Fredrik Rosqvist
Associated Researcher at Department of Public Health and Caring Sciences; Clinical Nutrition and Metabolism
- Visiting address:
- Husargatan 3, BMC
751 22 Uppsala - Postal address:
- Husargatan 3, BMC, Box 564
751 22 UPPSALA
Researcher at Department of Public Health and Caring Sciences; Clinical Nutrition and Metabolism
- E-mail:
- fredrik.rosqvist@uu.se
- Visiting address:
- Husargatan 3, BMC
751 22 Uppsala - Postal address:
- Husargatan 3, BMC, Box 564
751 22 UPPSALA
Senior Lecturer/Associate Professor at Department of food studies, nutrition and dietetics
- E-mail:
- fredrik.rosqvist@ikv.uu.se
- Visiting address:
- BMC
Husargatan 3
752 37 Uppsala - Postal address:
- Box 560
751 22 UPPSALA
Short presentation
My research is focusing on the relation between the type of fat in the diet and cardiometabolic health. I work with both intervention studies and epidemiological studies. Background as a molecular nutritionist, with a keen interest in aspects of fatty acid metabolism and related areas.

Publications
Recent publications
Astrocytic lipid droplets contain MHCII and may act as cogs in the antigen presentation machinery
Part of Journal of Neuroinflammation, 2025
- DOI for Astrocytic lipid droplets contain MHCII and may act as cogs in the antigen presentation machinery
- Download full text (pdf) of Astrocytic lipid droplets contain MHCII and may act as cogs in the antigen presentation machinery
Part of Nature Medicine, p. 2867-2877, 2024
- DOI for Lipidome changes due to improved dietary fat quality inform cardiometabolic risk reduction and precision nutrition
- Download full text (pdf) of Lipidome changes due to improved dietary fat quality inform cardiometabolic risk reduction and precision nutrition
Part of American Journal of Clinical Nutrition, p. 187-195, 2024
- DOI for Substitutions of saturated fat intakes with other macronutrients and foods and risk of NAFLD cirrhosis and all-cause hepatocellular carcinoma: a prospective cohort study
- Download full text (pdf) of Substitutions of saturated fat intakes with other macronutrients and foods and risk of NAFLD cirrhosis and all-cause hepatocellular carcinoma: a prospective cohort study
Part of Metabolism, 2024
Part of Metabolism, 2024
All publications
Articles in journal
Astrocytic lipid droplets contain MHCII and may act as cogs in the antigen presentation machinery
Part of Journal of Neuroinflammation, 2025
- DOI for Astrocytic lipid droplets contain MHCII and may act as cogs in the antigen presentation machinery
- Download full text (pdf) of Astrocytic lipid droplets contain MHCII and may act as cogs in the antigen presentation machinery
Part of Nature Medicine, p. 2867-2877, 2024
- DOI for Lipidome changes due to improved dietary fat quality inform cardiometabolic risk reduction and precision nutrition
- Download full text (pdf) of Lipidome changes due to improved dietary fat quality inform cardiometabolic risk reduction and precision nutrition
Part of American Journal of Clinical Nutrition, p. 187-195, 2024
- DOI for Substitutions of saturated fat intakes with other macronutrients and foods and risk of NAFLD cirrhosis and all-cause hepatocellular carcinoma: a prospective cohort study
- Download full text (pdf) of Substitutions of saturated fat intakes with other macronutrients and foods and risk of NAFLD cirrhosis and all-cause hepatocellular carcinoma: a prospective cohort study
Part of Metabolism, 2024
Part of Metabolism, 2024
Part of American Journal of Clinical Nutrition, p. 985-986, 2024
Part of American Journal of Clinical Nutrition, p. 187-195, 2024
- DOI for Substitutions of saturated fat intakes with other macronutrients and foods and risk of NAFLD cirrhosis and all-cause hepatocellular carcinoma: a prospective cohort study
