Ulf Bondesson

Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control

Nilsson Broberg, Malin; Knych, Heather; Bondesson, Ulf; Pettersson, Curt et al.

Part of Journal of Pharmaceutical and Biomedical Analysis, 2023

• DOI for Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control
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A multivariate data analysis approach for the investigation of in vitro derived metabolites of ACP-105 in comparison with human in vivo metabolites

Nilsson Broberg, Malin; Tillgren Ohlsson, Rebecca; Bondesson, Ulf; Pettersson, Curt et al.

Part of Journal of chromatography. B, 2023

• DOI for A multivariate data analysis approach for the investigation of in vitro derived metabolites of ACP-105 in comparison with human in vivo metabolites
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Concentration of carprofen in the milk of lactating bitches after cesarean section and during inflammatory conditions

Ferrari, Desiree; Lundgren, Sandra; Holmberg, Johanna; Edner, Anna et al.

Part of Theriogenology, p. 59-68, 2022

• DOI for Concentration of carprofen in the milk of lactating bitches after cesarean section and during inflammatory conditions

Investigation of Equine In Vivo and In Vitro Derived Metabolites of the Selective Androgen Receptor Modulator (SARM) ACP-105 for Improved Doping Control

Nilsson Broberg, Malin; Knych, Heather; Bondesson, Ulf; Pettersson, Curt et al.

Part of Metabolites, 2021

• DOI for Investigation of Equine In Vivo and In Vitro Derived Metabolites of the Selective Androgen Receptor Modulator (SARM) ACP-105 for Improved Doping Control
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Dimethylarginines correlate to common carotid artery wall layer dimensions and cardiovascular risk factors in pregnant women with/without preeclampsia: A group comparative study

Akhter, Tansim; Wikström, Gerhard; Larsson, Marita; Bondesson, Ulf et al.

Part of European Journal of Obstetrics, Gynecology, and Reproductive Biology, p. 288-293, 2021

• DOI for Dimethylarginines correlate to common carotid artery wall layer dimensions and cardiovascular risk factors in pregnant women with/without preeclampsia: A group comparative study
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Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control

Nilsson Broberg, Malin; Knych, Heather; Bondesson, Ulf; Pettersson, Curt et al.

Part of Journal of Pharmaceutical and Biomedical Analysis, 2023

• DOI for Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control
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A multivariate data analysis approach for the investigation of in vitro derived metabolites of ACP-105 in comparison with human in vivo metabolites

Nilsson Broberg, Malin; Tillgren Ohlsson, Rebecca; Bondesson, Ulf; Pettersson, Curt et al.

Part of Journal of chromatography. B, 2023

• DOI for A multivariate data analysis approach for the investigation of in vitro derived metabolites of ACP-105 in comparison with human in vivo metabolites
• Download full text (pdf) of A multivariate data analysis approach for the investigation of in vitro derived metabolites of ACP-105 in comparison with human in vivo metabolites

Concentration of carprofen in the milk of lactating bitches after cesarean section and during inflammatory conditions

Ferrari, Desiree; Lundgren, Sandra; Holmberg, Johanna; Edner, Anna et al.

Part of Theriogenology, p. 59-68, 2022

• DOI for Concentration of carprofen in the milk of lactating bitches after cesarean section and during inflammatory conditions

Investigation of Equine In Vivo and In Vitro Derived Metabolites of the Selective Androgen Receptor Modulator (SARM) ACP-105 for Improved Doping Control

Nilsson Broberg, Malin; Knych, Heather; Bondesson, Ulf; Pettersson, Curt et al.

Part of Metabolites, 2021

• DOI for Investigation of Equine In Vivo and In Vitro Derived Metabolites of the Selective Androgen Receptor Modulator (SARM) ACP-105 for Improved Doping Control
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Dimethylarginines correlate to common carotid artery wall layer dimensions and cardiovascular risk factors in pregnant women with/without preeclampsia: A group comparative study

Akhter, Tansim; Wikström, Gerhard; Larsson, Marita; Bondesson, Ulf et al.

Part of European Journal of Obstetrics, Gynecology, and Reproductive Biology, p. 288-293, 2021

• DOI for Dimethylarginines correlate to common carotid artery wall layer dimensions and cardiovascular risk factors in pregnant women with/without preeclampsia: A group comparative study
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Topical ophthalmic atropine in horses, pharmacokinetics and effect on intestinal motility

Strom, L.; Dalin, F.; Domberg, M.; Stenlund, C. et al.

Part of BMC Veterinary Research, 2021

• DOI for Topical ophthalmic atropine in horses, pharmacokinetics and effect on intestinal motility
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Bioavailability of subcutaneous and intramuscular administrated buprenorphine in New Zealand White rabbits

Askar, Raad; Fredriksson, Elin; Manell, Elin; Hedeland, Mikael et al.

Part of BMC Veterinary Research, 2020

• DOI for Bioavailability of subcutaneous and intramuscular administrated buprenorphine in New Zealand White rabbits
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Disposition and effect of intra-articularly administered dexamethasone on lipopolysaccharide induced equine synovitis

Ekstrand, Carl; Bondesson, Ulf; Giving, Ellen; Hedeland, Mikael et al.

Part of Acta Veterinaria Scandinavica, 2019

• DOI for Disposition and effect of intra-articularly administered dexamethasone on lipopolysaccharide induced equine synovitis
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Plasma l-arginine levels distinguish pulmonary arterial hypertension from left ventricular systolic dysfunction

Sandqvist, Anna; Schneede, Jörn; Kylhammar, David; Henrohn, D et al.

