Gull Rukh
Researcher at Department of Surgical Sciences; Functional Pharmacology and neuroscience
- E-mail:
- gull.rukh@neuro.uu.se
- Visiting address:
- BMC, Husargatan 3
751 24 Uppsala - Postal address:
- Kirurgiska vetenskaper, Box 593
751 24 Uppsala
Short presentation
My research explores the intersection of genetics, psychiatric traits, personality, and cardiometabolic health, with a focus on how these factors impact mental well-being and physical health, using large-scale cohort studies and Mendelian randomization. A key area of my current work addresses mental health challenges, especially among youth.

Publications
Recent publications
Part of Cephalalgia, p. 1-12, 2025
- DOI for Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism
- Download full text (pdf) of Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism
Part of Cortex, p. 211-219, 2025
- DOI for Associations between genetic variations in oxytocin pathway genes and hippocampal volume: Insights from the UK Biobank
- Download full text (pdf) of Associations between genetic variations in oxytocin pathway genes and hippocampal volume: Insights from the UK Biobank
Part of Diabetes, obesity and metabolism, p. 4734-4743, 2024
- DOI for LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans
- Download full text (pdf) of LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans
Part of Frontiers in Psychiatry, 2024
- DOI for Differential change in alcohol consumption during the COVID-19 pandemic: the role of loneliness, socialization, and mental well-being
- Download full text (pdf) of Differential change in alcohol consumption during the COVID-19 pandemic: the role of loneliness, socialization, and mental well-being
Part of Diabetes, obesity and metabolism, p. 3565-3575, 2024
- DOI for Genetic variants of LEAP2 are associated with anthropometric traits and circulating insulin-like growth factor-1 concentration: A UK Biobank study
- Download full text (pdf) of Genetic variants of LEAP2 are associated with anthropometric traits and circulating insulin-like growth factor-1 concentration: A UK Biobank study
All publications
Articles in journal
Part of Cephalalgia, p. 1-12, 2025
- DOI for Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism
- Download full text (pdf) of Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism
Part of Cortex, p. 211-219, 2025
- DOI for Associations between genetic variations in oxytocin pathway genes and hippocampal volume: Insights from the UK Biobank
- Download full text (pdf) of Associations between genetic variations in oxytocin pathway genes and hippocampal volume: Insights from the UK Biobank
Part of Diabetes, obesity and metabolism, p. 4734-4743, 2024
- DOI for LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans
- Download full text (pdf) of LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans
Part of Frontiers in Psychiatry, 2024
- DOI for Differential change in alcohol consumption during the COVID-19 pandemic: the role of loneliness, socialization, and mental well-being
- Download full text (pdf) of Differential change in alcohol consumption during the COVID-19 pandemic: the role of loneliness, socialization, and mental well-being
Part of Diabetes, obesity and metabolism, p. 3565-3575, 2024
- DOI for Genetic variants of LEAP2 are associated with anthropometric traits and circulating insulin-like growth factor-1 concentration: A UK Biobank study
- Download full text (pdf) of Genetic variants of LEAP2 are associated with anthropometric traits and circulating insulin-like growth factor-1 concentration: A UK Biobank study
Part of Journal of Molecular Neuroscience, 2024
- DOI for Genomic Validation in the UK Biobank Cohort Suggests a Role of C8B and MFG-E8 in the Pathogenesis of Trigeminal Neuralgia
- Download full text (pdf) of Genomic Validation in the UK Biobank Cohort Suggests a Role of C8B and MFG-E8 in the Pathogenesis of Trigeminal Neuralgia
Oxytocin pathway gene variation and corticostriatal resting-state functional connectivity
Part of COMPREHENSIVE PSYCHONEUROENDOCRINOLOGY, 2024
- DOI for Oxytocin pathway gene variation and corticostriatal resting-state functional connectivity
- Download full text (pdf) of Oxytocin pathway gene variation and corticostriatal resting-state functional connectivity
