Philippe Wernet
Professor at Department of Physics and Astronomy; X-ray Photon Science
- Telephone:
- +46 18 471 35 40
- Mobile phone:
- +46 72 999 97 07
- E-mail:
- philippe.wernet@physics.uu.se
- Visiting address:
- Ångströmlaboratoriet, Regementsvägen 10
752 37 Uppsala - Postal address:
- Box 516
751 20 UPPSALA
Professor at Department of Physics and Astronomy; X-ray Photon Science; Chemical and Bio-Molecular Physics
- Telephone:
- +46 18 471 35 40
- Mobile phone:
- +46 72 999 97 07
- E-mail:
- philippe.wernet@physics.uu.se
- Visiting address:
- Ångströmlaboratoriet, Regementsvägen 10
752 37 Uppsala - Postal address:
- Box 516
751 20 UPPSALA
- ORCID:
- 0000-0001-7011-9072
Short presentation
I watch chemical reactions as they take place. X-ray lasers, synchrotrons and lab sources with short X-ray pulses are my high-speed cameras. I use them to select which atomic site in a molecule I look at and which orbital I follow in real time of the reaction. I study small molecules, metal complexes and metalloenzymes to discover basic principles that drive their transformations and that determine how they work.
Read our Science paper and see our program on Chemical and Bio-Molecular Physics.
Biography
Since 2021 Head of the Chemical and Bio-Molecular Physics research program at the Department of Physics and Astronomy at Uppsala University
Since 2019 Professor in Photon Science at the Department of Physics and Astronomy at Uppsala University
2003 - 2019 Staff scientist at Helmholtz-Zentrum Berlin (BESSY II, Berlin, Germany)
2012 Habilitation in physics at Technische Universität Berlin (Germany)
2001 - 2002 Postdoc at the Stanford Synchrotron Radiation Laboratory (SSRL, Stanford, USA)
2000 Postdoc at Deutsches Elektronen-Synchrotron (DESY, Hamburg, Germany)
2000 PhD in experimental physics at Universität Hamburg (Germany)
Serving in the Scientific Advisory Committees at the European XFEL (Hamburg, Germany) and at Elettra Sincrotrone Trieste (Italy).
Research
We are working on three main topics:
- Coupling of electronic, spin and nuclear coordinates in the photo-induced dynamics of molecules
- Photochemical bond activation by metal complexes
- Local chemistry of bond-activating metalloproteins
We want to understand, predict and ultimately control the excited-state dynamics of molecules and metal complexes. Probing the coupling of transient electronic structure and nuclear dynamics forms the basis for understanding photocatalytic processes.
We want to explain how metal complexes activate inert bonds. Developing a fundamental understanding of bond activation is the first step of learning how to engineer chemical bonds.
We want to probe the chemical interactions of metal atoms and ions in metalloproteins and how these evolve during a reaction. Learning from nature how to efficiently transform molecules will help us develop new concepts for catalysis.
The foundation of our research is to find new ways of coupling experiments and theory in x-ray spectroscopy. We develop new experimental methods at large-scale x-ray facilities and at lab-based x-ray sources. We want to make available new observables and we work closely with theory groups in quantum chemistry and molecular dynamics to further extend the information content of x-ray spectroscopy.
Our research is part of the Chemical and Bio-Molecular Physics research program.

