Mia Wadelius

HLA-B*44 Alleles and HLA-DQA1*03:01 as Genetic Risk Factors for Drug-Induced Liver Injury due to Fluoroquinolones

Nicoletti, Paola; Lucena, M. Isabel; Andrade, Raul J.; Zafer, Samreen et al.

Part of Liver international, 2026

• DOI for HLA-B*44 Alleles and HLA-DQA1*03:01 as Genetic Risk Factors for Drug-Induced Liver Injury due to Fluoroquinolones
• Download full text (pdf) of HLA-B*44 Alleles and HLA-DQA1*03:01 as Genetic Risk Factors for Drug-Induced Liver Injury due to Fluoroquinolones

The 8th European Society of Pharmacogenomics and Personalized Therapy (ESPT) congress

van Schaik, Ron H. N.; Swen, Jesse J.; Llerena, Adrian; Koch, Birgit C. P. et al.

Part of Pharmacogenomics (London), p. 5-8, 2026

• DOI for The 8th European Society of Pharmacogenomics and Personalized Therapy (ESPT) congress

Risk of venous thromboembolism after SARS-CoV-2 vaccination - evidence from genome-wide association study and population-based observational study

Attelind, Sofia; Eriksson, Niclas; Cavalli, Marco; Xu, Yiyi et al.

2026

Genome-wide association study of direct oral anticoagulants and their relation to bleeding

Attelind, Sofia; Eriksson, Niclas; Wadelius, Mia; Hallberg, Pär

Part of European Journal of Clinical Pharmacology, p. 771-783, 2025

• DOI for Genome-wide association study of direct oral anticoagulants and their relation to bleeding
• Download full text (pdf) of Genome-wide association study of direct oral anticoagulants and their relation to bleeding

Response commentary: genome-wide association study of direct oral anticoagulants and their relation to bleeding

Attelind, Sofia; Eriksson, Niclas; Wadelius, Mia; Hallberg, Pär

Part of European Journal of Clinical Pharmacology, p. 1373-1373, 2025

• DOI for Response commentary: genome-wide association study of direct oral anticoagulants and their relation to bleeding

HLA-B*44 Alleles and HLA-DQA1*03:01 as Genetic Risk Factors for Drug-Induced Liver Injury due to Fluoroquinolones

Nicoletti, Paola; Lucena, M. Isabel; Andrade, Raul J.; Zafer, Samreen et al.

Part of Liver international, 2026

• DOI for HLA-B*44 Alleles and HLA-DQA1*03:01 as Genetic Risk Factors for Drug-Induced Liver Injury due to Fluoroquinolones
• Download full text (pdf) of HLA-B*44 Alleles and HLA-DQA1*03:01 as Genetic Risk Factors for Drug-Induced Liver Injury due to Fluoroquinolones

The 8th European Society of Pharmacogenomics and Personalized Therapy (ESPT) congress

van Schaik, Ron H. N.; Swen, Jesse J.; Llerena, Adrian; Koch, Birgit C. P. et al.

Part of Pharmacogenomics (London), p. 5-8, 2026

• DOI for The 8th European Society of Pharmacogenomics and Personalized Therapy (ESPT) congress

Genome-wide association study of direct oral anticoagulants and their relation to bleeding

Attelind, Sofia; Eriksson, Niclas; Wadelius, Mia; Hallberg, Pär

Part of European Journal of Clinical Pharmacology, p. 771-783, 2025

• DOI for Genome-wide association study of direct oral anticoagulants and their relation to bleeding
• Download full text (pdf) of Genome-wide association study of direct oral anticoagulants and their relation to bleeding

Response commentary: genome-wide association study of direct oral anticoagulants and their relation to bleeding

Attelind, Sofia; Eriksson, Niclas; Wadelius, Mia; Hallberg, Pär

Part of European Journal of Clinical Pharmacology, p. 1373-1373, 2025

• DOI for Response commentary: genome-wide association study of direct oral anticoagulants and their relation to bleeding

Evaluating IL1RA-Autoantibodies Across SARS-CoV-2-Related Diseases

Behere, Anish; Hallberg, Pär; Cederholm, Axel; Cavalli, Marco et al.

Part of Scandinavian Journal of Immunology, 2025

• DOI for Evaluating IL1RA-Autoantibodies Across SARS-CoV-2-Related Diseases
• Download full text (pdf) of Evaluating IL1RA-Autoantibodies Across SARS-CoV-2-Related Diseases

Genome-wide association study of myocarditis and pericarditis following COVID-19 vaccination

Cavalli, Marco; Eriksson, Niclas; Baron, Tomasz; Yalcinkaya, Ahmet et al.

Part of npj Vaccines, 2025

• DOI for Genome-wide association study of myocarditis and pericarditis following COVID-19 vaccination
• Download full text (pdf) of Genome-wide association study of myocarditis and pericarditis following COVID-19 vaccination

No link between type I interferon autoantibody positivity and adverse reactions to COVID-19 vaccines

Yalcinkaya, Ahmet; Cavalli, Marco; Cederholm, Axel; Aranda-Guillen, Maribel et al.

Part of npj Vaccines, 2024

• DOI for No link between type I interferon autoantibody positivity and adverse reactions to COVID-19 vaccines
• Download full text (pdf) of No link between type I interferon autoantibody positivity and adverse reactions to COVID-19 vaccines

Meta-analysis of ACE inhibitor-induced angioedema identifies novel risk locus

Mathey, Carina M.; Maj, Carlo; Eriksson, Niclas; Krebs, Kristi et al.

Part of Journal of Allergy and Clinical Immunology, p. 1073-1082, 2024

• DOI for Meta-analysis of ACE inhibitor-induced angioedema identifies novel risk locus
• Download full text (pdf) of Meta-analysis of ACE inhibitor-induced angioedema identifies novel risk locus

Precision Diagnostics in Myeloid Malignancies: Development and Validation of a National Capture‐Based Gene Panel

Orsmark‐Pietras, Christina; Lyander, Anna; Ladenvall, Claes; Hallström, Björn et al.

Part of Genes, Chromosomes and Cancer, 2024

• DOI for Precision Diagnostics in Myeloid Malignancies: Development and Validation of a National Capture‐Based Gene Panel
• Download full text (pdf) of Precision Diagnostics in Myeloid Malignancies: Development and Validation of a National Capture‐Based Gene Panel

Autoantibodies to protein S may explain rare cases of coagulopathy following COVID-19 vaccination

Yalcinkaya, Ahmet; Cavalli, Marco; Aranda-Guillén, Maribel; Cederholm, Axel et al.

Part of Scientific Reports, 2024

• DOI for Autoantibodies to protein S may explain rare cases of coagulopathy following COVID-19 vaccination
• Download full text (pdf) of Autoantibodies to protein S may explain rare cases of coagulopathy following COVID-19 vaccination

Gene-based association analysis of a large patient cohort provides insights into genetics of atypical femur fractures

Zhou, Wei; Ås, Joel; Shore-Lorenti, Catherine; Nguyen, Hanh H. et al.

Part of Journal of Bone and Mineral Research, p. 1315-1326, 2024

• DOI for Gene-based association analysis of a large patient cohort provides insights into genetics of atypical femur fractures
• Download full text (pdf) of Gene-based association analysis of a large patient cohort provides insights into genetics of atypical femur fractures

Identification of risk factors for adverse drug reactions in a pharmacovigilance database

Attelind, Sofia; Eriksson, Niclas; Sundstroem, A.; Wadelius, Mia et al.

