Oleg Dyachok

RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function

Ibrahim, Hazem; Balboa, Diego; Saarimäki-Vire, Jonna; Montaser, Hossam et al.

Part of Diabetologia, p. 1642-1662, 2024

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The β-cell primary cilium is an autonomous Ca²⁺ compartment for paracrine GABA signaling

Sanchez, Gonzalo; Incedal, Tugce Ceren; Prada, Juan; O'Callaghan, Paul et al.

Part of Journal of Cell Biology, 2023

• DOI for The β-cell primary cilium is an autonomous Ca²⁺ compartment for paracrine GABA signaling
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Indicator-dependent differences in detection of local intracellular Ca2+release events evoked by voltage-gated Ca2+entry in pancreatic & beta;-cells

Yang, Mingyu; Dyachok, Oleg; Xu, Yunjian; Gylfe, Erik et al.

Part of Cellular Signalling, 2023

• DOI for Indicator-dependent differences in detection of local intracellular Ca2+release events evoked by voltage-gated Ca2+entry in pancreatic & beta;-cells
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Fluorescent Translocation Reporters for Sub–plasma Membrane cAMP Imaging

Dyachok, Oleg; Xu, Yunjian; Idevall, Olof; Tengholm, Anders

Part of cAMP Signaling, p. 319-338, Humana Press, 2022

• DOI for Fluorescent Translocation Reporters for Sub–plasma Membrane cAMP Imaging

Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells.

Balboa, Diego; Barsby, Tom; Lithovius, Väinö; Saarimäki-Vire, Jonna et al.

Part of Nature Biotechnology, p. 1042-1055, 2022

• DOI for Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells.
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RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function

Ibrahim, Hazem; Balboa, Diego; Saarimäki-Vire, Jonna; Montaser, Hossam et al.

Part of Diabetologia, p. 1642-1662, 2024

• DOI for RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function
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The β-cell primary cilium is an autonomous Ca²⁺ compartment for paracrine GABA signaling

Sanchez, Gonzalo; Incedal, Tugce Ceren; Prada, Juan; O'Callaghan, Paul et al.

Part of Journal of Cell Biology, 2023

• DOI for The β-cell primary cilium is an autonomous Ca²⁺ compartment for paracrine GABA signaling
• Download full text (pdf) of The β-cell primary cilium is an autonomous Ca²⁺ compartment for paracrine GABA signaling

Indicator-dependent differences in detection of local intracellular Ca2+release events evoked by voltage-gated Ca2+entry in pancreatic & beta;-cells

Yang, Mingyu; Dyachok, Oleg; Xu, Yunjian; Gylfe, Erik et al.

Part of Cellular Signalling, 2023

• DOI for Indicator-dependent differences in detection of local intracellular Ca2+release events evoked by voltage-gated Ca2+entry in pancreatic & beta;-cells
• Download full text (pdf) of Indicator-dependent differences in detection of local intracellular Ca2+release events evoked by voltage-gated Ca2+entry in pancreatic & beta;-cells

Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells.

Balboa, Diego; Barsby, Tom; Lithovius, Väinö; Saarimäki-Vire, Jonna et al.

Part of Nature Biotechnology, p. 1042-1055, 2022

• DOI for Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells.
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Opioid precursor protein isoform is targeted to the cell nuclei in the human brain

Kononenko, Olga; Bazov, Igor; Watanabe, Hiroyuki; Gerashchenko, Ganna et al.

Part of Biochimica et Biophysica Acta, p. 246-255, 2017

• DOI for Opioid precursor protein isoform is targeted to the cell nuclei in the human brain

CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion

Abels, Mia; Riva, Matteo; Bennet, Hedvig; Ahlqvist, Emma et al.

Part of Diabetologia, p. 1928-1937, 2016

• DOI for CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion

CART is a novel glucose-dependent peptide with antidiabetic actions in humans

Abels, M.; Riva, M.; Poon, W.; Bennet, H. et al.

Part of Diabetologia, 2015

Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets

Alenkvist, Ida; Dyachok, Oleg; Tian, Geng; Li, Jia et al.

Part of Journal of Endocrinology, p. 267-275, 2014

• DOI for Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets
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Functional differences between aggregated and dispersed insulin-producing cells

Chowdhury, Azazul Islam; Dyachok, Oleg; Tengholm, Anders; Sandler, Stellan et al.