Publications
Selection of publications
Resonant Inelastic X-ray Scattering (RIXS) Studies in Chemistry: Present and Future
Part of Synchrotron Light Sources and Free-Electron Lasers, Springer, 2019
- DOI for Resonant Inelastic X-ray Scattering (RIXS) Studies in Chemistry: Present and Future
- Download full text (pdf) of Resonant Inelastic X-ray Scattering (RIXS) Studies in Chemistry: Present and Future
Part of Philosophical Transactions of the Royal Society A, p. 1-29, 2019
Orbital-specific Mapping of Chemical Interactions and Dynamics with Femtosecond Soft X-ray Pulses
Part of X-Ray Free Electron Lasers, p. 242-263, Royal Society of Chemistry, 2017
Orbital-specific mapping of the ligand exchange dynamics of Fe(CO)5 in solution
Part of Nature, p. 78-81, 2015
Temperature Dependent Soft X-ray Absorption Spectroscopy of Liquids
Part of Review of Scientific Instruments, 2014
A sample holder for soft x-ray absorption spectroscopy of liquids in transmission mode
Part of Review of Scientific Instruments, 2011
Recent publications
X-ray absorption spectroscopy of a coordinatively unsaturated 3d transition metal complex
Part of Journal of Chemical Physics, 2025
- DOI for X-ray absorption spectroscopy of a coordinatively unsaturated 3d transition metal complex
- Download full text (pdf) of X-ray absorption spectroscopy of a coordinatively unsaturated 3d transition metal complex
Probing soft X-ray induced photoreduction of a model Mn-complex at cryogenic conditions
Part of Journal of Synchrotron Radiation, p. 399-407, 2025
- DOI for Probing soft X-ray induced photoreduction of a model Mn-complex at cryogenic conditions
- Download full text (pdf) of Probing soft X-ray induced photoreduction of a model Mn-complex at cryogenic conditions
Automated spectrometer alignment via machine learning
Part of Journal of Synchrotron Radiation, p. 698-705, 2024
- DOI for Automated spectrometer alignment via machine learning
- Download full text (pdf) of Automated spectrometer alignment via machine learning
Part of The Journal of Physical Chemistry Letters, p. 11830-11838, 2024
- DOI for Different Photodissociation Mechanisms in Fe(CO)5 and Cr(CO)6 Evidenced with Femtosecond Valence Photoelectron Spectroscopy and Excited-State Molecular Dynamics Simulations
- Download full text (pdf) of Different Photodissociation Mechanisms in Fe(CO)5 and Cr(CO)6 Evidenced with Femtosecond Valence Photoelectron Spectroscopy and Excited-State Molecular Dynamics Simulations
Part of Inorganic Chemistry, p. 10634-10647, 2024
- DOI for Theoretical Investigation of Transient Species Following Photodissociation of Ironpentacarbonyl in Ethanol Solution
- Download full text (pdf) of Theoretical Investigation of Transient Species Following Photodissociation of Ironpentacarbonyl in Ethanol Solution
All publications
Articles in journal
X-ray absorption spectroscopy of a coordinatively unsaturated 3d transition metal complex
Part of Journal of Chemical Physics, 2025
- DOI for X-ray absorption spectroscopy of a coordinatively unsaturated 3d transition metal complex
- Download full text (pdf) of X-ray absorption spectroscopy of a coordinatively unsaturated 3d transition metal complex
Probing soft X-ray induced photoreduction of a model Mn-complex at cryogenic conditions
Part of Journal of Synchrotron Radiation, p. 399-407, 2025
- DOI for Probing soft X-ray induced photoreduction of a model Mn-complex at cryogenic conditions
- Download full text (pdf) of Probing soft X-ray induced photoreduction of a model Mn-complex at cryogenic conditions
Automated spectrometer alignment via machine learning
Part of Journal of Synchrotron Radiation, p. 698-705, 2024
- DOI for Automated spectrometer alignment via machine learning
- Download full text (pdf) of Automated spectrometer alignment via machine learning
Part of The Journal of Physical Chemistry Letters, p. 11830-11838, 2024
- DOI for Different Photodissociation Mechanisms in Fe(CO)5 and Cr(CO)6 Evidenced with Femtosecond Valence Photoelectron Spectroscopy and Excited-State Molecular Dynamics Simulations
- Download full text (pdf) of Different Photodissociation Mechanisms in Fe(CO)5 and Cr(CO)6 Evidenced with Femtosecond Valence Photoelectron Spectroscopy and Excited-State Molecular Dynamics Simulations
Part of Inorganic Chemistry, p. 10634-10647, 2024
- DOI for Theoretical Investigation of Transient Species Following Photodissociation of Ironpentacarbonyl in Ethanol Solution
- Download full text (pdf) of Theoretical Investigation of Transient Species Following Photodissociation of Ironpentacarbonyl in Ethanol Solution
Part of Journal of the American Chemical Society, p. 14000-14011, 2024
