Gull Rukh
Researcher at Department of Surgical Sciences; Functional Pharmacology and neuroscience
- E-mail:
- gull.rukh@neuro.uu.se
- Visiting address:
- BMC, Husargatan 3
751 24 Uppsala - Postal address:
- Kirurgiska vetenskaper, Box 593
751 24 Uppsala
Short presentation
My research explores the intersection of genetics, psychiatric traits, personality, and cardiometabolic health, with a focus on how these factors impact mental well-being and physical health, using large-scale cohort studies and Mendelian randomization. A key area of my current work addresses mental health challenges, especially among youth.
Publications
Recent publications
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Part of Psychiatry Research, 2026
- DOI for Parental support moderates the interaction of COMT and BDNF genotypes with early life adversity on problem gambling severity index scores among young adults
- Download full text (pdf) of Parental support moderates the interaction of COMT and BDNF genotypes with early life adversity on problem gambling severity index scores among young adults
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Gene-environment interactions in the pathogenesis of cardiovascular disease
Part of Nature Reviews Cardiology, p. 8-8, 2026
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Part of Heliyon, 2025
- DOI for Identification and validation of depression-associated genetic variants in the UK Biobank cohort with transcriptome and DNA methylation analyses in independent cohorts
- Download full text (pdf) of Identification and validation of depression-associated genetic variants in the UK Biobank cohort with transcriptome and DNA methylation analyses in independent cohorts
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Part of Journal of Cachexia, Sarcopenia and Muscle, 2025
- DOI for Statin Use Is Associated With a Decline in Muscle Function and Mass Over Time, Irrespective of Statin Pharmacogenomic Score
- Download full text (pdf) of Statin Use Is Associated With a Decline in Muscle Function and Mass Over Time, Irrespective of Statin Pharmacogenomic Score
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Part of Cephalalgia, p. 1-12, 2025
- DOI for Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism
- Download full text (pdf) of Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism
All publications
Articles in journal
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Part of Psychiatry Research, 2026
- DOI for Parental support moderates the interaction of COMT and BDNF genotypes with early life adversity on problem gambling severity index scores among young adults
- Download full text (pdf) of Parental support moderates the interaction of COMT and BDNF genotypes with early life adversity on problem gambling severity index scores among young adults
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Gene-environment interactions in the pathogenesis of cardiovascular disease
Part of Nature Reviews Cardiology, p. 8-8, 2026
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Part of Heliyon, 2025
- DOI for Identification and validation of depression-associated genetic variants in the UK Biobank cohort with transcriptome and DNA methylation analyses in independent cohorts
- Download full text (pdf) of Identification and validation of depression-associated genetic variants in the UK Biobank cohort with transcriptome and DNA methylation analyses in independent cohorts
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Part of Journal of Cachexia, Sarcopenia and Muscle, 2025
- DOI for Statin Use Is Associated With a Decline in Muscle Function and Mass Over Time, Irrespective of Statin Pharmacogenomic Score
- Download full text (pdf) of Statin Use Is Associated With a Decline in Muscle Function and Mass Over Time, Irrespective of Statin Pharmacogenomic Score
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Part of Cephalalgia, p. 1-12, 2025
- DOI for Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism
- Download full text (pdf) of Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism
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Part of Cortex, p. 211-219, 2025
- DOI for Associations between genetic variations in oxytocin pathway genes and hippocampal volume: Insights from the UK Biobank
- Download full text (pdf) of Associations between genetic variations in oxytocin pathway genes and hippocampal volume: Insights from the UK Biobank
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Part of Frontiers in Psychiatry, 2024
- DOI for Differential change in alcohol consumption during the COVID-19 pandemic: the role of loneliness, socialization, and mental well-being
- Download full text (pdf) of Differential change in alcohol consumption during the COVID-19 pandemic: the role of loneliness, socialization, and mental well-being
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Part of Diabetes, obesity and metabolism, p. 4734-4743, 2024
- DOI for LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans
- Download full text (pdf) of LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans
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Part of Diabetes, obesity and metabolism, p. 3565-3575, 2024
- DOI for Genetic variants of LEAP2 are associated with anthropometric traits and circulating insulin-like growth factor-1 concentration: A UK Biobank study
- Download full text (pdf) of Genetic variants of LEAP2 are associated with anthropometric traits and circulating insulin-like growth factor-1 concentration: A UK Biobank study
