Michael Fridén
Associated Researcher at Department of Public Health and Caring Sciences; Clinical Nutrition and Metabolism
- E-mail:
- michael.friden@uu.se
- Visiting address:
- Husargatan 3, BMC
751 22 Uppsala - Postal address:
- Husargatan 3, BMC, Box 564
751 22 UPPSALA
Short presentation
Overall aim of my PhD project:
To increase the knowledge on the role of tissue and plasma fatty acid composition and diet in non-alcoholic fatty liver disease (NAFLD) and its implications for type 2 diabetes.

Publications
Recent publications
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Part of BMC Medicine, 2026
- DOI for Public health policy should be grounded in established evidence that acknowledges uncertainty: a response to The Lancet series on ultra-processed foods
- Download full text (pdf) of Public health policy should be grounded in established evidence that acknowledges uncertainty: a response to The Lancet series on ultra-processed foods
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Part of BMC Medicine, 2026
- DOI for A systematic review of ultra-processed food subtypes and risk of type 2 diabetes, combined with a cohort analysis, question the utility of broad food classifications for public health policy
- Download full text (pdf) of A systematic review of ultra-processed food subtypes and risk of type 2 diabetes, combined with a cohort analysis, question the utility of broad food classifications for public health policy
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Food Substitution Modeling Approaches: A Methodological Study
Part of Current Developments in Nutrition, 2026
- DOI for Food Substitution Modeling Approaches: A Methodological Study
- Download full text (pdf) of Food Substitution Modeling Approaches: A Methodological Study
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Part of The Lancet Planetary Health, 2026
- DOI for (Mis)interpreting substitution models in nutritional epidemiology: why the effect of NOVA 1 foods cannot be understood without NOVA 4
- Download full text (pdf) of (Mis)interpreting substitution models in nutritional epidemiology: why the effect of NOVA 1 foods cannot be understood without NOVA 4
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Cardiometabolic benefits of replacing saturated fatty acids with unsaturated fatty acids
Part of Current opinion in clinical nutrition and metabolic care, p. 131-135, 2026
All publications
Articles in journal
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Part of BMC Medicine, 2026
- DOI for Public health policy should be grounded in established evidence that acknowledges uncertainty: a response to The Lancet series on ultra-processed foods
- Download full text (pdf) of Public health policy should be grounded in established evidence that acknowledges uncertainty: a response to The Lancet series on ultra-processed foods
-
Food Substitution Modeling Approaches: A Methodological Study
Part of Current Developments in Nutrition, 2026
- DOI for Food Substitution Modeling Approaches: A Methodological Study
- Download full text (pdf) of Food Substitution Modeling Approaches: A Methodological Study
-
Part of The Lancet Planetary Health, 2026
- DOI for (Mis)interpreting substitution models in nutritional epidemiology: why the effect of NOVA 1 foods cannot be understood without NOVA 4
- Download full text (pdf) of (Mis)interpreting substitution models in nutritional epidemiology: why the effect of NOVA 1 foods cannot be understood without NOVA 4
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Cardiometabolic benefits of replacing saturated fatty acids with unsaturated fatty acids
Part of Current opinion in clinical nutrition and metabolic care, p. 131-135, 2026
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Part of Nature Communications, 2025
- DOI for Effects of an anti-lipogenic low-carbohydrate high polyunsaturated fat diet or a healthy Nordic diet versus usual care on liver fat and cardiometabolic disorders in type 2 diabetes or prediabetes: a randomized controlled trial (NAFLDiet)
- Download full text (pdf) of Effects of an anti-lipogenic low-carbohydrate high polyunsaturated fat diet or a healthy Nordic diet versus usual care on liver fat and cardiometabolic disorders in type 2 diabetes or prediabetes: a randomized controlled trial (NAFLDiet)
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Proteomic signatures for fibrosis in MASLD: a biopsy-proven dual-cohort study
Part of Scandinavian Journal of Gastroenterology, p. 597-605, 2025
- DOI for Proteomic signatures for fibrosis in MASLD: a biopsy-proven dual-cohort study
- Download full text (pdf) of Proteomic signatures for fibrosis in MASLD: a biopsy-proven dual-cohort study
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Part of Nature Medicine, p. 2867-2877, 2024
- DOI for Lipidome changes due to improved dietary fat quality inform cardiometabolic risk reduction and precision nutrition
