Lars Gedda

Lyophilization of Curcumin-Loaded Lipodisks: pre-and post-processing evaluation of formulation characteristics

Ali, Sajid; Silva, Luís; Gedda, Lars; Eskner, Ebba et al.

Part of International Journal of Pharmaceutics, 2026

DOI for Lyophilization of Curcumin-Loaded Lipodisks: pre-and post-processing evaluation of formulation characteristics
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Revealing the Morphology of Small Multilamellar Lipid Nanoparticles (SMLPs) made by In-Vial Homogenization

Akcesme, Sevda; Schmager, Stefanie; Al-Tikriti, Yassir; Gedda, Lars et al.

Part of European Journal of Pharmaceutical Sciences, 2026

Spontaneous formation of small and ultrasmall unilamellar vesicles in mixtures of drug surfactant and phospholipid: Effect of chemical structure of phospholipid tails on vesicle size

Forooqi Motlaq, Vahid; Gedda, Lars; Edwards, Katarina; Doutch, James et al.

Part of Journal of Colloid and Interface Science, p. 1008-1018, 2025

Development and in vitro evaluation of lipodisks optimized for co-delivery of chemotherapeutic drugs and membranolytic anticancer peptides

Silva, Luis; Ali, Sajid; Gedda, Lars; Agmo Hernández, Víctor et al.

Part of Journal of Colloid and Interface Science, 2025

Novel thermosensitive small multilamellar lipid nanoparticles with promising release characteristics made by dual centrifugation

Koehler, Jonas K.; Schmager, Stefanie; Schnur, Johannes; Gedda, Lars et al.

Part of European Journal of Pharmaceutical Sciences, 2025

Investigation of supramolecular structures in various aqueous solutions of an amyloid forming peptide using small-angle X-ray scattering

Brunzell, Ellen; Sigfridsson, Kalle; Gedda, Lars; Edwards, Katarina et al.

Part of Soft Matter, p. 2272-2279, 2024

Dual centrifugation as a novel and efficient method for the preparation of lipodisks

Ali, Sajid; Koehler, Jonas K.; Silva, Luís; Gedda, Lars et al.

Part of International Journal of Pharmaceutics, 2024

A closer look at calcium-induced interactions between phosphatidylserine-(PS) doped liposomes and the structural effects caused by inclusion of gangliosides or polyethylene glycol- (PEG) modified lipids

Grad, Philipp; Edwards, Katarina; Gedda, Lars; Agmo Hernández, Víctor

Part of Biochimica et Biophysica Acta - Biomembranes, 2024

Spontaneous Formation of Ultrasmall Unilamellar Vesicles in Mixtures of an Amphiphilic Drug and a Phospholipid

Forooqi Motlaq, Vahid; Gedda, Lars; Edwards, Katarina; Doutch, James et al.

Part of Langmuir, p. 11337-11344, 2023

Excited-state and charge-carrier dynamics in binary conjugated polymer dots towards efficient photocatalytic hydrogen evolution

Liu, Aijie; Wang, Sicong; Song, Hongwei; Liu, Yawen et al.

Part of Physical Chemistry, Chemical Physics - PCCP, p. 2935-2945, 2023

Tailoring the Lamellarity of Liposomes Prepared by Dual Centrifugation

Koehler, Jonas K. K.; Gedda, Lars; Wurster, Leonie; Schnur, Johannes et al.

Part of Pharmaceutics, 2023

Vesicle-enriched secretomes alter bacterial competitive abilities and are drivers of evolution in microbial communities

Warsi, Omar M.; Gedda, Lars; Edwards, Katarina; Andersson, Dan I.

Part of FEMS Microbiology Ecology, 2023

Structural Characterization Study of a Lipid Nanocapsule Formulation Intended for Drug Delivery Applications Using Small-Angle Scattering Techniques

Urimi, Dileep; Hellsing, Maja; Mahmoudi, Najet; Soderberg, Christopher et al.

Part of Molecular Pharmaceutics, p. 1068-1077, 2022

Polymer Dots as Photoactive Membrane Vesicles for [FeFe]-Hydrogenase Self-Assembly and Solar-Driven Hydrogen Evolution

Pavliuk, Mariia V.; Lorenzi, Marco; Morado, Dustin R.; Gedda, Lars et al.

