Publications

Fibrillarin-dependent 2′-O-methylation modulates RPS28 ribosome incorporation and oncogenic translation

Groza, Paula; Kumari, Kanchan; Esteva-Socias, Margalida; Schott, Johanna et al.

Part of Cancer Letters, 2026

• DOI for Fibrillarin-dependent 2′-O-methylation modulates RPS28 ribosome incorporation and oncogenic translation
• Download full text (pdf) of Fibrillarin-dependent 2′-O-methylation modulates RPS28 ribosome incorporation and oncogenic translation

Quantitative approaches for spatial metabolomics with isomer differentiation using surface sampling capillary electrophoresis mass spectrometry

Golubova, Anastasia; Lanekoff, Ingela

Part of Talanta, 2026

• DOI for Quantitative approaches for spatial metabolomics with isomer differentiation using surface sampling capillary electrophoresis mass spectrometry
• Download full text (pdf) of Quantitative approaches for spatial metabolomics with isomer differentiation using surface sampling capillary electrophoresis mass spectrometry

Targeted NMR signal enhancement of RNA by site-directed bis-nitroxide labeling

Dasgupta, Rubin; Steinmetzger, Christian; Wilson, Ancy T.; Chatterjee, Satyaki et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2026

• DOI for Targeted NMR signal enhancement of RNA by site-directed bis-nitroxide labeling

¹H R_1ρ relaxation identifies a hidden intermediate in DNA base-pairing

Dasgupta, Rubin; Steinmetzger, Christian; Ilgen, Julian; Petzold, Katja

Part of Nature Communications, 2026

• DOI for ¹H R_1ρ relaxation identifies a hidden intermediate in DNA base-pairing
• Download full text (pdf) of ¹H R_1ρ relaxation identifies a hidden intermediate in DNA base-pairing

Multiplexed tandem mass spectrometry imaging enables large-scale isomer mapping and annotation in tissues

Sharma, Varun V.; Toth, Gabor; Martinis, Robert; Hansen, Cathrin E et al.

Part of Angewandte Chemie International Edition, 2026

• DOI for Multiplexed tandem mass spectrometry imaging enables large-scale isomer mapping and annotation in tissues
• Download full text (pdf) of Multiplexed tandem mass spectrometry imaging enables large-scale isomer mapping and annotation in tissues

Conformational Trajectory of the Molecular Chameleon Grazoprevir from Formulation to Target-Bound

Wieske, Lianne H. E.; Bu, Guanhong; Erdélyi, Máté; Kihlberg, Jan et al.

Part of Chemistry - A European Journal, 2026

• DOI for Conformational Trajectory of the Molecular Chameleon Grazoprevir from Formulation to Target-Bound
• Download full text (pdf) of Conformational Trajectory of the Molecular Chameleon Grazoprevir from Formulation to Target-Bound

Probing Weak Halogen Bonding in Aqueous Solution

Herbst, Manuel; Wu, Leyun; Woordes, Yannik T.; Peintner, Stefan et al.

Part of Journal of the American Chemical Society, p. 19331-19340, 2026

• DOI for Probing Weak Halogen Bonding in Aqueous Solution
• Download full text (pdf) of Probing Weak Halogen Bonding in Aqueous Solution

Metabolomic signatures of SSRI exposure during neural differentiation and correlation of lysophosphatidylcholines with early symptoms of neurodevelopmental disorders

Arora, Abishek; Vacy, Kristina; Marques, Cátia; Degeratu, Mihai-Ovidiu et al.

Part of eBioMedicine, 2026

• DOI for Metabolomic signatures of SSRI exposure during neural differentiation and correlation of lysophosphatidylcholines with early symptoms of neurodevelopmental disorders
• Download full text (pdf) of Metabolomic signatures of SSRI exposure during neural differentiation and correlation of lysophosphatidylcholines with early symptoms of neurodevelopmental disorders

RNA circularization preserves dynamics and enables in-cell relaxation NMR

Annecke, Henry T.P.; Bekcic, Katja; Toews, Sabrina; Feyrer, Hannes et al.

