Gang Pan

Gain-of-function enhancer variant near KCNB1 causes familial ST-depression syndrome

Christensen, Alex Horby; Pan, Gang; Marvig, Rasmus L.; Gonzalez, Francisco German Rodriguez et al.

Part of European Heart Journal, p. 3486-3497, 2025

• DOI for Gain-of-function enhancer variant near KCNB1 causes familial ST-depression syndrome

Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues

Diamanti, Klev; Cavalli, Marco; Pereira, Maria J.; Pan, Gang et al.

Part of Cell Reports Medicine, 2022

• DOI for Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues
• Download full text (pdf) of Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues

Multifaceted regulation of hepatic lipid metabolism by YY1

Pan, Gang; Diamanti, Klev; Cavalli, Marco; Gutierrez, Ariadna Lara et al.

Part of Life Science Alliance, 2021

• DOI for Multifaceted regulation of hepatic lipid metabolism by YY1
• Download full text (pdf) of Multifaceted regulation of hepatic lipid metabolism by YY1

The Thioesterase ACOT1 as a Regulator of Lipid Metabolism in Type 2 Diabetes Detected in a Multi-Omics Study of Human Liver

Cavalli, Marco; Diamanti, Klev; Dang, Yonglong; Xing, Pengwei et al.

Part of Omics, p. 652-659, 2021

• DOI for The Thioesterase ACOT1 as a Regulator of Lipid Metabolism in Type 2 Diabetes Detected in a Multi-Omics Study of Human Liver
• Download full text (pdf) of The Thioesterase ACOT1 as a Regulator of Lipid Metabolism in Type 2 Diabetes Detected in a Multi-Omics Study of Human Liver

Single nucleus transcriptomics data integration recapitulates the major cell types in human liver

Diamanti, Klev; Inda Díaz, Juan Salvador; Raine, Amanda; Pan, Gang et al.

Part of Hepatology Research, p. 233-238, 2021

• DOI for Single nucleus transcriptomics data integration recapitulates the major cell types in human liver
• Download full text (pdf) of Single nucleus transcriptomics data integration recapitulates the major cell types in human liver

Gain-of-function enhancer variant near KCNB1 causes familial ST-depression syndrome

Christensen, Alex Horby; Pan, Gang; Marvig, Rasmus L.; Gonzalez, Francisco German Rodriguez et al.

Part of European Heart Journal, p. 3486-3497, 2025

• DOI for Gain-of-function enhancer variant near KCNB1 causes familial ST-depression syndrome

Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues

Diamanti, Klev; Cavalli, Marco; Pereira, Maria J.; Pan, Gang et al.

Part of Cell Reports Medicine, 2022

• DOI for Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues
• Download full text (pdf) of Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues

Multifaceted regulation of hepatic lipid metabolism by YY1

Pan, Gang; Diamanti, Klev; Cavalli, Marco; Gutierrez, Ariadna Lara et al.

Part of Life Science Alliance, 2021

• DOI for Multifaceted regulation of hepatic lipid metabolism by YY1
• Download full text (pdf) of Multifaceted regulation of hepatic lipid metabolism by YY1

The Thioesterase ACOT1 as a Regulator of Lipid Metabolism in Type 2 Diabetes Detected in a Multi-Omics Study of Human Liver

Cavalli, Marco; Diamanti, Klev; Dang, Yonglong; Xing, Pengwei et al.

Part of Omics, p. 652-659, 2021

• DOI for The Thioesterase ACOT1 as a Regulator of Lipid Metabolism in Type 2 Diabetes Detected in a Multi-Omics Study of Human Liver
• Download full text (pdf) of The Thioesterase ACOT1 as a Regulator of Lipid Metabolism in Type 2 Diabetes Detected in a Multi-Omics Study of Human Liver

Single nucleus transcriptomics data integration recapitulates the major cell types in human liver

Diamanti, Klev; Inda Díaz, Juan Salvador; Raine, Amanda; Pan, Gang et al.

Part of Hepatology Research, p. 233-238, 2021

• DOI for Single nucleus transcriptomics data integration recapitulates the major cell types in human liver
• Download full text (pdf) of Single nucleus transcriptomics data integration recapitulates the major cell types in human liver

Interpretable Machine Learning Reveals Dissimilarities Between Subtypes of Autism Spectrum Disorder

Garbulowski, Mateusz; Smolinska Garbulowska, Karolina; Diamanti, Klev; Pan, Gang et al.

Part of Frontiers in Genetics, 2021

• DOI for Interpretable Machine Learning Reveals Dissimilarities Between Subtypes of Autism Spectrum Disorder
• Download full text (pdf) of Interpretable Machine Learning Reveals Dissimilarities Between Subtypes of Autism Spectrum Disorder

Polymorphisms rs55710213 and rs56334587 regulate SCD1 expression by modulating HNF4A binding

Pan, Gang; Cavalli, Marco; Wadelius, Claes

Part of Biochimica et Biophysica Acta. Gene Regulatory Mechanisms, 2021

• DOI for Polymorphisms rs55710213 and rs56334587 regulate SCD1 expression by modulating HNF4A binding
• Download full text (pdf) of Polymorphisms rs55710213 and rs56334587 regulate SCD1 expression by modulating HNF4A binding

Integration of whole-body [¹⁸F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes

Diamanti, Klev; Visvanathar, Robin; Pereira, Maria J.; Cavalli, Marco et al.

Part of Scientific Reports, 2020

• DOI for Integration of whole-body [¹⁸F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes
• Download full text (pdf) of Integration of whole-body [¹⁸F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes

A Multi-Omics Approach to Liver Diseases: Integration of Single Nuclei Transcriptomics with Proteomics and HiCap Bulk Data in Human Liver

Cavalli, Marco; Diamanti, Klev; Pan, Gang; Spalinskas, Rapolas et al.