Part of Journal of the American Chemical Society, p. 13600-13611, 2022

Influence of Chain Length of Gradient and Block Copoly(2-oxazoline)s on Self-Assembly and Drug Encapsulation

Sedlacek, Ondrej; Bardoula, Valentin; Vuorimaa-Laukkanen, Elina; Gedda, Lars et al.

Part of Small, 2022

DOI for Influence of Chain Length of Gradient and Block Copoly(2-oxazoline)s on Self-Assembly and Drug Encapsulation

Investigation of the enhanced ability of bile salt surfactants to solubilize phospholipid bilayers and form mixed micelles.

Forooqi Motlaq, Vahid; Ortega-Holmberg, Mattias; Edwards, Katarina; Gedda, Lars et al.

Part of Soft Matter, p. 7769-7780, 2021

DOI for Investigation of the enhanced ability of bile salt surfactants to solubilize phospholipid bilayers and form mixed micelles.

Formulation development and upscaling of lipid nanocapsules as a drug delivery system for a novel cyclic GMP analogue intended for retinal drug delivery

Urimi, Dileep; Widenbring, Ronja; Garcia, Raul Oswaldo Perez; Gedda, Lars et al.

Part of International Journal of Pharmaceutics, p. 120640, 2021

Panchromatic Ternary Polymer Dots Involving Sub-Picosecond Energy and Charge Transfer for Efficient and Stable Photocatalytic Hydrogen Evolution

Liu, Aijie; Gedda, Lars; Axelsson, Martin; Pavliuk, Mariia et al.

Part of Journal of the American Chemical Society, p. 2875-2885, 2021

Effect of gangliosides on structure and integrity of polyethylene glycol(PEG)-stabilized liposomes

Grad, Philipp; Gedda, Lars; Edwards, Katarina

Part of Journal of Colloid and Interface Science, p. 281-289, 2020

Tumor-Targeted Delivery of the p53-Activating Peptide VIP116 with PEG-Stabilized Lipodisks

Lundsten, Sara; Hernandez, Victor Agmo; Gedda, Lars; Sarén, Tina et al.

Part of Nanomaterials, 2020

Osmoprotective effect of ubiquinone in lipid vesicles modelling the E. coli plasma membrane

Eriksson, Emma K.; Edwards, Katarina; Grad, Philipp; Gedda, Lars et al.

Part of Biochimica et Biophysica Acta - Biomembranes, p. 1388-1396, 2019

EGF-targeting lipodisks for specific delivery of poorly water-soluble anticancer agents to tumour cells

Ahlgren, Sara; Fondell, Amelie; Gedda, Lars; Edwards, Katarina

Part of RSC Advances, p. 22178-22186, 2017

17AAG-induced internalisation of HER2- specific Affibody molecules

Göstring, Lovisa; Lindegren, Sture; Gedda, Lars

Part of Oncology Reports, p. 2574-2580, 2016

DOI for 17AAG-induced internalisation of HER2- specific Affibody molecules

Pre-incubation of chemically crosslinked hyaluronan-based hydrogels, loaded with BMP-2 and hydroxyapatite, and its effect on ectopic bone formation

Stenfelt, Sonya; Hulsart-Billström, Gry; Gedda, Lars; Bergman, Kristoffer et al.

Part of Journal of materials science. Materials in medicine, p. 1013-1023, 2014

DOI for Pre-incubation of chemically crosslinked hyaluronan-based hydrogels, loaded with BMP-2 and hydroxyapatite, and its effect on ectopic bone formation

Characterization of recombinant human bone morphogenetic protein-2 delivery from injectable hyaluronan-based hydrogels by means of I-125-radiolabelling

Piskounova, Sonya; Gedda, Lars; Hulsart-Billström, Gry; Hilborn, Jöns et al.

Part of Journal of Tissue Engineering and Regenerative Medicine, p. 821-830, 2014

DOI for Characterization of recombinant human bone morphogenetic protein-2 delivery from injectable hyaluronan-based hydrogels by means of I-125-radiolabelling

Evaluation of Real-Time Immunohistochemistry and Interaction Map as an Alternative Objective Assessment of HER2 Expression in Human Breast Cancer Tissue

Gedda, Lars; Björkelund, Hanna; Lebel, Lena; Asplund, Anna et al.

