Aljona Saleh

Keywords

• adme
• analytical chemistry
• bioanalysis
• biopharmaceutics
• chromatography
• drug discovery and development platform scilifelab
• high resolution mass spectromentry
• mass spectrometry
• udopp

Publications

Recent publications

• An Adaptable Antibody-Based Platform for Flexible Synthetic Peptide Delivery Built on Agonistic CD40 Antibodies (2022)
• Simple and rapid quantification of cetirizine, venlafaxine, and O-desmethylvenlafaxine in human breast milk, and metformin in human milk and plasma with UHPLC-MS/MS (2022)
• Optimization of Tetrahydroindazoles as Inhibitors of Human Dihydroorotate Dehydrogenase and Evaluation of Their Activity and In Vitro Metabolic Stability (2020)
• A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage (2018)
• Validation and development of MTH1 inhibitors for treatment of cancer (2016)

All publications

Articles

• An Adaptable Antibody-Based Platform for Flexible Synthetic Peptide Delivery Built on Agonistic CD40 Antibodies (2022)
• Simple and rapid quantification of cetirizine, venlafaxine, and O-desmethylvenlafaxine in human breast milk, and metformin in human milk and plasma with UHPLC-MS/MS (2022)
• Optimization of Tetrahydroindazoles as Inhibitors of Human Dihydroorotate Dehydrogenase and Evaluation of Their Activity and In Vitro Metabolic Stability (2020)
• A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage (2018)
• Validation and development of MTH1 inhibitors for treatment of cancer (2016)
• A bioanalytical method for quantification of thioredoxins in Bacillus anthracis by digestion with immobilized pepsin and LC-MS/MS and on-line LC/LC-MS/MS (2016)
• MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool (2014)