Part of Omics, p. 180-194, 2020

• DOI for A Multi-Omics Approach to Liver Diseases: Integration of Single Nuclei Transcriptomics with Proteomics and HiCap Bulk Data in Human Liver
• Download full text (pdf) of A Multi-Omics Approach to Liver Diseases: Integration of Single Nuclei Transcriptomics with Proteomics and HiCap Bulk Data in Human Liver

rs953413 Regulates Polyunsaturated Fatty Acid Metabolism by Modulating ELOVL2 Expression

Pan, Gang; Cavalli, Marco; Carlsson, Björn; Skrtic, Stanko et al.

Part of iScience, 2020

• DOI for rs953413 Regulates Polyunsaturated Fatty Acid Metabolism by Modulating ELOVL2 Expression
• Download full text (pdf) of rs953413 Regulates Polyunsaturated Fatty Acid Metabolism by Modulating ELOVL2 Expression

Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease.

Karlsson, Torgny; Rask-Andersen, Mathias; Pan, Gang; Höglund, Julia et al.

Part of Nature Medicine, p. 1390-1395, 2019

• DOI for Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease.

Allele specific chromatin signals, 3D interactions, and motif predictions for immune and B cell related diseases

Cavalli, Marco; Baltzer, Nicholas; Umer, Husen Muhammad; Grau, Jan et al.

Part of Scientific Reports, 2019

• DOI for Allele specific chromatin signals, 3D interactions, and motif predictions for immune and B cell related diseases
• Download full text (pdf) of Allele specific chromatin signals, 3D interactions, and motif predictions for immune and B cell related diseases

Studies of liver tissue identify functional gene regulatory elements associated to gene expression, type 2 diabetes, and other metabolic diseases

Cavalli, Marco; Baltzer, Nicholas; Pan, Gang; Walls, Jose Ramon Barcenas et al.

Part of Human Genomics, 2019

• DOI for Studies of liver tissue identify functional gene regulatory elements associated to gene expression, type 2 diabetes, and other metabolic diseases
• Download full text (pdf) of Studies of liver tissue identify functional gene regulatory elements associated to gene expression, type 2 diabetes, and other metabolic diseases

Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes

Diamanti, Klev; Cavalli, Marco; Pan, Gang; Pereira, Maria J et al.

Part of Scientific Reports, 2019

• DOI for Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes
• Download full text (pdf) of Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes

Genetic prevention of hepatitis C virus-induced liver fibrosis by allele-specific downregulation of MERTK

Cavalli, Marco; Pan, Gang; Nord, Helena; Wallén Arzt, Emelie et al.

Part of Hepatology Research, p. 826-830, 2017

• DOI for Genetic prevention of hepatitis C virus-induced liver fibrosis by allele-specific downregulation of MERTK

PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c

Pan, Gang; Ameur, Adam; Enroth, Stefan; Bysani, Madhusudhan et al.

Part of Nucleic Acids Research, p. 2408-2422, 2017

• DOI for PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c

Looking beyond GWAS: allele-specific transcription factor binding drives the association of GALNT2 to HDL-C plasma levels

Cavalli, Marco; Pan, Gang; Nord, Helena; Wadelius, Claes

Part of Lipids in Health and Disease, 2016

• DOI for Looking beyond GWAS: allele-specific transcription factor binding drives the association of GALNT2 to HDL-C plasma levels
• Download full text (pdf) of Looking beyond GWAS: allele-specific transcription factor binding drives the association of GALNT2 to HDL-C plasma levels

Allele-specific transcription factor binding in liver and cervix cells unveils many likely drivers of GWAS signals

Cavalli, Marco; Pan, Gang; Nord, Helena; Arzt, Emelie Wallén et al.

Part of Genomics, p. 248-254, 2016

• DOI for Allele-specific transcription factor binding in liver and cervix cells unveils many likely drivers of GWAS signals
• Download full text (pdf) of Allele-specific transcription factor binding in liver and cervix cells unveils many likely drivers of GWAS signals

Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression

Cavalli, Marco; Pan, Gang; Nord, Helena; Wallerman, Ola et al.

Part of Human Genetics, p. 485-497, 2016

• DOI for Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression
• Download full text (pdf) of Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression

Novel regulatory variant detected on the VKORC1 haplotype that is associated with warfarin dose

Cavalli, Marco; Pan, Gang; Nord, Helena; Eriksson, Niclas et al.

Part of Pharmacogenomics (London), p. 1305-1314, 2016

• DOI for Novel regulatory variant detected on the VKORC1 haplotype that is associated with warfarin dose
• Download full text (pdf) of Novel regulatory variant detected on the VKORC1 haplotype that is associated with warfarin dose

A Significant Regulatory Mutation Burden at a High-Affinity Position of the CTCF Motif in Gastrointestinal Cancers

Umer, Husen M.; Cavalli, Marco; Dabrowski, Michal J.; Diamanti, Klev et al.

Part of Human Mutation, p. 904-913, 2016

• DOI for A Significant Regulatory Mutation Burden at a High-Affinity Position of the CTCF Motif in Gastrointestinal Cancers

Single Nuclei Transcriptome Analysis of Human Liver with Integration of Proteomics and Capture Hi-C Bulk Tissue Data

Cavalli, Marco; Diamanti, Klev; Pan, Gang; Rapolas, Spalinskas et al.

Integration of whole-body PET/MRI with non-targeted metabolomics provides new insights into insulin sensitivity of various tissues

Diamanti, Klev; Visvanathar, Robin; Pereira, Maria J; Cavalli, Marco et al.