Part of Applied immunohistochemistry & molecular morphology (Print), p. 497-505, 2013

DOI for Evaluation of Real-Time Immunohistochemistry and Interaction Map as an Alternative Objective Assessment of HER2 Expression in Human Breast Cancer Tissue

Morphological differences in BMP-2-induced ectopic bone between solid and crushed hyaluronan hydrogel templates

Hulsart-Billström, Gry; Piskounova, Sonya; Gedda, Lars; Andersson, Britt-Marie et al.

Part of Journal of materials science. Materials in medicine, p. 1201-1209, 2013

DOI for Morphological differences in BMP-2-induced ectopic bone between solid and crushed hyaluronan hydrogel templates

Resolving the EGF-EGFR interaction characteristics through a multiple-temperature, multiple-inhibitor, real-time interaction analysis approach

Björkelund, Hanna; Gedda, Lars; Malmqvist, Magnus; Andersson, Karl

Part of Molecular and Clinical Oncology, p. 343-352, 2013

DOI for Resolving the EGF-EGFR interaction characteristics through a multiple-temperature, multiple-inhibitor, real-time interaction analysis approach

Generation and Evaluation of Bispecific Affibody Molecules for Simultaneous Targeting of EGFR and HER2

Ekerljung, Lina; Wållberg, Helena; Sohrabian, Azita; Andersson, Karl et al.

Part of Bioconjugate chemistry, p. 1802-1811, 2012

DOI for Generation and Evaluation of Bispecific Affibody Molecules for Simultaneous Targeting of EGFR and HER2

The HER2-binding Affibody Molecule (Z_HER2:342)₂ Increases Radiosensitivity in SKBR-3 cells

Ekerljung, Lina; Lennartsson, Johan; Gedda, Lars

Part of PLOS ONE, 2012

Cellular effects of HER3-specific affibody molecules

Göstring, Lovisa; Malm, Magdalena; Höidén-Guthenberg, Ingmarie; Frejd, Fredrik et al.

Part of PLOS ONE, 2012

Improved bone formation by altering surface area of hyaluronan-based hydrogel carrier for bone morphogenetic protein-2

Billström, Gry Hulsart; Piskounova, Sonya; Gedda, Lars; Hilborn, Jöns et al.

Part of Bone, 2012

DOI for Improved bone formation by altering surface area of hyaluronan-based hydrogel carrier for bone morphogenetic protein-2

The importance of proper protein handling and detection for the design of a BMP-2 release system

Piskounova, Sonya; Gedda, Lars; Hulsart Billström, Gry; Hilborn, Jöns et al.

Part of Journal of Tissue Engineering and Regenerative Medicine, p. 322-322, 2012

DOI for The importance of proper protein handling and detection for the design of a BMP-2 release system

Experimental radionuclide therapy of HER2-expressing xenografts using two-step targeting Nuclisome-particles

Gedda, Lars; Fondell, Amelie; Lundqvist, Hans; Park, John et al.

Part of Journal of Nuclear Medicine, p. 480-487, 2012

DOI for Experimental radionuclide therapy of HER2-expressing xenografts using two-step targeting Nuclisome-particles

Nuclisome: targeting the tumor cell nucleus

Gedda, Lars; Edwards, Katarina

Part of Tumor Biology, p. 661-667, 2012

Combining phage and staphylococcal surface display for generation of ErbB3-specific Affibody molecules

Kronqvist, Nina; Malm, Magdalena; Göstring, Lovisa; Gunneriusson, Elin et al.

Part of Protein Engineering Design & Selection, p. 385-396, 2011

DOI for Combining phage and staphylococcal surface display for generation of ErbB3-specific Affibody molecules

Avoiding false negative results in specificity analysis of protein-protein interactions

Björkelund, Hanna; Gedda, Lars; Andersson, Karl

Part of Journal of Molecular Recognition, p. 81-89, 2011

DOI for Avoiding false negative results in specificity analysis of protein-protein interactions

Gefitinib Induces Epidermal Growth Factor Receptor Dimers Which Alters the Interaction Characteristics with (125)I-EGF

Björkelund, Hanna; Gedda, Lars; Barta, Pavel; Malmqvist, Magnus et al.

