Lanekoff Group

Quantitative approaches for spatial metabolomics with isomer differentiation using surface sampling capillary electrophoresis mass spectrometry

Golubova, Anastasia; Lanekoff, Ingela

Part of Talanta, 2026

• DOI for Quantitative approaches for spatial metabolomics with isomer differentiation using surface sampling capillary electrophoresis mass spectrometry
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Multiplexed tandem mass spectrometry imaging enables large-scale isomer mapping and annotation in tissues

Sharma, Varun V.; Toth, Gabor; Martinis, Robert; Hansen, Cathrin E et al.

Part of Angewandte Chemie International Edition, 2026

• DOI for Multiplexed tandem mass spectrometry imaging enables large-scale isomer mapping and annotation in tissues
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Metabolomic signatures of SSRI exposure during neural differentiation and correlation of lysophosphatidylcholines with early symptoms of neurodevelopmental disorders

Arora, Abishek; Vacy, Kristina; Marques, Cátia; Degeratu, Mihai-Ovidiu et al.

Part of eBioMedicine, 2026

• DOI for Metabolomic signatures of SSRI exposure during neural differentiation and correlation of lysophosphatidylcholines with early symptoms of neurodevelopmental disorders
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CellMate-A Deep Learning-Assisted Single-Cell Data Processing Platform

Friedrich, Felix; Marques, Catia; Lanekoff, Ingela

Part of Analytical Chemistry, p. 5561-5569, 2026

• DOI for CellMate-A Deep Learning-Assisted Single-Cell Data Processing Platform
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Microglial 5-LOX-activating protein antagonism alleviates leukotriene-driven neuroinflammation

Konings, Julia; Mingneau, Fleur; Chornyi, Serhii; Hansen, Cathrin E. et al.

Part of Acta Neuropathologica, 2026

• DOI for Microglial 5-LOX-activating protein antagonism alleviates leukotriene-driven neuroinflammation
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Spatial metabolomics platform combining mass spectrometry imaging and in-depth chemical characterization with capillary electrophoresis

Mavroudakis, Leonidas; Golubova, Anastasia; Lanekoff, Ingela

Part of Talanta, 2025

• DOI for Spatial metabolomics platform combining mass spectrometry imaging and in-depth chemical characterization with capillary electrophoresis
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Spatial mapping of the AA-PGE₂-EP axis in multiple sclerosis lesions

Hansen, Cathrin E.; Konings, Julia; Toth, Gabor; Chornyi, Serhii et al.

Part of Acta Neuropathologica, 2025

• DOI for Spatial mapping of the AA-PGE₂-EP axis in multiple sclerosis lesions
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Multimodal mass spectrometry - Raman imaging reveals solvent dependent structural and chemical tissue alterations

Tóth, Gábor; Kryska, Adrianna; Sroka-Bartnicka, Anna; Lanekoff, Ingela

Part of Analytica Chimica Acta, 2025

• DOI for Multimodal mass spectrometry - Raman imaging reveals solvent dependent structural and chemical tissue alterations
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Standard Addition as a Method for Quantitative Mass Spectrometry Imaging

Davidová, Lucie; Lanekoff, Ingela

Part of Analytical Chemistry, p. 11572-11580, 2025

• DOI for Standard Addition as a Method for Quantitative Mass Spectrometry Imaging
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Online Direct Infusion Mass Spectrometry of Liquid-Liquid Extraction Phases for Metabolite and Lipid Profiling with the Direct Infusion Probe

Marques, Catia; Blaase, Lena; Lanekoff, Ingela

Part of Metabolites, 2024

• DOI for Online Direct Infusion Mass Spectrometry of Liquid-Liquid Extraction Phases for Metabolite and Lipid Profiling with the Direct Infusion Probe
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Interleukin-13 Treatment of Living Lung Tissue Model Alters the Metabolome and Proteome: A Nano-DESI MS Metabolomics and Shotgun Proteomics Study

Tóth, Gábor; Golubova, Anastasia; Falk, Alexander; Bergström Lind, Sara et al.

Part of International Journal of Molecular Sciences, 2024

• DOI for Interleukin-13 Treatment of Living Lung Tissue Model Alters the Metabolome and Proteome: A Nano-DESI MS Metabolomics and Shotgun Proteomics Study
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Enhancing isomer specificity in mass spectrometry by combining silver ion adduction and ion mobility

Sharma, Varun V.; De Chavez, Danjo; Slade, Susan E.; Lanekoff, Ingela

Part of Talanta Open, 2024

• DOI for Enhancing isomer specificity in mass spectrometry by combining silver ion adduction and ion mobility
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Ion-to-Image, i2i, a Mass Spectrometry Imaging Data Analysis Platform for Continuous Ionization Techniques

Lillja, Johan; Duncan, Kyle D.; Lanekoff, Ingela

Part of Analytical Chemistry, p. 11589-11595, 2023

• DOI for Ion-to-Image, i2i, a Mass Spectrometry Imaging Data Analysis Platform for Continuous Ionization Techniques
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Identification and Imaging of Prostaglandin Isomers Utilizing MS³ Product Ions and Silver Cationization

Mavroudakis, Leonidas; Lanekoff, Ingela

Part of Journal of the American Society for Mass Spectrometry, p. 2341-2349, 2023

• DOI for Identification and Imaging of Prostaglandin Isomers Utilizing MS³ Product Ions and Silver Cationization
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Ischemic Stroke Causes Disruptions in the Carnitine Shuttle System

Mavroudakis, Leonidas; Lanekoff, Ingela

Part of Metabolites, 2023

• DOI for Ischemic Stroke Causes Disruptions in the Carnitine Shuttle System
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Screening autism-associated environmental factors in differentiating human neural progenitors with fractional factorial design-based transcriptomics

Arora, Abishek; Becker, Martin; Marques-Santos, Cátia M.; Oksanen, Marika et al.

Part of Scientific Reports, 2023

• DOI for Screening autism-associated environmental factors in differentiating human neural progenitors with fractional factorial design-based transcriptomics
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Global and Spatial Metabolomics of Individual Cells Using a Tapered Pneumatically Assisted nano-DESI Probe

Marques-Santos, Cátia M.; Friedrich, Felix; Liu, Liangwen; Castoldi, Francesca et al.

Part of Journal of the American Society for Mass Spectrometry, p. 2518-2524, 2023

• DOI for Global and Spatial Metabolomics of Individual Cells Using a Tapered Pneumatically Assisted nano-DESI Probe
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Revealing Structure and Localization of Steroid Regioisomers through Predictive Fragmentation Patterns in Mass Spectrometry Imaging

Sharma, Varun; Lanekoff, Ingela

Part of Analytical Chemistry, p. 17843-17850, 2023

• DOI for Revealing Structure and Localization of Steroid Regioisomers through Predictive Fragmentation Patterns in Mass Spectrometry Imaging
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Matrix Effects Free Imaging of Thin Tissue Sections Using Pneumatically Assisted Nano-DESI MSI

Mavroudakis, Leonidas; Lanekoff, Ingela

Part of Imaging Mass Spectrometry, p. 107-121, Humana Press, 2023

• DOI for Matrix Effects Free Imaging of Thin Tissue Sections Using Pneumatically Assisted Nano-DESI MSI

Surface sampling capillary electrophoresis–mass spectrometry for a direct chemical characterization of tissue and blood samples

Golubova, Anastasia; Lanekoff, Ingela

Part of Electrophoresis, p. 387-394, 2023

• DOI for Surface sampling capillary electrophoresis–mass spectrometry for a direct chemical characterization of tissue and blood samples
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Quantitative determination of sn-positional phospholipid isomers in MSn using silver cationization

Lillja, Johan; Lanekoff, Ingela

Part of Analytical and Bioanalytical Chemistry, p. 7473-7482, 2022

• DOI for Quantitative determination of sn-positional phospholipid isomers in MSn using silver cationization
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Simultaneous determination of four organic acids in beverages by capillary electrophoresis coupled with ultraviolet detector

Bui Quang, Dong; Ivanova, Arina; Qiu, Siyuan; Lanekoff, Ingela

Part of Vietnam Journal of Food Control, p. 89-103, 2022

• DOI for Simultaneous determination of four organic acids in beverages by capillary electrophoresis coupled with ultraviolet detector

Host-Guest Chemistry for Simultaneous Imaging of Endogenous Alkali Metals and Metabolites with Mass Spectrometry

Mavroudakis, Leonidas; Duncan, Kyle D.; Lanekoff, Ingela

Part of Analytical Chemistry, p. 2391-2398, 2022

• DOI for Host-Guest Chemistry for Simultaneous Imaging of Endogenous Alkali Metals and Metabolites with Mass Spectrometry
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Membrane Sampling Separates Naphthenic Acids from Biogenic Dissolved Organic Matter for Direct Analysis by Mass Spectrometry

Duncan, Kyle D.; Hawkes, Jeffrey A.; Berg, Mykelti; Clarijs, Bas et al.