Part of Pharmacoepidemiology and Drug Safety, 2024

• DOI for Identification of risk factors for adverse drug reactions in a pharmacovigilance database

Whole genome case-control study of central nervous system toxicity due to antimicrobial drugs

Ås, Joel; Bertulyte, Ilma; Norgren, Nina; Johansson, Anna et al.

Part of PLOS ONE, 2024

• DOI for Whole genome case-control study of central nervous system toxicity due to antimicrobial drugs
• Download full text (pdf) of Whole genome case-control study of central nervous system toxicity due to antimicrobial drugs

Identification of risk factors for adverse drug reactions in a pharmacovigilance database

Attelind, Sofia; Eriksson, Niclas; Sundström, Anders; Wadelius, Mia et al.

Part of Pharmacoepidemiology and Drug Safety, p. 1431-1438, 2023

• DOI for Identification of risk factors for adverse drug reactions in a pharmacovigilance database
• Download full text (pdf) of Identification of risk factors for adverse drug reactions in a pharmacovigilance database

Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy

Ollila, Hanna M.; Sharon, Eilon; Lin, Ling; Sinnott-Armstrong, Nasa et al.

Part of Nature Communications, 2023

• DOI for Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy
• Download full text (pdf) of Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy

Genetic determinants of apixaban plasma levels and their relationship to bleeding and thromboembolic events

Attelind, Sofia; Hallberg, Pär; Wadelius, Mia; Hamberg, Anna-Karin et al.

Part of Frontiers in Genetics, 2022

• DOI for Genetic determinants of apixaban plasma levels and their relationship to bleeding and thromboembolic events
• Download full text (pdf) of Genetic determinants of apixaban plasma levels and their relationship to bleeding and thromboembolic events

Genome-wide association study of liver enzyme elevation in an extended cohort of rheumatoid arthritis patients starting low-dose methotrexate

Cavalli, Marco; Eriksson, Niclas; Karlsson Sundbaum, Johanna; Wallenberg, Matilda et al.

Part of Pharmacogenomics (London), p. 813-820, 2022

• DOI for Genome-wide association study of liver enzyme elevation in an extended cohort of rheumatoid arthritis patients starting low-dose methotrexate
• Download full text (pdf) of Genome-wide association study of liver enzyme elevation in an extended cohort of rheumatoid arthritis patients starting low-dose methotrexate

HLA variants associated with azathioprine-induced pancreatitis in patients with Crohn's disease

Ås, Joel; Bertulyte, Ilma; Eriksson, Niclas; Magnusson, Patrik K. E. et al.

Part of Clinical and Translational Science, p. 1249-1256, 2022

• DOI for HLA variants associated with azathioprine-induced pancreatitis in patients with Crohn's disease
• Download full text (pdf) of HLA variants associated with azathioprine-induced pancreatitis in patients with Crohn's disease

Implementing precision medicine in a regionally organized healthcare system in Sweden.

Fioretos, Thoas; Wirta, Valtteri; Cavelier, Lucia; Berglund, Eva et al.

Part of Nature Medicine, p. 1980-1982, 2022

• DOI for Implementing precision medicine in a regionally organized healthcare system in Sweden.

Molecular Genetic Screening in Patients With ACE Inhibitor/Angiotensin Receptor Blocker-Induced Angioedema to Explore the Role of Hereditary Angioedema Genes

Mathey, Carina M; Maj, Carlo; Scheer, Annika B; Fazaal, Julia et al.

Part of Frontiers in Genetics, 2022

• DOI for Molecular Genetic Screening in Patients With ACE Inhibitor/Angiotensin Receptor Blocker-Induced Angioedema to Explore the Role of Hereditary Angioedema Genes
• Download full text (pdf) of Molecular Genetic Screening in Patients With ACE Inhibitor/Angiotensin Receptor Blocker-Induced Angioedema to Explore the Role of Hereditary Angioedema Genes

The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1, ABCG2, and CYP2C9 genotypes and Statin-Associated Musculoskeletal Symptoms

Cooper-DeHoff, Rhonda M.; Niemi, Mikko; Ramsey, Laura B.; Luzum, Jasmine A. et al.

Part of Clinical Pharmacology and Therapeutics, p. 1007-1021, 2022

• DOI for The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1, ABCG2, and CYP2C9 genotypes and Statin-Associated Musculoskeletal Symptoms

Genome-wide association study of liver enzyme elevation in rheumatoid arthritis patients starting methotrexate

Karlsson Sundbaum, Johanna; Baecklund, Eva; Eriksson, Niclas; Kohnke, Hugo et al.

Part of Pharmacogenomics (London), p. 973-982, 2021

• DOI for Genome-wide association study of liver enzyme elevation in rheumatoid arthritis patients starting methotrexate
• Download full text (pdf) of Genome-wide association study of liver enzyme elevation in rheumatoid arthritis patients starting methotrexate

Pharmacogenetics of angiotensin-converting enzyme inhibitor-induced angioedema

Pall, Amalie Hartvig; Rasmussen, Eva Rye; Wadelius, Mia

Part of Pharmacogenomics (London), p. 319-321, 2021

• DOI for Pharmacogenetics of angiotensin-converting enzyme inhibitor-induced angioedema

Association of Variants Near the Bradykinin Receptor B2 Gene With Angioedema in Patients Taking ACE Inhibitors

Ghouse, Jonas; Ahlberg, Gustav; Andreasen, Laura; Banasi, Karina et al.

Part of Journal of the American College of Cardiology, p. 696-709, 2021

• DOI for Association of Variants Near the Bradykinin Receptor B2 Gene With Angioedema in Patients Taking ACE Inhibitors

Fördelaktigt med genetisk analys före behandling med 5-fluorouracil: Utvärdering tyder på mindre biverkningar och kostnadsbesparing för sjukvården: [New recommendation on pharmacogenetic screening prior to 5-fluorouracil based cancer treatment - Swedish experience indicates less adverse effects and healthcare cost savings]

Schultz, Alice; Kohnke, Hugo; Wadelius, Mia; Nygren, Peter

Part of Läkartidningen, 2021

PharmVar GeneFocus: CYP2C9

Sangkuhl, Katrin; Claudio-Campos, Karla; Cavallari, Larisa H; Agundez, Jose A G et al.

Part of Clinical Pharmacology and Therapeutics, p. 662-676, 2021

• DOI for PharmVar GeneFocus: CYP2C9
• Download full text (pdf) of PharmVar GeneFocus: CYP2C9

Genetic Risk Factors in Drug-Induced Liver Injury Due to Isoniazid-Containing Antituberculosis Drug Regimens

Nicoletti, Paola; Devarbhavi, Harshad; Goel, Ashish; Venkatesan, Radha et al.

Part of Clinical Pharmacology and Therapeutics, p. 1125-1135, 2021

• DOI for Genetic Risk Factors in Drug-Induced Liver Injury Due to Isoniazid-Containing Antituberculosis Drug Regimens
• Download full text (pdf) of Genetic Risk Factors in Drug-Induced Liver Injury Due to Isoniazid-Containing Antituberculosis Drug Regimens

Exome sequencing reveals common and rare variants in F5 associated with ACE inhibitor and angiotensin receptor blocker-induced angioedema

Maroteau, Cyrielle; Siddiqui, Moneeza Kalhan; Veluchamy, Abirami; Carr, Fiona et al.

Part of Clinical Pharmacology and Therapeutics, p. 1195-1202, 2020

• DOI for Exome sequencing reveals common and rare variants in F5 associated with ACE inhibitor and angiotensin receptor blocker-induced angioedema
• Download full text (pdf) of Exome sequencing reveals common and rare variants in F5 associated with ACE inhibitor and angiotensin receptor blocker-induced angioedema

Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment.