Part of PLOS ONE, 2011

DOI for Gefitinib Induces Epidermal Growth Factor Receptor Dimers Which Alters the Interaction Characteristics with (125)I-EGF

Comparing the epidermal growth factor interaction with four different cell lines: intriguing effects imply strong dependency of cellular context

Björkelund, Hanna; Gedda, Lars; Andersson, Karl

Part of PLoS ONE, 2011

DOI for Comparing the epidermal growth factor interaction with four different cell lines: intriguing effects imply strong dependency of cellular context

In vitro evaluation and biodistribution of HER2-targeted liposomes loaded with an 125I-labelled DNA-intercalator

Fondell, Amelie; Edwards, Katarina; Unga, Johan; Kullberg, Erika et al.

Part of Journal of drug targeting (Print), p. 846-855, 2011

DOI for In vitro evaluation and biodistribution of HER2-targeted liposomes loaded with an 125I-labelled DNA-intercalator

Oncolytic adenovirus modified with somatostatin motifs for selective infection of neuroendocrine tumor cells

Leja, Justyna; Yu, Di; Nilsson, Berith; Gedda, Lars et al.

Part of Gene Therapy, p. 1052-1062, 2011

DOI for Oncolytic adenovirus modified with somatostatin motifs for selective infection of neuroendocrine tumor cells

Nuclisome: a novel concept for radionuclide therapy using targeting liposomes

Fondell, Amelie; Edwards, Katarina; Ickenstein, Ludger M; Sjöberg, Stefan et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, p. 114-123, 2010

DOI for Nuclisome: a novel concept for radionuclide therapy using targeting liposomes

Blocking EGFR in the liver improves the tumor-to-liver uptake ratio of radiolabeled EGF

Kareem, Heewa; Sandström, Karl; Elia, Ronny; Gedda, Lars et al.

Part of Tumor Biology, p. 79-87, 2010

DOI for Blocking EGFR in the liver improves the tumor-to-liver uptake ratio of radiolabeled EGF

Real-time immunohistochemistry analysis of embedded tissue

Gedda, Lars; Björkelund, Hanna; Andersson, Karl

Part of Applied Radiation and Isotopes, p. 2372-2376, 2010

DOI for Real-time immunohistochemistry analysis of embedded tissue

Engineering and characterization of a bispecific HER2 x EGFR-binding affibody molecule

Friedman, Mikaela; Lindstrom, Sara; Ekerljung, Lina; Andersson-Svahn, Helene et al.

Part of Biotechnology and applied biochemistry, p. 121-131, 2009

DOI for Engineering and characterization of a bispecific HER2 x EGFR-binding affibody molecule

Hsp90 is expressed and represents a therapeutic target in human oesophageal cancer using the inhibitor 17-allylamino-17-demethoxygeldanamycin

Wu, Xuping; Wanders, Alkwin; Wardega, Piotr; Tinge, B. et al.

Part of British Journal of Cancer, p. 334-343, 2009

DOI for Hsp90 is expressed and represents a therapeutic target in human oesophageal cancer using the inhibitor 17-allylamino-17-demethoxygeldanamycin

Flow cytometric in situ proximity ligation analyses of protein interactions and post-translational modification of the epidermal growth factor receptor family

Leuchowius, Karl-Johan; Weibrecht, Irene; Landegren, Ulf; Gedda, Lars et al.

Part of Cytometry: Part A, p. 833-839, 2009

DOI for Flow cytometric in situ proximity ligation analyses of protein interactions and post-translational modification of the epidermal growth factor receptor family

Dimeric HER2-specific affibody molecules inhibit proliferation of the SKBR-3 breast cancer cell line

Ekerljung, Lina; Lindborg, Malin; Gedda, Lars; Frejd, Fredrik Y. et al.

Part of Biochemical and Biophysical Research Communications - BBRC, p. 489-494, 2008

DOI for Dimeric HER2-specific affibody molecules inhibit proliferation of the SKBR-3 breast cancer cell line

Targeting EGFR and HER2 with 211At-labeled molecules: unexpected and expected dose-effect relations in cultured tumor cells

Carlsson, Jörgen; Steffen, Ann-Charlott; Sundberg, Åsa L.; Vikström, Mikael et al.

Part of Current radiopharmaceuticals, p. 225-233, 2008

[Lu-177]pertuzumab: Experimental therapy of HER-2-expressing xenografts

Persson, Mikael; Gedda, Lars; Lundqvist, Hans; Tolmachev, Vladimir et al.

Part of Cancer Research, p. 326-331, 2007

DOI for [Lu-177]pertuzumab: Experimental therapy of HER-2-expressing xenografts

In vitro evaluation of two polyhedral boron anion derivatives as linkers for attachment of radioiodine to the anti-HER2 monoclonal antibody trastuzumab

Persson, Mikael; Sivaev, Igor; Winberg, Karl-Johan; Gedda, Lars et al.