Part of Heart and Vessels, p. 255-263, 2018

• DOI for Plasma l-arginine levels distinguish pulmonary arterial hypertension from left ventricular systolic dysfunction
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Alterations in plasma L-arginine and methylarginines in heart failure and after heart transplantation

Lundgren, Jakob; Sandqvist, Anna; Hedeland, Mikael; Bondesson, Ulf et al.

Part of Scandinavian Cardiovascular Journal, p. 196-204, 2018

• DOI for Alterations in plasma L-arginine and methylarginines in heart failure and after heart transplantation

Dimethylarginines correlate to common carotid artery wall layer dimensions and cardiovascular risk factors in pregnant women with and without preeclampsia

Akhter, Tansim; Wikström, Gerhard; Larsson, Margareta; Bondesson, Ulf et al.

Part of Atherosclerosis, 2018

• DOI for Dimethylarginines correlate to common carotid artery wall layer dimensions and cardiovascular risk factors in pregnant women with and without preeclampsia

Cetirizine per os: exposure and antihistamine effect in the dog

Ekstrand, Carl; Ingvast-Larsson, Carina; Bondesson, Ulf; Hedeland, Mikael et al.

Part of Acta Veterinaria Scandinavica, 2018

• DOI for Cetirizine per os: exposure and antihistamine effect in the dog
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Equine in vivo-derived metabolites of the SARM LGD-4033 and comparison with human and fungal metabolites.

Hansson, Annelie; Knych, Heather; Stanley, Scott; Berndtson, Emma et al.

Part of Journal of chromatography. B, p. 91-98, 2018

• DOI for Equine in vivo-derived metabolites of the SARM LGD-4033 and comparison with human and fungal metabolites.

Reply to "Comment on 'In Vivo Drug Delivery Performance of Lipiodol-Based Emulsion or Drug-Eluting Beads in Patients with Hepatocellular Carcinoma'"

Dubbelboer, Ilse R; Lilienberg, Elsa; Karalli, Amar; Axelsson, Rimma et al.

Part of Molecular Pharmaceutics, p. 336-340, 2018

• DOI for Reply to "Comment on 'In Vivo Drug Delivery Performance of Lipiodol-Based Emulsion or Drug-Eluting Beads in Patients with Hepatocellular Carcinoma'"

Structural elucidation of major selective androgen receptor modulator (SARM) metabolites for doping control

Garg, Neeraj; Hansson, Annelie; Knych, Heather K.; Stanley, Scott D. et al.

Part of Organic and biomolecular chemistry, p. 698-702, 2018

• DOI for Structural elucidation of major selective androgen receptor modulator (SARM) metabolites for doping control

Investigation of the metabolites of the HIF stabilizer FG-4592 (roxadustat) in five different in vitro models and in a human doping control sample using high resolution mass spectrometry

Hansson, Annelie; Thevis, Mario; Cox, Holly; Miller, Geoff et al.

Part of Journal of Pharmaceutical and Biomedical Analysis, p. 228-236, 2017

• DOI for Investigation of the metabolites of the HIF stabilizer FG-4592 (roxadustat) in five different in vitro models and in a human doping control sample using high resolution mass spectrometry

Pharmacokinetics and pharmacodynamics of meldonium in exercised thoroughbred horses

Knych, Heather K.; Stanley, Scott D.; McKemie, Dan S.; Arthur, Rick M. et al.

Part of Drug Testing and Analysis, p. 1392-1399, 2017

• DOI for Pharmacokinetics and pharmacodynamics of meldonium in exercised thoroughbred horses

Quantification of dimethylsulfoxide (DMSO) in equine plasma and urine using HILIC-MS/MS

Salomonsson, Matilda L.; Bondesson, Ulf; Hedeland, Mikael

Part of Drug Testing and Analysis, p. 935-941, 2017

• DOI for Quantification of dimethylsulfoxide (DMSO) in equine plasma and urine using HILIC-MS/MS

Nickel in equine sports drug testing - pilot study results on urinary nickel concentrations

Thevis, M.; Machnik, M.; Schenk, I.; Krug, O. et al.

Part of Rapid Communications in Mass Spectrometry, p. 982-984, 2016

• DOI for Nickel in equine sports drug testing - pilot study results on urinary nickel concentrations

Investigation of the selective androgen receptor modulators S1, S4 and S22 and their metabolites in equine plasma using high-resolution mass spectrometry

Hansson, Annelie; Knych, Heather; Stanley, Scott; Thevis, Mario et al.

Part of Rapid Communications in Mass Spectrometry, p. 833-842, 2016

• DOI for Investigation of the selective androgen receptor modulators S1, S4 and S22 and their metabolites in equine plasma using high-resolution mass spectrometry

A quantitative approach to analysing cortisol response in the horse

Ekstrand, C.; Ingvast-Larsson, C.; Olsen, L.; Hedeland, Mikael et al.

Part of Journal of Veterinary Pharmacology and Therapeutics, p. 255-263, 2016

• DOI for A quantitative approach to analysing cortisol response in the horse

Seafood sold in Sweden contains BMAA: A study of free and total concentrations with UHPLC-MS/MS and dansyl chloride derivatization

Salomonsson, Matilda Lampinen; Fredriksson, Elisabeth; Alfjorden, Anders; Hedeland, Mikael et al.