Part of Nucleic Acids Research, 2026

• DOI for RNA circularization preserves dynamics and enables in-cell relaxation NMR
• Download full text (pdf) of RNA circularization preserves dynamics and enables in-cell relaxation NMR

CellMate-A Deep Learning-Assisted Single-Cell Data Processing Platform

Friedrich, Felix; Marques, Catia; Lanekoff, Ingela

Part of Analytical Chemistry, p. 5561-5569, 2026

• DOI for CellMate-A Deep Learning-Assisted Single-Cell Data Processing Platform
• Download full text (pdf) of CellMate-A Deep Learning-Assisted Single-Cell Data Processing Platform

Microglial 5-LOX-activating protein antagonism alleviates leukotriene-driven neuroinflammation

Konings, Julia; Mingneau, Fleur; Chornyi, Serhii; Hansen, Cathrin E. et al.

Part of Acta Neuropathologica, 2026

• DOI for Microglial 5-LOX-activating protein antagonism alleviates leukotriene-driven neuroinflammation
• Download full text (pdf) of Microglial 5-LOX-activating protein antagonism alleviates leukotriene-driven neuroinflammation

Pulse Programme Considerations for Quantitative NOE Analysis

Wieske, Lianne H. E.; Lygnugaryté, Gintaré; Erdélyi, Máté

Part of Magnetic Resonance in Chemistry, p. 873-889, 2026

• DOI for Pulse Programme Considerations for Quantitative NOE Analysis
• Download full text (pdf) of Pulse Programme Considerations for Quantitative NOE Analysis

Spatial metabolomics platform combining mass spectrometry imaging and in-depth chemical characterization with capillary electrophoresis

Mavroudakis, Leonidas; Golubova, Anastasia; Lanekoff, Ingela

Part of Talanta, 2025

• DOI for Spatial metabolomics platform combining mass spectrometry imaging and in-depth chemical characterization with capillary electrophoresis
• Download full text (pdf) of Spatial metabolomics platform combining mass spectrometry imaging and in-depth chemical characterization with capillary electrophoresis

Refolding of the Deinococcus Radiodurans phytochrome photosensory module and backbone resonance assignment by solution NMR

Vrhovac, Lidija; Levkovets, Maria; Orekhov, Vladislav; Westenhoff, Sebastian

Part of Protein Expression and Purification, 2025

• DOI for Refolding of the Deinococcus Radiodurans phytochrome photosensory module and backbone resonance assignment by solution NMR
• Download full text (pdf) of Refolding of the Deinococcus Radiodurans phytochrome photosensory module and backbone resonance assignment by solution NMR

Spatial mapping of the AA-PGE₂-EP axis in multiple sclerosis lesions

Hansen, Cathrin E.; Konings, Julia; Toth, Gabor; Chornyi, Serhii et al.

Part of Acta Neuropathologica, 2025

• DOI for Spatial mapping of the AA-PGE₂-EP axis in multiple sclerosis lesions
• Download full text (pdf) of Spatial mapping of the AA-PGE₂-EP axis in multiple sclerosis lesions

Flavonoids from the leaves of Monanthotaxis filipes modulate PCSK9 and LDLR

Mayeka, James G.; Atilaw, Yoseph; Shadrack, Daniel M.; Sarnyai, Farkas et al.

Part of Scientific African, 2025

• DOI for Flavonoids from the leaves of Monanthotaxis filipes modulate PCSK9 and LDLR
• Download full text (pdf) of Flavonoids from the leaves of Monanthotaxis filipes modulate PCSK9 and LDLR

Linker-Determined Folding and Hydrophobic Interactions Explain a Major Difference in PROTAC Cell Permeability

Poongavanam, Vasanthanathan; Peintner, Stefan; Abeje, Yordanos; Kölling, Florian et al.