A deep learning model for brain age prediction using minimally preprocessed T1w images as input
Part of Frontiers in Aging Neuroscience, 2024
- DOI for A deep learning model for brain age prediction using minimally preprocessed T1w images as input
- Download full text (pdf) of A deep learning model for brain age prediction using minimally preprocessed T1w images as input
Part of Brain Communications, 2024
- DOI for Statin use is associated with higher white matter hyperintensity volumes and lower grey matter volumes
- Download full text (pdf) of Statin use is associated with higher white matter hyperintensity volumes and lower grey matter volumes
Part of Molecular Autism, 2024
- DOI for Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults
- Download full text (pdf) of Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults
Part of The journals of gerontology. Series A, Biological sciences and medical sciences, 2024
Job satisfaction and job tenure of people with mental health disorders: a UK Biobank cohort study
Part of Scandinavian Journal of Public Health, p. 1248-1257, 2023
- DOI for Job satisfaction and job tenure of people with mental health disorders: a UK Biobank cohort study
- Download full text (pdf) of Job satisfaction and job tenure of people with mental health disorders: a UK Biobank cohort study
Worsened Anxiety and Loneliness Influenced Gaming and Gambling during the COVID-19 Pandemic
Part of Journal of Clinical Medicine, 2023
- DOI for Worsened Anxiety and Loneliness Influenced Gaming and Gambling during the COVID-19 Pandemic
- Download full text (pdf) of Worsened Anxiety and Loneliness Influenced Gaming and Gambling during the COVID-19 Pandemic
Assessing volumetric brain differences in migraine and depression patients: a UK Biobank study
Part of BMC Neurology, 2023
- DOI for Assessing volumetric brain differences in migraine and depression patients: a UK Biobank study
- Download full text (pdf) of Assessing volumetric brain differences in migraine and depression patients: a UK Biobank study
Part of The journals of gerontology. Series A, Biological sciences and medical sciences, p. 1964-1972, 2023
- DOI for The Effects of Statins on Cognitive Performance Are Mediated by Low-Density Lipoprotein, C-Reactive Protein, and Blood Glucose Concentrations
- Download full text (pdf) of The Effects of Statins on Cognitive Performance Are Mediated by Low-Density Lipoprotein, C-Reactive Protein, and Blood Glucose Concentrations
Well-being spectrum traits are associated with polygenic scores for autism
Part of Autism Research, p. 1891-1902, 2023
- DOI for Well-being spectrum traits are associated with polygenic scores for autism
- Download full text (pdf) of Well-being spectrum traits are associated with polygenic scores for autism
Volumetric Differences in Cerebellum and Brainstem in Patients with Migraine: A UK Biobank Study
Part of Biomedicines, 2023
- DOI for Volumetric Differences in Cerebellum and Brainstem in Patients with Migraine: A UK Biobank Study
- Download full text (pdf) of Volumetric Differences in Cerebellum and Brainstem in Patients with Migraine: A UK Biobank Study
Migraine, inflammatory bowel disease and celiac disease: A Mendelian randomization study
Part of Headache, p. 642-651, 2023
- DOI for Migraine, inflammatory bowel disease and celiac disease: A Mendelian randomization study
- Download full text (pdf) of Migraine, inflammatory bowel disease and celiac disease: A Mendelian randomization study
Part of NeuroImage, 2023
- DOI for Higher fresh fruit intake relates to larger grey matter volumes in areas involved in dementia and depression: A UK Biobank study
- Download full text (pdf) of Higher fresh fruit intake relates to larger grey matter volumes in areas involved in dementia and depression: A UK Biobank study
Part of Journal of personality, p. 856-867, 2023
- DOI for Effect of worry, depression, and sensitivity to environmental stress owing to neurotic personality on risk of cardiovascular disease: A Mendelian randomization study
- Download full text (pdf) of Effect of worry, depression, and sensitivity to environmental stress owing to neurotic personality on risk of cardiovascular disease: A Mendelian randomization study
Job satisfaction has differential associations with delay discounting and risk-taking
Part of Scientific Reports, 2023