Part of Cancer Biotherapy and Radiopharmaceuticals, p. 585-596, 2007

DOI for In vitro evaluation of two polyhedral boron anion derivatives as linkers for attachment of radioiodine to the anti-HER2 monoclonal antibody trastuzumab

Penetration of tumor therapy interesting substances in non-vascularized metastases.: Review of studies in multicellular spheroids

Carlsson, Jörgen; Gedda, Lars

Part of Current Cancer Therapy Reviews, p. 293-304, 2006

DOI for Penetration of tumor therapy interesting substances in non-vascularized metastases.: Review of studies in multicellular spheroids

Planning for intracavitary anti-EGFR radionuclide therapy of gliomas: Literature review and data on EGFR expression

Carlsson, Jörgen; Ren, Z. P.; Wester, K.; Sundberg, A. L. et al.

Part of Journal of Neuro-Oncology, p. 33-45, 2006

DOI for Planning for intracavitary anti-EGFR radionuclide therapy of gliomas: Literature review and data on EGFR expression

A novel I-125-labeled daunorubicin derivative for radionuclide-based cancer therapy

Ickenstein, Ludger M.; Edwards, Katarina; Sjöberg, Stefan; Carlsson, Jörgen et al.

Part of Nuclear Medicine and Biology, p. 773-783, 2006

DOI for A novel I-125-labeled daunorubicin derivative for radionuclide-based cancer therapy

Astatinated trastuzumab, a putative agent for radionuclide immunotherapy of ErbB2-expressing tumours

Persson, Mikael I.; Gedda, Lars; Jensen, H. J.; Lundqvist, Hans et al.

Part of Oncology Reports, p. 673-80, 2006

111In-benzyl-DTPA-ZHER2:342, an affibody-based conjugate for in vivo imaging of HER2 expression in malignant tumors

Tolmachev, Vladimir; Nilsson, Fredrik Y.; Widström, Charles; Andersson, Karl et al.

Part of Journal of Nuclear Medicine, p. 846-53, 2006

Penetration of tumor therapy interesting substances in non-vascularized metastases; Review of studies in cellular spheroids

Carlsson, Jörgen; Gedda, Lars

Part of Current Cancer Therapy Reviews, p. 293-304, 2006

An aminoacridine derivative for radionuclide therapy: DNA binding properties studied in a novel cell-free in vitro assay

Kullberg, Erika Bohl; Stenerlöw, Bo; Ghirmai, Senait; Lundqvist, Hans et al.

Part of International Journal of Oncology, p. 1355-60, 2005

[(177)Lu]pertuzumab: experimental studies on targeting of HER-2 positive tumour cells

Persson, Mikael; Tolmachev, Vladimir; Andersson, Karl; Gedda, Lars et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, p. 1457-62, 2005

DOI for [(177)Lu]pertuzumab: experimental studies on targeting of HER-2 positive tumour cells

An Aminoacridine Derivative for Radionuclide Therapy: Dna-Binding Properties Studied in a Novel Cell-Free in vitro Assay

Kullberg, E-B.; Stenerlöw, B.; Ghirmait, Senait; Lundqvist, Hans et al.

Part of Int. J. Onc., p. 1355-1360, 2005

EGF-receptor targeted liposomes with boronated acridine: growth inhibition of cultured glioma cells after neutron irradiation

Kullberg, Erika Bohl; Wei, Qichun; Capala, Jacek; Giusti, Valerio et al.

Part of International Journal of Radiation Biology, p. 621-629, 2005

DOI for EGF-receptor targeted liposomes with boronated acridine: growth inhibition of cultured glioma cells after neutron irradiation

Identification and characterization of a novel splicing variant of vesicular monoamine transporter 1

Essand, Magnus; Vikman, Sofia; Grawé, Jan; Gedda, Lars et al.

Part of Journal of Molecular Endocrinology, p. 489-501, 2005

DOI for Identification and characterization of a novel splicing variant of vesicular monoamine transporter 1

Radionuklidterapi - möjlig väg mot bättre behandling av cancer: Hindret är bristen på kommersiellt tillgängliga nuklider i kliniken

Lundqvist, Hans; Carlsson, Jörgen; Gedda, Lars; Tolmachev, Vladimir et al.