Rasmussen, Eva Rye; Hallberg, Pär; Baranova, Ekaterina V; Eriksson, Niclas et al.

Part of The Pharmacogenomics Journal, p. 770-783, 2020

• DOI for Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment.
• Download full text (pdf) of Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment.

Genome-Wide Association Study of Metamizole-Induced Agranulocytosis in European Populations

Cismaru, Anca Liliana; Rudin, Deborah; Ibanez, Luisa; Liakoni, Evangelia et al.

Part of Genes, 2020

• DOI for Genome-Wide Association Study of Metamizole-Induced Agranulocytosis in European Populations
• Download full text (pdf) of Genome-Wide Association Study of Metamizole-Induced Agranulocytosis in European Populations

High-Throughput Sequencing to Investigate Associations Between HLA Genes and Metamizole-Induced Agranulocytosis

Cismaru, Anca Liliana; Grimm, Livia; Rudin, Deborah; Ibanez, Luisa et al.

Part of Frontiers in Genetics, 2020

• DOI for High-Throughput Sequencing to Investigate Associations Between HLA Genes and Metamizole-Induced Agranulocytosis
• Download full text (pdf) of High-Throughput Sequencing to Investigate Associations Between HLA Genes and Metamizole-Induced Agranulocytosis

SWEDEGENE: a Swedish nation-wide DNA sample collection for pharmacogenomic studies of serious adverse drug reactions

Hallberg, Pär; Yue, Qun-Ying; Eliasson, Erik; Melhus, Håkan et al.

Part of The Pharmacogenomics Journal, p. 579-585, 2020

• DOI for SWEDEGENE: a Swedish nation-wide DNA sample collection for pharmacogenomic studies of serious adverse drug reactions
• Download full text (pdf) of SWEDEGENE: a Swedish nation-wide DNA sample collection for pharmacogenomic studies of serious adverse drug reactions

MTHFR, TYMS and SLCO1B1 polymorphisms and adverse liver effects of methotrexate in rheumatoid arthritis

Karlsson Sundbaum, Johanna; Baecklund, Eva; Eriksson, Niclas; Hallberg, Pär et al.

Part of Pharmacogenomics (London), p. 337-346, 2020

• DOI for MTHFR, TYMS and SLCO1B1 polymorphisms and adverse liver effects of methotrexate in rheumatoid arthritis

Methotrexate treatment in rheumatoid arthritis and elevated liver enzymes: A long-term follow-up of predictors, surveillance, and outcome in clinical practice

Karlsson Sundbaum, Johanna; Eriksson, Niclas; Hallberg, Pär; Lehto, Niklas et al.

Part of INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, p. 1226-1232, 2019

• DOI for Methotrexate treatment in rheumatoid arthritis and elevated liver enzymes: A long-term follow-up of predictors, surveillance, and outcome in clinical practice
• Download full text (pdf) of Methotrexate treatment in rheumatoid arthritis and elevated liver enzymes: A long-term follow-up of predictors, surveillance, and outcome in clinical practice

Drug-Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles

Nicoletti, Paola; Aithal, Guruprasad P.; Chamberlain, Thomas C.; Coulthard, Sally et al.

Part of Clinical Pharmacology and Therapeutics, p. 245-253, 2019

• DOI for Drug-Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles

A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury

Cirulli, Elizabeth T.; Nicoletti, Paola; Abramson, Karen; Andrade, Raul J. et al.

Part of Gastroenterology, p. 1707-1716, 2019

• DOI for A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury

Shared Genetic Risk Factors Across Carbamazepine-Induced Hypersensitivity Reactions

Nicoletti, Paola; Barrett, Sarah; McEvoy, Laurence; Daly, Ann K. et al.

Part of Clinical Pharmacology and Therapeutics, p. 1028-1036, 2019

• DOI for Shared Genetic Risk Factors Across Carbamazepine-Induced Hypersensitivity Reactions
• Download full text (pdf) of Shared Genetic Risk Factors Across Carbamazepine-Induced Hypersensitivity Reactions

Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing

Floyd, James S.; Bloch, Katarzyna M.; Brody, Jennifer A.; Maroteau, Cyrielle et al.

Part of PLOS ONE, 2019

• DOI for Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing
• Download full text (pdf) of Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing

Pandemrix-induced narcolepsy is associated with genes related to immunity and neuronal survival

Hallberg, Pär; Smedje, Hans; Eriksson, Niclas; Kohnke, Hugo et al.

Part of EBioMedicine, p. 595-604, 2019

• DOI for Pandemrix-induced narcolepsy is associated with genes related to immunity and neuronal survival
• Download full text (pdf) of Pandemrix-induced narcolepsy is associated with genes related to immunity and neuronal survival

A Genome-Wide Association Study of Bisphosphonate-Associated Atypical Femoral Fracture

Kharazmi, Mohammad; Michaëlsson, Karl; Schilcher, Jorg; Eriksson, Niclas et al.

Part of Calcified Tissue International, p. 51-67, 2019

• DOI for A Genome-Wide Association Study of Bisphosphonate-Associated Atypical Femoral Fracture
• Download full text (pdf) of A Genome-Wide Association Study of Bisphosphonate-Associated Atypical Femoral Fracture

Methotrexate treatment in rheumatoid arthritis and elevated liver enzymes: a long-term follow-up of occurrence, predictors, surveillance, and outcome in clinical practice

Sundbaum, J. K.; Ericsson, N.; Hallberg, Pär; Lehto, N. et al.

Part of Annals of the Rheumatic Diseases, p. 977-977, 2018

• DOI for Methotrexate treatment in rheumatoid arthritis and elevated liver enzymes: a long-term follow-up of occurrence, predictors, surveillance, and outcome in clinical practice

Clinical factors predicting drug-induced liver injury due to flucloxacillin

Lindh, Mikaela; Hallberg, Pär; Yue, Qun-Ying; Wadelius, Mia

Part of Drug, Healthcare and Patient Safety, p. 95-101, 2018

• DOI for Clinical factors predicting drug-induced liver injury due to flucloxacillin
• Download full text (pdf) of Clinical factors predicting drug-induced liver injury due to flucloxacillin

Common variation near IRF6 is associated with IFN-beta-induced liver injury in multiple sclerosis

Kowalec, Kaarina; Wright, Galen E. B.; Drogemoller, Britt I.; Aminkeng, Folefac et al.

Part of Nature Genetics, p. 1081-+, 2018

• DOI for Common variation near IRF6 is associated with IFN-beta-induced liver injury in multiple sclerosis

Fusidic Acid: A Neglected Risk Factor for Statin-Associated Myopathy

Rönnqvist, Josefine; Hallberg, Pär; Yue, Qun-Ying; Wadelius, Mia

Part of Clinical Medicine Insights, 2018

• DOI for Fusidic Acid: A Neglected Risk Factor for Statin-Associated Myopathy
• Download full text (pdf) of Fusidic Acid: A Neglected Risk Factor for Statin-Associated Myopathy

Sulfasalazine-Induced Agranulocytosis Is Associated With the Human Leukocyte Antigen Locus.

Wadelius, Mia; Eriksson, Niclas; Kreutz, Reinhold; Bondon-Guitton, Emmanuelle et al.

Part of Clinical Pharmacology and Therapeutics, p. 843-853, 2018

• DOI for Sulfasalazine-Induced Agranulocytosis Is Associated With the Human Leukocyte Antigen Locus.
• Download full text (pdf) of Sulfasalazine-Induced Agranulocytosis Is Associated With the Human Leukocyte Antigen Locus.

