Ahmed Mohammed Alsehli

The Cognitive Effects of Statins are Modified by Age

Alsehli, Ahmed M.; Olivo, Gaia; Clemensson, Laura Emily; Williams, Michael J. et al.

Part of Scientific Reports, 2020

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Off-target effects of statins: molecular mechanisms, side effects and the emerging role of kinases

Lagunas-Rangel, Francisco Alejandro; Liepinsh, Edgars; Fredriksson, Robert; Alsehli, Ahmed M. et al.

Part of British Journal of Pharmacology, p. 3799-3818, 2024

• DOI for Off-target effects of statins: molecular mechanisms, side effects and the emerging role of kinases
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Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes

Al-Sabri, Mohamed H.; Ammar, Nourhane; Korzh, Stanislava; Alsehli, Ahmed M. et al.

Part of Scientific Reports, 2024

• DOI for Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes
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The Statin Target HMG-Coenzyme a Reductase (Hmgcr) Regulates Sleep Homeostasis in Drosophila

Alsehli, Ahmed M.; Liao, Sifang; Al-Sabri, Mohamed H.; Vasionis, Lukas et al.

Part of Pharmaceuticals, 2022

• DOI for The Statin Target HMG-Coenzyme a Reductase (Hmgcr) Regulates Sleep Homeostasis in Drosophila
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The Statin Target Hmgcr Regulates Energy Metabolism and Food Intake through Central Mechanisms

Williams, Michael J.; Alsehli, Ahmed M.; Gartner, Sarah N.; Clemensson, Laura Emily et al.

Part of Cells, 2022

• DOI for The Statin Target Hmgcr Regulates Energy Metabolism and Food Intake through Central Mechanisms
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Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes

Al-Sabri, Mohamed H.; Behare, Neha; Alsehli, Ahmed M.; Berkins, Samuel et al.

Part of Cells, 2022

• DOI for Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes
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Off-target effects of statins: molecular mechanisms, side effects and the emerging role of kinases

Lagunas-Rangel, Francisco Alejandro; Liepinsh, Edgars; Fredriksson, Robert; Alsehli, Ahmed M. et al.

Part of British Journal of Pharmacology, p. 3799-3818, 2024

• DOI for Off-target effects of statins: molecular mechanisms, side effects and the emerging role of kinases
• Download full text (pdf) of Off-target effects of statins: molecular mechanisms, side effects and the emerging role of kinases

Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes

Al-Sabri, Mohamed H.; Ammar, Nourhane; Korzh, Stanislava; Alsehli, Ahmed M. et al.

Part of Scientific Reports, 2024

• DOI for Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes
• Download full text (pdf) of Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes

The Statin Target HMG-Coenzyme a Reductase (Hmgcr) Regulates Sleep Homeostasis in Drosophila

Alsehli, Ahmed M.; Liao, Sifang; Al-Sabri, Mohamed H.; Vasionis, Lukas et al.

Part of Pharmaceuticals, 2022

• DOI for The Statin Target HMG-Coenzyme a Reductase (Hmgcr) Regulates Sleep Homeostasis in Drosophila
• Download full text (pdf) of The Statin Target HMG-Coenzyme a Reductase (Hmgcr) Regulates Sleep Homeostasis in Drosophila

The Statin Target Hmgcr Regulates Energy Metabolism and Food Intake through Central Mechanisms

Williams, Michael J.; Alsehli, Ahmed M.; Gartner, Sarah N.; Clemensson, Laura Emily et al.

Part of Cells, 2022

• DOI for The Statin Target Hmgcr Regulates Energy Metabolism and Food Intake through Central Mechanisms
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Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes

Al-Sabri, Mohamed H.; Behare, Neha; Alsehli, Ahmed M.; Berkins, Samuel et al.

Part of Cells, 2022

• DOI for Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes
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Differential associations of statin treatment and polymorphism in genes coding for HMGCR and PCSK9 to risk for insomnia

Alsehli, Ahmed M.; Clemensson, Laura Emily; Rukh, Gull; Ciuculete, Diana-Maria et al.

Part of Frontiers in Bioscience-Landmark, p. 1453-1463, 2021

• DOI for Differential associations of statin treatment and polymorphism in genes coding for HMGCR and PCSK9 to risk for insomnia
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The Cognitive Effects of Statins are Modified by Age

Alsehli, Ahmed M.; Olivo, Gaia; Clemensson, Laura Emily; Williams, Michael J. et al.

Part of Scientific Reports, 2020

• DOI for The Cognitive Effects of Statins are Modified by Age
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The role of HMG-coenzyme A reductase (HMGCR) and statin medication in the Central Nervous System: Cognitive Functions, Metabolism, Feeding and Sleep Behaviour

Alsehli, Ahmed

2021

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The statin target Hmgcr regulates energy metabolism and food intake through central mechanisms in Drosophila

Williams, Michael J.; Alsehli, Ahmed M.; Gartner, Sarah; Clemensson, Laura Emily et al.