Nikolaos Kavalopoulos

Droplet microfluidics with image texture quantification for detection of rare antibiotic-resistant subpopulations from bloodstream infections

Agnihotri, Sagar N.; Fatsis-Kavalopoulos, Nikos; Vikdahl, Emma; Windhager, Jonas et al.

Part of npj Digital Medicine, 2026

• DOI for Droplet microfluidics with image texture quantification for detection of rare antibiotic-resistant subpopulations from bloodstream infections
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Prevalence, misclassification, and clinical consequences of the heteroresistant phenotype in Escherichia coli bloodstream infections in patients in Uppsala, Sweden: a retrospective cohort study

Heyman, Gabriel; Jonsson, Sofia; Fatsis-Kavalopoulos, Nikos; Hjort, Karin et al.

Part of The Lancet Microbe, 2025

• DOI for Prevalence, misclassification, and clinical consequences of the heteroresistant phenotype in Escherichia coli bloodstream infections in patients in Uppsala, Sweden: a retrospective cohort study
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Droplet microfluidics with image texture-based detection of bacterial heteroresistance in isolated from blood stream infections

Agnihotri, Sagar Narhari; Fatsis-Kavalopoulos, Nikos; Vikdahl, Emma; Andersson, Dan I. et al.

2025

Vancomycin heteroresistance (hVISA) in MRSA links to treatment failure and supports a revised PAP-AUC threshold

Fatsis-Kavalopoulos, Nikos; Kim, Yong Kyun; Chong, Yong Pil; Bae, Seongman et al.

Part of Nature Communications, 2025

• DOI for Vancomycin heteroresistance (hVISA) in MRSA links to treatment failure and supports a revised PAP-AUC threshold
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Heteroresistance and clinical outcomes: much still to be understood – Authors' reply

Fatsis-Kavalopoulos, Nikos; Heyman, Gabriel; Hjort, Karin; Jonsson, Sofia et al.

Part of The Lancet Microbe, 2025

• DOI for Heteroresistance and clinical outcomes: much still to be understood – Authors' reply
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Droplet microfluidics with image texture quantification for detection of rare antibiotic-resistant subpopulations from bloodstream infections

Agnihotri, Sagar N.; Fatsis-Kavalopoulos, Nikos; Vikdahl, Emma; Windhager, Jonas et al.

Part of npj Digital Medicine, 2026

• DOI for Droplet microfluidics with image texture quantification for detection of rare antibiotic-resistant subpopulations from bloodstream infections
• Download full text (pdf) of Droplet microfluidics with image texture quantification for detection of rare antibiotic-resistant subpopulations from bloodstream infections

Vancomycin heteroresistance (hVISA) in MRSA links to treatment failure and supports a revised PAP-AUC threshold

Fatsis-Kavalopoulos, Nikos; Kim, Yong Kyun; Chong, Yong Pil; Bae, Seongman et al.

Part of Nature Communications, 2025

• DOI for Vancomycin heteroresistance (hVISA) in MRSA links to treatment failure and supports a revised PAP-AUC threshold
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Heteroresistance and clinical outcomes: much still to be understood – Authors' reply

Fatsis-Kavalopoulos, Nikos; Heyman, Gabriel; Hjort, Karin; Jonsson, Sofia et al.

Part of The Lancet Microbe, 2025

• DOI for Heteroresistance and clinical outcomes: much still to be understood – Authors' reply
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Sublethal interaction factor (SIF), a growth-based method to analyze antibiotic combinations at sub-inhibitory concentrations

Sánchez-Hevia, Dione L.; Fatsis-Kavalopoulos, Nikolaos; Andersson, Dan I.

Part of Microbiology Spectrum, 2025

• DOI for Sublethal interaction factor (SIF), a growth-based method to analyze antibiotic combinations at sub-inhibitory concentrations
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Fast detection of synergy and antagonism in antifungal combinations used against Candida albicans clinical isolates

Lundvik, Hanna; Santini, Ramona; Altintop, Tugce Unalan; Ozenci, Volkan et al.

Part of Scientific Reports, 2025

• DOI for Fast detection of synergy and antagonism in antifungal combinations used against Candida albicans clinical isolates
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Droplet microfluidics-based detection of rare antibiotic-resistant subpopulations in Escherichia coli from bloodstream infections

Agnihotri, Sagar Narhari; Fatsis-Kavalopoulos, Nikos; Windhager, Jonas; Tenje, Maria et al.

Part of Science Advances, 2025

• DOI for Droplet microfluidics-based detection of rare antibiotic-resistant subpopulations in Escherichia coli from bloodstream infections
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CombiANT reader: Deep learning-based automatic image processing tool to robustly quantify antibiotic interactions

Hallström, Erik; Fatsis-Kavalopoulos, Nikos; Bimpis, Manos; Wählby, Carolina et al.

Part of PLOS Digital Health, 2025

• DOI for CombiANT reader: Deep learning-based automatic image processing tool to robustly quantify antibiotic interactions
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Within-species variability of antibiotic interactions in Gram-negative bacteria

Tang, Po-Cheng; Sánchez-Hevia, Dione; Westhoff, Sanne; Fatsis-Kavalopoulos, Nikos et al.

Part of mBio, 2024

• DOI for Within-species variability of antibiotic interactions in Gram-negative bacteria
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Beyond the FIC index: the extended information from fractional inhibitory concentrations (FICs)

Fatsis-Kavalopoulos, Nikos; Sánchez-Hevia, Dione; Andersson, Dan I.