- Download full text (pdf) of Substitutions of saturated fat intakes with other macronutrients and foods and risk of NAFLD cirrhosis and all-cause hepatocellular carcinoma: a prospective cohort study
Part of Clinical Nutrition, p. 915-925, 2024
Fats and oils – a scoping review for Nordic Nutrition Recommendations 2023
Part of Food & Nutrition Research, 2024
Part of American Journal of Clinical Nutrition, p. 121-128, 2024
- DOI for Overfeeding polyunsaturated fat compared to saturated fat does not differentially influence lean tissue accumulation in overweight individuals: a randomized controlled trial
- Download full text (pdf) of Overfeeding polyunsaturated fat compared to saturated fat does not differentially influence lean tissue accumulation in overweight individuals: a randomized controlled trial
Part of European Journal of Nutrition, p. 145-153, 2023
- DOI for Substitution analyses of foods with varying fat quality and the associations with all-cause mortality and impact of the FADS-1 genotype in elderly men
- Download full text (pdf) of Substitution analyses of foods with varying fat quality and the associations with all-cause mortality and impact of the FADS-1 genotype in elderly men
Part of Cell Metabolism, p. 1887-189600000, 2023
- DOI for The PNPLA3 I148M variant increases ketogenesis and decreases hepatic de novo lipogenesis and mitochondrial function in humans
- Download full text (pdf) of The PNPLA3 I148M variant increases ketogenesis and decreases hepatic de novo lipogenesis and mitochondrial function in humans
Part of Clinical Nutrition, p. 1922-1931, 2023
- DOI for Diet composition, nutrient substitutions and circulating fatty acids in relation to ectopic and visceral fat depots
- Download full text (pdf) of Diet composition, nutrient substitutions and circulating fatty acids in relation to ectopic and visceral fat depots
Part of Journal of Nutrition, p. 683-690, 2023
- DOI for Contrasting Carbohydrate Quantity and Quality and the Effects on Plasma Saturated and Monounsaturated Fatty Acids in Healthy Adults: A Randomized Controlled Trial
- Download full text (pdf) of Contrasting Carbohydrate Quantity and Quality and the Effects on Plasma Saturated and Monounsaturated Fatty Acids in Healthy Adults: A Randomized Controlled Trial
Part of Clinical Nutrition, p. 805-809, 2022
- DOI for Fatty acids in multiple circulating lipid fractions reflects the composition of liver triglycerides in humans
- Download full text (pdf) of Fatty acids in multiple circulating lipid fractions reflects the composition of liver triglycerides in humans
Part of Frontiers in Medicine, 2022
- DOI for Hepatic Unsaturated Fatty Acids Are Linked to Lower Degree of Fibrosis in Non-alcoholic Fatty Liver Disease
- Download full text (pdf) of Hepatic Unsaturated Fatty Acids Are Linked to Lower Degree of Fibrosis in Non-alcoholic Fatty Liver Disease
Part of Frontiers in Nutrition, 2022
- DOI for Effects of sugar-sweetened soda on plasma saturated and monounsaturated fatty acids in individuals with obesity: A randomized study
- Download full text (pdf) of Effects of sugar-sweetened soda on plasma saturated and monounsaturated fatty acids in individuals with obesity: A randomized study
Part of Frontiers in Nutrition, 2022
- DOI for Association of Daily Eating Duration and Day-To-Day Variability in the Timing of Eating With Fatal Cancer Risk in Older Men
- Download full text (pdf) of Association of Daily Eating Duration and Day-To-Day Variability in the Timing of Eating With Fatal Cancer Risk in Older Men
Part of Frontiers in nutrition, 2022
- DOI for Intake of Ultra-Processed Food and Ectopic-, Visceral- and Other Fat Depots: A Cross-Sectional Study.
- Download full text (pdf) of Intake of Ultra-Processed Food and Ectopic-, Visceral- and Other Fat Depots: A Cross-Sectional Study.