- Download full text (pdf) of Lipidome changes due to improved dietary fat quality inform cardiometabolic risk reduction and precision nutrition
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Part of American Journal of Clinical Nutrition, p. 985-986, 2024
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Part of American Journal of Clinical Nutrition, p. 187-195, 2024
- DOI for Substitutions of saturated fat intakes with other macronutrients and foods and risk of NAFLD cirrhosis and all-cause hepatocellular carcinoma: a prospective cohort study
- Download full text (pdf) of Substitutions of saturated fat intakes with other macronutrients and foods and risk of NAFLD cirrhosis and all-cause hepatocellular carcinoma: a prospective cohort study
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Part of American Journal of Clinical Nutrition, p. 121-128, 2024
- DOI for Overfeeding polyunsaturated fat compared to saturated fat does not differentially influence lean tissue accumulation in overweight individuals: a randomized controlled trial
- Download full text (pdf) of Overfeeding polyunsaturated fat compared to saturated fat does not differentially influence lean tissue accumulation in overweight individuals: a randomized controlled trial
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Part of European Journal of Nutrition, p. 145-153, 2023
- DOI for Substitution analyses of foods with varying fat quality and the associations with all-cause mortality and impact of the FADS-1 genotype in elderly men
- Download full text (pdf) of Substitution analyses of foods with varying fat quality and the associations with all-cause mortality and impact of the FADS-1 genotype in elderly men
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Part of Journal of Nutrition, p. 683-690, 2023
- DOI for Contrasting Carbohydrate Quantity and Quality and the Effects on Plasma Saturated and Monounsaturated Fatty Acids in Healthy Adults: A Randomized Controlled Trial
- Download full text (pdf) of Contrasting Carbohydrate Quantity and Quality and the Effects on Plasma Saturated and Monounsaturated Fatty Acids in Healthy Adults: A Randomized Controlled Trial
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Part of Clinical Nutrition, p. 1922-1931, 2023
- DOI for Diet composition, nutrient substitutions and circulating fatty acids in relation to ectopic and visceral fat depots
- Download full text (pdf) of Diet composition, nutrient substitutions and circulating fatty acids in relation to ectopic and visceral fat depots
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Part of Clinical Nutrition, p. 2637-2643, 2022
- DOI for Circulating fatty acids from high-throughput metabolomics platforms as potential biomarkers of dietary fatty acids
- Download full text (pdf) of Circulating fatty acids from high-throughput metabolomics platforms as potential biomarkers of dietary fatty acids
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Part of Frontiers in nutrition, 2022
- DOI for Intake of Ultra-Processed Food and Ectopic-, Visceral- and Other Fat Depots: A Cross-Sectional Study.
- Download full text (pdf) of Intake of Ultra-Processed Food and Ectopic-, Visceral- and Other Fat Depots: A Cross-Sectional Study.
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Part of Frontiers in Medicine, 2022
- DOI for Hepatic Unsaturated Fatty Acids Are Linked to Lower Degree of Fibrosis in Non-alcoholic Fatty Liver Disease
- Download full text (pdf) of Hepatic Unsaturated Fatty Acids Are Linked to Lower Degree of Fibrosis in Non-alcoholic Fatty Liver Disease
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Part of Clinical Nutrition, p. 805-809, 2022
- DOI for Fatty acids in multiple circulating lipid fractions reflects the composition of liver triglycerides in humans
- Download full text (pdf) of Fatty acids in multiple circulating lipid fractions reflects the composition of liver triglycerides in humans
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Part of American Journal of Clinical Nutrition, p. 1743-1751, 2021
- DOI for Associations between fatty acid composition in serum cholesteryl esters and liver fat, basal fat oxidation, and resting energy expenditure: a population-based study
- Download full text (pdf) of Associations between fatty acid composition in serum cholesteryl esters and liver fat, basal fat oxidation, and resting energy expenditure: a population-based study
Articles, review/survey
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Part of BMC Medicine, 2026
- DOI for A systematic review of ultra-processed food subtypes and risk of type 2 diabetes, combined with a cohort analysis, question the utility of broad food classifications for public health policy
- Download full text (pdf) of A systematic review of ultra-processed food subtypes and risk of type 2 diabetes, combined with a cohort analysis, question the utility of broad food classifications for public health policy
Comprehensive doctoral thesis
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2024