Assessment of 105 patients with angiotensin converting enzyme-inhibitor induced angioedema eva

Rasmussen, E. R.; Buchwald, C. ; Wadelius, Mia; Prasad, S. C. et al.

Part of Allergy. European Journal of Allergy and Clinical Immunology, p. 415-415, 2018

• DOI for Assessment of 105 patients with angiotensin converting enzyme-inhibitor induced angioedema eva

Genome‐Wide Association Study of Pandemrix‐Induced Narcolepsy in Sweden – A Possible Role for Glial Derived Neurotrophic Factor (GDNF)

Wadelius, Mia; Eriksson, Niclas; Smedje, H.; Yue, Q. -Y et al.

Part of Basic & Clinical Pharmacology & Toxicology, p. 12-13, 2018

• DOI for Genome‐Wide Association Study of Pandemrix‐Induced Narcolepsy in Sweden – A Possible Role for Glial Derived Neurotrophic Factor (GDNF)

Effect of CYP2C9, VKORC1, and CYP4F2 on warfarin maintenance dose in children aged less than 18 year of age: systematic review and meta-analysis

Takeuchi, M.; Kobayashi, T.; Biss, T.; Kamali, F. et al.

Part of Clinical Pharmacology and Therapeutics, 2018

• DOI for Effect of CYP2C9, VKORC1, and CYP4F2 on warfarin maintenance dose in children aged less than 18 year of age: systematic review and meta-analysis

Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study

Nicoletti, Paola; Aithal, Guruprasad P.; Bjornsson, Einar S.; Andrade, Raul J. et al.

Part of Gastroenterology, p. 1078-1089, 2017

• DOI for Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study

Multiple HLA B*57 alleles, sharing the amino acid residue Valine(97), are associated with drug-induced liver injury due to flucloxacillin in a European population.

Nicoletti, Paola; Aithal, Guruprasad P.; Coulthard, Sally; Andrade, Raul et al.

Part of Hepatology, 2017

A common missense variant of LILRB5 is associated with statin intolerance and myalgia

Siddiqui, Moneeza K.; Maroteau, Cyrielle; Veluchamy, Abirami; Tornio, Aleksi et al.

Part of European Heart Journal, p. 3569-U31, 2017

• DOI for A common missense variant of LILRB5 is associated with statin intolerance and myalgia
• Download full text (pdf) of A common missense variant of LILRB5 is associated with statin intolerance and myalgia

Cohort-specific imputation of gene expression improves prediction of warfarin dose for African Americans

Gottlieb, Assaf; Daneshjou, Roxana; DeGorter, M; Bourgeois, S et al.

Part of Genome Medicine, 2017

• DOI for Cohort-specific imputation of gene expression improves prediction of warfarin dose for African Americans
• Download full text (pdf) of Cohort-specific imputation of gene expression improves prediction of warfarin dose for African Americans

CKM Glu83Gly Is Associated With Blunted Creatine Kinase Variation, but Not With Myalgia

Siddiqui, Moneeza Kalhan; Veluchamy, Abirami; Maroteau, Cyrielle; Tavendale, Roger et al.

Part of Circulation, 2017

• DOI for CKM Glu83Gly Is Associated With Blunted Creatine Kinase Variation, but Not With Myalgia

Preventivt arbete kan minska läkemedelsbiverkningar

Hallberg, Pär; Collin, Sofie; Wadelius, Mia

Part of Läkartidningen, 2017

Whole exome sequencing in individuals with statin-induced myopathy

Bloch, K. M.; Carr, D.; Pirmohamed, M.; Morris, A. et al.

Part of Drug Safety, p. 1026-1026, 2017

Assessment of 105 Patients with Angiotensin Converting Enzyme-Inhibitor Induced Angioedema

Rasmussen, Eva Rye; von Buchwald, Christian; Wadelius, Mia; Prasad, Sumangali Chandra et al.

Part of International Journal of Otolaryngology, 2017

• DOI for Assessment of 105 Patients with Angiotensin Converting Enzyme-Inhibitor Induced Angioedema
• Download full text (pdf) of Assessment of 105 Patients with Angiotensin Converting Enzyme-Inhibitor Induced Angioedema

Comparison of Clinical Factors Between Patients With Angiotensin-Converting Enzyme Inhibitor-Induced Angioedema and Cough

Hallberg, Pär; Nagy, Julia; Karawajczyk, Malgorzata; Nordang, Leif et al.

Part of The Annals of Pharmacotherapy, p. 293-300, 2017

• DOI for Comparison of Clinical Factors Between Patients With Angiotensin-Converting Enzyme Inhibitor-Induced Angioedema and Cough

Genetic variants associated with angiotensin-converting enzyme inhibitor-induced cough: a genome-wide association study in a Swedish population

Hallberg, Pär; Persson, Matilda; Axelsson, Tomas; Cavalli, Marco et al.

Part of Pharmacogenomics (London), p. 201-213, 2017

• DOI for Genetic variants associated with angiotensin-converting enzyme inhibitor-induced cough: a genome-wide association study in a Swedish population
• Download full text (pdf) of Genetic variants associated with angiotensin-converting enzyme inhibitor-induced cough: a genome-wide association study in a Swedish population

Time to onset of bisphosphonate-related osteonecrosis of the jaws: a multicentre retrospective cohort study

Fung, P. P. L.; Bedogni, G.; Bedogni, A.; Petrie, A. et al.

Part of Oral Diseases, p. 477-483, 2017

• DOI for Time to onset of bisphosphonate-related osteonecrosis of the jaws: a multicentre retrospective cohort study

Genome-wide scan identifies association between an interferon regulatory factor-related variant and interferon-beta induced liver injury in multiple sclerosis patients

Kowalec, K.; Wright, G. E. B.; Drogemoller, B. I.; Aminkeng, F. et al.

Part of Multiple Sclerosis Journal, p. 834-836, 2016

Novel regulatory variant detected on the VKORC1 haplotype that is associated with warfarin dose

Cavalli, Marco; Pan, Gang; Nord, Helena; Eriksson, Niclas et al.

Part of Pharmacogenomics (London), p. 1305-1314, 2016

• DOI for Novel regulatory variant detected on the VKORC1 haplotype that is associated with warfarin dose
• Download full text (pdf) of Novel regulatory variant detected on the VKORC1 haplotype that is associated with warfarin dose

Genetic determinants of warfarin maintenance dose and time in therapeutic treatment range: a RE-LY genomics substudy

Eriksson, Niclas; Wallentin, Lars; Berglund, Lars; Axelsson, Tomas et al.

Part of Pharmacogenomics (London), p. 1425-1439, 2016

• DOI for Genetic determinants of warfarin maintenance dose and time in therapeutic treatment range: a RE-LY genomics substudy
• Download full text (pdf) of Genetic determinants of warfarin maintenance dose and time in therapeutic treatment range: a RE-LY genomics substudy

Cost-effectiveness of pharmacogenetic-guided dosing of warfarin in the United Kingdom and Sweden

Verhoef, T. I.; Redekop, W. K.; Langenskiöld, Sophie; Kamali, F. et al.

Part of The Pharmacogenomics Journal, p. 478-484, 2016

• DOI for Cost-effectiveness of pharmacogenetic-guided dosing of warfarin in the United Kingdom and Sweden

Genetic variants associated with antithyroid drug-induced agranulocytosis: a genome-wide association study in a European population

Hallberg, Pär; Eriksson, Niclas; Ibanez, Luisa; Bondon-Guitton, Emmanuelle et al.