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Part of Journal of Molecular Neuroscience, 2024
- DOI for Genomic Validation in the UK Biobank Cohort Suggests a Role of C8B and MFG-E8 in the Pathogenesis of Trigeminal Neuralgia
- Download full text (pdf) of Genomic Validation in the UK Biobank Cohort Suggests a Role of C8B and MFG-E8 in the Pathogenesis of Trigeminal Neuralgia
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Oxytocin pathway gene variation and corticostriatal resting-state functional connectivity
Part of COMPREHENSIVE PSYCHONEUROENDOCRINOLOGY, 2024
- DOI for Oxytocin pathway gene variation and corticostriatal resting-state functional connectivity
- Download full text (pdf) of Oxytocin pathway gene variation and corticostriatal resting-state functional connectivity
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A deep learning model for brain age prediction using minimally preprocessed T1w images as input
Part of Frontiers in Aging Neuroscience, 2024
- DOI for A deep learning model for brain age prediction using minimally preprocessed T1w images as input
- Download full text (pdf) of A deep learning model for brain age prediction using minimally preprocessed T1w images as input
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Part of Brain Communications, 2024
- DOI for Statin use is associated with higher white matter hyperintensity volumes and lower grey matter volumes
- Download full text (pdf) of Statin use is associated with higher white matter hyperintensity volumes and lower grey matter volumes
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Part of Molecular Autism, 2024
- DOI for Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults
- Download full text (pdf) of Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults
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Part of The journals of gerontology. Series A, Biological sciences and medical sciences, 2024
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Worsened Anxiety and Loneliness Influenced Gaming and Gambling during the COVID-19 Pandemic
Part of Journal of Clinical Medicine, 2023
- DOI for Worsened Anxiety and Loneliness Influenced Gaming and Gambling during the COVID-19 Pandemic
- Download full text (pdf) of Worsened Anxiety and Loneliness Influenced Gaming and Gambling during the COVID-19 Pandemic
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Job satisfaction and job tenure of people with mental health disorders: a UK Biobank cohort study
Part of Scandinavian Journal of Public Health, p. 1248-1257, 2023
- DOI for Job satisfaction and job tenure of people with mental health disorders: a UK Biobank cohort study
- Download full text (pdf) of Job satisfaction and job tenure of people with mental health disorders: a UK Biobank cohort study
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Assessing volumetric brain differences in migraine and depression patients: a UK Biobank study
Part of BMC Neurology, 2023
- DOI for Assessing volumetric brain differences in migraine and depression patients: a UK Biobank study
- Download full text (pdf) of Assessing volumetric brain differences in migraine and depression patients: a UK Biobank study
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Part of The journals of gerontology. Series A, Biological sciences and medical sciences, p. 1964-1972, 2023
- DOI for The Effects of Statins on Cognitive Performance Are Mediated by Low-Density Lipoprotein, C-Reactive Protein, and Blood Glucose Concentrations
- Download full text (pdf) of The Effects of Statins on Cognitive Performance Are Mediated by Low-Density Lipoprotein, C-Reactive Protein, and Blood Glucose Concentrations
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Well-being spectrum traits are associated with polygenic scores for autism
Part of Autism Research, p. 1891-1902, 2023
- DOI for Well-being spectrum traits are associated with polygenic scores for autism
- Download full text (pdf) of Well-being spectrum traits are associated with polygenic scores for autism
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Volumetric Differences in Cerebellum and Brainstem in Patients with Migraine: A UK Biobank Study
Part of Biomedicines, 2023
- DOI for Volumetric Differences in Cerebellum and Brainstem in Patients with Migraine: A UK Biobank Study
- Download full text (pdf) of Volumetric Differences in Cerebellum and Brainstem in Patients with Migraine: A UK Biobank Study
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Migraine, inflammatory bowel disease and celiac disease: A Mendelian randomization study
Part of Headache, p. 642-651, 2023
- DOI for Migraine, inflammatory bowel disease and celiac disease: A Mendelian randomization study
- Download full text (pdf) of Migraine, inflammatory bowel disease and celiac disease: A Mendelian randomization study
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Part of NeuroImage, 2023
- DOI for Higher fresh fruit intake relates to larger grey matter volumes in areas involved in dementia and depression: A UK Biobank study
- Download full text (pdf) of Higher fresh fruit intake relates to larger grey matter volumes in areas involved in dementia and depression: A UK Biobank study
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Part of Journal of personality, p. 856-867, 2023
