Major advances in the treatment of type 1 diabetes
Recent decades have seen a lot of progress in diabetes treatment. In a new study, Per-Ola Carlsson, Professor of Medical Cell Biology, has obtained promising results. “This is the first time anyone has succeeded in transplanting insulin-producing cells into another individual without immunosuppressive drugs,” he says.
Faster drug development with AI
Can AI and automation shorten the time it takes to develop new drugs? Ola Spjuth combines his academic expertise in data-driven drug development with entrepreneurship to help the pharmaceutical industry capitalise on the potential of new technologies.
Global effort to introduce new antibiotics in healthcare
Multidrug-resistant bacteria are a growing problem, and new antibiotics are needed to continue to cure infectious diseases in the future. But how should new products be used to prevent bacteria from becoming resistant to them too? That is the focus of the INTRODUCE research project led by Thomas Tängdén, Senior Lecturer at the Department of Medical Sciences and infectious disease doctor at Uppsala University Hospital.
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The man rebuilding the body’s immune cells into cancer killers
Using the body’s own immune system to fight cancer: this is the essence of Magnus Essand’s research. This autumn he will start a clinical trial on patients with lymphoma, i.e. lymph node cancer, who do not respond to other treatments. Patients’ own T cells, a type of white blood cell, will be modified to recognise and kill cancer cells.
Cow slime can help disc herniation patients after surgery
Researchers at Uppsala University have developed a gel inspired by cow slime for patients suffering from disc herniation. By adding the mucin gel immediately after surgery, it is possible to create a protective barrier around the discs to prevent the immune system from attacking their nucleus pulposus. This keeps the discs intact and reduces the risk of further damage.
Basic research led to drug candidates for fatal lung disease
During the 1990s, medicinal chemist Anders Hallberg was working in his lab at the Department of Medicinal Chemistry. He was exploring a hormonal system in the body that regulates blood pressure among other things by designing different molecules. 30 years later, one of these molecules has been developed into a drug candidate to treat a severe and incurable disease, idiopathic pulmonary fibrosis, and is now being tested on patients in multiple countries.
Research breakthrough in fight against resistant bacteria
Researchers at Uppsala University have identified a new class of antibiotics with potent activity against the multi-drug resistant bacteria that WHO pinpoints as the most critical to develop novel treatments for. "That our compound can cure bloodstream infections in mice models indicates great potential," says Anders Karlén, Professor at the Department of Medicinal chemistry.
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Drug development
Research on preventing, treating, relieving and ultimately perhaps curing diseases and developing new therapies.
Global health
Basic medical research and clinical medicine engage with social science and behavioural science, law, natural sciences and technology.
Antibiotic resistance
Research in areas such as drug development, microbiology, diagnostics, new economic models, law and sustainable development.
Research
Pharmaceutical research at Uppsala University focuses on preventing, treating, relieving and ultimately perhaps curing diseases and developing new therapies that help people to survive sickness and live life to the full.
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