Anastasia Emmanouilidou

Genome-wide interaction study with body mass index identifies CYP7A1 and GIPR as genetic modulators of metabolic dysfunction-associated steatotic liver disease

Jamialahmadi, Oveis; Mujica, Endrina; Morris, Lowri; Mancina, Rosellina Margherita et al.

Part of Clinical and Molecular Hepatology, p. 1252-1268, 2025

• DOI for Genome-wide interaction study with body mass index identifies CYP7A1 and GIPR as genetic modulators of metabolic dysfunction-associated steatotic liver disease
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Telmisartan reverses hepatic steatosis via PCK1 upregulation: A novel PPAR-independent mechanism in experimental models of MASLD

Bentanachs, Roger; Ramirez-Carrasco, Patricia; Braster, Bianca; Emmanouilidou, Anastasia et al.

Part of Pharmacological Research, 2025

• DOI for Telmisartan reverses hepatic steatosis via PCK1 upregulation: A novel PPAR-independent mechanism in experimental models of MASLD
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Functionally characterizing obesity-susceptibility genes using CRISPR/Cas9, in vivo imaging and deep learning.

Mazzaferro, Eugenia; Mujica, Endrina; Zhang, Hanqing; Emmanouilidou, Anastasia et al.

Part of Scientific Reports, p. 5408, 2025

• DOI for Functionally characterizing obesity-susceptibility genes using CRISPR/Cas9, in vivo imaging and deep learning.
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CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations

Höijer, Ida; Emmanouilidou, Anastasia; Östlund, Rebecka; van Schendel, Robin et al.

Part of Nature Communications, 2022

• DOI for CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations
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Dysregulation of macrophage PEPD in obesity determines adipose tissue fibro-inflammation and insulin resistance

Pellegrinelli, V; Rodriguez-Cuenca, S.; Rouault, C.; Figueroa-Juarez, E. et al.

Part of Nature Metabolism, p. 476-+, 2022

• DOI for Dysregulation of macrophage PEPD in obesity determines adipose tissue fibro-inflammation and insulin resistance

Genome-wide interaction study with body mass index identifies CYP7A1 and GIPR as genetic modulators of metabolic dysfunction-associated steatotic liver disease

Jamialahmadi, Oveis; Mujica, Endrina; Morris, Lowri; Mancina, Rosellina Margherita et al.

Part of Clinical and Molecular Hepatology, p. 1252-1268, 2025

• DOI for Genome-wide interaction study with body mass index identifies CYP7A1 and GIPR as genetic modulators of metabolic dysfunction-associated steatotic liver disease
• Download full text (pdf) of Genome-wide interaction study with body mass index identifies CYP7A1 and GIPR as genetic modulators of metabolic dysfunction-associated steatotic liver disease

Telmisartan reverses hepatic steatosis via PCK1 upregulation: A novel PPAR-independent mechanism in experimental models of MASLD

Bentanachs, Roger; Ramirez-Carrasco, Patricia; Braster, Bianca; Emmanouilidou, Anastasia et al.

Part of Pharmacological Research, 2025

• DOI for Telmisartan reverses hepatic steatosis via PCK1 upregulation: A novel PPAR-independent mechanism in experimental models of MASLD
• Download full text (pdf) of Telmisartan reverses hepatic steatosis via PCK1 upregulation: A novel PPAR-independent mechanism in experimental models of MASLD

Functionally characterizing obesity-susceptibility genes using CRISPR/Cas9, in vivo imaging and deep learning.

Mazzaferro, Eugenia; Mujica, Endrina; Zhang, Hanqing; Emmanouilidou, Anastasia et al.

Part of Scientific Reports, p. 5408, 2025

• DOI for Functionally characterizing obesity-susceptibility genes using CRISPR/Cas9, in vivo imaging and deep learning.
• Download full text (pdf) of Functionally characterizing obesity-susceptibility genes using CRISPR/Cas9, in vivo imaging and deep learning.

CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations

Höijer, Ida; Emmanouilidou, Anastasia; Östlund, Rebecka; van Schendel, Robin et al.

Part of Nature Communications, 2022

• DOI for CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations
• Download full text (pdf) of CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations

Dysregulation of macrophage PEPD in obesity determines adipose tissue fibro-inflammation and insulin resistance

Pellegrinelli, V; Rodriguez-Cuenca, S.; Rouault, C.; Figueroa-Juarez, E. et al.

Part of Nature Metabolism, p. 476-+, 2022

• DOI for Dysregulation of macrophage PEPD in obesity determines adipose tissue fibro-inflammation and insulin resistance

Amplification-free long-read sequencing reveals unforeseen CRISPR-Cas9 off-target activity

Höijer, Ida; Johansson, Josefin; Gudmundsson, Sanna; Chin, Chen-Shan et al.

Part of Genome Biology, 2020

• DOI for Amplification-free long-read sequencing reveals unforeseen CRISPR-Cas9 off-target activity
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Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo image- and CRISPR/Cas9-based approach

von der Heyde, Benedikt; Emmanouilidou, Anastasia; Mazzaferro, Eugenia; Vicenzi, Silvia et al.

Part of Scientific Reports, 2020

• DOI for Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo image- and CRISPR/Cas9-based approach
• Download full text (pdf) of Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo image- and CRISPR/Cas9-based approach

Kita crispants for systematic image-based genetic screens of complex traits in zebrafish larvae

Mazzaferro, Eugenia; Metzendorf, Christoph; Zhang, Hanqing; Mujica, Endrina et al.

Characterizing obesity-susceptibility genes using CRISPR/Cas9, in vivo imaging and deep learning

Mazzaferro, Eugenia; Mujica, Endrina; Zhang, Hanqing; Emmanouilidou, Anastasia et al.