Part of Toxicology reports, p. 1473-1481, 2015

• DOI for Seafood sold in Sweden contains BMAA: A study of free and total concentrations with UHPLC-MS/MS and dansyl chloride derivatization

Acute vasodilator response to vardenafil and clinical outcome in patients with pulmonary hypertension

Sandqvist, Anna; Henrohn, Dan; Egeröd, Hanna; Hedeland, Mikael et al.

Part of European Journal of Clinical Pharmacology, p. 1165-1173, 2015

• DOI for Acute vasodilator response to vardenafil and clinical outcome in patients with pulmonary hypertension

A novel trapping system for the detection of reactive drug metabolites using the fungus Cunninghamella elegans and high resolution mass spectrometry

Rydevik, Axel; Hansson, Annelie; Hellqvist, Anna; Bondesson, Ulf et al.

Part of Drug Testing and Analysis, p. 626-633, 2015

• DOI for A novel trapping system for the detection of reactive drug metabolites using the fungus Cunninghamella elegans and high resolution mass spectrometry

Characterization of equine urinary metabolites of selective androgen receptor modulators (SARMs) S1, S4 and S22 for doping control purposes

Hansson, Annelie; Knych, Heather; Stanley, Scott; Thevis, Mario et al.

Part of Drug Testing and Analysis, p. 673-683, 2015

• DOI for Characterization of equine urinary metabolites of selective androgen receptor modulators (SARMs) S1, S4 and S22 for doping control purposes

Plasma concentration-dependent suppression of endogenous hydrocortisone in the horse after intramuscular administration of dexamethasone-21-isonicotinate

Ekstrand, C.; Bondesson, Ulf; Gabrielsson, J.; Hedeland, Mikael et al.

Part of Journal of Veterinary Pharmacology and Therapeutics, p. 235-242, 2015

• DOI for Plasma concentration-dependent suppression of endogenous hydrocortisone in the horse after intramuscular administration of dexamethasone-21-isonicotinate

Characterization of a non-approved selective androgen receptor modulator drug candidate sold via the Internet and identification of in vitro generated phase-I metabolites for human sports drug testing

Thevis, Mario; Lagojda, Andreas; Kuehne, Dirk; Thomas, Andreas et al.

Part of Rapid Communications in Mass Spectrometry, p. 991-999, 2015

• DOI for Characterization of a non-approved selective androgen receptor modulator drug candidate sold via the Internet and identification of in vitro generated phase-I metabolites for human sports drug testing

Validation of the Endopep-MS method for qualitative detection of active botulinum neurotoxins in human and chicken serum

Bjornstad, Kristian; Åberg, Annica Tevell; Kalb, Suzanne R.; Wang, Dongxia et al.

Part of Analytical and Bioanalytical Chemistry, p. 7149-7161, 2014

• DOI for Validation of the Endopep-MS method for qualitative detection of active botulinum neurotoxins in human and chicken serum

High-resolution mass spectrometric investigation of the phase I and II metabolites of finasteride in pig plasma, urine and bile

Lundahl, Anna; Åberg, Annica Tevell; Bondesson, Ulf; Lennernäs, Hans et al.

Part of Xenobiotica, p. 498-510, 2014

• DOI for High-resolution mass spectrometric investigation of the phase I and II metabolites of finasteride in pig plasma, urine and bile

Effects of verapamil on the pharmacokinetics and hepatobiliary disposition of fexofenadine in pigs

Sjögren, Erik; Hedeland, Mikael; Bondesson, Ulf; Lennernäs, Hans

Part of European Journal of Pharmaceutical Sciences, p. 214-223, 2014

• DOI for Effects of verapamil on the pharmacokinetics and hepatobiliary disposition of fexofenadine in pigs

The Effects of Lipiodol and Cyclosporin A on the Hepatobiliary Disposition of Doxorubicin in Pigs

Dubbelboer, Ilse R; Lilienberg, Elsa; Hedeland, Mikael; Bondesson, Ulf et al.

Part of Molecular Pharmaceutics, p. 1301-1313, 2014

• DOI for The Effects of Lipiodol and Cyclosporin A on the Hepatobiliary Disposition of Doxorubicin in Pigs

Isolation and characterization of a beta-glucuronide of hydroxylated SARM S1 produced using a combination of biotransformation and chemical oxidation

Rydevik, Axel; Lagojda, Andreas; Thevis, Mario; Bondesson, Ulf et al.

Part of Journal of Pharmaceutical and Biomedical Analysis, p. 36-39, 2014

• DOI for Isolation and characterization of a beta-glucuronide of hydroxylated SARM S1 produced using a combination of biotransformation and chemical oxidation

Investigation of Hepatobiliary Disposition of Doxorubicin Following Intrahepatic Delivery of Different Dosage Forms

Lilienberg, Elsa; Ebeling-Barbier, Charlotte; Nyman, Rickard; Hedeland, Mikael et al.

Part of Molecular Pharmaceutics, p. 131-144, 2014

• DOI for Investigation of Hepatobiliary Disposition of Doxorubicin Following Intrahepatic Delivery of Different Dosage Forms

The fungus Cunninghamella elegans can produce human and equine metabolites of selective androgen receptor modulators (SARMs)

Rydevik, Axel; Thevis, Mario; Krug, Oliver; Bondesson, Ulf et al.

