Bengt Sennblad
Head of Division at Department of Cell and Molecular Biology; Molecular Evolution
- E-mail:
- bengt.sennblad@icm.uu.se
- Visiting address:
- Husargatan 3
752 37 UPPSALA - Postal address:
- Box 596
751 24 UPPSALA
Short presentation
I work as a manager of the NBIS Health and Clinical Support team, which is part of the Support unit of the SciLifeLab Bioinformatics platform (NBIS). The team provides advanced bioinformatics support and training to Swedish life science, focusing on studies with medical and health-related questions.
Biography
I have a PhD in Biology and an Associate professorship in Computer Science. My previous research span molecular evolution of plants, probabilistic models and algorithms for studying gene family evolution in a multispecies context, analyses and development of new methods in genome-wide association analysis, particularly in relation to cardiovascular disease.
Research
We mainly work with human data, including genomics, transcriptomics, proteomics, metabolomics and phenotypic/clinical information. Our work includes consultation and hands-on support in study design, data processing, genetic associations, biomarker identification, cancer genomics, multi-omics integration and machine learning. We are engaged in the SciLifeLab & Wallenberg National Program for Data-Driven Life Science (DDLS), by providing bioinformatics support within the DDLS Precision Medicine research area.
For further information about NBIS services and activities, please see https://nbis.se.
Publications
Recent publications
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Part of Microbiology Resource Announcements, 2025
- DOI for Genome sequences of six clinical isolates of Candida parapsilosis exhibiting different degrees and temporal regulation of biofilm formation
- Download full text (pdf) of Genome sequences of six clinical isolates of Candida parapsilosis exhibiting different degrees and temporal regulation of biofilm formation
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Part of PLOS ONE, 2024
- DOI for Towards high-throughput parallel imaging and single-cell transcriptomics of microbial eukaryotic plankton
- Download full text (pdf) of Towards high-throughput parallel imaging and single-cell transcriptomics of microbial eukaryotic plankton
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Part of Rheumatology, p. 3461-3470, 2022
- DOI for Identification and Functional Characterization of a Novel Susceptibility Locus for Small Vessel Vasculitis with MPO-ANCA
- Download full text (pdf) of Identification and Functional Characterization of a Novel Susceptibility Locus for Small Vessel Vasculitis with MPO-ANCA
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The trans-ancestral genomic architecture of glycemic traits
Part of Nature Genetics, p. 840-860, 2021
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Genome-wide association study of circulating interleukin 6 levels identifies novel loci
Part of Human Molecular Genetics, p. 393-409, 2021
- DOI for Genome-wide association study of circulating interleukin 6 levels identifies novel loci
- Download full text (pdf) of Genome-wide association study of circulating interleukin 6 levels identifies novel loci
All publications
Articles in journal
-
Part of Microbiology Resource Announcements, 2025
- DOI for Genome sequences of six clinical isolates of Candida parapsilosis exhibiting different degrees and temporal regulation of biofilm formation
- Download full text (pdf) of Genome sequences of six clinical isolates of Candida parapsilosis exhibiting different degrees and temporal regulation of biofilm formation
-
Part of PLOS ONE, 2024
- DOI for Towards high-throughput parallel imaging and single-cell transcriptomics of microbial eukaryotic plankton
- Download full text (pdf) of Towards high-throughput parallel imaging and single-cell transcriptomics of microbial eukaryotic plankton
-
Part of Rheumatology, p. 3461-3470, 2022
- DOI for Identification and Functional Characterization of a Novel Susceptibility Locus for Small Vessel Vasculitis with MPO-ANCA
- Download full text (pdf) of Identification and Functional Characterization of a Novel Susceptibility Locus for Small Vessel Vasculitis with MPO-ANCA
-
The trans-ancestral genomic architecture of glycemic traits
Part of Nature Genetics, p. 840-860, 2021
-
Genome-wide association study of circulating interleukin 6 levels identifies novel loci
Part of Human Molecular Genetics, p. 393-409, 2021
- DOI for Genome-wide association study of circulating interleukin 6 levels identifies novel loci
- Download full text (pdf) of Genome-wide association study of circulating interleukin 6 levels identifies novel loci
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Part of Scientific Reports, 2021
- DOI for The overlap of genetic susceptibility to schizophrenia and cardiometabolic disease can be used to identify metabolically different groups of individuals
- Download full text (pdf) of The overlap of genetic susceptibility to schizophrenia and cardiometabolic disease can be used to identify metabolically different groups of individuals
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Part of Genes and Immunity, p. 100-108, 2020
- DOI for Analysis of the genetic variants associated with circulating levels of sgp130: Results from the IMPROVE study
- Download full text (pdf) of Analysis of the genetic variants associated with circulating levels of sgp130: Results from the IMPROVE study
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Associations of autozygosity with a broad range of human phenotypes
Part of Nature Communications, 2019
- DOI for Associations of autozygosity with a broad range of human phenotypes
- Download full text (pdf) of Associations of autozygosity with a broad range of human phenotypes
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Part of Genome Biology, 2019
- DOI for Conbase: a software for unsupervised discovery of clonal somatic mutations in single cells through read phasing
- Download full text (pdf) of Conbase: a software for unsupervised discovery of clonal somatic mutations in single cells through read phasing
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Genetic variation in CADM2 as a link between psychological traits and obesity
Part of Scientific Reports, 2019
- DOI for Genetic variation in CADM2 as a link between psychological traits and obesity
- Download full text (pdf) of Genetic variation in CADM2 as a link between psychological traits and obesity
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Breast cancer quantitative proteome and proteogenomic landscape
Part of Nature Communications, 2019
- DOI for Breast cancer quantitative proteome and proteogenomic landscape
- Download full text (pdf) of Breast cancer quantitative proteome and proteogenomic landscape
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H19 Induces Abdominal Aortic Aneurysm Development and Progression
Part of Circulation, p. 1551-1568, 2018
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Part of Nature Communications, 2018
- DOI for GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes
- Download full text (pdf) of GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes
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Part of Atherosclerosis, p. 196-204, 2017
- DOI for Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation
- Download full text (pdf) of Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation