Ingela Lanekoff
Professor at Department of Chemistry - BMC; Analytical Chemistry; Lanekoff group
- Telephone:
- +46 18 471 36 73
- E-mail:
- ingela.lanekoff@kemi.uu.se
- Visiting address:
- Husargatan 3 (D5)
752 37 Uppsala - Postal address:
- Box 599
75124 Uppsala
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Short presentation
The research within the Lanekoff-group is focused on developing and utilizing novel approaches for mass spectrometric analysis and imaging of lipids and metabolites from biological surfaces, such as thin tissue sections and cells.
Publications
Recent publications
- Interleukin-13 Treatment of Living Lung Tissue Model Alters the Metabolome and Proteome (2024)
- Screening autism-associated environmental factors in differentiating human neural progenitors with fractional factorial design-based transcriptomics (2023)
- Surface sampling capillary electrophoresis–mass spectrometry for a direct chemical characterization of tissue and blood samples (2023)
- Ion-to-Image, i2i, a Mass Spectrometry Imaging Data Analysis Platform for Continuous Ionization Techniques (2023)
- Global and Spatial Metabolomics of Individual Cells Using a Tapered Pneumatically Assisted nano-DESI Probe (2023)
All publications
Articles
- Interleukin-13 Treatment of Living Lung Tissue Model Alters the Metabolome and Proteome (2024)
- Screening autism-associated environmental factors in differentiating human neural progenitors with fractional factorial design-based transcriptomics (2023)
- Surface sampling capillary electrophoresis–mass spectrometry for a direct chemical characterization of tissue and blood samples (2023)
- Ion-to-Image, i2i, a Mass Spectrometry Imaging Data Analysis Platform for Continuous Ionization Techniques (2023)
- Global and Spatial Metabolomics of Individual Cells Using a Tapered Pneumatically Assisted nano-DESI Probe (2023)
- Identification and Imaging of Prostaglandin Isomers Utilizing MS3 Product Ions and Silver Cationization (2023)
- Ischemic Stroke Causes Disruptions in the Carnitine Shuttle System (2023)
- Revealing Structure and Localization of Steroid Regioisomers through Predictive Fragmentation Patterns in Mass Spectrometry Imaging (2023)
- Single cell metabolism (2022)
- Simultaneous determination of four organic acids in beverages by capillary electrophoresis coupled with ultraviolet detector (2022)
- Membrane Sampling Separates Naphthenic Acids from Biogenic Dissolved Organic Matter for Direct Analysis by Mass Spectrometry (2022)
- Single-cell metabolomics (2022)
- Quantitative determination of sn-positional phospholipid isomers in MSn using silver cationization (2022)
- A Direct Infusion Probe for Rapid Metabolomics of Low-Volume Samples (2022)
- Host-Guest Chemistry for Simultaneous Imaging of Endogenous Alkali Metals and Metabolites with Mass Spectrometry (2022)
- In situ imaging reveals disparity between prostaglandin localization and abundance of prostaglandin synthases (2021)
- CpG preconditioning reduces accumulation of lysophosphatidylcholine in ischemic brain tissue after middle cerebral artery occlusion (2021)
- PDMS leaching and its implications for on-chip studies focusing on bone regeneration applications (2020)
- Determination of Monounsaturated Fatty Acid Isomers in Biological Systems by Modeling MS3 Product Ion Patterns (2020)
- Statistical detection of differentially abundant ions in mass spectrometry-based imaging experiments with complex designs (2019)
- Metabolite aberrations in early diabetes detected in rat kidney using mass spectrometry imaging (2019)
- Advances in mass spectrometry based single-cell metabolomics (2019)
- Spatially Defined Surface Sampling Capillary Electrophoresis Mass Spectrometry (2019)
- Oversampling To Improve Spatial Resolution for Liquid Extraction Mass Spectrometry Imaging (2018)
- Quantitative Mass Spectrometry Imaging of Prostaglandins as Silver Ion Adducts with Nanospray Desorption Electrospray Ionization (2018)
- Profiling and quantifying endogenous molecules in single cells using nano-DESI MS (2017)
- A pneumatically assisted nanospray desorption electrospray ionization source for increased solvent versatility and enhanced metabolite detection from tissue (2017)
- Quantitative mass spectrometry imaging of small-molecule neurotransmitters in rat brain tissue sections using nanospray desorption electrospray ionization (2016)
- Direct Analysis of Pharmaceutical Drugs Using Nano-DESI MS (2016)
- Trp53 deficient mice predisposed to preterm birth display region-specific lipid alterations at the embryo implantation site (2016)
- Ambient Mass Spectrometry Imaging Using Direct Liquid Extraction Techniques (2016)
- PACAP suppresses dry eye signs by stimulating tear secretion (2016)
- Three-dimensional imaging of lipids and metabolites in tissues by nanospray desorption electrospray ionization mass spectrometry (2015)
- Towards Adaptive, Streaming Analysis of X-ray Tomography Data (2015)
- Matrix effects in biological mass spectrometry imaging (2014)
- Shotgun approach for quantitative imaging of phospholipids using nanospray desorption electrospray ionization mass spectrometry (2014)
- High-speed tandem mass spectrometric in situ imaging by nanospray desorption electrospray ionization mass spectrometry (2013)
- Spatially resolved analysis of glycolipids and metabolites in living Synechococcus sp. PCC 7002 using nanospray desorption electrospray ionization (2013)
- Mass spectrometry imaging of freeze-dried membrane phospholipids of dividing Tetrahymena pyriformis (2013)
- Imaging nicotine in rat brain tissue by use of nanospray desorption electrospray ionization mass spectrometry (2013)
- C60-ToF SIMS imaging of frozen hydrated HeLa cells (2013)
- Automated platform for high-resolution tissue imaging using nanospray desorption electrospray ionization mass spectrometry (2012)
- Study of electrochemical reactions using nanospray desorption electrospray ionization mass spectrometry (2012)
- An in situ fracture device to image lipids in single cells using ToF-SIMS (2011)
- Relative quantification of phospholipid accumulation in the PC12 cell plasma membrane following phospholipid incubation using TOF-SIMS imaging (2011)
- Analysis of intact ladderane phospholipids, originating from viable anammox bacteria, using RP-LC-ESI-MS (2010)
- Time of flight mass spectrometry imaging of samples fractured in situ with a spring-loaded trap system (2010)
- HAMLET interacts with lipid membranes and perturbs their structure and integrity. (2010)
- Ontogenetic development and spatial distribution of the ileal apical sodium-dependent bile acid transporter and the ileal lipid-binding protein in apoE knockout and C57BL/6 mice (2002)
- Detection of endogenous lipids and metabolites in single cells using nano-DESI
- Correlative image analysis for in-depth chemical analysis using multiple parallelized mass spectrometry imaging with high resolution and MSn
Chapters
- Single‐Cell Mass Spectrometry (2018)
- Quantitative Mass Spectrometry Imaging of Molecules in Biological Systems (2018)
- Imaging of lipids and metabolites using nanospray desorption electrospray ionization mass spectrometry. (2015)
Conferences