Part of ACS Medicinal Chemistry Letters, p. 681-687, 2025

• DOI for Linker-Determined Folding and Hydrophobic Interactions Explain a Major Difference in PROTAC Cell Permeability
• Download full text (pdf) of Linker-Determined Folding and Hydrophobic Interactions Explain a Major Difference in PROTAC Cell Permeability

Mapping effective microRNA pairing beyond the seed using abasic modifications

Kosek, David; Petzold, Katja; Andersson, Emma R.

Part of Nucleic Acids Research, 2025

• DOI for Mapping effective microRNA pairing beyond the seed using abasic modifications
• Download full text (pdf) of Mapping effective microRNA pairing beyond the seed using abasic modifications

Click chemistry-based bioconjugation of iron oxide nanoparticles

Asad, Shno; Ahl, David; Suárez-López, Yael del Carmen; Erdélyi, Máté et al.

Part of Small, 2025

• DOI for Click chemistry-based bioconjugation of iron oxide nanoparticles
• Download full text (pdf) of Click chemistry-based bioconjugation of iron oxide nanoparticles

Observation of early events in the photoactivation of Myxobacterial phytochrome using time-resolved serial femtosecond crystallography

Malla, Tek Narsingh; Aldama, Luis; Leon, Viridiana; Feliz, Denisse et al.

Part of Communications Chemistry, 2025

• DOI for Observation of early events in the photoactivation of Myxobacterial phytochrome using time-resolved serial femtosecond crystallography
• Download full text (pdf) of Observation of early events in the photoactivation of Myxobacterial phytochrome using time-resolved serial femtosecond crystallography

Multimodal mass spectrometry - Raman imaging reveals solvent dependent structural and chemical tissue alterations

Tóth, Gábor; Kryska, Adrianna; Sroka-Bartnicka, Anna; Lanekoff, Ingela

Part of Analytica Chimica Acta, 2025

• DOI for Multimodal mass spectrometry - Raman imaging reveals solvent dependent structural and chemical tissue alterations
• Download full text (pdf) of Multimodal mass spectrometry - Raman imaging reveals solvent dependent structural and chemical tissue alterations

Non-Uniform Sampling for Quantitative NOESY

Darling, William T. P.; Hyberts, Sven G.; Erdélyi, Máté

Part of Magnetic Resonance in Chemistry, p. 495-507, 2025

• DOI for Non-Uniform Sampling for Quantitative NOESY
• Download full text (pdf) of Non-Uniform Sampling for Quantitative NOESY

Sequence, structure, and affinity of miR-34a binding sites determine repression efficacy

Sweetapple, Lara; Kosek, David; Banijamali, Elnaz; Becker, Walter et al.

Part of Nucleic Acids Research, 2025

• DOI for Sequence, structure, and affinity of miR-34a binding sites determine repression efficacy
• Download full text (pdf) of Sequence, structure, and affinity of miR-34a binding sites determine repression efficacy

Standard Addition as a Method for Quantitative Mass Spectrometry Imaging

Davidová, Lucie; Lanekoff, Ingela

Part of Analytical Chemistry, p. 11572-11580, 2025

• DOI for Standard Addition as a Method for Quantitative Mass Spectrometry Imaging
• Download full text (pdf) of Standard Addition as a Method for Quantitative Mass Spectrometry Imaging

Hydrogen Bond-Induced Binding between Organofluorine and Protein via Fluorine Atoms: A Database Survey and Quantum Chemistry Calculation Study

Han, Zijian; Li, Jintian; Liao, Qingyi; Luo, Ruitong et al.

Part of Journal of Medicinal Chemistry, p. 14882-14894, 2025

• DOI for Hydrogen Bond-Induced Binding between Organofluorine and Protein via Fluorine Atoms: A Database Survey and Quantum Chemistry Calculation Study

Bioactive 2-arylbenzofuran and chalcone derivatives from Morus mesozygia Stapf

Matundura, Jackson Obegi; Mollel, Jackson T.; Miah, Masum; Said, Joanna et al.

