte Subsets and FC Receptor Function in Early Ra

Nodal marginal zone B cells in mice: a novel subset with dormant self-reactivity

Palm, Anna-Karin E.; Friedrich, Heike C.; Kleinau, Sandra

Part of Scientific Reports, 2016

• DOI for Nodal marginal zone B cells in mice: a novel subset with dormant self-reactivity
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Activated mast cells promote differentiation of B cells into effector cells

Palm, Anna-Karin E.; Garcia-Faroldi, Gianni; Lundberg, Marcus; Pejler, Gunnar et al.

Part of Scientific Reports, 2016

• DOI for Activated mast cells promote differentiation of B cells into effector cells

Identification of self-reactive marginal-zone B cell like cells in lymph nodes of mice

Palm, Anna-Karin E.; Friedrich, H. C.; Kleinau, Sandra

Part of European Journal of Immunology, p. 931-931, 2016

Elevated Membrane and Soluble CD64: A Novel Marker Reflecting Altered Fc gamma R Function and Disease in Early Rheumatoid Arthritis That Can Be Regulated by Anti-Rheumatic Treatment

Matt, Peter; Lindqvist, Ulla; Kleinau, Sandra

Part of PLOS ONE, 2015

• DOI for Elevated Membrane and Soluble CD64: A Novel Marker Reflecting Altered Fc gamma R Function and Disease in Early Rheumatoid Arthritis That Can Be Regulated by Anti-Rheumatic Treatment

Up-regulation of CD64-expressing monocytes with impaired Fc gamma R function reflects disease activity in polyarticular psoriatic arthritis

Matt, Peter; Lindqvist, Ulla; Kleinau, Sandra

Part of Scandinavian Journal of Rheumatology, p. 464-473, 2015

• DOI for Up-regulation of CD64-expressing monocytes with impaired Fc gamma R function reflects disease activity in polyarticular psoriatic arthritis

Function and regulation of self-reactive marginal zone B cells in autoimmune arthritis

Palm, Anna-Karin E.; Friedrich, Heike C.; Mezger, Anja; Salomonsson, Maya et al.

Part of Cellular & Molecular Immunology, p. 493-504, 2015

• DOI for Function and regulation of self-reactive marginal zone B cells in autoimmune arthritis

Identification of a Population of Lymph Node Marginal Zone B Cells that Expand in Mice Developing Autoimmune Arthritis

Palm, Anna-Karin E.; Friedrich, Heike C.; Mezger, Anja; Myers, Linda K. et al.

Part of Scandinavian Journal of Immunology, p. 230-230, 2014

Dysregulated Fc receptor function in active rheumatoid arthritis

Magnusson, Sofia E; Wennerberg, Erik; Matt, Peter; Lindqvist, Ulla et al.

Part of Immunology Letters, p. 200-206, 2014

• DOI for Dysregulated Fc receptor function in active rheumatoid arthritis

Evidence of Marginal Zone B Cells in the Lymph Nodes Presenting Autoantigen to T Cells in a Model of Autoimmune Arthritis

Palm, Anna-Karin; Friedrich, Heike; Myers, Linda; Kleinau, Sandra

Part of Scandinavian Journal of Immunology, p. 455-455, 2014

AB0102 Effects of anti-rheumatic treatment on antibody levels and monocytic fc receptor status in early ra

Matt, Peter; Rönnelid, Johan; Kleinau, Sandra; Lindqvist, Ulla

Part of Annals of the Rheumatic Diseases, 2013

• DOI for AB0102 Effects of anti-rheumatic treatment on antibody levels and monocytic fc receptor status in early ra

Expansion of a marginal zone B cell-like population in lymph nodes of mice developing collagen-induced arthritis

Palm, Anna-Karin; Kleinau, Sandra

Part of Journal of Immunology, 2013

Proteolysis Breaks Tolerance toward Intact alpha 345(IV) Collagen, Eliciting Novel Anti-Glomerular Basement Membrane Autoantibodies Specific for alpha 345NC1 Hexamers

Olaru, Florina; Wang, Xu-Ping; Luo, Wentian; Ge, Linna et al.

Part of Journal of Immunology, p. 1424-1432, 2013

• DOI for Proteolysis Breaks Tolerance toward Intact alpha 345(IV) Collagen, Eliciting Novel Anti-Glomerular Basement Membrane Autoantibodies Specific for alpha 345NC1 Hexamers

Molecular Basis for T Cell Response Induced by Altered Peptide Ligand of Type II Collagen

Park, Jeoung-Eun; Cullins, David; Zalduondo, Lillian; Barnett, Stacey L. et al.

Part of Journal of Biological Chemistry, p. 19765-19774, 2012

• DOI for Molecular Basis for T Cell Response Induced by Altered Peptide Ligand of Type II Collagen

Up Regulated Complement and Fc Receptors in Juvenile Idiopathic Arthritis and Correlation with Disease Phenotype

Prokopec, Kajsa E.; Berntson, Lillemor; Öman, Anders; Kleinau, Sandra

Part of Journal of Clinical Immunology, p. 540-550, 2012

• DOI for Up Regulated Complement and Fc Receptors in Juvenile Idiopathic Arthritis and Correlation with Disease Phenotype

Murine Membranous Nephropathy: Immunization with alpha 3(IV) Collagen Fragment Induces Subepithelial Immune Complexes and Fc gamma R-Independent Nephrotic Syndrome

Zhang, Jun-Jun; Malekpour, Mahdi; Luo, Wentian; Ge, Linna et al.

Part of Journal of Immunology, p. 3268-3277, 2012

• DOI for Murine Membranous Nephropathy: Immunization with alpha 3(IV) Collagen Fragment Induces Subepithelial Immune Complexes and Fc gamma R-Independent Nephrotic Syndrome

Marginal zone B cells in autoimmune arthritis

Palm, Anna-Karin E.; Kleinau, Sandra

Part of Immunology, p. 336-336, 2012

T Cells Stimulated With an Analog Peptide of Type II Collagen Require the Fc Receptor gamma-Chain to Secrete Interleukin-4 and Suppress Autoimmune Arthritis in Mice

Myers, Linda K.; Cullins, David L.; Brand, David D.; Kleinau, Sandra et al.

Part of Arthritis and Rheumatism, p. 2661-2670, 2011

• DOI for T Cells Stimulated With an Analog Peptide of Type II Collagen Require the Fc Receptor gamma-Chain to Secrete Interleukin-4 and Suppress Autoimmune Arthritis in Mice

Marginal zone B cells are naturally reactive to collagen type II and are involved in the initiation of the immune response in collagen-induced arthritis

Carnrot, Cecilia; Prokopec, Kajsa; Råsbo, Kristina; Karlsson, Mikael et al.

Part of Cellular & Molecular Immunology, p. 296-304, 2011

• DOI for Marginal zone B cells are naturally reactive to collagen type II and are involved in the initiation of the immune response in collagen-induced arthritis
• Download full text (pdf) of Marginal zone B cells are naturally reactive to collagen type II and are involved in the initiation of the immune response in collagen-induced arthritis

Enhanced susceptibility to low-dose collagen-induced arthritis in CR1/2-deficient female mice: possible role of estrogen on CR1 expression

Nilsson, Kajsa E.; Andrén, Maria; Diaz de Ståhl, Teresita; Kleinau, Sandra

Part of The FASEB Journal, p. 2450-2458, 2009

• DOI for Enhanced susceptibility to low-dose collagen-induced arthritis in CR1/2-deficient female mice: possible role of estrogen on CR1 expression

Amelioration of collagen-induced arthritis by human recombinant soluble FcγRIIb

Magnusson, Sofia; Andrén, Maria; Nilsson, Kajsa E; Sondermann, Peter et al.

Part of Clinical Immunology, p. 225-233, 2008

• DOI for Amelioration of collagen-induced arthritis by human recombinant soluble FcγRIIb

The effect of activating and inhibiting Fc-receptors on murine mercury-induced autoimmunity.

Martinsson, Klara; Carlsson, Louise; Kleinau, Sandra; Hultman, Per

Part of Journal of Autoimmunity, p. 22-29, 2008

• DOI for The effect of activating and inhibiting Fc-receptors on murine mercury-induced autoimmunity.

IgG immune complex-binding in macrophages from arthritis-susceptible and arthritis-resistant mice following collagen type II immunization.

Thorvaldson, L; Fuchs, D; Magnusson, S; Kleinau, S

Part of Scandinavian Journal of Immunology, p. 347-54, 2006

FcgammaRIII-expressing macrophages are essential for development of collagen-induced arthritis.

Andrén, M; Xiang, Z; Nilsson, G; Kleinau, S

Part of Scand J Immunol, p. 282-9, 2006

Gene targeting by ribozyme against TNF-alpha mRNA inhibits autoimmune arthritis.

Kumar, R; Dammai, V; Yadava, P K; Kleinau, S

Part of Gene Ther, p. 1486-93, 2005

IgG Fc receptor polymorphisms and association with autoimmune disease.

Andrén, Maria; Johanneson, Bo; Alarcon Riquelme, Marta E; Kleinau, Sandra

Part of Eur J Immunol, p. 3020-9, 2005

Induction of arthritis by single monoclonal IgG anti-collagen type II antibodies and enhancement of arthritis in mice lacking inhibitory FcgammaRIIB.

Nandakumar, Kutty Selva; Andrén, Maria; Martinsson, Pernilla; Bajtner, Estelle et al.

Part of Eur J Immunol, p. 2269-77, 2003

Activated mast cells promote a pro-inflammatory phenotype of B cells

Palm, Anna-Karin E.; Garcia Faroldi, Gianni; Lundberg, Marcus; Pejler, Gunnar et al.

The impact of Fc receptors on the development of autoimmune diseases.

Kleinau, S

Part of Curr Pharm Des, p. 1861-70, 2003

Human problems - animal models: Aspects on the use of inducible experimental arthritis for pathogenetic studies of human inflammatory joint disease

Klareskog, L; Kleinau, S; Ulfgren, A; Mussener, Å et al.

Part of Rheumatology Highligths 95 Rheumatology in Europe, p. 8, 1995