Part of The Lancet Diabetes and Endocrinology, p. 507-516, 2016

• DOI for Genetic variants associated with antithyroid drug-induced agranulocytosis: a genome-wide association study in a European population

A Bayesian decision support tool for efficient dose individualization of warfarin in adults and children

Hamberg, Anna-Karin; Hellman, Jacob; Dahlberg, Jonny; Jonsson, E Niclas et al.

Part of BMC Medical Informatics and Decision Making, 2015

• DOI for A Bayesian decision support tool for efficient dose individualization of warfarin in adults and children
• Download full text (pdf) of A Bayesian decision support tool for efficient dose individualization of warfarin in adults and children

Genome-wide association study of warfarin maintenance dose in a Brazilian sample

Parra, Esteban J.; Botton, Mariana R.; Perini, Jamila A.; Krithika, S. et al.

Part of Pharmacogenomics (London), p. 1253-1263, 2015

• DOI for Genome-wide association study of warfarin maintenance dose in a Brazilian sample

Quality of life in patients with venous thromboembolism and atrial fibrillation treated with coumarin anticoagulants

Marvig, Camilla L.; Verhoef, Talitha I.; de Boer, Anthonius; Kamali, Farhad et al.

Part of Thrombosis Research, p. 69-75, 2015

• DOI for Quality of life in patients with venous thromboembolism and atrial fibrillation treated with coumarin anticoagulants

Genetic Markers of Toxicity From Capecitabine and Other Fluorouracil-Based Regimens: Investigation in the QUASAR2 Study, Systematic Review, and Meta-Analysis

Rosmarin, Dan; Palles, Claire; Church, David; Domingo, Enric et al.

Part of Journal of Clinical Oncology, p. 1031-1039, 2014

• DOI for Genetic Markers of Toxicity From Capecitabine and Other Fluorouracil-Based Regimens: Investigation in the QUASAR2 Study, Systematic Review, and Meta-Analysis

Patients Benefit From Genetics-Guided Coumarin Anticoagulant Therapy

Maitland-van der Zee, A. H.; Daly, A. K.; Kamali, F.; Manolopoulous, V. G. et al.

Part of Clinical Pharmacology and Therapeutics, p. 15-17, 2014

• DOI for Patients Benefit From Genetics-Guided Coumarin Anticoagulant Therapy

The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1 and Simvastatin-Induced Myopathy: 2014 Update

Ramsey, L. B.; Johnson, S. G.; Caudle, K. E.; Haidar, C. E. et al.

Part of Clinical Pharmacology and Therapeutics, p. 423-428, 2014

• DOI for The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1 and Simvastatin-Induced Myopathy: 2014 Update

Genotype-Guided Dosing of Vitamin K Antagonists REPLY

Pirmohamed, Munir; Wadelius, Mia; Kamali, Farhad

Part of New England Journal of Medicine, p. 1764-1765, 2014

The effect of the UGT1A1*28 allele on survival after irinotecan-based chemotherapy: a collaborative meta-analysis

Dias, M M; Pignon, J-P; Karapetis, C S; Boige, V et al.

Part of The Pharmacogenomics Journal, p. 424-431, 2014

• DOI for The effect of the UGT1A1*28 allele on survival after irinotecan-based chemotherapy: a collaborative meta-analysis

Incorporation of Pharmacogenomics into Routine Clinical Practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline Development Process

Caudle, Kelly E; Klein, Teri E; Hoffman, James M; Muller, Daniel J et al.

Part of Current drug metabolism, p. 209-217, 2014

• DOI for Incorporation of Pharmacogenomics into Routine Clinical Practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline Development Process

Warfarin pharmacogenetics: it matters if you're black or white

Wadelius, Mia

Part of Blood, p. 2171-2171, 2014

• DOI for Warfarin pharmacogenetics: it matters if you're black or white

Waran doseras bättre efter genanalys

Wadelius, Mia; Eriksson, Niclas

Part of Läkartidningen, p. 22-22, 2014

Characterising variability in warfarin dose requirements in children using modelling and simulation

Hamberg, Anna-Karin; Wadelius, Mia; Friberg, Lena E; Biss, Tina T et al.

Part of British Journal of Clinical Pharmacology, p. 158-169, 2013

• DOI for Characterising variability in warfarin dose requirements in children using modelling and simulation

A Randomized Trial of Genotype-Guided Dosing of Warfarin

Pirmohamed, Munir; Burnside, Girvan; Eriksson, Niclas; Jorgensen, Andrea L. et al.

Part of New England Journal of Medicine, p. 2294-2303, 2013

• DOI for A Randomized Trial of Genotype-Guided Dosing of Warfarin

A Randomized Trial of Genotype-Guided Dosing of Acenocoumarol and Phenprocoumon

Verhoef, Talitha I.; Ragia, Georgia; de Boer, Anthonius; Barallon, Rita et al.

Part of New England Journal of Medicine, p. 2304-2312, 2013

• DOI for A Randomized Trial of Genotype-Guided Dosing of Acenocoumarol and Phenprocoumon

A Randomized Trial Comparing Genotype-Guided Dosing of Warfarin to Standard Dosing: The EU Pharmacogenetics of Anticoagulant Therapy (EU-PACT) Warfarin Study

Pirmohamed, Munir; Burnside, Girvan; Stoddern, Jenni; Prince, Clare et al.

Part of Circulation, p. 2710-2711, 2013

• DOI for A Randomized Trial Comparing Genotype-Guided Dosing of Warfarin to Standard Dosing: The EU Pharmacogenetics of Anticoagulant Therapy (EU-PACT) Warfarin Study

Warfarin dose prediction in children using pharmacometric bridging: comparison with published pharmacogenetic dosing algorithms

Hamberg, Anna-Karin; Friberg, Lena E; Hanséus, Katarina; Ekman-Joelsson, Britt-Marie et al.

Part of European Journal of Clinical Pharmacology, p. 1275-1283, 2013

• DOI for Warfarin dose prediction in children using pharmacometric bridging: comparison with published pharmacogenetic dosing algorithms
• Download full text (pdf) of Warfarin dose prediction in children using pharmacometric bridging: comparison with published pharmacogenetic dosing algorithms

Genetic Determinants of Dabigatran Plasma Levels and Their Relation to Bleeding

Paré, Guillaume; Eriksson, Niclas; Lehr, Thorsten; Connolly, Stuart et al.

Part of Circulation, p. 1404, 2013

• DOI for Genetic Determinants of Dabigatran Plasma Levels and Their Relation to Bleeding

Expression Quantitative Trait Loci Analysis of Stable Warfarin Dose Identifies Novel Associations: Finding Signal within the Noise

Gamazon, E. R.; Daneshjou, R.; Cavallari, L. H.; Limdi, N. A. et al.

Part of Clinical Pharmacology and Therapeutics, 2013

Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study

Perera, Minoli A.; Cavallari, Larisa H.; Limdi, Nita A.; Gamazon, Eric R. et al.

Part of The Lancet, p. 790-796, 2013

• DOI for Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study

Farmakogenetisk analys kan avslöja risk för statinbiverkningar: [Pharmacogenetic analysis can predict adverse effects of statins]

Garwicz, Daniel; Wadelius, Mia

Part of Läkartidningen, p. 951-952, 2013

Pharmacogenetic warfarin dose refinements remain significantly influenced by genetic factors after one week of therapy

Horne, B D; Lenzini, P A; Wadelius, Mia; Jorgensen, A L et al.