Part of Fitoterapia, 2025

• DOI for Bioactive 2-arylbenzofuran and chalcone derivatives from Morus mesozygia Stapf
• Download full text (pdf) of Bioactive 2-arylbenzofuran and chalcone derivatives from Morus mesozygia Stapf

Ultrafast, remote-controlled protonation reaction enables structural changes in a phytochrome

Shankar, Madan Kumar; Grunewald, Lukas; Wahlgren, Weixiao Yuan; Stucki-Buchli, Brigitte et al.

Part of Science Advances, 2025

• DOI for Ultrafast, remote-controlled protonation reaction enables structural changes in a phytochrome
• Download full text (pdf) of Ultrafast, remote-controlled protonation reaction enables structural changes in a phytochrome

A Base‐Mediated Rearrangement of the Benzylic 1,5‐Hexadipyridynyl Moiety

Remmerswaal, Wouter A.; Nguyen, Thai‐Tony; Han, Zijian; Krasovski Slobodian, Fedor et al.

Part of ChemPlusChem, 2025

• DOI for A Base‐Mediated Rearrangement of the Benzylic 1,5‐Hexadipyridynyl Moiety
• Download full text (pdf) of A Base‐Mediated Rearrangement of the Benzylic 1,5‐Hexadipyridynyl Moiety

Chemical Mechanism of Allosteric and Asymmetric Dark Reversion in a Bacterial Phytochrome Uncovered by Cryo-EM

Bódizs, Szabolcs; Fischer, Anna-Lena M.; Cervenak, Miklós; Prodhan, Sayan et al.

Part of Journal of the American Chemical Society, p. 45701-45711, 2025

• DOI for Chemical Mechanism of Allosteric and Asymmetric Dark Reversion in a Bacterial Phytochrome Uncovered by Cryo-EM

Detection of a hybrid PrPfr state in the dark reversion of a bathy phytochrome indicates inter-dimer allostery

Prodhan, Sayan; Mészáros, Petra; Bódizs, Szabolcs; Zhou, Yalin et al.

Part of Physical Chemistry, Chemical Physics - PCCP, p. 20279-20287, 2025

• DOI for Detection of a hybrid PrPfr state in the dark reversion of a bathy phytochrome indicates inter-dimer allostery
• Download full text (pdf) of Detection of a hybrid PrPfr state in the dark reversion of a bathy phytochrome indicates inter-dimer allostery

Cryo-EM exposes diverse polymorphism in IAPP mutants to guide the rational design of peptide-based therapeutics

Ooi, Saik Ann; Valli, Dylan; Kuska, Mikolaj I.; Mari, Helena et al.

Part of Journal of Molecular Biology, 2025

• DOI for Cryo-EM exposes diverse polymorphism in IAPP mutants to guide the rational design of peptide-based therapeutics
• Download full text (pdf) of Cryo-EM exposes diverse polymorphism in IAPP mutants to guide the rational design of peptide-based therapeutics

Dynamically chiral phosphonic acid-type metallo-β-lactamase inhibitors

Gulyás, Kinga; Zhou, Liping; Salamonsen, Daniel; Prester, Andreas et al.

Part of Communications Chemistry, 2025

• DOI for Dynamically chiral phosphonic acid-type metallo-β-lactamase inhibitors
• Download full text (pdf) of Dynamically chiral phosphonic acid-type metallo-β-lactamase inhibitors

Time-resolved serial crystallography to reveal protein structural changes

Mészáros, Petra; Westenhoff, Sebastian

Part of Trends in Biochemical Sciences (TIBS), p. 183-184, 2024

• DOI for Time-resolved serial crystallography to reveal protein structural changes
• Download full text (pdf) of Time-resolved serial crystallography to reveal protein structural changes

Exploring the chemical space of orally bioavailable PROTACs

Apprato, Giulia; Poongavanam, Vasanthanathan; Jimenez, Diego Garcia; Atilaw, Yoseph et al.

Part of Drug Discovery Today, 2024

• DOI for Exploring the chemical space of orally bioavailable PROTACs
• Download full text (pdf) of Exploring the chemical space of orally bioavailable PROTACs

Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography

Cellini, Andrea; Shankar, Madan Kumar; Nimmrich, Amke; Hunt, Leigh Anna et al.

