Mats Gustafsson
Professor at Department of Civil and Industrial Engineering; Industrial Engineering and Management
- Telephone:
- +46 18 471 30 42
- Mobile phone:
- +46 73 469 79 83
- E-mail:
- mats.gustafsson@angstrom.uu.se
- Visiting address:
- Ångströmlaboratoriet, Lägerhyddsvägen 1
752 37 Uppsala - Postal address:
- Box 169
751 04 Uppsala
Professor at Department of Medical Sciences; Cancer Pharmacology and Computational Medicine
- Telephone:
- +46 18 611 42 41
- Mobile phone:
- +46 73 469 79 83
- Fax:
- +46 18 611 37 03
- E-mail:
- Mats.Gustafsson@medsci.uu.se
- Visiting address:
- Akademiska sjukhuset, ingång 61
- Postal address:
- Akademiska sjukhuset, ingång 61
751 85 Uppsala

Publications
Recent publications
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Exhaustive in vitro evaluation of the 9-drug cocktail CUSP9 for treatment of glioblastoma
Part of Computers in Biology and Medicine, 2024
- DOI for Exhaustive in vitro evaluation of the 9-drug cocktail CUSP9 for treatment of glioblastoma
- Download full text (pdf) of Exhaustive in vitro evaluation of the 9-drug cocktail CUSP9 for treatment of glioblastoma
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Part of PLOS ONE, 2020
- DOI for COMBSecretomics: a pragmatic methodological framework for higher-order drug combination analysis using secretomics
- Download full text (pdf) of COMBSecretomics: a pragmatic methodological framework for higher-order drug combination analysis using secretomics
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A Novel Multiplex Based Platform for Osteoarthritis Drug Candidate Evaluation
Part of Annals of Biomedical Engineering, p. 2438-2448, 2020
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Part of BMC Bioinformatics, 2019
- DOI for COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining
- Download full text (pdf) of COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining
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Part of PLOS ONE, 2019
- DOI for An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns
- Download full text (pdf) of An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns
All publications
Articles in journal
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Exhaustive in vitro evaluation of the 9-drug cocktail CUSP9 for treatment of glioblastoma
Part of Computers in Biology and Medicine, 2024
- DOI for Exhaustive in vitro evaluation of the 9-drug cocktail CUSP9 for treatment of glioblastoma
- Download full text (pdf) of Exhaustive in vitro evaluation of the 9-drug cocktail CUSP9 for treatment of glioblastoma
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Part of PLOS ONE, 2020
- DOI for COMBSecretomics: a pragmatic methodological framework for higher-order drug combination analysis using secretomics
- Download full text (pdf) of COMBSecretomics: a pragmatic methodological framework for higher-order drug combination analysis using secretomics
-
A Novel Multiplex Based Platform for Osteoarthritis Drug Candidate Evaluation
Part of Annals of Biomedical Engineering, p. 2438-2448, 2020
-
Part of BMC Bioinformatics, 2019
- DOI for COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining
- Download full text (pdf) of COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining
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Part of PLOS ONE, 2019
- DOI for An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns
- Download full text (pdf) of An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns
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Investigations Of Cytokine Interplay With An In Vitro Model Of Osteoarthritis
Part of Osteoarthritis and Cartilage, 2018
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Part of BMC Bioinformatics, 2018
- DOI for COMBImage: a modular parallel processing framework for pairwise drug combination analysis that quantifies temporal changes in label-free video microscopy movies
- Download full text (pdf) of COMBImage: a modular parallel processing framework for pairwise drug combination analysis that quantifies temporal changes in label-free video microscopy movies
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Part of Journal of Statistical Software, p. 1-30, 2018
- DOI for Developer-Friendly and Computationally Efficient Predictive Modeling without Information Leakage: The emil Package for R
- Download full text (pdf) of Developer-Friendly and Computationally Efficient Predictive Modeling without Information Leakage: The emil Package for R
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Part of Pattern Recognition, p. 133-143, 2018
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Part of Leukemia Research, p. 41-46, 2017
- DOI for Towards repositioning of quinacrine for treatment of acute myeloid leukemia - Promising synergies and in vivo effects.
- Download full text (pdf) of Towards repositioning of quinacrine for treatment of acute myeloid leukemia - Promising synergies and in vivo effects.
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Part of Oncotarget, p. 103952-103967, 2017
- DOI for Bliss and Loewe interaction analyses of clinically relevant drug combinations in human colon cancer cell lines reveal complex patterns of synergy and antagonism
- Download full text (pdf) of Bliss and Loewe interaction analyses of clinically relevant drug combinations in human colon cancer cell lines reveal complex patterns of synergy and antagonism
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Part of Metabolomics, 2017
- DOI for Mass spectrometry based metabolomics for in vitro systems pharmacology: pitfalls, challenges, and computational solutions.
- Download full text (pdf) of Mass spectrometry based metabolomics for in vitro systems pharmacology: pitfalls, challenges, and computational solutions.