Part of Clinical Nutrition, p. 2637-2643, 2022
- DOI for Circulating fatty acids from high-throughput metabolomics platforms as potential biomarkers of dietary fatty acids
- Download full text (pdf) of Circulating fatty acids from high-throughput metabolomics platforms as potential biomarkers of dietary fatty acids
Part of Clinical Nutrition, p. 441-451, 2022
- DOI for Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids
- Download full text (pdf) of Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids
Editorial: Foods and Macronutrients in NAFLD: Associations, Effects and Mechanisms
Part of Frontiers in Nutrition, 2021
- DOI for Editorial: Foods and Macronutrients in NAFLD: Associations, Effects and Mechanisms
- Download full text (pdf) of Editorial: Foods and Macronutrients in NAFLD: Associations, Effects and Mechanisms
Part of Upsala Journal of Medical Sciences, 2021
- DOI for The influence of nutritional state on the fatty acid composition of circulating lipid fractions: implications for their use as biomarkers of dietary fat intake
- Download full text (pdf) of The influence of nutritional state on the fatty acid composition of circulating lipid fractions: implications for their use as biomarkers of dietary fat intake
Oxidation of dietary linoleate occurs to a greater extent than dietary palmitate in vivo in humans
Part of Clinical Nutrition, p. 1108-1114, 2021
Part of American Journal of Clinical Nutrition, p. 1743-1751, 2021
- DOI for Associations between fatty acid composition in serum cholesteryl esters and liver fat, basal fat oxidation, and resting energy expenditure: a population-based study
- Download full text (pdf) of Associations between fatty acid composition in serum cholesteryl esters and liver fat, basal fat oxidation, and resting energy expenditure: a population-based study
Part of Diabetes Care, p. 1134-1141, 2020
Part of Frontiers in Nutrition, 2020
- DOI for Abdominal Fat and Metabolic Health Markers but Not PNPLA3 Genotype Predicts Liver Fat Accumulation in Response to Excess Intake of Energy and Saturated Fat in Healthy Individuals
- Download full text (pdf) of Abdominal Fat and Metabolic Health Markers but Not PNPLA3 Genotype Predicts Liver Fat Accumulation in Response to Excess Intake of Energy and Saturated Fat in Healthy Individuals
The influence of dietary fatty acids on liver fat content and metabolism
Part of Proceedings of the Nutrition Society, p. 30-41, 2020
Part of Upsala Journal of Medical Sciences, p. 211-216, 2020
- DOI for Using total plasma triacylglycerol to assess hepatic de novo lipogenesis as an alternative to VLDL triacylglycerol
- Download full text (pdf) of Using total plasma triacylglycerol to assess hepatic de novo lipogenesis as an alternative to VLDL triacylglycerol
Part of Nutrition & Diabetes, 2019
- DOI for Energy restriction in obese women suggest linear reduction of hepatic fat content and time-dependent metabolic improvements
- Download full text (pdf) of Energy restriction in obese women suggest linear reduction of hepatic fat content and time-dependent metabolic improvements
Part of Journal of Clinical Endocrinology and Metabolism, p. 6207-6219, 2019
- DOI for Overeating saturated fat promotes fatty liver and ceramides compared to polyunsaturated fat: a randomized trial
- Download full text (pdf) of Overeating saturated fat promotes fatty liver and ceramides compared to polyunsaturated fat: a randomized trial
Part of Molecular Nutrition & Food Research, 2019
Part of Nutrients, 2019
- DOI for An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome-A SYSDIET Sub-Study
- Download full text (pdf) of An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome-A SYSDIET Sub-Study
Fasting hepatic de novo lipogenesis is not reliably assessed using circulating fatty acid markers
Part of American Journal of Clinical Nutrition, p. 260-268, 2019
Acute caloric restriction counteracts hepatic bile acid and cholesterol deficiency in morbid obesity
Part of Journal of Internal Medicine, p. 507-517, 2017
- DOI for Acute caloric restriction counteracts hepatic bile acid and cholesterol deficiency in morbid obesity
- Download full text (pdf) of Acute caloric restriction counteracts hepatic bile acid and cholesterol deficiency in morbid obesity
Part of American Journal of Clinical Nutrition, p. 991-1000, 2017
Part of Annals of Nutrition and Metabolism, p. 372-372, 2017
Part of Journal of Nutrition, p. 2118-2125, 2017
Part of Lipids in Health and Disease, p. 1-10, 2017
- DOI for Fatty acid composition in serum cholesterol esters and phospholipids is linked to visceral and subcutaneous adipose tissue content in elderly individuals: a cross-sectional study
- Download full text (pdf) of Fatty acid composition in serum cholesterol esters and phospholipids is linked to visceral and subcutaneous adipose tissue content in elderly individuals: a cross-sectional study
Part of International Journal of Obesity, p. 1295-1298, 2017
- DOI for Depot-specific differences in fatty acid composition and distinct associations with lipogenic gene expression in abdominal adipose tissue of obese women
- Download full text (pdf) of Depot-specific differences in fatty acid composition and distinct associations with lipogenic gene expression in abdominal adipose tissue of obese women
Part of Journal of Nutrition, p. 662-672, 2016
Part of ATHEROSCLEROSIS, 2016
Part of Genes & Nutrition, 2016
- DOI for Effects of a healthy Nordic diet on gene expression changes in peripheral blood mononuclear cells in response to an oral glucose tolerance test in subjects with metabolic syndrome: a SYSDIET sub-study
- Download full text (pdf) of Effects of a healthy Nordic diet on gene expression changes in peripheral blood mononuclear cells in response to an oral glucose tolerance test in subjects with metabolic syndrome: a SYSDIET sub-study
Part of Diabetologia, p. 799-812, 2016
Part of American Journal of Clinical Nutrition, p. 20-30, 2015
Metabolomic response to Nordic foods
Part of Annals of Nutrition and Metabolism, p. 55-55, 2015
Part of Nutrition & Diabetes, 2015
- DOI for NMR-based metabolic profiling in healthy individuals overfed different types of fat: links to changes in liver fat accumulation and lean tissue mass.
