General provisions

The Master programme committee, medical faculty

Entry requirements

Accepted to the Erasmus Mundus master programme Innovative medicine.

Learning outcomes

After completing the course, the student should be able to

• formulate and process scientific questions theoretically and with laboratory techniques
• account for and evaluate current methods and techniques within the research field and also be able to apply some of them
• compile, analyse critically and evaluate research results and present these both orally and in writing
• be able to describe how to work with an ethical and scientific approach.

Content

The course treats methods to study the human genome and changes therein, but also deals with post-genomic methods for studies of molecular interactions. Example of methods that can be treated are: genotyping at monogenetic and complex diseases, identification and isolation and functional analysis of genes, advanced PCR techniques, detection of mutations, DNA/RNA/protein-based diagnostics, fluorescence in situ hybridisation (FISH). DNA techniques within diagnostics and forensic medicine are dealt with together with techniques for functional genome analysis, array technology for gene expression, comparative genomics, tissue expression and current methods for analysis of epigenetic regulatory mechanisms such as chromatin immunoprecipitation (ChIP). Furthermore, techniques and equipment for large-scale trials within genotyping and sequencing are treated.

Instruction

Instruction is provided in English in the form of lectures and mandatory seminars, laboratory exercises, computer

practicals and other theoretical and practical exercises such as problem-oriented exercises and presentations related to current research fields. A joint seminar series for Master programmes is included.

Assessment

Modules: Laboratory session 6 credits; Literature assignment 6 credits; Seminar 3 credits

The module Laboratory session requires completed laboratory practicals. The module Literature assignment is presented orally and in written form. The seminars require active participation.

If there are special reasons for doing so, an examiner may make an exception from the method of assessment indicated and allow a student to be assessed by another method. An example of special reasons might be a certificate regarding special pedagogical support from the University's disability coordinator.