Part of Xenobiotica, p. 409-420, 2013

• DOI for The fungus Cunninghamella elegans can produce human and equine metabolites of selective androgen receptor modulators (SARMs)

Synthesis, characterization, and detection of new oxandrolone metabolites as long-term markers in sports drug testing

Guddat, S.; Fusshoeller, G.; Beuck, S.; Thomas, A. et al.

Part of Analytical and Bioanalytical Chemistry, p. 8285-8294, 2013

• DOI for Synthesis, characterization, and detection of new oxandrolone metabolites as long-term markers in sports drug testing

Intramuscular administration of sodium benzylpenicillin in horses as an alternative to procaine benzylpenicillin

Olsen, Lena; Bremer, Hanna; Olofsson, Karin; Brojer, Johan et al.

Part of Research in Veterinary Science, p. 212-218, 2013

• DOI for Intramuscular administration of sodium benzylpenicillin in horses as an alternative to procaine benzylpenicillin

Methadone in healthy goats: Pharmacokinetics, behaviour and blood pressure

Olsen, L.; Olsson, K.; Hydbring-Sandberg, E.; Bondesson, Ulf et al.

Part of Research in Veterinary Science, p. 231-237, 2013

• DOI for Methadone in healthy goats: Pharmacokinetics, behaviour and blood pressure

High inter-individual variability of vardenafil pharmacokinetics in patients with pulmonary hypertension

Sandqvist, A. M.; Henrohn, Dan; Schneede, J.; Hedeland, Mikael et al.

Part of European Journal of Clinical Pharmacology, p. 197-207, 2013

• DOI for High inter-individual variability of vardenafil pharmacokinetics in patients with pulmonary hypertension

Mass spectrometric characterization of glucuronides formed by a new concept, combining Cunninghamella elegans with TEMPO

Rydevik, Axel; Bondesson, Ulf; Thevis, Mario; Hedeland, Mikael

Part of Journal of Pharmaceutical and Biomedical Analysis, p. 278-284, 2013

• DOI for Mass spectrometric characterization of glucuronides formed by a new concept, combining Cunninghamella elegans with TEMPO

Development and in-house validation of a method for quantification of BMAA in mussels using dansyl chloride derivatization and ultra performance liquid chromatography tandem mass spectrometry

Salomonsson, Matilda Lampinen; Hansson, Annelie; Bondesson, Ulf

Part of Analytical Methods, p. 4865-4874, 2013

• DOI for Development and in-house validation of a method for quantification of BMAA in mussels using dansyl chloride derivatization and ultra performance liquid chromatography tandem mass spectrometry

Development and in-house validation of an LC-MS/MS method for the quantification of the mycotoxins deoxynivalenol, zearalenone, T-2 and HT-2 toxin, ochratoxin A and fumonisin B1 and B2 in vegetable animal feed

Tevell Åberg, Annica; Solyakov, Alexey; Bondesson, Ulf

Part of Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, p. 541-549, 2013

• DOI for Development and in-house validation of an LC-MS/MS method for the quantification of the mycotoxins deoxynivalenol, zearalenone, T-2 and HT-2 toxin, ochratoxin A and fumonisin B1 and B2 in vegetable animal feed

Acute haemodynamic response in relation to plasma vardenafil concentrations in patients with pulmonary hypertension

Henrohn, Dan; Sandqvist, Anna; Hedeland, Mikael; Egeröd, Hanna et al.

Part of British Journal of Clinical Pharmacology, p. 990-998, 2012

• DOI for Acute haemodynamic response in relation to plasma vardenafil concentrations in patients with pulmonary hypertension

Structural elucidation of phase I and II metabolites of bupivacaine in horse urine and fungi of the Cunninghamella species using liquid chromatography/multi-stage mass spectrometry

Rydevik, Axel; Bondesson, Ulf; Mikael, Hedeland

Part of Rapid Communications in Mass Spectrometry, p. 1338-1346, 2012

• DOI for Structural elucidation of phase I and II metabolites of bupivacaine in horse urine and fungi of the Cunninghamella species using liquid chromatography/multi-stage mass spectrometry

Characterization of In Vitro Synthesized Equine Metabolites of the Selective Androgen Receptor Modulators S24 and S4

Krug, Oliver; Thomas, Andreas; Beuck, Simon; Schenk, Ina et al.

Part of Journal of Equine Veterinary Science, p. 562-568, 2012

• DOI for Characterization of In Vitro Synthesized Equine Metabolites of the Selective Androgen Receptor Modulators S24 and S4

Detection of recombinant human EPO administered to horses using MAIIA lateral flow isoform test

Lönnberg, Maria; Bondesson, Ulf; Cormant, Florence; Garcia, Patrice et al.

Part of Analytical and Bioanalytical Chemistry, p. 1619-1628, 2012

• DOI for Detection of recombinant human EPO administered to horses using MAIIA lateral flow isoform test

Pharmacokinetics and effects of cetirizine in horses with insect bite hypersensitivity

Olsén, Lena; Bondesson, Ulf; Broström, Hans; Olsson, Ulf et al.

Part of The Veterinary Journal, p. 347-351, 2011

• DOI for Pharmacokinetics and effects of cetirizine in horses with insect bite hypersensitivity

Confirmation of botulism in birds and cattle by the mouse bioassay and Endopep-MS

Hedeland, Mikael; Moura, Hercules; Båverud, Viveca; Woolfitt, Adrian R et al.