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Targeting tumor cells based on Phosphodiesterase 3A expression
Part of Experimental Cell Research, p. 308-315, 2017
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Part of Cell Reports, p. 2994-3009, 2016
- DOI for Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition
- Download full text (pdf) of Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition
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Part of Scandinavian Journal of Rheumatology, p. 44-45, 2016
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Part of PLOS ONE, 2016
- DOI for A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients
- Download full text (pdf) of A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients
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Part of CELL CHEMICAL BIOLOGY, p. 1428-1438, 2016
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Part of Biochemical Pharmacology, p. 40-49, 2016
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Repositioning Of Quinacrine For Treatment Of Acute Myeloid Leukemia - Synergies And In Vivo Effects
Part of Haematologica, p. 367-368, 2016
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Part of Chemometrics and Intelligent Laboratory Systems, p. 24-32, 2015
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Part of Molecular Cancer Therapeutics, p. 1504-1516, 2015
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Part of Cancer Research, 2015
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Part of Scientific Reports, 2015
- DOI for In vitro discovery of promising anti-cancer drug combinations using iterative maximisation of a therapeutic index
- Download full text (pdf) of In vitro discovery of promising anti-cancer drug combinations using iterative maximisation of a therapeutic index
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A Machine Learning Approach to Explain Drug Selectivity to Soluble and Membrane Protein Targets
Part of Molecular Informatics, p. 44-52, 2015
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DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia
Part of Clinical Epigenetics, 2015
- DOI for DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia
- Download full text (pdf) of DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia
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Part of Journal of Biomolecular Screening, p. 372-381, 2015
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Translational Research in Complementary and Alternative Medicine 2014
Part of Evidence-based Complementary and Alternative Medicine, 2015
- DOI for Translational Research in Complementary and Alternative Medicine 2014
- Download full text (pdf) of Translational Research in Complementary and Alternative Medicine 2014
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Part of European Journal of Nutrition & Food Safety, p. 392-403, 2014
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Part of Autophagy, p. 57-69, 2014
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Part of Apoptosis (London), p. 1411-1418, 2014
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Part of Molecular Cancer Therapeutics, p. 1964-1976, 2014
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Part of Journal of chemical information and modeling, p. 3251-3258, 2014
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Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia
Part of Genome Biology, 2013
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Automated QuantMap for rapid quantitative molecular network topology analysis
Part of Bioinformatics, p. 2369-2370, 2013
- DOI for Automated QuantMap for rapid quantitative molecular network topology analysis
- Download full text (pdf) of Automated QuantMap for rapid quantitative molecular network topology analysis
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Part of BMC Cancer, p. 374, 2013
- DOI for Screening for phenotype selective activity in multidrug resistant cells identifies a novel tubulin active agent insensitive to common forms of cancer drug resistance
- Download full text (pdf) of Screening for phenotype selective activity in multidrug resistant cells identifies a novel tubulin active agent insensitive to common forms of cancer drug resistance
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Part of Algorithms for Molecular Biology, p. 2, 2012
- DOI for A strand specific high resolution normalization method for chip-sequencing data employing multiple experimental control measurements
- Download full text (pdf) of A strand specific high resolution normalization method for chip-sequencing data employing multiple experimental control measurements
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Digital gene expression profiling of primary acute lymphoblastic leukemia cells
Part of Leukemia, p. 1218-1227, 2012
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The DNA Methylation Landscape of Paediatric Acute Lymphoblastic Leukemia
Part of European Journal of Cancer, 2012
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Part of Resuscitation, p. 1381-1385, 2012
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Part of Journal of Chemical Information and Modeling, p. 1238-1249, 2012
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ProteinSeq: high-performance proteomic analyses by proximity ligation and next generation sequencing
Part of PLOS ONE, 2011
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Part of Proteins, p. 2595-2606, 2011
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Part of Food and Chemical Toxicology, p. 2830-2840, 2011
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Part of Molecular & Cellular Proteomics, 2011
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Part of Blood, p. 1214-1225, 2010
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Part of Artificial Intelligence in Medicine, p. 93-104, 2010
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Part of European Journal of Haematology, p. 22-34, 2009
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Part of Leukemia and Lymphoma, p. 2333-2343, 2008
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Cross-validation and bootstrapping are unreliable in small sample classification
Part of Pattern Recognition Letters, p. 1960-1965, 2008
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Part of BMC Systems Biology, p. 45, 2007
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EVALLER: a web server for in silico assessment of potential protein allergenicity
Part of Nucleic Acids Research, 2007
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Effective brain connectivity in social anxiety disorder: a Bayesian approach
Part of Biological Psychiatry, 2007
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Part of International Journal of Cancer, p. 189-195, 2007
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Part of Journal of Allergy and Clinical Immunology, p. 1433-1440, 2007
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In vitro drug sensitivity-gene expression correlations involve a tissue of origin dependency
Part of Journal of chemical information and modeling, p. 239-248, 2007
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Part of BMC Bioinformatics, p. 127, 2006
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Screening of an annotated compound library for drug activity in a resistant myeloma cell line
Part of Cancer Chemotherapy and Pharmacology, p. 749-758, 2006
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Part of Journal of Biomolecular Screening, p. 457-468, 2006
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Molecular markers for discrimination of benign and malignant follicular thyroid tumors
Part of Tumor Biology, p. 211-220, 2006
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Unbiased descriptor and parameter selection confirms the potential of proteochemometric modelling
Part of BMC Bioinformatics, p. 50, 2005
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Part of Proteins, p. 918-925, 2005
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Part of Bioinformatics, p. 39-50, 2005
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Part of British Journal of Cancer, p. 483-492, 2005
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Part of Journal of Chemical Information and Modeling, p. 1244-1255, 2005
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Structural modeling extends QSAR analysis of antibody-lysozyme interactions to 3D-QSAR
Part of Biophysical Journal, p. 2264-2272, 2003
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Prediction of food protein allergenicity: A bioinformatic learning systems approach
Part of Silico Biol 2, p. 525-534, 2002
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Part of Molecular Cancer Therapeutics
Articles, review/survey
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Quantitative Chemogenomics: Machine-Learning Models of Protein-Ligand Interaction
Part of Current Topics in Medicinal Chemistry, p. 1978-1993, 2011