Part of Journal of Antimicrobial Chemotherapy, p. 2394-2396, 2024

• DOI for Beyond the FIC index: the extended information from fractional inhibitory concentrations (FICs)
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Antibiotic use during coronavirus disease 2019 intensive care unit shape multidrug resistance bacteriuria: A Swedish longitudinal prospective study

Karlsson, Philip A.; Pärssinen, Julia; Danielsson, Erik A.; Fatsis-Kavalopoulos, Nikos et al.

Part of Frontiers in Medicine, 2023

• DOI for Antibiotic use during coronavirus disease 2019 intensive care unit shape multidrug resistance bacteriuria: A Swedish longitudinal prospective study
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Piezo1 activation attenuates thrombin-induced blebbing in breast cancer cells

O'Callaghan, Paul; Engberg, Adam; Eriksson, Olle; Fatsis-Kavalopoulos, Nikos et al.

Part of Journal of Cell Science, 2022

• DOI for Piezo1 activation attenuates thrombin-induced blebbing in breast cancer cells
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A Microfluidic Chip for Studies of the Dynamics of Antibiotic Resistance Selection in Bacterial Biofilms

Tang, Po-Cheng; Eriksson, Olle; Sjögren, Josefin; Fatsis-Kavalopoulos, Nikos et al.

Part of Frontiers in Cellular and Infection Microbiology, 2022

• DOI for A Microfluidic Chip for Studies of the Dynamics of Antibiotic Resistance Selection in Bacterial Biofilms
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Potential risks of treating bacterial infections with a combination of β-lactam and aminoglycoside antibiotics: A systematic quantification of antibiotic interactions in E. coli blood stream infection isolates

Fatsis-Kavalopoulos, Nikos; Roelofs, Lex; Andersson, Dan I.

Part of EBioMedicine, 2022

• DOI for Potential risks of treating bacterial infections with a combination of β-lactam and aminoglycoside antibiotics: A systematic quantification of antibiotic interactions in E. coli blood stream infection isolates
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CombiANT: Antibiotic interaction testing made easy

Fatsis-Kavalopoulos, Nikos; Römhild, Roderich; Tang, Po-Cheng; Kreuger, Johan et al.

Part of PLoS biology, 2020

• DOI for CombiANT: Antibiotic interaction testing made easy
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A Multiplex Fluidic Chip for Rapid Phenotypic Antibiotic Susceptibility Testing

Wistrand-Yuen, Pikkei; Malmberg, Christer; Fatsis-Kavalopoulos, Nikos; Lübke, Moritz et al.

Part of mBio, 2020

• DOI for A Multiplex Fluidic Chip for Rapid Phenotypic Antibiotic Susceptibility Testing
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Modular microfluidic systems cast from 3D-printed molds for imaging leukocyte adherence to differentially treated endothelial cultures

Hernández Vera, Rodrigo; O'Callaghan, Paul; Fatsis-Kavalopoulos, Nikos; Kreuger, Johan

Part of Scientific Reports, 2019

• DOI for Modular microfluidic systems cast from 3D-printed molds for imaging leukocyte adherence to differentially treated endothelial cultures
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Formation of precisely composed cancer cell clusters using a cell assembly generator (CAGE) for studying paracrine signaling at single-cell resolution

Fatsis-Kavalopoulos, Nikos; O'Callaghan, Paul; Xie, Beichen; Hernández Vera, Rodrigo et al.

Part of Lab on a Chip, p. 1071-1081, 2019

• DOI for Formation of precisely composed cancer cell clusters using a cell assembly generator (CAGE) for studying paracrine signaling at single-cell resolution
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A Modular and Affordable Time-Lapse Imaging and Incubation System Based on 3D Printed Parts, a Smartphone, and Off-The-Shelf Electronics

Hernández Vera, Rodrigo; Schwan, Emil; Fatsis-Kavalopoulos, Nikos; Kreuger, Johan

Part of PLOS ONE, 2016

• DOI for A Modular and Affordable Time-Lapse Imaging and Incubation System Based on 3D Printed Parts, a Smartphone, and Off-The-Shelf Electronics
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Precise cell manipulations and imaging of cellular responses: Methods developed using microfluidic, 3D-printing and microfabrication technologies

Fatsis-Kavalopoulos, Nikos

2019

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Droplet microfluidics with image texture-based detection of bacterial heteroresistance in isolated from blood stream infections

Agnihotri, Sagar Narhari; Fatsis-Kavalopoulos, Nikos; Vikdahl, Emma; Andersson, Dan I. et al.

2025

Prevalence, misclassification, and clinical consequences of the heteroresistant phenotype in Escherichia coli bloodstream infections in patients in Uppsala, Sweden: a retrospective cohort study

Heyman, Gabriel; Jonsson, Sofia; Fatsis-Kavalopoulos, Nikos; Hjort, Karin et al.

Part of The Lancet Microbe, 2025

• DOI for Prevalence, misclassification, and clinical consequences of the heteroresistant phenotype in Escherichia coli bloodstream infections in patients in Uppsala, Sweden: a retrospective cohort study
• Download full text (pdf) of Prevalence, misclassification, and clinical consequences of the heteroresistant phenotype in Escherichia coli bloodstream infections in patients in Uppsala, Sweden: a retrospective cohort study