Part of Environmental Science and Technology, p. 3096-3105, 2022

• DOI for Membrane Sampling Separates Naphthenic Acids from Biogenic Dissolved Organic Matter for Direct Analysis by Mass Spectrometry

A Direct Infusion Probe for Rapid Metabolomics of Low-Volume Samples

Marques, Cátia; Liu, Liangwen; Duncan, Kyle D.; Lanekoff, Ingela

Part of Analytical Chemistry, p. 12875-12883, 2022

• DOI for A Direct Infusion Probe for Rapid Metabolomics of Low-Volume Samples
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Single-cell metabolomics: where are we and where are we going?

Lanekoff, Ingela; Sharma, Varun V.; Marques, Cátia

Part of Current Opinion in Biotechnology, 2022

• DOI for Single-cell metabolomics: where are we and where are we going?
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Single cell metabolism: current and future trends

Ali, Ahmed; Davidson, Shawn; Fraenkel, Ernest; Gilmore, Ian et al.

Part of Metabolomics, 2022

• DOI for Single cell metabolism: current and future trends

CpG preconditioning reduces accumulation of lysophosphatidylcholine in ischemic brain tissue after middle cerebral artery occlusion

Mavroudakis, Leonidas; Stevens, Susan; Duncan, Kyle D.; Stenzel-Poore, Mary et al.

Part of Analytical and Bioanalytical Chemistry, p. 2735-2745, 2021

• DOI for CpG preconditioning reduces accumulation of lysophosphatidylcholine in ischemic brain tissue after middle cerebral artery occlusion
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In situ imaging reveals disparity between prostaglandin localization and abundance of prostaglandin synthases

Duncan, Kyle D.; Sun, Xiaofei; Baker, Erin S.; Dey, Sudhansu K. et al.

Part of Communications Biology, 2021

• DOI for In situ imaging reveals disparity between prostaglandin localization and abundance of prostaglandin synthases
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State-of-the-art Capillary Electrophoresis Mass Spectrometry Methods for Analyzing the Polar Metabolome

Duncan, Kyle D.; Lanekoff, Ingela

Part of Advanced Mass Spectrometry-Based Analytical Separation Techniques for Probing the Polar Metabolome, p. 125-164, Royal Society of Chemistry, 2021

• DOI for State-of-the-art Capillary Electrophoresis Mass Spectrometry Methods for Analyzing the Polar Metabolome

PDMS leaching and its implications for on-chip studies focusing on bone regeneration applications

Carter, Sarah-Sophia; Atif, Abdul Raouf; Kadekar, Sandeep; Lanekoff, Ingela et al.

Part of Organs-on-a-Chip, 2020

• DOI for PDMS leaching and its implications for on-chip studies focusing on bone regeneration applications
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Determination of Monounsaturated Fatty Acid Isomers in Biological Systems by Modeling MS3 Product Ion Patterns

Lillja, Johan; Duncan, Kyle D.; Lanekoff, Ingela

Part of Journal of the American Society for Mass Spectrometry, p. 2479-2487, 2020

• DOI for Determination of Monounsaturated Fatty Acid Isomers in Biological Systems by Modeling MS3 Product Ion Patterns

Advances in mass spectrometry based single-cell metabolomics

Duncan, Kyle D.; Fyrestam, Jonas; Lanekoff, Ingela

Part of The Analyst, p. 782-793, 2019

• DOI for Advances in mass spectrometry based single-cell metabolomics

Statistical detection of differentially abundant ions in mass spectrometry-based imaging experiments with complex designs

Bemis, Kylie A.; Guo, Dan; Harry, April J.; Thomas, Mathew et al.

Part of International Journal of Mass Spectrometry, p. 49-57, 2019

• DOI for Statistical detection of differentially abundant ions in mass spectrometry-based imaging experiments with complex designs

Spatially Defined Surface Sampling Capillary Electrophoresis Mass Spectrometry

Duncan, Kyle D.; Lanekoff, Ingela

Part of Analytical Chemistry, p. 7819-7827, 2019

• DOI for Spatially Defined Surface Sampling Capillary Electrophoresis Mass Spectrometry

Metabolite aberrations in early diabetes detected in rat kidney using mass spectrometry imaging

Bergman, Hilde-Marlene; Lindfors, Lina; Palm, Fredrik; Kihlberg, Jan et al.

Part of Analytical and Bioanalytical Chemistry, p. 2809-2816, 2019

• DOI for Metabolite aberrations in early diabetes detected in rat kidney using mass spectrometry imaging
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Single‐Cell Mass Spectrometry

Bergman, Hilde-Marlene; Duncan, Kyle D.; Lanekoff, Ingela

Part of Encyclopedia of Analytical Chemistry, Wiley-VCH Verlagsgesellschaft, 2018

• DOI for Single‐Cell Mass Spectrometry

Improving the biocompatibility of PDMS by improving its curing time and temperature

Carter, Sarah-Sophia; Atif, Abdul Raouf M.; Lanekoff, Ingela; Tenje, Maria et al.