Part of Nature Chemistry, p. 624-632, 2024

• DOI for Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography
• Download full text (pdf) of Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography

Bioactive abietenolide diterpenes from Suregada procera

Matundura, Jackson Obegi; Mollel, Jackson T.; Miah, Masum; Said, Joanna et al.

Part of Fitoterapia, 2024

• DOI for Bioactive abietenolide diterpenes from Suregada procera
• Download full text (pdf) of Bioactive abietenolide diterpenes from Suregada procera

Antimicrobial Dihydroflavonols and Isoflavans Isolated from the Root Bark of Dalbergia gloveri

Kiganda, Ivan; Wieske, Lianne H. E.; Nchiozem-Ngnitedem, Vaderament-Alexe; Chalo, Duncan et al.

Part of Journal of Natural Products, p. 2263-2271, 2024

• DOI for Antimicrobial Dihydroflavonols and Isoflavans Isolated from the Root Bark of Dalbergia gloveri
• Download full text (pdf) of Antimicrobial Dihydroflavonols and Isoflavans Isolated from the Root Bark of Dalbergia gloveri

Elucidating the Binding Mode of Sulfur- and Selenium-Based Cationic Chalcogen-Bond Donors

Akbaba, Sercan; Steinke, Tim; Vogel, Lukas; Engelage, Elric et al.

Part of Chemistry - A European Journal, 2024

• DOI for Elucidating the Binding Mode of Sulfur- and Selenium-Based Cationic Chalcogen-Bond Donors
• Download full text (pdf) of Elucidating the Binding Mode of Sulfur- and Selenium-Based Cationic Chalcogen-Bond Donors

Antiviral Rotenoids and Isoflavones Isolated from Millettia oblata ssp. teitensis

Kiganda, Ivan; Bogaerts, Jonathan; Wieske, Lianne H.E.; Deyou, Tsegaye et al.

Part of Journal of Natural Products, p. 1003-1012, 2024

• DOI for Antiviral Rotenoids and Isoflavones Isolated from Millettia oblata ssp. teitensis
• Download full text (pdf) of Antiviral Rotenoids and Isoflavones Isolated from Millettia oblata ssp. teitensis

The Influence of Disulfide, Thioacetal and Lanthionine-Bridges on the Conformation of a Macrocyclic Peptide

Darling, William T. P.; Wieske, Hermina H. E.; Cook, Declan T.; Aliev, Abil E. et al.

Part of Chemistry - A European Journal, 2024

• DOI for The Influence of Disulfide, Thioacetal and Lanthionine-Bridges on the Conformation of a Macrocyclic Peptide
• Download full text (pdf) of The Influence of Disulfide, Thioacetal and Lanthionine-Bridges on the Conformation of a Macrocyclic Peptide

Online Direct Infusion Mass Spectrometry of Liquid-Liquid Extraction Phases for Metabolite and Lipid Profiling with the Direct Infusion Probe

Marques, Catia; Blaase, Lena; Lanekoff, Ingela

Part of Metabolites, 2024

• DOI for Online Direct Infusion Mass Spectrometry of Liquid-Liquid Extraction Phases for Metabolite and Lipid Profiling with the Direct Infusion Probe
• Download full text (pdf) of Online Direct Infusion Mass Spectrometry of Liquid-Liquid Extraction Phases for Metabolite and Lipid Profiling with the Direct Infusion Probe

Taming Molecular Folding: Anion-Templated Foldamers with Tunable Quaternary Structures

John, Eric A.; Riel, Asia Marie S.; Wieske, Lianne H. E.; Ray, Debmalya et al.