Part of Diabetologia, p. 1557-1568, 2013

• DOI for Functional differences between aggregated and dispersed insulin-producing cells
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Ghrelin Attenuates cAMP-PKA Signaling to Evoke Insulinostatic Cascade in Islet beta-Cells

Dezaki, Katsuya; Damdindorj, Boldbaatar; Sone, Hideyuki; Dyachok, Oleg et al.

Part of Diabetes, p. 2315-2324, 2011

• DOI for Ghrelin Attenuates cAMP-PKA Signaling to Evoke Insulinostatic Cascade in Islet beta-Cells

Ca2+ and cAMP Signaling in Human Embryonic Stem Cell-Derived Dopamine Neurons

Malmersjö, Seth; Liste, Isabel; Dyachok, Oleg; Tengholm, Anders et al.

Part of Stem Cells and Development, p. 1355-1364, 2010

• DOI for Ca2+ and cAMP Signaling in Human Embryonic Stem Cell-Derived Dopamine Neurons

Crosstalk between cAMP- and Zn2+-signalling in insulin secretion

Dyachok, Oleg; Idevall, Olof; Tengholm, Anders; Gylfe, Erik

Part of Diabetologia, 2010

Wnt-5a-induced Phosphorylation of DARPP-32 Inhibits Breast Cancer Cell Migration in a CREB-dependent Manner

Hansen, Christian; Howlin, Jillian; Tengholm, Anders; Dyachok, Oleg et al.

Part of Journal of Biological Chemistry, p. 27533-27543, 2009

• DOI for Wnt-5a-induced Phosphorylation of DARPP-32 Inhibits Breast Cancer Cell Migration in a CREB-dependent Manner

Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion

Dyachok, Oleg; Idevall-Hagren, Olof; Sågetorp, Jenny; Tian, Geng et al.

Part of Cell Metabolism, p. 26-37, 2008

• DOI for Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion
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Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells.

Dyachok, Oleg; Isakov, Yegor; Sågetorp, Jenny; Tengholm, Anders

Part of Nature, p. 349-52, 2006

cAMP oscillations restrict protein kinase A redistribution in insulin-secreting cells.

Dyachok, O; Sagetorp, J; Isakov, Y; Tengholm, A

Part of Biochem Soc Trans, p. 498-501, 2006

Feedback activation of phospholipase C via intracellular mobilization and store-operated influx of Ca²⁺ in insulin-secreting β-cells

Thore, Sophia; Dyachok, Oleg; Gylfe, Erik; Tengholm, Anders

Part of Journal of Cell Science, p. 4463-4471, 2005

• DOI for Feedback activation of phospholipase C via intracellular mobilization and store-operated influx of Ca²⁺ in insulin-secreting β-cells
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Ca²⁺-induced Ca²⁺ release by activation of inositol 1,4,5-trisphosphate receptors in primary pancreatic β-cells

Dyachok, Oleg; Tufveson, Gunnar; Gylfe, Erik

Part of Cell Calcium, p. 1-9, 2004

• DOI for Ca²⁺-induced Ca²⁺ release by activation of inositol 1,4,5-trisphosphate receptors in primary pancreatic β-cells
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Ca²+-induced Ca²+ Release via Inositol 1,4,5-trisphosphate Receptors Is Amplified by Protein Kinase A and Triggers Exocytosis in Pancreatic β-Cells

Dyachok, Oleg; Gylfe, Erik

Part of Journal of Biological Chemistry, p. 45455-45461, 2004

• DOI for Ca²+-induced Ca²+ Release via Inositol 1,4,5-trisphosphate Receptors Is Amplified by Protein Kinase A and Triggers Exocytosis in Pancreatic β-Cells
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Oscillations of Phospholipase C Activity Triggered by Depolarizatio and Ca2+ Influx in Insulin-secreting Cells

Thore, Sophia; Dyachok, Oleg; Tengholm, Anders

Part of The Journal of Biological Chemistry (JBC), p. 19396-19400, 2004

Fluorescent Translocation Reporters for Sub–plasma Membrane cAMP Imaging

Dyachok, Oleg; Xu, Yunjian; Idevall, Olof; Tengholm, Anders

Part of cAMP Signaling, p. 319-338, Humana Press, 2022

• DOI for Fluorescent Translocation Reporters for Sub–plasma Membrane cAMP Imaging