Mats Gustafsson
Professor at Department of Civil and Industrial Engineering; Industrial Engineering and Management
- Telephone:
- +46 18 471 30 42
- Mobile phone:
- +46 73 469 79 83
- E-mail:
- mats.gustafsson@angstrom.uu.se
- Visiting address:
- Ångströmlaboratoriet, Lägerhyddsvägen 1
752 37 Uppsala - Postal address:
- Box 169
751 04 Uppsala
Professor at Department of Medical Sciences; Cancer Pharmacology and Computational Medicine
- Telephone:
- +46 18 611 42 41
- Mobile phone:
- +46 73 469 79 83
- Fax:
- +46 18 611 37 03
- E-mail:
- Mats.Gustafsson@medsci.uu.se
- Visiting address:
- Akademiska sjukhuset, ingång 61
- Postal address:
- Akademiska sjukhuset, ingång 61
751 85 Uppsala

Publications
Recent publications
Exhaustive in vitro evaluation of the 9-drug cocktail CUSP9 for treatment of glioblastoma
Part of Computers in Biology and Medicine, 2024
- DOI for Exhaustive in vitro evaluation of the 9-drug cocktail CUSP9 for treatment of glioblastoma
- Download full text (pdf) of Exhaustive in vitro evaluation of the 9-drug cocktail CUSP9 for treatment of glioblastoma
Part of PLOS ONE, 2020
- DOI for COMBSecretomics: a pragmatic methodological framework for higher-order drug combination analysis using secretomics
- Download full text (pdf) of COMBSecretomics: a pragmatic methodological framework for higher-order drug combination analysis using secretomics
A Novel Multiplex Based Platform for Osteoarthritis Drug Candidate Evaluation
Part of Annals of Biomedical Engineering, p. 2438-2448, 2020
Part of BMC Bioinformatics, 2019
- DOI for COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining
- Download full text (pdf) of COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining
Part of PLOS ONE, 2019
- DOI for An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns
- Download full text (pdf) of An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns
All publications
Articles in journal
Exhaustive in vitro evaluation of the 9-drug cocktail CUSP9 for treatment of glioblastoma
Part of Computers in Biology and Medicine, 2024
- DOI for Exhaustive in vitro evaluation of the 9-drug cocktail CUSP9 for treatment of glioblastoma
- Download full text (pdf) of Exhaustive in vitro evaluation of the 9-drug cocktail CUSP9 for treatment of glioblastoma
Part of PLOS ONE, 2020
- DOI for COMBSecretomics: a pragmatic methodological framework for higher-order drug combination analysis using secretomics
- Download full text (pdf) of COMBSecretomics: a pragmatic methodological framework for higher-order drug combination analysis using secretomics
A Novel Multiplex Based Platform for Osteoarthritis Drug Candidate Evaluation
Part of Annals of Biomedical Engineering, p. 2438-2448, 2020
Part of BMC Bioinformatics, 2019
- DOI for COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining
- Download full text (pdf) of COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining
Part of PLOS ONE, 2019
- DOI for An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns
- Download full text (pdf) of An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns
Investigations Of Cytokine Interplay With An In Vitro Model Of Osteoarthritis
Part of Osteoarthritis and Cartilage, 2018
Part of BMC Bioinformatics, 2018
- DOI for COMBImage: a modular parallel processing framework for pairwise drug combination analysis that quantifies temporal changes in label-free video microscopy movies
- Download full text (pdf) of COMBImage: a modular parallel processing framework for pairwise drug combination analysis that quantifies temporal changes in label-free video microscopy movies
Part of Journal of Statistical Software, p. 1-30, 2018
- DOI for Developer-Friendly and Computationally Efficient Predictive Modeling without Information Leakage: The emil Package for R
- Download full text (pdf) of Developer-Friendly and Computationally Efficient Predictive Modeling without Information Leakage: The emil Package for R
Part of Pattern Recognition, p. 133-143, 2018
Part of Leukemia Research, p. 41-46, 2017
- DOI for Towards repositioning of quinacrine for treatment of acute myeloid leukemia - Promising synergies and in vivo effects.
- Download full text (pdf) of Towards repositioning of quinacrine for treatment of acute myeloid leukemia - Promising synergies and in vivo effects.
Part of Oncotarget, p. 103952-103967, 2017
- DOI for Bliss and Loewe interaction analyses of clinically relevant drug combinations in human colon cancer cell lines reveal complex patterns of synergy and antagonism
- Download full text (pdf) of Bliss and Loewe interaction analyses of clinically relevant drug combinations in human colon cancer cell lines reveal complex patterns of synergy and antagonism
Part of Metabolomics, 2017
- DOI for Mass spectrometry based metabolomics for in vitro systems pharmacology: pitfalls, challenges, and computational solutions.
- Download full text (pdf) of Mass spectrometry based metabolomics for in vitro systems pharmacology: pitfalls, challenges, and computational solutions.