Part of Läkartidningen, p. 1000-1006, 2004

[177Lu]Bz-DTPA-EGF: Preclinical characterization of a potential radionuclide targeting agent against glioma

Sundberg, Åsa Liljegren; Gedda, Lars; Orlova, Anna; Bruskin, Alexander et al.

Part of Cancer Biotherapy and Radiopharmaceuticals, p. 195-204, 2004

DOI for [177Lu]Bz-DTPA-EGF: Preclinical characterization of a potential radionuclide targeting agent against glioma

Comparative biodistribution of potential anti-glioblastoma conjugates [111In]DTPA-hEGF and [111In]Bz-DTPA-hEGF in normal mice

Tolmachev, Vladimir; Orlova, Anna; Wei, Qichun; Bruskin, Alexander et al.

Part of Cancer Biotherapy and Radiopharmaceuticals, p. 491-501, 2004

DOI for Comparative biodistribution of potential anti-glioblastoma conjugates [111In]DTPA-hEGF and [111In]Bz-DTPA-hEGF in normal mice

Introductory experiments on ligand liposomes as delivery agents for boronneutron capture therapy

Bohl Kullberg, E; Carlsson, Jörgen; Edwards, Katarina; Capala, J et al.

Part of International Journal of Oncology, p. 461-467, 2003

Trastuzumab-conjugated boron-containing liposomes for tumor-celltargeting; development and cellular studies.

Wei, Q; Kullberg, EB; Gedda, L

Part of Int J Oncol, p. 1159, 2003

[111In]Bz-DTPA-hEGF: Preparation and in vitro characterization of a potential anti-glioblastoma targeting agent

Sundberg, Åsa Liljegren; Orlova, Anna; Bruskin, Alexander; Gedda, Lars et al.

Part of Cancer Biotherapy and Radiopharmaceuticals, p. 643-54, 2003

DOI for [111In]Bz-DTPA-hEGF: Preparation and in vitro characterization of a potential anti-glioblastoma targeting agent

Ligand liposomes and boron neutron capture therapy

Carlsson, Jörgen; Bohl Kullberg, Erika; Capala, Jacek; Sjöberg, Stefan et al.

Part of Journal of Neuro-Oncology, p. 47, 2003

Combined effect of gefitinib ('Iressa', ZD1839) and targeted radiotherapy with 211At-EGF

Sundberg, Åsa Liljegren; Almqvist, Ylva; Orlova, Anna; Blomquist, Erik et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, p. 1348-56, 2003

DOI for Combined effect of gefitinib ('Iressa', ZD1839) and targeted radiotherapy with 211At-EGF

Cellular retention of radioactivity and increased radiation dose: Modelexperiments with EGF-dextran

Sundberg, Åsa Liljegren; Blomquist, Erik; Carlsson, Jörgen; Steffen, Ann-Chalott et al.

Part of Nuclear Medicine and Biology, p. 303-315, 2003

DOI for Cellular retention of radioactivity and increased radiation dose: Modelexperiments with EGF-dextran

Tumor-cell targeted EGF liposomes loaded with boronated acridine: Uptake and processing

Kullberg, Erika Bohl; Nestor, Marika; Gedda, Lars

Part of Pharmaceutical research, p. 229-236, 2003

DOI for Tumor-cell targeted EGF liposomes loaded with boronated acridine: Uptake and processing

Development of EGF-conjugated liposomes for targeted delivery of boronated DNA-binding agents

Bohl Kullberg, Erika; Bergstrand, Nill; Carlsson, Jörgen; Edwards, Katarina et al.

Part of Bioconjugate chemistry, p. 737-743, 2002

DOI for Development of EGF-conjugated liposomes for targeted delivery of boronated DNA-binding agents

Comparative biodistribution of the radiohalogenated (Br, I and At) antibody A33: Implications for in vivo dosimetry

Orlova, Anna; Höglund, Johanna; Lubberink, Mark; Lebeda, Ondrej et al.

Part of Cancer Biotherapy and Radiopharmaceuticals, p. 385-96, 2002

DOI for Comparative biodistribution of the radiohalogenated (Br, I and At) antibody A33: Implications for in vivo dosimetry

Internalisation and retention of EGF-dextran associated radioactivity intransfected Chinese hamster ovary cells expressing the human EGF-receptor.