2018

Quantitative Mass Spectrometry Imaging of Molecules in Biological Systems

Lanekoff, Ingela; Laskin, Julia

Part of Advances In Chromatography, Vol 54, p. 43-72, CRC Press, 2018

• DOI for Quantitative Mass Spectrometry Imaging of Molecules in Biological Systems
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Oversampling To Improve Spatial Resolution for Liquid Extraction Mass Spectrometry Imaging

Duncan, Kyle D.; Andersson, Ingela

Part of Analytical Chemistry, p. 2451-2455, 2018

• DOI for Oversampling To Improve Spatial Resolution for Liquid Extraction Mass Spectrometry Imaging

Tailoring the biocompatibility of the elastomer PDMS for on-chip applications

Carter, Sarah-Sophia; Atif, Abdul Raouf; Lanekoff, Ingela; Tenje, Maria et al.

2018

Quantitative Mass Spectrometry Imaging of Prostaglandins as Silver Ion Adducts with Nanospray Desorption Electrospray Ionization

Duncan, Kyle D.; Fang, Ru; Yuan, Jia; Chu, Rosalie K. et al.

Part of Analytical Chemistry, p. 7246-7252, 2018

• DOI for Quantitative Mass Spectrometry Imaging of Prostaglandins as Silver Ion Adducts with Nanospray Desorption Electrospray Ionization

Profiling and quantifying endogenous molecules in single cells using nano-DESI MS

Bergman, Hilde-Marlene; Lanekoff, Ingela

Part of The Analyst, p. 3639-3647, 2017

• DOI for Profiling and quantifying endogenous molecules in single cells using nano-DESI MS

A pneumatically assisted nanospray desorption electrospray ionization source for increased solvent versatility and enhanced metabolite detection from tissue

Duncan, Kyle D.; Bergman, Hilde-Marlene; Andersson, Ingela

Part of The Analyst, p. 3424-3431, 2017

• DOI for A pneumatically assisted nanospray desorption electrospray ionization source for increased solvent versatility and enhanced metabolite detection from tissue

Direct Analysis of Pharmaceutical Drugs Using Nano-DESI MS

Cardoso-Palacios, Carlos; Lanekoff, Ingela

Part of Journal of Analytical Methods in Chemistry, 2016

• DOI for Direct Analysis of Pharmaceutical Drugs Using Nano-DESI MS

Quantitative mass spectrometry imaging of small-molecule neurotransmitters in rat brain tissue sections using nanospray desorption electrospray ionization

Bergman, Hilde-Marléne; Lundin, Erik; Andersson, Malin; Lanekoff, Ingela

Part of The Analyst, p. 3686-3695, 2016

• DOI for Quantitative mass spectrometry imaging of small-molecule neurotransmitters in rat brain tissue sections using nanospray desorption electrospray ionization

Ambient Mass Spectrometry Imaging Using Direct Liquid Extraction Techniques

Laskin, Julia; Andersson, Ingela

Part of Analytical Chemistry, p. 52-73, 2016

• DOI for Ambient Mass Spectrometry Imaging Using Direct Liquid Extraction Techniques

Trp53 deficient mice predisposed to preterm birth display region-specific lipid alterations at the embryo implantation site

Lanekoff, Ingela; Cha, Jeeyeon; Kyle, Jennifer E.; Dey, Sudhansu K. et al.

Part of Scientific Reports, 2016

• DOI for Trp53 deficient mice predisposed to preterm birth display region-specific lipid alterations at the embryo implantation site
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PACAP suppresses dry eye signs by stimulating tear secretion

Nakamachi, Tomoya; Ohtaki, Hirokazu; Seki, Tamotsu; Yofu, Sachiko et al.

Part of Nature Communications, 2016

• DOI for PACAP suppresses dry eye signs by stimulating tear secretion
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Three-dimensional imaging of lipids and metabolites in tissues by nanospray desorption electrospray ionization mass spectrometry

Lanekoff, Ingela; Burnum-Johnson, Kristin; Thomas, Mathew; Cha, Jeeyeon et al.

Part of Analytical and Bioanalytical Chemistry, p. 2063-2071, 2015

• DOI for Three-dimensional imaging of lipids and metabolites in tissues by nanospray desorption electrospray ionization mass spectrometry