Part of Journal of the American Chemical Society, p. 16419-16427, 2024

• DOI for Taming Molecular Folding: Anion-Templated Foldamers with Tunable Quaternary Structures

Elucidating microRNA-34a organisation within human Argonaute-2 by dynamic nuclear polarisation-enhanced magic angle spinning NMR

Dasgupta, Rubin; Becker, Walter; Petzold, Katja

Part of Nucleic Acids Research, p. 11995-12004, 2024

• DOI for Elucidating microRNA-34a organisation within human Argonaute-2 by dynamic nuclear polarisation-enhanced magic angle spinning NMR
• Download full text (pdf) of Elucidating microRNA-34a organisation within human Argonaute-2 by dynamic nuclear polarisation-enhanced magic angle spinning NMR

Fluorinated captopril analogues inhibit metallo-ll-lactamases and facilitate structure determination of NDM-1 binding pose

Kondratieva, Alexandra; Palica, Katarzyna; Frohlich, Christopher; Hovd, Rebekka Rolfsnes et al.

Part of European Journal of Medicinal Chemistry, 2024

• DOI for Fluorinated captopril analogues inhibit metallo-ll-lactamases and facilitate structure determination of NDM-1 binding pose
• Download full text (pdf) of Fluorinated captopril analogues inhibit metallo-ll-lactamases and facilitate structure determination of NDM-1 binding pose

Interleukin-13 Treatment of Living Lung Tissue Model Alters the Metabolome and Proteome: A Nano-DESI MS Metabolomics and Shotgun Proteomics Study

Tóth, Gábor; Golubova, Anastasia; Falk, Alexander; Bergström Lind, Sara et al.

Part of International Journal of Molecular Sciences, 2024

• DOI for Interleukin-13 Treatment of Living Lung Tissue Model Alters the Metabolome and Proteome: A Nano-DESI MS Metabolomics and Shotgun Proteomics Study
• Download full text (pdf) of Interleukin-13 Treatment of Living Lung Tissue Model Alters the Metabolome and Proteome: A Nano-DESI MS Metabolomics and Shotgun Proteomics Study

Is Simultaneous Binding to DNA and Gyrase Important for the Antibacterial Activity of Cystobactamids?

Solga, Danny; Wieske, Hermina; Wilcox, Scott; Zeilinger, Carsten et al.

Part of Chemistry - A European Journal, 2024

• DOI for Is Simultaneous Binding to DNA and Gyrase Important for the Antibacterial Activity of Cystobactamids?
• Download full text (pdf) of Is Simultaneous Binding to DNA and Gyrase Important for the Antibacterial Activity of Cystobactamids?

Molecular chameleons in drug discovery

Poongavanam, Vasanthanathan; Wieske, Lianne H. E.; Peintner, Stefan; Erdélyi, Máté et al.

Part of Nature Reviews Chemistry, p. 45-60, 2024

• DOI for Molecular chameleons in drug discovery

Investigating Interaction Dynamics of an Enantioselective Peptide‐Catalyzed Acylation Reaction

Brauser, Matthias; Petzold, Katja; Thiele, Christina M.

Part of Angewandte Chemie International Edition, 2024

• DOI for Investigating Interaction Dynamics of an Enantioselective Peptide‐Catalyzed Acylation Reaction
• Download full text (pdf) of Investigating Interaction Dynamics of an Enantioselective Peptide‐Catalyzed Acylation Reaction

Optimising in-cell NMR acquisition for nucleic acids

Annecke, Henry T. P.; Eidelpes, Reiner; Feyrer, Hannes; Ilgen, Julian et al.

Part of Journal of Biomolecular NMR, p. 249-264, 2024

• DOI for Optimising in-cell NMR acquisition for nucleic acids
• Download full text (pdf) of Optimising in-cell NMR acquisition for nucleic acids

Impact of Linker Composition on VHL PROTAC Cell Permeability

Abeje, Yordanos Esubalew; Wieske, Hermina H. E.; Poongavanam, Vasanthanathan; Maassen, Stefanie et al.

Part of Journal of Medicinal Chemistry, p. 638-657, 2024

• DOI for Impact of Linker Composition on VHL PROTAC Cell Permeability
• Download full text (pdf) of Impact of Linker Composition on VHL PROTAC Cell Permeability