- Download full text (pdf) of NMR-based metabolic profiling in healthy individuals overfed different types of fat: links to changes in liver fat accumulation and lean tissue mass.
Part of Lipids in Health and Disease, 2015
- DOI for Saturated fatty acids in human visceral adipose tissue are associated with increased 11-beta-hydroxysteroid-dehydrogenase type 1 expression
- Download full text (pdf) of Saturated fatty acids in human visceral adipose tissue are associated with increased 11-beta-hydroxysteroid-dehydrogenase type 1 expression
Part of American Journal of Clinical Nutrition, p. 228-239, 2015
Part of Journal of the American Heart Association, 2014
- DOI for Role of Dietary Fats in Modulating Cardiometabolic Risk During Moderate Weight Gain: A Randomized Double-Blind Overfeeding Trial (LIPOGAIN Study)
- Download full text (pdf) of Role of Dietary Fats in Modulating Cardiometabolic Risk During Moderate Weight Gain: A Randomized Double-Blind Overfeeding Trial (LIPOGAIN Study)
Part of Journal of Nutrition, p. 1642-1649, 2014
Part of European Journal of Nutrition, p. 1123-1134, 2014
Part of PLOS ONE, 2014
- DOI for Whole Grain Rye Intake, Reflected by a Biomarker, Is Associated with Favorable Blood Lipid Outcomes in Subjects with the Metabolic Syndrome: A Randomized Study
- Download full text (pdf) of Whole Grain Rye Intake, Reflected by a Biomarker, Is Associated with Favorable Blood Lipid Outcomes in Subjects with the Metabolic Syndrome: A Randomized Study
Part of Diabetes, p. 2356-2368, 2014
Part of European Journal of Clinical Nutrition, p. 453-458, 2014
Part of Journal of Internal Medicine, p. 52-66, 2013
- DOI for Effects of an isocaloric healthy Nordic diet on insulin sensitivity, lipid profile and inflammation markers in metabolic syndrome: a randomized study (SYSDIET)
- Download full text (pdf) of Effects of an isocaloric healthy Nordic diet on insulin sensitivity, lipid profile and inflammation markers in metabolic syndrome: a randomized study (SYSDIET)
Alkylresorcinols And A-Carotene In Plasma As Dietary Biomarkers For Healthy Nordic Diet
Part of Annals of Nutrition and Metabolism, p. 459-459, 2013
Plasma Alkylresorcinols Reflect Important Whole-Grain Components of a Healthy Nordic Diet
Part of Journal of Nutrition, p. 1383-1390, 2013
Articles, review/survey
Fats and oils: a scoping review for Nordic Nutrition Recommendations 2023
Part of Food & Nutrition Research, 2024
- DOI for Fats and oils: a scoping review for Nordic Nutrition Recommendations 2023
- Download full text (pdf) of Fats and oils: a scoping review for Nordic Nutrition Recommendations 2023
Fat and fatty acids: a scoping review for Nordic Nutrition Recommendations 2023
Part of Food & Nutrition Research, 2024
- DOI for Fat and fatty acids: a scoping review for Nordic Nutrition Recommendations 2023
- Download full text (pdf) of Fat and fatty acids: a scoping review for Nordic Nutrition Recommendations 2023
Part of Clinical Nutrition, p. 915-925, 2024
- DOI for Glycemic variability assessed using continuous glucose monitoring in individuals without diabetes and associations with cardiometabolic risk markers: A systematic review and meta-analysis
- Download full text (pdf) of Glycemic variability assessed using continuous glucose monitoring in individuals without diabetes and associations with cardiometabolic risk markers: A systematic review and meta-analysis
2020
- DOI for The Effects of Foods on Blood Lipids in Non-alcoholic Fatty Liver Disease (NAFLD)-A Systematic Review and Meta-Analysis
- Download full text (pdf) of The Effects of Foods on Blood Lipids in Non-alcoholic Fatty Liver Disease (NAFLD)-A Systematic Review and Meta-Analysis
Part of Hormone Molecular Biology and Clinical Investigation, 2020