- DOI for Effect of worry, depression, and sensitivity to environmental stress owing to neurotic personality on risk of cardiovascular disease: A Mendelian randomization study
- Download full text (pdf) of Effect of worry, depression, and sensitivity to environmental stress owing to neurotic personality on risk of cardiovascular disease: A Mendelian randomization study
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Job satisfaction has differential associations with delay discounting and risk-taking
Part of Scientific Reports, 2023
- DOI for Job satisfaction has differential associations with delay discounting and risk-taking
- Download full text (pdf) of Job satisfaction has differential associations with delay discounting and risk-taking
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The influence of personality on the risk of myocardial infarction in UK Biobank cohort
Part of Scientific Reports, 2022
- DOI for The influence of personality on the risk of myocardial infarction in UK Biobank cohort
- Download full text (pdf) of The influence of personality on the risk of myocardial infarction in UK Biobank cohort
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Part of Frontiers in Genetics, 2022
- DOI for Evidence of a Causal Link Between the Well-Being Spectrum and the Risk of Myocardial Infarction: A Mendelian Randomization Study
- Download full text (pdf) of Evidence of a Causal Link Between the Well-Being Spectrum and the Risk of Myocardial Infarction: A Mendelian Randomization Study
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Association of Diligence and Sociability with Stroke: A UK Biobank Study on Personality Proxies
Part of FRONTIERS IN BIOSCIENCE-LANDMARK, 2022
- DOI for Association of Diligence and Sociability with Stroke: A UK Biobank Study on Personality Proxies
- Download full text (pdf) of Association of Diligence and Sociability with Stroke: A UK Biobank Study on Personality Proxies
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Migraine and gastrointestinal disorders in middle and old age: A UK Biobank study
Part of Brain and Behavior, 2021
- DOI for Migraine and gastrointestinal disorders in middle and old age: A UK Biobank study
- Download full text (pdf) of Migraine and gastrointestinal disorders in middle and old age: A UK Biobank study
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Part of Nutrients, 2021
- DOI for Depression and Vegetarians: Association between Dietary Vitamin B6, B12 and Folate Intake and Global and Subcortical Brain Volumes
- Download full text (pdf) of Depression and Vegetarians: Association between Dietary Vitamin B6, B12 and Folate Intake and Global and Subcortical Brain Volumes
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Part of Environmental Research, 2021
- DOI for Time spent outdoors and risk of myocardial infarction and stroke in middle and old aged adults: Results from the UK Biobank prospective cohort
- Download full text (pdf) of Time spent outdoors and risk of myocardial infarction and stroke in middle and old aged adults: Results from the UK Biobank prospective cohort
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Part of Frontiers in Bioscience-Landmark, p. 1453-1463, 2021
- DOI for Differential associations of statin treatment and polymorphism in genes coding for HMGCR and PCSK9 to risk for insomnia
- Download full text (pdf) of Differential associations of statin treatment and polymorphism in genes coding for HMGCR and PCSK9 to risk for insomnia
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Part of Biomedicine and Pharmacotherapy, 2021
- DOI for Association between migraine prevalence, treatment with proton-pump inhibitors and CYP2C19 phenotypes in UK Biobank
- Download full text (pdf) of Association between migraine prevalence, treatment with proton-pump inhibitors and CYP2C19 phenotypes in UK Biobank
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Part of Translational Psychiatry, 2020
- DOI for Personality, lifestyle and job satisfaction: causal association between neuroticism and job satisfaction using Mendelian randomisation in the UK biobank cohort
- Download full text (pdf) of Personality, lifestyle and job satisfaction: causal association between neuroticism and job satisfaction using Mendelian randomisation in the UK biobank cohort
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Part of International Journal of Environmental Research and Public Health, 2020
- DOI for Important Difference between Occupational Hazard Exposure among Shift Workers and Other Workers; Comparing Workplace before and after 1980
- Download full text (pdf) of Important Difference between Occupational Hazard Exposure among Shift Workers and Other Workers; Comparing Workplace before and after 1980
Articles, review/survey
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Part of Frontiers in Neuroscience, 2024
- DOI for Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology
- Download full text (pdf) of Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology
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Part of Journal of genetics and genomics = Yi chuan xue bao, p. 1-12, 2022
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Part of Frontiers in Endocrinology, 2019
- DOI for Gene Lifestyle Interactions With Relation to Obesity, Cardiometabolic, and Cardiovascular Traits Among South Asians
- Download full text (pdf) of Gene Lifestyle Interactions With Relation to Obesity, Cardiometabolic, and Cardiovascular Traits Among South Asians