Olsson, P; Collins, VP; Liu, L; Gedda, L et al.

Part of Int J Oncol, p. 1057, 2002

A new antibody recognizing the vIII mutation of human epidermal growthfactor receptor.

Ohman, L; Gedda, L; Hesselager, G; Larsson, R et al.

Part of Tumour Biol, p. 61, 2002

Effects of dextranation on the uptake of peptides in micrometastases:studies on binding of EGF in tumor spheroids.

Nilsson, P; Gedda, L; Sjostrom, A; Carlsson, J

Part of Tumour Biol, p. 229, 2001

Cellular processing of (125)I- and (111)in-labeled epidermal growth factor(EGF) bound to cultured A431 tumor cells

Orlova, Anna; Bruskin, Alexander; Sjöström, Anna; Lundqvist, Hans et al.

Part of Nuclear Medicine and Biology, p. 827-35, 2000

DOI for Cellular processing of (125)I- and (111)in-labeled epidermal growth factor(EGF) bound to cultured A431 tumor cells

The influence of lipophilicity on binding of boronated DNA-intercalating compounds in human glioma speroids

Gedda, L; Ghaneolhosseini, H; Nilsson, P; Nyholm, K et al.

Part of Anti-Cancer Drug Design, p. 277-286, 2000

The influence of lipophilicity on binding of boronated DNA-intercalatingcompounds in human glioma spheroids.

Gedda, L; Ghaneolhosseini, H; Nilsson, P; Nyholm, K et al.

Part of Anti-Cancer Drug Des., p. 277, 2000

Closo-dodecaborate(2-) as a linker for iodination of macromolecules: Aspects on conjugation chemistry and biodistribution

Tolmachev, Vladimir; Koziorowski, Jacek; Sivaev, Igor; Lundqvist, Hans et al.

Part of Bioconjugate chemistry, p. 338-45, 1999

DOI for Closo-dodecaborate(2-) as a linker for iodination of macromolecules: Aspects on conjugation chemistry and biodistribution

Conjugate chemistry and cellular processing of EGF-dextran

Carlsson, Jörgen; Blomquist, Erik; Gedda, Lars; Liljegren, Åsa et al.

Part of Acta Oncologica, p. 313-321, 1999

Conjugate chemistry, iodination and cellular binding of mEGF-dextran-tyrosine: preclinical tests in preparation for clinicaltrials

Zhao, Q; Blomquist, E; Bolander, H; Gedda, Lars et al.

Part of International Journal of Molecular Medicine, p. 693-702, 1998

Cytotoxicity and subcellular localization of boronated phenanthridinium analogues.

Gedda, L; Silvander, M; Sjoberg, S; Tjarks, W et al.

Part of Anti-Cancer Drug Des., p. 671, 1998

Uptake of a boronated epidermal growth factor-dextran conjugate in CHOtor expression.

Olsson, P; Gedda, L; Goike, H; Liu, L et al.

Part of Anti-Cancer Drug Des., p. 279, 1998

Chemistry and biology of some low molecular weight boron compounds forboron neutron capture therapy.

Sjoberg, S; Carlsson, J; Ghaneolhosseini, H; Gedda, L et al.

Part of J Neurooncol, p. 41, 1997

Labelling of boron containing compounds with halogen isotopes

Tolmachev, Vladimir; Lundqvist, Hans; Sivaev, Igor; Orlova, Anna et al.

Part of Journal of labelled compounds & radiopharmaceuticals, p. 122, 1997

Epidermal growth factor-DNA conjugate for two-step targeting: development and introductory in vitro evaluation.

Gedda, L; Carlsson, J

Part of Int J Oncology, p. 789, 1997

Development and in vitro studies of epidermal growth factor-dextranconjugates for boron neutron capture therapy.

Gedda, L; Olsson, P; Ponten, J; Carlsson, J

Part of Bioconjug Chem, p. 584, 1996

Strategy for boron neutron capture therapy against tumor cells with over-expression of the epidermal growth factor-receptor.

Carlsson, J; Gedda, L; Grönvik, C; Hartman, T et al.

Part of International Journal of Radiation Oncology, Biology, Physics, p. 105-15, 1994

Synthesis, radioiodination, DNA binding and cellular uptake of some doxorubicin analogues

Winander, Cecilia; Gedda, Lars; Tolmachev, Vladimir; Sjöberg, Stefan

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