Part of Thrombosis and Haemostasis, p. 232-240, 2012

• DOI for Pharmacogenetic warfarin dose refinements remain significantly influenced by genetic factors after one week of therapy

miR-133a regulates Vitamin K 2,3-epoxide reductase complex subunit 1 (VKORC1), a key protein in the Vitamin K cycle

Pérez-Andreu, V.; Teruel, R.; Corral, J.; Roldán, V. et al.

Part of Molecular Medicine, p. 1466-1472, 2012

• DOI for miR-133a regulates Vitamin K 2,3-epoxide reductase complex subunit 1 (VKORC1), a key protein in the Vitamin K cycle

Association of the GGCX (CAA) 16/17 repeat polymorphism with higher warfarin dose requirements in African Americans

Cavallari, Larisa H.; Perera, Minoli; Wadelius, Mia; Deloukas, Panos et al.

Part of Pharmacogenetics & Genomics, p. 152-158, 2012

• DOI for Association of the GGCX (CAA) 16/17 repeat polymorphism with higher warfarin dose requirements in African Americans

The Clinical Pharmacogenomics Implementation Consortium: CPIC Guideline for SLCO1B1 and Simvastatin-Induced Myopathy

Wilke, R. A.; Ramsey, L. B.; Johnson, S. G.; Maxwell, W. D. et al.

Part of Clinical Pharmacology and Therapeutics, p. 112-117, 2012

• DOI for The Clinical Pharmacogenomics Implementation Consortium: CPIC Guideline for SLCO1B1 and Simvastatin-Induced Myopathy

Warfarin dose prediction in children using pharmacogenetics information

Biss, Tina; Hamberg, Anna-Karin; Avery, Peter; Wadelius, Mia et al.

Part of British Journal of Haematology, p. 106-109, 2012

• DOI for Warfarin dose prediction in children using pharmacogenetics information

Pharmacogenomics and personalized medicine: the plunge into next-generation sequencing

Wadelius, Mia; Alfirevic, Ana

Part of Genome Medicine, p. 78, 2011

• DOI for Pharmacogenomics and personalized medicine: the plunge into next-generation sequencing

Prediction of irinotecan and 5-fluorouracil toxicity and response in patients with advanced colorectal cancer

Glimelius, Bengt; Garmo, Hans; Berglund, Åke; Fredriksson, L. A. et al.

Part of The Pharmacogenomics Journal, p. 61-71, 2011

• DOI for Prediction of irinotecan and 5-fluorouracil toxicity and response in patients with advanced colorectal cancer

Genotyping for CYP2C9 and VKORC1 alleles by a novel point of care assay with HyBeacon® probes

Howard, Rebecca; Leathart, Julian B S; French, David J; Krishan, Elaina et al.

Part of Clinica Chimica Acta, p. 2063-2069, 2011

• DOI for Genotyping for CYP2C9 and VKORC1 alleles by a novel point of care assay with HyBeacon® probes

A Proposal for an Individualized Pharmacogenetics-Based Warfarin Initiation Dose Regimen for Patients Commencing Anticoagulation Therapy

Avery, P. J.; Jorgensen, A.; Hamberg, Anna-Karin; Wadelius, Mia et al.

Part of Clinical Pharmacology and Therapeutics, p. 701-706, 2011

• DOI for A Proposal for an Individualized Pharmacogenetics-Based Warfarin Initiation Dose Regimen for Patients Commencing Anticoagulation Therapy

Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across three racial groups

Limdi, Nita A.; Wadelius, Mia; Cavallari, Larissa; Eriksson, Niclas et al.

Part of Blood, p. 3827-3834, 2010

• DOI for Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across three racial groups

A Pharmacometric Model Describing the Relationship Between Warfarin Dose and INR Response With Respect to Variations in CYP2C9, VKORC1, and Age

Hamberg, Anna-Karin; Wadelius, Mia; Lindh, J. D.; Dahl, Marja- Liisa et al.

Part of Clinical Pharmacology and Therapeutics, p. 727-734, 2010

• DOI for A Pharmacometric Model Describing the Relationship Between Warfarin Dose and INR Response With Respect to Variations in CYP2C9, VKORC1, and Age

A systematic review of cost-effectiveness analyses of pharmacogenetic-guided dosing in treatment with coumarin derivatives.

Verhoef, Talitha I; Redekop, William K; Darba, Josep; Geitona, Mary et al.

Part of Pharmacogenomics (London), p. 989-1002, 2010

• DOI for A systematic review of cost-effectiveness analyses of pharmacogenetic-guided dosing in treatment with coumarin derivatives.

Integration of genetic, clinical, and INR data to refine warfarin dosing

Lenzini, P.; Wadelius, Mia; Kimmel, S.; Anderson, J. L. et al.

Part of Clinical Pharmacology and Therapeutics, p. 572-578, 2010

• DOI for Integration of genetic, clinical, and INR data to refine warfarin dosing

A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose

Takeuchi, Fumihiko; McGinnis, Ralph; Bourgeois, Stephane; Eriksson, Niclas et al.

Part of PLoS genetics, 2009

• DOI for A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose

The largest prospective warfarin-treated cohort supports genetic forecasting

Wadelius, Mia; Chen, Leslie Y.; Lindh, Jonatan D.; Eriksson, Niclas et al.

Part of Blood, p. 784-792, 2009

• DOI for The largest prospective warfarin-treated cohort supports genetic forecasting

Rapid Single-Nucleotide Polymorphism Detection of Cytochrome P450 (CYP2C9) and Vitamin K Epoxide Reductase (VKORC1) Genes for the Warfarin Dose Adjustment by the SMart-Amplification Process Version 2

Aomori, Tohru; Yamamoto, Koujirou; Oguchi-Katayama, Atsuko; Kawai, Yuki et al.

Part of Clinical Chemistry, p. 804-812, 2009

• DOI for Rapid Single-Nucleotide Polymorphism Detection of Cytochrome P450 (CYP2C9) and Vitamin K Epoxide Reductase (VKORC1) Genes for the Warfarin Dose Adjustment by the SMart-Amplification Process Version 2

POINT: Use of Pharmacogenetics in Guiding Treatment with Warfarin

Wadelius, Mia

Part of Clinical Chemistry, p. 709-711, 2009

• DOI for POINT: Use of Pharmacogenetics in Guiding Treatment with Warfarin

Genotype-guided dosing of coumarin derivatives: the European pharmacogenetics of anticoagulant therapy (EU-PACT) trial design

van Schie, Rianne M. F.; Wadelius, Mia; Kamali, Farhad; Daly, Ann K. et al.

Part of Pharmacogenomics (London), p. 1687-1695, 2009

• DOI for Genotype-guided dosing of coumarin derivatives: the European pharmacogenetics of anticoagulant therapy (EU-PACT) trial design

Gene polymorphism influencing treatment response in psychotic patients in a naturalistic setting

Alenius, Malin; Wadelius, Mia; Dahl, Marja-Liisa; Hartvig, Per et al.

Part of Journal of Psychiatric Research, p. 884-893, 2008

• DOI for Gene polymorphism influencing treatment response in psychotic patients in a naturalistic setting

Warfarin-noscapine interaction: a series of four case reports

Scordo, Maria Gabriella; Melhus, Håkan; Stjernberg, Elisabet; Edvardsson, Anne Maria et al.

Part of The Annals of Pharmacotherapy, p. 448-450, 2008

• DOI for Warfarin-noscapine interaction: a series of four case reports

Application of a pharmacogenetic-based warfarin dosing algorithm derived from British patients to predict dose in Swedish patients

Hatch, E.; Wynne, H.; Avery, P.; Wadelius, Mia et al.