Part of Journal of Medical Microbiology, p. 1299-1305, 2011

• DOI for Confirmation of botulism in birds and cattle by the mouse bioassay and Endopep-MS

Pharmacokinetics of meloxicam in adult goats and its analgesic effect in disbudded kids

Ingvast-Larsson, C.; Högberg, M.; Mengistu, U.; Olsén, L. et al.

Part of Journal of Veterinary Pharmacology and Therapeutics, p. 64-69, 2011

• DOI for Pharmacokinetics of meloxicam in adult goats and its analgesic effect in disbudded kids

In Vivo Investigation in Pigs of Intestinal Absorption, Hepatobiliary Disposition, and Metabolism of the 5 alpha-Reductase Inhibitor Finasteride and the Effects of Coadministered Ketoconazole

Lundahl, Anna; Hedeland, Mikael; Bondesson, Ulf; Lennernäs, Hans

Part of Drug Metabolism And Disposition, p. 847-857, 2011

• DOI for In Vivo Investigation in Pigs of Intestinal Absorption, Hepatobiliary Disposition, and Metabolism of the 5 alpha-Reductase Inhibitor Finasteride and the Effects of Coadministered Ketoconazole

Effect of a Single Gemfibrozil Dose on the Pharmacokinetics of Rosuvastatin in Bile and Plasma in Healthy Volunteers

Bergman, Ebba; Matsson, Elin M; Hedeland, Mikael; Bondesson, Ulf et al.

Part of Journal of clinical pharmacology, p. 1039-1049, 2010

• DOI for Effect of a Single Gemfibrozil Dose on the Pharmacokinetics of Rosuvastatin in Bile and Plasma in Healthy Volunteers

The Effect of Acute Administration of Rifampicin and Imatinib on the Enterohepatic Transport of Rosuvastatin In Vivo

Bergman, Ebba; Hedeland, Mikael; Bondesson, Ulf; Lennernäs, Hans

Part of Xenobiotica, p. 558-568, 2010

• DOI for The Effect of Acute Administration of Rifampicin and Imatinib on the Enterohepatic Transport of Rosuvastatin In Vivo

Structural elucidation of N-oxidized clemastine metabolites by liquid chromatography/tandem mass spectrometry and the use of Cunninghamella elegans to facilitate drug metabolite identification

Tevell Åberg, Annica; Löfgren, Helena; Bondesson, Ulf; Hedeland, Mikael

Part of Rapid Communications in Mass Spectrometry, p. 1447-1456, 2010

• DOI for Structural elucidation of N-oxidized clemastine metabolites by liquid chromatography/tandem mass spectrometry and the use of Cunninghamella elegans to facilitate drug metabolite identification

Clinical pharmacology of methadone in dogs

Ingvast-Larsson, Carina; Holgersson, Anja; Bondesson, Ulf; Lagerstedt, Anne-Sofie et al.

Part of Veterinary Anaesthesia and Analgesia, p. 48-56, 2010

• DOI for Clinical pharmacology of methadone in dogs

The Enterohepatic Disposition of Rosuvastatin in Pigs and The Impact of Concomitant Dosing with Cyclosporine and Gemfibrozil

Bergman, Ebba; Lundahl, Anna; Fridblom, Patrik; Hedeland, Mikael et al.

Part of Drug Metabolism And Disposition, p. 2349-2358, 2009

• DOI for The Enterohepatic Disposition of Rosuvastatin in Pigs and The Impact of Concomitant Dosing with Cyclosporine and Gemfibrozil

Different effects of ketoconazole on the stereoselective first-pass metabolism of R/S-verapamil in the intestine and the liver: important for the mechanistic understanding of first-pass drug-drug interactions

Thörn, Helena Anna; Hedeland, Mikael; Bondesson, Ulf; Knutson, Lars et al.

Part of Drug Metabolism And Disposition, p. 2186-2196, 2009

• DOI for Different effects of ketoconazole on the stereoselective first-pass metabolism of R/S-verapamil in the intestine and the liver: important for the mechanistic understanding of first-pass drug-drug interactions

Identification of Finasteride Metabolites in Human Bile and Urine by High-Performance Liquid Chromatography/Tandem Mass Spectrometry

Lundahl, Anna; Lennernäs, Hans; Knutson, Lars; Bondesson, Ulf et al.

Part of Drug Metabolism And Disposition, p. 2008-2017, 2009

• DOI for Identification of Finasteride Metabolites in Human Bile and Urine by High-Performance Liquid Chromatography/Tandem Mass Spectrometry

In vitro formation of phase I and II metabolites of propranolol and determination of their structures using chemical derivatization and liquid chromatography tandem mass spectrometry

Lampinen Salomonsson, Matilda; Bondesson, Ulf; Hedeland, Mikael

Part of Journal of Mass Spectrometry, p. 742-754, 2009

• DOI for In vitro formation of phase I and II metabolites of propranolol and determination of their structures using chemical derivatization and liquid chromatography tandem mass spectrometry

A mass spectromeric study on meloxicam metabolism in horses and the fungus Cunninghamella elegans, and the relevance of this microbial system as a model of drug metabolism in the horse

Tevell Åberg, Annica; Olsson, Charlotte; Bondesson, Ulf; Hedeland, Mikael

Part of Journal of Mass Spectrometry, p. 1026-1037, 2009

• DOI for A mass spectromeric study on meloxicam metabolism in horses and the fungus Cunninghamella elegans, and the relevance of this microbial system as a model of drug metabolism in the horse

The effect of St. John's wort on the pharmacokinetics, metabolism and biliary excretion of finasteride and its metabolites in healthy men

Lundahl, Anna; Hedeland, Mikael; Bondesson, Ulf; Knutson, Lars et al.