Targeting tumor cells based on Phosphodiesterase 3A expression
Part of Experimental Cell Research, p. 308-315, 2017
Part of Cell Reports, p. 2994-3009, 2016
- DOI for Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition
- Download full text (pdf) of Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition
Part of Scandinavian Journal of Rheumatology, p. 44-45, 2016
Part of PLOS ONE, 2016
- DOI for A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients
- Download full text (pdf) of A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients
Part of CELL CHEMICAL BIOLOGY, p. 1428-1438, 2016
Part of Biochemical Pharmacology, p. 40-49, 2016
Repositioning Of Quinacrine For Treatment Of Acute Myeloid Leukemia - Synergies And In Vivo Effects
Part of Haematologica, p. 367-368, 2016
Part of Chemometrics and Intelligent Laboratory Systems, p. 24-32, 2015
Part of Molecular Cancer Therapeutics, p. 1504-1516, 2015
Part of Cancer Research, 2015
Part of Scientific Reports, 2015
- DOI for In vitro discovery of promising anti-cancer drug combinations using iterative maximisation of a therapeutic index
- Download full text (pdf) of In vitro discovery of promising anti-cancer drug combinations using iterative maximisation of a therapeutic index
A Machine Learning Approach to Explain Drug Selectivity to Soluble and Membrane Protein Targets
Part of Molecular Informatics, p. 44-52, 2015
DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia
Part of Clinical Epigenetics, 2015
- DOI for DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia
- Download full text (pdf) of DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia
Part of Journal of Biomolecular Screening, p. 372-381, 2015
Translational Research in Complementary and Alternative Medicine 2014
Part of Evidence-based Complementary and Alternative Medicine, 2015
- DOI for Translational Research in Complementary and Alternative Medicine 2014
- Download full text (pdf) of Translational Research in Complementary and Alternative Medicine 2014
Part of European Journal of Nutrition & Food Safety, p. 392-403, 2014
Part of Autophagy, p. 57-69, 2014
Part of Apoptosis (London), p. 1411-1418, 2014
Part of Molecular Cancer Therapeutics, p. 1964-1976, 2014
Part of Journal of chemical information and modeling, p. 3251-3258, 2014
Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia
Part of Genome Biology, 2013
Automated QuantMap for rapid quantitative molecular network topology analysis
Part of Bioinformatics, p. 2369-2370, 2013
- DOI for Automated QuantMap for rapid quantitative molecular network topology analysis
- Download full text (pdf) of Automated QuantMap for rapid quantitative molecular network topology analysis
Part of BMC Cancer, p. 374, 2013
- DOI for Screening for phenotype selective activity in multidrug resistant cells identifies a novel tubulin active agent insensitive to common forms of cancer drug resistance
- Download full text (pdf) of Screening for phenotype selective activity in multidrug resistant cells identifies a novel tubulin active agent insensitive to common forms of cancer drug resistance
Part of Algorithms for Molecular Biology, p. 2, 2012
- DOI for A strand specific high resolution normalization method for chip-sequencing data employing multiple experimental control measurements
- Download full text (pdf) of A strand specific high resolution normalization method for chip-sequencing data employing multiple experimental control measurements
Digital gene expression profiling of primary acute lymphoblastic leukemia cells
Part of Leukemia, p. 1218-1227, 2012
The DNA Methylation Landscape of Paediatric Acute Lymphoblastic Leukemia
Part of European Journal of Cancer, 2012
Part of Resuscitation, p. 1381-1385, 2012
Part of Journal of Chemical Information and Modeling, p. 1238-1249, 2012
ProteinSeq: high-performance proteomic analyses by proximity ligation and next generation sequencing
Part of PLOS ONE, 2011
Part of Proteins, p. 2595-2606, 2011
Part of Food and Chemical Toxicology, p. 2830-2840, 2011
Part of Molecular & Cellular Proteomics, 2011
Part of Blood, p. 1214-1225, 2010
Part of Artificial Intelligence in Medicine, p. 93-104, 2010
Part of European Journal of Haematology, p. 22-34, 2009
Part of Leukemia and Lymphoma, p. 2333-2343, 2008
Cross-validation and bootstrapping are unreliable in small sample classification
Part of Pattern Recognition Letters, p. 1960-1965, 2008
Part of BMC Systems Biology, p. 45, 2007
EVALLER: a web server for in silico assessment of potential protein allergenicity
Part of Nucleic Acids Research, 2007
Effective brain connectivity in social anxiety disorder: a Bayesian approach
Part of Biological Psychiatry, 2007
Part of International Journal of Cancer, p. 189-195, 2007
Part of Journal of Allergy and Clinical Immunology, p. 1433-1440, 2007
In vitro drug sensitivity-gene expression correlations involve a tissue of origin dependency
Part of Journal of chemical information and modeling, p. 239-248, 2007
Part of BMC Bioinformatics, p. 127, 2006
Screening of an annotated compound library for drug activity in a resistant myeloma cell line
Part of Cancer Chemotherapy and Pharmacology, p. 749-758, 2006
Part of Journal of Biomolecular Screening, p. 457-468, 2006
Molecular markers for discrimination of benign and malignant follicular thyroid tumors
Part of Tumor Biology, p. 211-220, 2006
Unbiased descriptor and parameter selection confirms the potential of proteochemometric modelling
Part of BMC Bioinformatics, p. 50, 2005
Part of Proteins, p. 918-925, 2005
Part of Bioinformatics, p. 39-50, 2005
Part of British Journal of Cancer, p. 483-492, 2005
Part of Journal of Chemical Information and Modeling, p. 1244-1255, 2005
Structural modeling extends QSAR analysis of antibody-lysozyme interactions to 3D-QSAR
Part of Biophysical Journal, p. 2264-2272, 2003
Prediction of food protein allergenicity: A bioinformatic learning systems approach
Part of Silico Biol 2, p. 525-534, 2002
Part of Molecular Cancer Therapeutics
Articles, review/survey
Quantitative Chemogenomics: Machine-Learning Models of Protein-Ligand Interaction
Part of Current Topics in Medicinal Chemistry, p. 1978-1993, 2011