Part of Journal of Thrombosis and Haemostasis, p. 1038-1040, 2008

• DOI for Application of a pharmacogenetic-based warfarin dosing algorithm derived from British patients to predict dose in Swedish patients

Influence of adenosine triphosphate and ABCB1 (MDR1) genotype on the P-glycoprotein-dependent transfer of saquinavir in the dually perfused human placenta

Rahi, M.; Heikkinen, T.; Hakkola, J.; Hakala, K. et al.

Part of Human and Experimental Toxicology, p. 65-71, 2008

• DOI for Influence of adenosine triphosphate and ABCB1 (MDR1) genotype on the P-glycoprotein-dependent transfer of saquinavir in the dually perfused human placenta

A PK-PD model for predicting the impact of age, CYP2C9, and VKORC1 genotype on individualization of warfarin therapy

Hamberg, Anna Karin; Dahl, Marja-Liisa; Barban, M.; Scordo, Maria Gabriella et al.

Part of Clinical Pharmacology and Therapeutics, p. 529-538, 2007

• DOI for A PK-PD model for predicting the impact of age, CYP2C9, and VKORC1 genotype on individualization of warfarin therapy

Placental transfer of quetiapine in relation to P-glycoprotein activity

Rahi, Melissa; Heikkinen, Tuija; Härtter, Sebastian; Hakkola, Jukka et al.

Part of Journal of Psychopharmacology, p. 751-756, 2007

• DOI for Placental transfer of quetiapine in relation to P-glycoprotein activity

Association of warfarin dose with genes involved in its action and metabolism

Wadelius, Mia; Chen, Leslie Y.; Eriksson, Niclas; Bumpstead, Suzannah et al.

Part of Human Genetics, p. 23-34, 2007

• DOI for Association of warfarin dose with genes involved in its action and metabolism

Possible fluconazole-fentanyl interaction: a case report

Hallberg, Pär; Martén, Leif; Wadelius, Mia

Part of European Journal of Clinical Pharmacology, p. 491-2, 2006

• DOI for Possible fluconazole-fentanyl interaction: a case report

Common VKORC1 and GGCX polymorphisms associated with warfarin dose

Wadelius, Mia; Chen, L.Y.; Downes, K.; Ghori, J. et al.

Part of The Pharmacogenomics Journal, p. 262-70, 2005

• DOI for Common VKORC1 and GGCX polymorphisms associated with warfarin dose

Gamma-glutamyl carboxylase (GGCX) microsatellite and warfarin dosing

Chen, Leslie Y.; Eriksson, Niclas; Gwilliam, Rhian; Bentley, David et al.

Part of Blood, p. 3673-4, 2005

• DOI for Gamma-glutamyl carboxylase (GGCX) microsatellite and warfarin dosing

Functional role of P-glycoprotein in the human blood-placental barrier

Mölsä, Melissa; Heikkinen, Tuija; Hakkola, Jukka; Hakala, Kristo et al.

Part of Clinical Pharmacology and Therapeutics, p. 123-31, 2005

• DOI for Functional role of P-glycoprotein in the human blood-placental barrier

Warfarin dose related to apolipoprotein E (APOE) genotype

Kohnke, Hugo; Sörlin, Kristina; Granath, Göran; Wadelius, Mia

Part of European Journal of Clinical Pharmacology, p. 381-8, 2005

• DOI for Warfarin dose related to apolipoprotein E (APOE) genotype

Apolipoprotein E (APOE) and warfarin dosing in an Italian population

Kohnke, Hugo; Scordo, Gabriella; Pengo, Vittorio; Padrini, Roberto et al.

Part of European Journal of Clinical Pharmacology, p. 781-3, 2005

• DOI for Apolipoprotein E (APOE) and warfarin dosing in an Italian population

Can mutations in ELA2, neutrophil elastase expression or differential cell toxicity explain sulphasalazine-induced agranulocytosis?

Jacobson, Annica; Melhus, Håkan; Wadelius, Mia

Part of BMC Blood Disorders, p. 5, 2004

• DOI for Can mutations in ELA2, neutrophil elastase expression or differential cell toxicity explain sulphasalazine-induced agranulocytosis?

CYP2D6 genotypes and depressive symptoms during late pregnancy and postpartum

Josefsson, Ann; Sydsjö, Gunilla; Berg, Göran; Dahl, Marja-Liisa et al.

Part of Nordic Journal of Psychiatry, p. 61-4, 2004

• DOI for CYP2D6 genotypes and depressive symptoms during late pregnancy and postpartum

Warfarin sensitivity related to CYP2C9, CYP3A5, ABCB1 (MDR1) and other factors

Wadelius, Mia; Sörlin, Kristina; Wallerman, Ola; Karlsson, Jacob et al.

Part of The Pharmacogenomics Journal, p. 40-8, 2004

• DOI for Warfarin sensitivity related to CYP2C9, CYP3A5, ABCB1 (MDR1) and other factors

Gene expression of cytochrome P450 1B1 and 2D6 in leukocytes in human pregnancy

Lind, Anna-Britta; Wadelius, Mia; Darj, Elisabeth; Finnström, Niklas et al.

Part of Pharmacology and Toxicology, p. 295-9, 2003

• DOI for Gene expression of cytochrome P450 1B1 and 2D6 in leukocytes in human pregnancy

Cytochrome P450 genotyping by multiplexed real-time DNA sequencing with Pyrosequencing TM technology

Eriksson, Solveig; Berg, Lars M.; Wadelius, Mia; Alderborn, Anders

Part of Assay and drug development technologies, p. 49-59, 2002

5alfa-reductase 2 polymorphisms as risk factors in prostate cancer

Söderström, Torbjörn; Wadelius, Mia; Andersson, Swen-Olov; Johansson, Jan-Erik et al.

Part of Pharmacogenetics, p. 307-12, 2002

Polymorphisms of NAT2 in relation to sulphasalazine-induced agranulocytosis

Wadelius, Mia; Stjernberg, Elisabeth; Wiholm, Bengt-Erik; Rane, Anders

Part of Pharmacogenetics, p. 35-41, 2000

Polymorphisms in NAT2, CYP2D6, CYP2C19 and GSTP1 and their association with prostate cancer

Wadelius, Mia; Autrup, J.L.; Stubbins, M.J.; Andersson, S.O. et al.

Part of Pharmacogenetics, p. 333-40, 1999

Prostate cancer associated with CYP17 genotype

Wadelius, Mia; Andersson, S.O.; Johansson, J.E.; Wadelius, Claes et al.

Part of Pharmacogenetics, p. 635-9, 1999

A simplified assay for the arylamine N-acetyltransferase 2 polymorphism validated by phenotyping with isoniazid

Smith, C.A.; Wadelius, Mia; Gough, A.C.; Harrison, D.J. et al.

Part of Journal of Medical Genetics, p. 758-60, 1997

• DOI for A simplified assay for the arylamine N-acetyltransferase 2 polymorphism validated by phenotyping with isoniazid

Induction of CYP2D6 in pregnancy

Wadelius, Mia; Darj, Elisabeth; Frenne, Gunilla; Rane, Anders

Part of Clinical Pharmacology and Therapeutics, p. 400-7, 1997

• DOI for Induction of CYP2D6 in pregnancy

Lamotrigine and toxic epidermal necrolysis

Wadelius, Mia; Karlsson, Torbjörn; Wadelius, Claes; Rane, Anders

Part of The Lancet, p. 1041, 1996

• DOI for Lamotrigine and toxic epidermal necrolysis

Predicting the relative importance of genetic, clinical and demographic factors on warfarin dose in children using pharmacometric modelling

Hamberg, Anna-Karin; Wadelius, Mia; Friberg, Lena E; Biss, Tina T et al.