Part of European Journal of Pharmaceutical Sciences, p. 433-443, 2009

• DOI for The effect of St. John's wort on the pharmacokinetics, metabolism and biliary excretion of finasteride and its metabolites in healthy men

Cetirizine in horses: Pharmacokinetics and pharmacodynamics following repeated oral administration

Olsén, Lena; Bondesson, Ulf; Broström, Hans; Tjälve, Hans et al.

Part of The Veterinary Journal, p. 242-249, 2008

• DOI for Cetirizine in horses: Pharmacokinetics and pharmacodynamics following repeated oral administration

Structural evaluation of the glucuronides of morphine and formoterol using chemical derivatization with 1,2-dimethylimidazole-4-sulfonyl chloride and liquid chromatography/ion trap mass spectrometry

Lampinen Salomonsson, Matilda; Bondesson, Ulf; Hedeland, Mikael

Part of Rapid Communications in Mass Spectrometry, p. 2685-2697, 2008

• DOI for Structural evaluation of the glucuronides of morphine and formoterol using chemical derivatization with 1,2-dimethylimidazole-4-sulfonyl chloride and liquid chromatography/ion trap mass spectrometry

Cetirizine in horses: pharmacokinetics and effect of ivermectin pretreatment

Olsén, L.; Ingvast-Larsson, C.; Bondesson, Ulf; Broström, H. et al.

Part of Journal of Veterinary Pharmacology and Therapeutics, p. 194-200, 2007

• DOI for Cetirizine in horses: pharmacokinetics and effect of ivermectin pretreatment

Clinical pharmacology of buprenorphine in healthy, lactating goats

Ingvast-Larsson, C.; Svartberg, K.; Hydbring-Sandberg, E.; Bondesson, Ulf et al.

Part of Journal of Veterinary Pharmacology and Therapeutics, p. 249-256, 2007

• DOI for Clinical pharmacology of buprenorphine in healthy, lactating goats

Biliary secretion of rosuvastatin and bile acids in humans during the absorption phase.

Bergman, Ebba; Forsell, Patrik; Tevell, Annica; Persson, Eva M et al.

Part of Eur J Pharm Sci, p. 205-14, 2006

First-pass effects of verapamil on the intestinal absorption and liver disposition of fexofenadine in the porcine model.

Petri, Niclas; Bergman, Ebba; Forsell, Patrik; Hedeland, Mikael et al.

Part of Drug Metab Dispos, p. 1182-9, 2006

Effect of erythromycin on the absorption of fexofenadine in the jejunum, ileum and colon determined using local intubation in healthy volunteers.

Petri, N; Borga, O; Nyberg, L; Hedeland, M et al.

Part of Int J Clin Pharmacol Ther, p. 71-9, 2006

Detection of altrenogest and its metabolites in post administration horse urine using liquid chromatography tandem mass spectrometry-increased sensitivity by chemical derivatisation of the glucuronic acid conjugate.

Lampinen-Salomonsson, Matilda; Beckman, Elin; Bondesson, Ulf; Hedeland, Mikael

Part of J Chromatogr B Analyt Technol Biomed Life Sci, p. 245-56, 2006

Fexofenadine in horses: pharmacokinetics, pharmacodynamics and effect of ivermectin pretreatment.

Olsén, L; Ingvast-Larsson, C; Larsson, P; Broström, H et al.

Part of J Vet Pharmacol Ther, p. 129-35, 2006

Differentiation of estriol glucuronide isomers by chemical derivatization and electrospray tandem mass spectrometry

Lampinen-Salomonsson, Matilda; Bondesson, Ulf; Petersson, Carl; Hedeland, Mikael

Part of Rapid Commun Mass Spectrom, p. 1429-40, 2006

Flutamide metabolism in four different species in vitro and identification of flutamide metabolites in human patient urine by high performance liquid chromatography/tandem mass spectrometry.

Tevell, Annica; Lennernäs, Hans; Jönsson, Mats; Norlin, Maria et al.

Part of Drug Metab Dispos, p. 984-92, 2006

St John's wort decreases the bioavailability of R- and S-verapamil through induction of the first-pass metabolism

Tannergren, Christer; Engman, Helena; Knutson, Lars; Hedeland, Mikael et al.

Part of Clinical Pharmacology and Therapeutics, p. 298-309, 2004

• DOI for St John's wort decreases the bioavailability of R- and S-verapamil through induction of the first-pass metabolism

Simultaneous quantification of the enantiomers of verapamil and its N-demethylated metabolite in human plasma using liquid chromatography-tandem mass spectrometry

Hedeland, Mikael; Fredriksson, Elisabeth; Lennernäs, Hans; Bondesson, Ulf

Part of Journal of chromatography. B, p. 303-311, 2004

• DOI for Simultaneous quantification of the enantiomers of verapamil and its N-demethylated metabolite in human plasma using liquid chromatography-tandem mass spectrometry

Identification of some new clemastine metabolites in dog, horse, and human urine with liquid chromatography/tandem mass spectrometry.