- DOI for Job satisfaction has differential associations with delay discounting and risk-taking
- Download full text (pdf) of Job satisfaction has differential associations with delay discounting and risk-taking
Part of Frontiers in Genetics, 2022
- DOI for Evidence of a Causal Link Between the Well-Being Spectrum and the Risk of Myocardial Infarction: A Mendelian Randomization Study
- Download full text (pdf) of Evidence of a Causal Link Between the Well-Being Spectrum and the Risk of Myocardial Infarction: A Mendelian Randomization Study
The influence of personality on the risk of myocardial infarction in UK Biobank cohort
Part of Scientific Reports, 2022
- DOI for The influence of personality on the risk of myocardial infarction in UK Biobank cohort
- Download full text (pdf) of The influence of personality on the risk of myocardial infarction in UK Biobank cohort
Association of Diligence and Sociability with Stroke: A UK Biobank Study on Personality Proxies
Part of FRONTIERS IN BIOSCIENCE-LANDMARK, 2022
- DOI for Association of Diligence and Sociability with Stroke: A UK Biobank Study on Personality Proxies
- Download full text (pdf) of Association of Diligence and Sociability with Stroke: A UK Biobank Study on Personality Proxies
Migraine and gastrointestinal disorders in middle and old age: A UK Biobank study
Part of Brain and Behavior, 2021
- DOI for Migraine and gastrointestinal disorders in middle and old age: A UK Biobank study
- Download full text (pdf) of Migraine and gastrointestinal disorders in middle and old age: A UK Biobank study
Part of Nutrients, 2021
- DOI for Depression and Vegetarians: Association between Dietary Vitamin B6, B12 and Folate Intake and Global and Subcortical Brain Volumes
- Download full text (pdf) of Depression and Vegetarians: Association between Dietary Vitamin B6, B12 and Folate Intake and Global and Subcortical Brain Volumes
Part of Environmental Research, 2021
- DOI for Time spent outdoors and risk of myocardial infarction and stroke in middle and old aged adults: Results from the UK Biobank prospective cohort
- Download full text (pdf) of Time spent outdoors and risk of myocardial infarction and stroke in middle and old aged adults: Results from the UK Biobank prospective cohort
Part of Frontiers in Bioscience-Landmark, p. 1453-1463, 2021
- DOI for Differential associations of statin treatment and polymorphism in genes coding for HMGCR and PCSK9 to risk for insomnia
- Download full text (pdf) of Differential associations of statin treatment and polymorphism in genes coding for HMGCR and PCSK9 to risk for insomnia
Part of Biomedicine and Pharmacotherapy, 2021
- DOI for Association between migraine prevalence, treatment with proton-pump inhibitors and CYP2C19 phenotypes in UK Biobank
- Download full text (pdf) of Association between migraine prevalence, treatment with proton-pump inhibitors and CYP2C19 phenotypes in UK Biobank
Part of Translational Psychiatry, 2020
- DOI for Personality, lifestyle and job satisfaction: causal association between neuroticism and job satisfaction using Mendelian randomisation in the UK biobank cohort
- Download full text (pdf) of Personality, lifestyle and job satisfaction: causal association between neuroticism and job satisfaction using Mendelian randomisation in the UK biobank cohort
Part of International Journal of Environmental Research and Public Health, 2020
- DOI for Important Difference between Occupational Hazard Exposure among Shift Workers and Other Workers; Comparing Workplace before and after 1980
- Download full text (pdf) of Important Difference between Occupational Hazard Exposure among Shift Workers and Other Workers; Comparing Workplace before and after 1980
Articles, review/survey
Part of Frontiers in Neuroscience, 2024
- DOI for Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology
- Download full text (pdf) of Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology
Part of Journal of genetics and genomics = Yi chuan xue bao, p. 1-12, 2022
Part of Frontiers in Endocrinology, 2019
- DOI for Gene Lifestyle Interactions With Relation to Obesity, Cardiometabolic, and Cardiovascular Traits Among South Asians
- Download full text (pdf) of Gene Lifestyle Interactions With Relation to Obesity, Cardiometabolic, and Cardiovascular Traits Among South Asians