Tina Sarén

Pre-clinical safety and efficacy evaluation of Helicobacter Pylori neutrophil-activating protein (NAP)-armed CAR-T cells targeting B cell lymphomas

Ma, Jing; Sarén, Tina; Jin, Chuan; Kim, Hyeong Su et al.

Part of Cancer Immunology and Immunotherapy, 2025

• DOI for Pre-clinical safety and efficacy evaluation of Helicobacter Pylori neutrophil-activating protein (NAP)-armed CAR-T cells targeting B cell lymphomas
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Trogocytosis of chimeric antigen receptors between T cells is regulated by their transmembrane domains

Barbera, Stefano; Schuiling, Matthijs J. A.; Sanjaya, Nathaniel A.; Pietilä, Ilkka et al.

Part of Science immunology, 2025

• DOI for Trogocytosis of chimeric antigen receptors between T cells is regulated by their transmembrane domains

Single-Cell RNA Analysis Reveals Cell-Intrinsic Functions of CAR T Cells Correlating with Response in a Phase II Study of Lymphoma Patients

Sarén, Tina; Ramachandran, Mohanraj; Gammelgård, Gustav; Lövgren, Tanja et al.

Part of Clinical Cancer Research, p. 4139-4152, 2023

• DOI for Single-Cell RNA Analysis Reveals Cell-Intrinsic Functions of CAR T Cells Correlating with Response in a Phase II Study of Lymphoma Patients
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Complementarity-determining region clustering may cause CAR-T cell dysfunction

Sarén, Tina; Saronio, Giulia; Marti Torrell, Paula; Zhu, Xu et al.

Part of Nature Communications, 2023

• DOI for Complementarity-determining region clustering may cause CAR-T cell dysfunction
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Whole body FDG PET/MR for progression free and overall survival prediction in patients with relapsed/refractory large B-cell lymphomas undergoing CAR T-cell therapy

Sjöholm, Therese; Korenyushkin, Alexander; Gammelgård, Gustav; Sarén, Tina et al.

Part of Cancer Imaging, 2022

• DOI for Whole body FDG PET/MR for progression free and overall survival prediction in patients with relapsed/refractory large B-cell lymphomas undergoing CAR T-cell therapy
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Pre-clinical safety and efficacy evaluation of Helicobacter Pylori neutrophil-activating protein (NAP)-armed CAR-T cells targeting B cell lymphomas

Ma, Jing; Sarén, Tina; Jin, Chuan; Kim, Hyeong Su et al.

Part of Cancer Immunology and Immunotherapy, 2025

• DOI for Pre-clinical safety and efficacy evaluation of Helicobacter Pylori neutrophil-activating protein (NAP)-armed CAR-T cells targeting B cell lymphomas
• Download full text (pdf) of Pre-clinical safety and efficacy evaluation of Helicobacter Pylori neutrophil-activating protein (NAP)-armed CAR-T cells targeting B cell lymphomas

Trogocytosis of chimeric antigen receptors between T cells is regulated by their transmembrane domains

Barbera, Stefano; Schuiling, Matthijs J. A.; Sanjaya, Nathaniel A.; Pietilä, Ilkka et al.

Part of Science immunology, 2025

• DOI for Trogocytosis of chimeric antigen receptors between T cells is regulated by their transmembrane domains

Single-Cell RNA Analysis Reveals Cell-Intrinsic Functions of CAR T Cells Correlating with Response in a Phase II Study of Lymphoma Patients

Sarén, Tina; Ramachandran, Mohanraj; Gammelgård, Gustav; Lövgren, Tanja et al.

Part of Clinical Cancer Research, p. 4139-4152, 2023

• DOI for Single-Cell RNA Analysis Reveals Cell-Intrinsic Functions of CAR T Cells Correlating with Response in a Phase II Study of Lymphoma Patients
• Download full text (pdf) of Single-Cell RNA Analysis Reveals Cell-Intrinsic Functions of CAR T Cells Correlating with Response in a Phase II Study of Lymphoma Patients

Complementarity-determining region clustering may cause CAR-T cell dysfunction

Sarén, Tina; Saronio, Giulia; Marti Torrell, Paula; Zhu, Xu et al.

Part of Nature Communications, 2023

• DOI for Complementarity-determining region clustering may cause CAR-T cell dysfunction
• Download full text (pdf) of Complementarity-determining region clustering may cause CAR-T cell dysfunction

Whole body FDG PET/MR for progression free and overall survival prediction in patients with relapsed/refractory large B-cell lymphomas undergoing CAR T-cell therapy

Sjöholm, Therese; Korenyushkin, Alexander; Gammelgård, Gustav; Sarén, Tina et al.

Part of Cancer Imaging, 2022

• DOI for Whole body FDG PET/MR for progression free and overall survival prediction in patients with relapsed/refractory large B-cell lymphomas undergoing CAR T-cell therapy
• Download full text (pdf) of Whole body FDG PET/MR for progression free and overall survival prediction in patients with relapsed/refractory large B-cell lymphomas undergoing CAR T-cell therapy

Tumor-Targeted Delivery of the p53-Activating Peptide VIP116 with PEG-Stabilized Lipodisks

Lundsten, Sara; Hernandez, Victor Agmo; Gedda, Lars; Sarén, Tina et al.

Part of Nanomaterials, 2020

• DOI for Tumor-Targeted Delivery of the p53-Activating Peptide VIP116 with PEG-Stabilized Lipodisks
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Insertion of the Type-I IFN Decoy Receptor B18R in a miRNA-Tagged Semliki Forest Virus Improves Oncolytic Capacity but Results in Neurotoxicity

Sarén, Tina; Ramachandran, Mohanraj; Martikainen, Miika; Yu, Di

Part of MOLECULAR THERAPY-ONCOLYTICS, p. 67-75, 2017

• DOI for Insertion of the Type-I IFN Decoy Receptor B18R in a miRNA-Tagged Semliki Forest Virus Improves Oncolytic Capacity but Results in Neurotoxicity
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CAR T cells for Immunotherapy of Cancer

Sarén, Tina

2022

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Supplementary information - Armed CAR-T cells directed against IL13Ra2 show potent activity against glioblastoma

Sarén, Tina

2022

Supplementary information - Table 8 - Single-cell RNA analysis reveal subpopulations of CAR T cells correlating with response in lymphoma patients

Sarén, Tina

2022

Supplementary information - Single-cell RNA analysis reveal subpopulations of CAR T cells correlating with response in lymphoma patients

Sarén, Tina

2022

Supplementary information -  Complementary determining region clustering causes CAR-T cell dysfunction

Sarén, Tina

2022

Single-cell RNA analysis reveal subpopulations of CAR T cells correlating with response in lymphoma patients

Sarén, Tina; Ramachandran, Mohanraj; Gammelgård, Gustav; Lövgren, Tanja et al.

Armed CAR-T cells directed against IL13Rα2 show potent activity against glioblastoma

Sarén, Tina; Ramachandran, Mohanraj; Saronio, Giulia; Thelander, Josefin et al.

Preclinical evaluation of CAR20(NAP)-T cells for B cell lymphoma

Sarén, Tina; Ma, Jing; Jin, Chuan; Kim, Hyeongsu et al.

Complementary-determining region clustering causes CAR-T cell dysfunction

Sarén, Tina; Saronio, Giulia; Zhu, Xu; Thelander, Josefin et al.

CRISPR/Cas9 as a tool to disrupt wild-type and A53T SNCA in sporadic and familial Parkinson’s disease

Molisak, Agnieszka; Konstantinidis, Evangelos; Aguilar, Ximena; Giedraitis, Vilmantas et al.