Tevell, Annica; Bondesson, Ulf; Törneke, Karolina; Hedeland, Mikael

Part of Rapid Commun Mass Spectrom, p. 2267-72, 2004

Clinical pharmacology of clemastine in healthy dogs.

Hansson, H; Bergvall, K; Bondesson, U; Hedeland, M et al.

Part of Vet Dermatol, p. 152-8, 2004

Development of a chiral non-aqueous capillary electrophoretic system using the partial filling technique with UV and mass spectrometric detection

Lodén, Henrik; Hedeland, Ylva; Hedeland, Mikael; Bondesson, Ulf et al.

Part of Journal of Chromatography A, p. 143-152, 2003

• DOI for Development of a chiral non-aqueous capillary electrophoretic system using the partial filling technique with UV and mass spectrometric detection

Chiral separation of amines with N-benzoxycarbonylglycyl-L-proline as selector in non-aqueous capillary electrophoresis using methanol and 1,2-dichloroethane in the background electrolyte

Hedeland, Ylva; Hedeland, Mikael; Bondesson, Ulf; Pettersson, Curt

Part of Journal of Chromatography A, p. 261-271, 2003

• DOI for Chiral separation of amines with N-benzoxycarbonylglycyl-L-proline as selector in non-aqueous capillary electrophoresis using methanol and 1,2-dichloroethane in the background electrolyte

Multiple transport mechanisms involved in the intestinal absorption and first-pass extraction of fexofenadine.

Tannergren, Christer; Petri, Niclas; Knutson, Lars; Hedeland, Mikael et al.

Part of Clin Pharmacol Ther, p. 423-36, 2003

Non-aquoeus capillary electrophoretic separation of enantiomeric amines with (-)-2,3:4,6-di-O-isopropylidene-2-keto-L-gulonic acid as chiral counter ion

Carlsson, Ylva; Hedeland, Mikael; Bondesson, Ulf; Pettersson, Curt

Part of Journal of Chromatography A, p. 303-311, 2001

• DOI for Non-aquoeus capillary electrophoretic separation of enantiomeric amines with (-)-2,3:4,6-di-O-isopropylidene-2-keto-L-gulonic acid as chiral counter ion

Non-aqueous capillary electrophoretic separation of enantiomeric amineswith (-)-2,3:4,6-di-O-isopropylidene-2-keto-L-gulonic acid as chiralcounter ion.

Carlsson, Y; Hedeland, M; Bondesson, U; Pettersson, C

Part of J Chromatogr A, p. 303, 2001

Characterization of a Selective Androgen Receptor Modulator Drug Candidate and Identification of In Vitro Generated Metabolites for Sports Drug Testing

Hansson, Annelie; Thevis, Mario; Lagodja, Andreas; Thomas, Andreas et al.

2015

Antihistamine effect of cetirizine after oral administrator in the dog

Ekstrand, Carl; Ingvast-Larsson, Carina; Bondesson, Ulf; Hedeland, Mikael et al.

2015

A quantitative approach to analysing hydrocortisone response in the horse

Ekstrand, Carl; Ingvast-Larsson, Carina; Olsén, Lena; Hedeland, Mikael et al.

2015

Quantification of SARMs S1, S4 and S22 and detection of their metabolites in equine plasma usning UHPLC-Q-TOF

Hansson, Annelie; Knych, Heather; Stanley, Scott; Thevis, Mario et al.

2015

Quantification of SARMs S1, S4 and S22 and detection of their metabolites in equine plasma using UHPLC-Q-TOF

Hansson, Annelie; Knych, Heather; Stanley, Scott; Thevis, Mario et al.

2015

Charactierization of a selective androgen receptor modulator drug candidate and identification of in vitro generated metabolites for sports drug testing

Thevis, Mario; Lagojda, Andreas; Thomas, Andreas; Dib, Josef et al.

2015

Validation of the endopep-MS method for qualitative detection of active botulinum neurotoxins in human or chicken serum

Björnstad, Kristian; Tevell Åberg, Annica; Kalb, Suzanne; Wang, Dongxia et al.

2014

Additional evidence for dexamethasone screening limits

Ekstrand, Carl; Bondesson, Ulf; Falkenö, Ulrika; Gabrielsson, Johan et al.

2014

In vivo metabolism of Selective Androgen Receptor Modulators (SARMs) in the horse

Hedeland, Mikael; Hansson, Annelie; Rydevik, Axel; Krug, Oliver et al.

2014

In vivo metabolism of selective androgen receptor modulators (SARMs) in the horse

Hedeland, Mikael; Hansson, Annelie; Rydevik, Axel; Krug, Oliver et al.

2014

Turning drug glucosides into glucuronides - making fungal incubations work together with chemical derivatization

Rydevik, Axel; Bondesson, Ulf; Thevis, Mario; Hedeland, Mikael

2013

Evaluation of the fungus Cunninghamella elegans as a model for the formation of reactive metabolites using glutathione trapping and UHPLCC/HRMS

Rydevik, Axel; Hellqvist, Anna; Bondesson, Ulf; Hedeland, Mikael

2013

Drug glucuronides synthesized using a new concept combining Cunninghamella elegans with TEMPO

Rydevik, Axel; Bondesson, Ulf; Thevis, Mario; Hedeland, Mikael

2013

Mass spectrometric study of the metabolism of Selective Androgen Receptor Modulators (SARMs) in the fungus Cunninghamella elegans

Hedeland, Mikael; Rydevik, Axel; Krug, O; Thevis, M et al.