Pharmacogenomics in pediatric oncology patients with solid tumors related to chemotherapy-induced toxicity: A systematic review

Hansson, Paula; Blacker, C; Uvdal, Hanna; Wadelius, Mia et al.

Part of Critical reviews in oncology/hematology, 2025

• DOI for Pharmacogenomics in pediatric oncology patients with solid tumors related to chemotherapy-induced toxicity: A systematic review
• Download full text (pdf) of Pharmacogenomics in pediatric oncology patients with solid tumors related to chemotherapy-induced toxicity: A systematic review

Farmakogenomik: individuell anpassning av läkemedel och dos: [Pharmacogenomics: a cornerstone of Precision Medicine. Genomic Medicine Sweden analyses genotypes associated with serious drug toxicity or therapeutic failure]

Eliasson, Erik; Wadelius, Mia

Part of Läkartidningen, 2021

Technological readiness and implementation of genomic-driven precision medicine for complex diseases

Franks, P. W.; Melén, E.; Friedman, M.; Sundström, Johan et al.

Part of Journal of Internal Medicine, p. 602-620, 2021

• DOI for Technological readiness and implementation of genomic-driven precision medicine for complex diseases
• Download full text (pdf) of Technological readiness and implementation of genomic-driven precision medicine for complex diseases

CYP2C9, VKORC1, and CYP4F2 polymorphisms and pediatric warfarin maintenance dose: a systematic review and meta-analysis

Takeuchi, Masanobu; Kobayashi, Tohru; Biss, Tina; Kamali, Farhad et al.

Part of The Pharmacogenomics Journal, p. 306-319, 2020

• DOI for CYP2C9, VKORC1, and CYP4F2 polymorphisms and pediatric warfarin maintenance dose: a systematic review and meta-analysis

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics-Guided Warfarin Dosing: 2017 Update

Johnson, JA; Caudle, KE; Gong, L; Whirl-Carrillo, M et al.

Part of Clinical Pharmacology and Therapeutics, p. 397-404, 2017

• DOI for Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics-Guided Warfarin Dosing: 2017 Update
• Download full text (pdf) of Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics-Guided Warfarin Dosing: 2017 Update

Influence of APOE Gene Polymorphism on Interindividual and Interethnic Warfarin Dosage Requirement: A Systematic Review and Meta-Analysis

Yu, Wan-ying; Sun, Xue; Wadelius, Mia; Huang, Lihua et al.

Part of Cardiovascular Therapeutics, p. 297-307, 2016

• DOI for Influence of APOE Gene Polymorphism on Interindividual and Interethnic Warfarin Dosage Requirement: A Systematic Review and Meta-Analysis

Oral anticoagulation: a critique of recent advances and controversies

Pirmohamed, Munir; Kamali, Farhad; Daly, Ann K.; Wadelius, Mia

Part of TIPS - Trends in Pharmacological Sciences, p. 153-163, 2015

• DOI for Oral anticoagulation: a critique of recent advances and controversies

Phenotype Standardization of Angioedema in the Head and Neck Region Caused by Agents Acting on the Angiotensin System

Wadelius, Mia; Marshall, S. E.; Islander, G.; Nordang, Leif et al.

Part of Clinical Pharmacology and Therapeutics, p. 477-481, 2014

• DOI for Phenotype Standardization of Angioedema in the Head and Neck Region Caused by Agents Acting on the Angiotensin System
• Download full text (pdf) of Phenotype Standardization of Angioedema in the Head and Neck Region Caused by Agents Acting on the Angiotensin System

Characteristics associated with drug-induced liver injury from interferon beta in multiple sclerosis patients

Kowalec, Kaarina; Kingwell, Elaine; Yoshida, Eric M.; Marrie, Ruth Ann et al.

Part of Expert Opinion on Drug Safety, p. 1305-1317, 2014

• DOI for Characteristics associated with drug-induced liver injury from interferon beta in multiple sclerosis patients

Phenotype Standardization for Statin-Induced Myotoxicity

Alfirevic, A.; Neely, D.; Armitage, J.; Chinoy, H. et al.

Part of Clinical Pharmacology and Therapeutics, p. 470-476, 2014

• DOI for Phenotype Standardization for Statin-Induced Myotoxicity
• Download full text (pdf) of Phenotype Standardization for Statin-Induced Myotoxicity

Pharmacogenetics-based warfarin dosing in children

Hamberg, Anna-Karin; Wadelius, Mia

Part of Pharmacogenomics (London), p. 361-374, 2014

• DOI for Pharmacogenetics-based warfarin dosing in children

Prediction of warfarin dose: why, when and how?

Eriksson, Niclas; Wadelius, Mia

Part of Pharmacogenomics (London), p. 429-440, 2012

• DOI for Prediction of warfarin dose: why, when and how?

Cost-effectiveness of pharmacogenetics in anticoagulation: international differences in healthcare systems and costs

Verhoef, Talitha I.; Redekop, William K.; van Schie, Rianne M. F.; Bayat, Samira et al.

Part of Pharmacogenomics (London), p. 1405-1417, 2012

• DOI for Cost-effectiveness of pharmacogenetics in anticoagulation: international differences in healthcare systems and costs

Practical recommendations for pharmacogenomics-based prescription: 2010 ESF-UB Conference on Pharmacogenetics and Pharmacogenomics

Becquemont, Laurent; Alfirevic, Ana; Amstutz, Ursula; Brauch, Hiltrud et al.

Part of Pharmacogenomics (London), p. 113-124, 2011

• DOI for Practical recommendations for pharmacogenomics-based prescription: 2010 ESF-UB Conference on Pharmacogenetics and Pharmacogenomics

Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 Genotypes and Warfarin Dosing

Johnson, J. A.; Gong, L.; Whirl-Carrillo, M.; Gage, B. F. et al.

Part of Clinical Pharmacology and Therapeutics, p. 625-629, 2011

• DOI for Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 Genotypes and Warfarin Dosing

Pharmacogenetics of warfarin: current status and future challenges

Wadelius, Mia; Pirmohamed, Munir

Part of The Pharmacogenomics Journal, p. 99-111, 2007

• DOI for Pharmacogenetics of warfarin: current status and future challenges

Chapter 73: Pharmacogenetics

McMillin, Gwendolyn A; Wadelius, Mia; Pratt, Victoria M

Part of Tietz Textbook of Laboratory Medicine, 7th Edition, Elsevier, 2022

Chapter 46: Pharmacogenetics

McMillin, Gwendolyn A; Wadelius, Mia; Pratt, Victoria M

Part of Tietz Fundamentals of Clinical Chemistry, 8th edition, Elsevier, 2018

Chapter 54: Pharmacogenetics

McMillin, Gwendolyn A; Wadelius, Mia; Pratt, Victoria M

Part of Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 6th edition, Elsevier, 2017

Risk of venous thromboembolism after SARS-CoV-2 vaccination - evidence from genome-wide association study and population-based observational study

Attelind, Sofia; Eriksson, Niclas; Cavalli, Marco; Xu, Yiyi et al.

2026

Network-Based Analysis of Protein Interactions among Drugs and Adverse Reactions: Identifying Phenotype-Groupings and Key Genes

Ås, Joel; Eriksson, Niclas; Hallberg, Pär; Wadelius, Mia