- DOI for Photochemical Formation and Electronic Structure of an Alkane σ-Complex from Time-Resolved Optical and X-ray Absorption Spectroscopy
- Download full text (pdf) of Photochemical Formation and Electronic Structure of an Alkane σ-Complex from Time-Resolved Optical and X-ray Absorption Spectroscopy
Part of Chemical Science, p. 2398-2409, 2024
- DOI for Accessing metal-specific orbital interactions in C–H activation with resonant inelastic X-ray scattering
- Download full text (pdf) of Accessing metal-specific orbital interactions in C–H activation with resonant inelastic X-ray scattering
A Δ-learning strategy for interpretation of spectroscopic observables
Part of Structural Dynamics, 2023
- DOI for A Δ-learning strategy for interpretation of spectroscopic observables
- Download full text (pdf) of A Δ-learning strategy for interpretation of spectroscopic observables
Tracking C–H activation with orbital resolution
Part of Science, p. 955-960, 2023
Part of Nature Communications, 2022
- DOI for Photoinduced bond oscillations in ironpentacarbonyl give delayed synchronous bursts of carbonmonoxide release
- Download full text (pdf) of Photoinduced bond oscillations in ironpentacarbonyl give delayed synchronous bursts of carbonmonoxide release
From Local Covalent Bonding to Extended Electric Field Interactions in Proton Hydration
Part of Angewandte Chemie International Edition, 2022
- DOI for From Local Covalent Bonding to Extended Electric Field Interactions in Proton Hydration
- Download full text (pdf) of From Local Covalent Bonding to Extended Electric Field Interactions in Proton Hydration
Electronic Structure Changes of an Aromatic Amine Photoacid along the Forster Cycle
Part of Angewandte Chemie International Edition, 2022
- DOI for Electronic Structure Changes of an Aromatic Amine Photoacid along the Forster Cycle
- Download full text (pdf) of Electronic Structure Changes of an Aromatic Amine Photoacid along the Forster Cycle
Part of The Journal of Physical Chemistry Letters, p. 6676-6683, 2021
Part of Communications Chemistry, 2021
- DOI for Resonant X-ray emission spectroscopy from broadband stochastic pulses at an X-ray free electron laser
- Download full text (pdf) of Resonant X-ray emission spectroscopy from broadband stochastic pulses at an X-ray free electron laser
Part of Philosophical Transactions of the Royal Society A, p. 1-29, 2019
Part of Inorganic Chemistry, p. 5449-5462, 2018
- DOI for Direct Determination of Absolute Absorption Cross Sections at the L-Edge of Dilute Mn Complexes in Solution Using a Transmission Flatjet
- Download full text (pdf) of Direct Determination of Absolute Absorption Cross Sections at the L-Edge of Dilute Mn Complexes in Solution Using a Transmission Flatjet
Part of Structural Dynamics, 2017
- DOI for Soft x-ray absorption spectroscopy of metalloproteins and high-valent metal-complexes at room temperature using free-electron lasers
- Download full text (pdf) of Soft x-ray absorption spectroscopy of metalloproteins and high-valent metal-complexes at room temperature using free-electron lasers
Part of Journal of Physical Chemistry B, p. 7182-7194, 2016
- DOI for Viewing the Valence Electronic Structure of Ferric and Ferrous Hexacyanide in Solution from the Fe and Cyanide Perspectives
- Download full text (pdf) of Viewing the Valence Electronic Structure of Ferric and Ferrous Hexacyanide in Solution from the Fe and Cyanide Perspectives
Orbital-specific mapping of the ligand exchange dynamics of Fe(CO)5 in solution
Part of Nature, p. 78-81, 2015
Temperature Dependent Soft X-ray Absorption Spectroscopy of Liquids
Part of Review of Scientific Instruments, 2014
A sample holder for soft x-ray absorption spectroscopy of liquids in transmission mode
Part of Review of Scientific Instruments, 2011
Articles, review/survey
Part of Annual review of physical chemistry (Print), p. 187-208, 2022
Using X-ray free-electron lasers for spectroscopy of molecular catalysts and metalloenzymes
Part of NATURE REVIEWS PHYSICS, p. 264-282, 2021
Chapters in book
Resonant Inelastic X-ray Scattering (RIXS) Studies in Chemistry: Present and Future
Part of Synchrotron Light Sources and Free-Electron Lasers, Springer, 2019
- DOI for Resonant Inelastic X-ray Scattering (RIXS) Studies in Chemistry: Present and Future
- Download full text (pdf) of Resonant Inelastic X-ray Scattering (RIXS) Studies in Chemistry: Present and Future
Orbital-specific Mapping of Chemical Interactions and Dynamics with Femtosecond Soft X-ray Pulses
Part of X-Ray Free Electron Lasers, p. 242-263, Royal Society of Chemistry, 2017