2012

A mass spectrometric study of bupivacaine metabolites found in fungi and horse

Rydevik, Axel; Hedeland, Mikael; Bondesson, Ulf

2012

Verapamil Affects the Pharmacokinetics and the Hepatic Disposition of Fexofenadine in Pigs

Sjögren, E; Hedeland, Mikael; Bondesson, Ulf; Lennernäs, H

2012

A mass spectrometric study of bupivacaine metabolites found in fungi and horse

Rydevik, Axel; Bondesson, Ulf; Hedeland, Mikael

2012

Mass spectrometric study of the metabolism of Selective Androgen Receptor Modulators (SARMs) in the fungus Cunninghamella elegans

Hedeland, Mikael; Rydevik, Axel; Krug, O; Thevis, M et al.

2012

Comparison of vardenafil and adenosine for vasoreactivity testing in patients with pulmonary hypertension

Sandqvist, A; Henrohn, D; Schneede, J; Egerod, H et al.

2012

Local and sustained release in the treatment of primary liver cancer? Pharmacokinetic understanding of two formulations for intra arterial injection

Lilienberg, E; Ebeling Barbier, C; Nyman, C; Hedeland, Mikael et al.

2012

Improved Pharmacokinetic Understanding of Two Formulations for Intra-arterial Injection

Lilienberg, E; Ebeling Barbier, C; Nyman, R; Hedeland, Mikael et al.

2012

Mass spectrometric study of the metabolism of Selective Androgen Receptor Modulators (SARMs) in the fungus Cunninghamella elegans

Hedeland, Mikael; Rydevik, Axel; Krug, O; Thevis, M et al.

2012

Improved Pharmacokinetic Understanding of Two Formulations for Intra-arterial Injection

Lilienberg, E; Ebeling Barbier, C; Nyman, R; Hedeland, Mikael et al.

2012

The relevance of using a fungus as a model of equine metabolism

Hedeland, Mikael; Tevell Åberg, Annica; Bondesson, Ulf

2010

Metabolite identification by mass spectrometry of the 5α-reductase inhibitor finasteride in vitro and in vivo

Lundahl, A; Tevell Åberg, Annica; Bondesson, Ulf; Hedeland, Mikael et al.

2009

The effect of gemfibrozil on the biliary excretion of rosuvastatin in pig and man

Bergman, E; Lundahl, A; Forsell, P; Hedeland, Mikael et al.

2009

Identification of hydroxylated and glucuronidated metabolites of finasteride in human bile and urine

Lundahl, A; Lennernäs, H; Knutson, L; Bondesson, Ulf et al.

2009

Different effects of ketoconazole on the stereoselective first-pass metabolism of R/S-verapamil in the intestine and the liver

Thörn, H; Hedeland, Mikael; Bondesson, Ulf; Knutson, L et al.

2009

Metabolitidentifiering av finasterid i human galla och urin

Lundahl, A; Hedeland, Mikael; Bondesson, Ulf; Knutson, L et al.

2009

The hepatobiliary disposition of rosuvastatin in pigs and the impact of concomitant dosing with cyclosporine.

Bergman, E; Lundahl, A; Forsell, P; Hedeland, Mikael et al.

2009

Characterization of C- and N-oxidized Clemastine Metabolites using LC-MSⁿ

Tevell Åberg, Annica; Bondesson, Ulf; Hedeland, Mikael

2008

Structural evaluation of glucuronides of morphine and formoterol using chemical derivatization with 1,2-dimethylimidazole-4-sulfonyl chloride and LC-MSⁿ

Salomonsson, Matilda; Bondesson, Ulf; Hedeland, Mikael

2008

Intestinal and liver CYP3A4-mediated metabolism of R/S-verapamil in pigs

Eriksson, H; Hedeland, Mikael; Bondesson, Ulf; Knutson, L et al.

2008

The effect of St John's Wort on the pharmacokinetics and metabolism of finasteride in healthy men

Lundahl, A; Hedeland, Mikael; Bondesson, Ulf; Knutsson, L et al.

2008

The effect of St John’s wort on the pharmacokinetics and metabolism of finasteride in man

Lundahl, A; Hedeland, Mikael; Bondesson, Ulf; Knutson, L et al.

2008

The effect of St. John’s wort treatment on finasteride pharmacokinetics and identification of new phase I and phase II metabolites in humans

Lundahl, A; Hedeland, Mikael; Bondesson, Ulf; Knutson, L et al.

2008

The biliary excretion of rosuvastatin and gemfibrozil in healthy humans

Bergman, E; Sjödin, E; Forsell, P; Hedeland, Mikael et al.

2008

The effect of St John’s Wort treatment on finasteride metabolism and identification of new finasteride metabolites in humans

Lundahl, A; Hedeland, Mikael; Bondesson, Ulf; Knutson, L et al.

2008

The biliary excretion of rosuvastatin and gemfibrozil in healthy humans

Bergman, E; Sjödin, E; Forsell, P; Hedeland, Mikael et al.

2008

Optimization of In Vitro Microsome Incubations for Improved Drug Metabolite Yield Utilizing Experimental Design

Nilsson Broberg, Malin; Haglöf, Jakob; Bondesson, Ulf; Pettersson, Curt et al.